产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
Anti-p73/TP73 Picoband Antibody
目录 :
PB9235
规格 :
100 ug/vial
价格 :
280美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化
图像
图像 1 :
武汉博士德生物工程有限公司 PB9235 图像 1
Anti- p73 antibody, PB9235, Western blotting. All lanes: Anti p73 (PB9235) at 0.5ug/ml. WB: Recombinant Human p73 Protein 0.5ng. Predicted bind size: 45KD. Observed bind size: 45KD
图像 2 :
武汉博士德生物工程有限公司 PB9235 图像 2
Anti- p73 antibody, PB9235, Western blotting. All lanes: Anti p73 (PB9235) at 0.5ug/ml. Lane 1: HELA Whole Cell Lysate at 40ug. Lane 2: MCF-7 Whole Cell Lysate at 40ug. Lane 3: COLO320 Whole Cell Lysate at 40ug. Predicted bind size: 73KD. Observed bind size: 73KD
图像 3 :
武汉博士德生物工程有限公司 PB9235 图像 3
Anti- p73 antibody, PB9235, IHC(P). IHC(P): Human Intestinal Cancer Tissue
产品信息
SKU号 :
PB9235
状态 :
Enabled
名称 :
Anti-p73/TP73 Picoband Antibody
目录名称 :
一抗, 多克隆抗体, 免疫组化免疫细胞化学IF抗体
基因名称 :
TP73
价格 :
280美元
price various sizes :
Unconjugated / $280 APC / $330 APC-Cy7 / $330 FITC / $330 PE / $330 PE-Cy5 / $330 PE-Cy7 / $330 30ug sample size / $99 100ug / $280 100ug+Free HRP Secondary BA1054 / $280 100ug+Free Biotin Secondary BA1003 / $280
克隆性 :
多克隆
浓度 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
共轭标签 :
No
contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
描述 :
Polyclonal antibody for P73/TP73 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IHC-P. Reactive species: Human. P73/TP73 information: Molecular Weight: 69623 MW; Subcellular Localization: Nucleus . Cytoplasm. Accumulates in the nucleus in response to DNA damage; Tissue Specificity: Expressed in striatal neurons of patients with Huntington disease (at protein level). Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue.
short description :
Rabbit IgG polyclonal antibody for Tumor protein p73(TP73) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
规格 :
100 ug/vial
sample size available :
30ug for $99, contact us for details
UniProt数据库编号 :
O15350
宿主 :
免疫原 :
E.coli-derived human p73 recombinant protein (Position: M1-E198). Human p73 shares 96% amino acid (aa) sequence identity with mouse p73.
形式 :
冻干
纯化 :
免疫原亲和纯化
储存 :
At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time. Avoid repeated freezing and thawing.
交叉活性 :
No cross reactivity with other proteins
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
应用细节 :
Immunohistochemistry(Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat. Western blot, 0.1-0.5ug/ml, Human.
应用 :
免疫组化, 免疫印迹
反应物种 :
人类, 小鼠, 大鼠
图像标记 :
Anti- p73 antibody, PB9235, Western blotting. All lanes: Anti p73 (PB9235) at 0.5ug/ml. WB: Recombinant Human p73 Protein 0.5ng. Predicted bind size: 45KD. Observed bind size: 45KD Anti- p73 antibody, PB9235, Western blotting. All lanes: Anti p73 (PB9235) at 0.5ug/ml. Lane 1: HELA Whole Cell Lysate at 40ug. Lane 2: MCF-7 Whole Cell Lysate at 40ug. Lane 3: COLO320 Whole Cell Lysate at 40ug. Predicted bind size: 73KD. Observed bind size: 73KD Anti- p73 antibody, PB9235, IHC(P). IHC(P): Human Intestinal Cancer Tissue Anti- p73 antibody, PB9235, IHC(P). IHC(P): Rat Brain Tissue Anti- p73 antibody, PB9235, IHC(P). IHC(P): Mouse Intestine Tissue
背景 :
p73, also known as tumor protein 73(TP73), encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It is mapped to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Furthermore, recent finding are suggesting that over-expression of transcription factors involved in cell cycle regulation and synthesis of DNA in mammalian cells (e.g.: E2F-1) induces the expression of p73. In addition, p73 is a substrate of the c-Abl kinase and that the ability of c-Abl to phosphorylate p73 is markedly increased by gamma-irradiation.
competitor equivalent skus :
sc 101769 sc 17823 sc 23429 sc 244651 sc 247261 sc 247262 sc 56086 sc 56190 sc 56191 sc 56194 sc 70966 sc 7236 sc 7237 sc 7238 sc 7957 sc 7957 X sc 9651
研究种类 :
Apoptosis, Cell Biology, Intracellular, P53 Pathway
同义词 :
Tumor protein p73;p53-like transcription factor;p53-related protein;TP73;P73;
基因全称 :
肿瘤蛋白p73
分子量 :
69623分子量
protein function :
Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
subcellular localization :
Nucleus . Cytoplasm. Accumulates in the nucleus in response to DNA damage.
组织特异性 :
Expressed in striatal neurons of patients with Huntington disease (at protein level). Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue.
蛋白名 :
肿瘤蛋白p73
recommended detection systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
sequence similarities :
Belongs to the p53 family.
更新 :
1/28/19 19:39
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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