产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
Anti-Heme Oxygenase 1/HMOX1 Antibody Picoband™
目录 :
PB9212
规格 :
100μg/vial
价格 :
315美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫组化-石蜡切片
图像
图像 1 :
武汉博士德生物工程有限公司 PB9212 图像 1
Anti- HMOX1 antibody, PB9212, Western blotting. All lanes: Anti HMOX1 (PB9212) at 0.5ug/ml. WB: Recombinant Human HMOX1 Protein 0.5ng. Predicted bind size: 37KD. Observed bind size: 37KD
图像 2 :
武汉博士德生物工程有限公司 PB9212 图像 2
Anti- HMOX1 antibody, PB9212, Western blotting. All lanes: Anti HMOX1 (PB9212) at 0.5ug/ml. Lane 1: Human Placenta Tissue Lysate at 50ug. Lane 2: Rat Spleen Tissue Lysate at 50ug. Lane 3: A549 Whole Cell Lysate at 40ug. Lane 4: PANC Whole Cell Lysate at 40ug. Lane 5: HELA Whole Cell Lysate at 40ug. Predicted bind size: 33KD. Observed bind size: 33KD
产品信息
SKU号 :
PB9212
产品名称 :
Anti-Heme Oxygenase 1/HMOX1 Antibody Picoband™
价格 :
315美元
规格 :
100μg/vial
克隆性 :
多克隆
宿主 :
反应物种 :
人类
应用(s) :
免疫组化-P, 免疫印迹
应用细节 :
免疫印迹, 0.1 0.5µg/毫升, 人类。 免疫组化(石蜡包埋切片), 2-5微克/毫升, 人类
应用注释 :
WB: The detection limit for HMOX1 is approximately 0.2ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
描述 :
Boster Bio Anti-Heme Oxygenase 1/HMOX1 Antibody Picoband™ catalog # PB9212. Tested in IHC-P, WB applications. This antibody reacts with Human.
浓度 :
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
基因名称 :
HMOX1
UniProt数据库编号 :
P09601
免疫原 :
E.coli-derived human HMOX1 recombinant protein (Position: M1-M288). Human HMOX1 shares 82% and 80% amino acid (aa) sequences identity with mouse and rat HMOX1, respectively.
形式 :
冻干
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
纯化 :
免疫原亲和纯化
交叉活性 :
No cross reactivity with other proteins
储存 :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
基因全称 :
血红素氧化酶
同义词 :
血红素氧化酶;HO-1;1.14.99.3;HMOX1;HO, HO1;
蛋白名 :
血红素氧化酶
分子量 :
32819分子量
Protein Function :
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
Subcellular Localization :
Microsome. Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side.
组织特异性 :
Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level).
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Sequence Similarities :
Belongs to the heme oxygenase family.
背景 :
HMOX1 (heme oxygenase (decycling) 1), also known as HO-1, is a human gene that encodes for the enzyme heme oxygenase 1. It is an essential enzyme in heme catabolism, it cleaves heme to form biliverdin. HMOX1 belongs to the heme oxygenase family. The HMOX1 gene is located on the long (q) arm of chromosome 22 at position 12.3, from base pair 34,101,636 to base pair 34,114,748. HMOX1, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. HMOX1 activity is induced by its substrate heme and by various nonheme substances.
研究种类 :
Atherosclerosis, Cancer, Cancer Metabolism, Cardiovascular, Epigenetics and Nuclear Signaling, Heart Disease, Metabolism, Metabolism Processes, Neurodegenerative Disease, Neurology Process, Neuroscience, Nfkb Pathway, Nuclear Signaling, Nuclear Signaling Pathways, Pathways And Processes, Platelets, Response To Hypoxia, Signal Transduction, Signaling Pathway, Vascular Inflammation, Vasculature
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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