产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
Anti-PP2A-alpha/PPP2CA Picoband Antibody
目录 :
PB9347
规格 :
100 ug/vial
价格 :
280美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化
图像
图像 1 :
武汉博士德生物工程有限公司 PB9347 图像 1
Anti- PP2A-alpha Picoband antibody, PB9347, Western blotting. All lanes: Anti PP2A-alpha (PB9347) at 0.5ug/ml. Lane 1: Rat Kidney Tissue Lysate at 50ug. Lane 2: Mouse Kidney Tissue Lysate at 50ug. Lane 3: Human Placenta Tissue Lysate at 50ug. Lane 4: Rat Liver Tissue Lysate at 50ug. Lane 5: NIH Whole Cell Lysate at 40ug. Lane 6: PC-12 Whole Cell Lysate at 40ug. Lane 7: 293T Whole Cell Lysate at 40ug. Predicted bind size: 36KD. Observed bind size: 36KD
图像 2 :
武汉博士德生物工程有限公司 PB9347 图像 2
Anti- PP2A-alpha Picoband antibody, PB9347, IHC(P). IHC(P): Mouse Brain Tissue
图像 3 :
武汉博士德生物工程有限公司 PB9347 图像 3
Anti- PP2A-alpha Picoband antibody, PB9347, IHC(P). IHC(P): Rat Brain Tissue
产品信息
SKU号 :
PB9347
状态 :
Enabled
名称 :
Anti-PP2A-alpha/PPP2CA Picoband Antibody
目录名称 :
一抗, 多克隆抗体, 免疫组化免疫细胞化学IF抗体
基因名称 :
PPP2CA
价格 :
280美元
price various sizes :
Unconjugated / $280 APC / $330 APC-Cy7 / $330 FITC / $330 PE / $330 PE-Cy5 / $330 PE-Cy7 / $330 30ug sample size / $99 100ug / $280 100ug+Free HRP Secondary BA1054 / $280 100ug+Free Biotin Secondary BA1003 / $280
克隆性 :
多克隆
浓度 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
共轭标签 :
No
contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
描述 :
Polyclonal antibody for PP2A ALPHA/PPP2CA detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IHC-P. Reactive species: Human. PP2A ALPHA/PPP2CA information: Molecular Weight: 35594 MW; Subcellular Localization: Cytoplasm . Nucleus . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle pole . In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles. Centromeric localization requires the presence of SGOL2 (By similarity).
short description :
Rabbit IgG polyclonal antibody for Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform(PPP2CA) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
规格 :
100 ug/vial
sample size available :
30ug for $99, contact us for details
UniProt数据库编号 :
P67775
宿主 :
免疫原 :
E.coli-derived human PP2A-alpha recombinant protein (Position: M1-L309). Human PP2A-alpha shares 100% amino acid (aa) sequence identity with both mouse and rat PP2A-alpha.
形式 :
冻干
纯化 :
免疫原亲和纯化
储存 :
At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.
交叉活性 :
PP2A-alpha shares 100% cross reactivity with PPP2CB.
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
应用细节 :
Immunohistochemistry(Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat. Western blot, 0.1-0.5ug/ml, Human, Mouse, Rat.
应用 :
免疫组化, 免疫印迹
反应物种 :
人类, 小鼠, 大鼠
前体活性 :
图像标记 :
Anti- PP2A-alpha Picoband antibody, PB9347, Western blotting. All lanes: Anti PP2A-alpha (PB9347) at 0.5ug/ml. Lane 1: Rat Kidney Tissue Lysate at 50ug. Lane 2: Mouse Kidney Tissue Lysate at 50ug. Lane 3: Human Placenta Tissue Lysate at 50ug. Lane 4: Rat Liver Tissue Lysate at 50ug. Lane 5: NIH Whole Cell Lysate at 40ug. Lane 6: PC-12 Whole Cell Lysate at 40ug. Lane 7: 293T Whole Cell Lysate at 40ug. Predicted bind size: 36KD. Observed bind size: 36KD Anti- PP2A-alpha Picoband antibody, PB9347, IHC(P). IHC(P): Mouse Brain Tissue Anti- PP2A-alpha Picoband antibody, PB9347, IHC(P). IHC(P): Rat Brain Tissue Anti- PP2A-alpha Picoband antibody, PB9347, IHC(P). IHC(P): Human Lung Cancer Tissue
背景 :
The catalytic subunit of human protein phosphatase 2A (PPP2CA) encodes a 309-amino acid polypeptide. It is localized to chromosome 5. The gene (approximately 30 kbp) is composed of seven exons and six introns. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue (Leu309) of protein serine/threonine phosphatase 2A catalytic subunit (PP2AC) is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.
competitor equivalent skus :
sc 50736 sc 50733 sc 390339 sc 366111 sc 81286 sc 390138
研究种类 :
Epigenetics And Nuclear Signaling, Intracellular Signaling, Kinases/Phosphatases, Neuroscience, Neurotransmission, Protein Phosphorylation, Ser / Thr Phosphatases, Signal Transduction, Signaling Pathways, Stem Cells, Tgf Beta
同义词 :
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform;PP2A-alpha;3.1.3.16;Replication protein C;RP-C;PPP2CA;
基因全称 :
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
分子量 :
35594分子量
protein function :
PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
subcellular localization :
Cytoplasm . Nucleus . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle pole . In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles. Centromeric localization requires the presence of SGOL2 (By similarity).
蛋白名 :
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
recommended detection systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
更新 :
1/28/19 19:39
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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