产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
Anti-Peroxiredoxin 1/PRDX1 Picoband Antibody
目录 :
PB9348
规格 :
100 ug/vial
价格 :
280美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学
图像
图像 1 :
武汉博士德生物工程有限公司 PB9348 图像 1
Anti- Peroxiredoxin 1 Picoband antibody, PB9348, Western blotting. All lanes: Anti Peroxiredoxin 1 (PB9348) at 0.5ug/ml. Lane 1: Rat Brain Tissue Lysate at 50ug. Lane 2: Mouse Brain Tissue Lysate at 50ug. Lane 3: U87 Whole Cell Lysate at 40ug. Lane 4: NEURO Whole Cell Lysate at 40ug. Lane 5: A375 Whole Cell Lysate at 40ug. Lane 6: 293T Whole Cell Lysate at 40ug. Lane 7: SMMC Whole Cell Lysate at 40ug. Lane 8: A549 Whole Cell Lysate at 40ug. Lane 9: RH35 Whole Cell Lysate at 40ug. Predicted bind size: 22KD. Observed bind size: 22KD
图像 2 :
武汉博士德生物工程有限公司 PB9348 图像 2
Anti- Peroxiredoxin 1 Picoband antibody, PB9348, IHC(P). IHC(P): Mouse Brain Tissue
图像 3 :
武汉博士德生物工程有限公司 PB9348 图像 3
Anti- Peroxiredoxin 1 Picoband antibody, PB9348, IHC(P). IHC(P): Rat Brain Tissue
产品信息
SKU号 :
PB9348
状态 :
Enabled
名称 :
Anti-Peroxiredoxin 1/PRDX1 Picoband Antibody
目录名称 :
一抗, 多克隆抗体, 免疫组化免疫细胞化学IF抗体
基因名称 :
PRDX1
价格 :
280美元
price various sizes :
Unconjugated / $280 APC / $330 APC-Cy7 / $330 FITC / $330 PE / $330 PE-Cy5 / $330 PE-Cy7 / $330 30ug sample size / $99 100ug / $280 100ug+Free HRP Secondary BA1054 / $280 100ug+Free Biotin Secondary BA1003 / $280
克隆性 :
多克隆
浓度 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
共轭标签 :
No
contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
描述 :
Polyclonal antibody for Peroxiredoxin 1/PRDX1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IHC-P. Reactive species: Human. Peroxiredoxin 1/PRDX1 information: Molecular Weight: 22110 MW; Subcellular Localization: Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
short description :
Rabbit IgG polyclonal antibody for Peroxiredoxin-1(PRDX1) detection. Tested with WB, IHC-P, ICC in Human;Mouse;Rat.
规格 :
100 ug/vial
sample size available :
30ug for $99, contact us for details
UniProt数据库编号 :
Q06830
宿主 :
免疫原 :
A synthetic peptide corresponding to a sequence in the middle region of human Peroxiredoxin 1 (100-128aa MNIPLVSDPKRTIAQDYGVLKADEGISFR), different from the related mouse sequence by one amino acid, and identical to the related rat sequence.
形式 :
冻干
纯化 :
免疫原亲和纯化
储存 :
At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.
交叉活性 :
No cross reactivity with other proteins.
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
应用细节 :
Immunocytochemistry , 0.5-1ug/ml, Human, -. Immunohistochemistry(Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat. Western blot, 0.1-0.5ug/ml, Human, Mouse, Rat.
应用 :
免疫组化, 免疫细胞化学, 免疫印迹
反应物种 :
人类, 小鼠, 大鼠
前体活性 :
仓鼠
图像标记 :
Anti- Peroxiredoxin 1 Picoband antibody, PB9348, Western blotting. All lanes: Anti Peroxiredoxin 1 (PB9348) at 0.5ug/ml. Lane 1: Rat Brain Tissue Lysate at 50ug. Lane 2: Mouse Brain Tissue Lysate at 50ug. Lane 3: U87 Whole Cell Lysate at 40ug. Lane 4: NEURO Whole Cell Lysate at 40ug. Lane 5: A375 Whole Cell Lysate at 40ug. Lane 6: 293T Whole Cell Lysate at 40ug. Lane 7: SMMC Whole Cell Lysate at 40ug. Lane 8: A549 Whole Cell Lysate at 40ug. Lane 9: RH35 Whole Cell Lysate at 40ug. Predicted bind size: 22KD. Observed bind size: 22KD Anti- Peroxiredoxin 1 Picoband antibody, PB9348, IHC(P). IHC(P): Mouse Brain Tissue Anti- Peroxiredoxin 1 Picoband antibody, PB9348, IHC(P). IHC(P): Rat Brain Tissue Anti- Peroxiredoxin 1 Picoband antibody, PB9348, IHC(P). IHC(P): Huma Mammary Cancer Tissue Anti- Peroxiredoxin 1 Picoband antibody, PB9348, ICC. ICC: SMMC-7721 Cell
背景 :
PRDX1(Peroxiredoxin 1), also called PRX1, PAGA or NKEFA, is a thiol reductase that plays critical roles in oxidative and thermal stress defense mechanisms through its abilities to metabolize H2O2 and act as a molecular chaperone, respectively. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The PRDX1 gene is mapped on 1p34.1. Prdx1 was expressed in differentiating motor neuron cells in developing embryonic chicken and mouse spinal cords. mmunoprecipitation analysis showed that GDE2 interacted directly with PRDX1 in embryonic chicken spinal cord extracts and in transfected HEK293T cells. This protein may have a proliferative effect and play a role in cancer development or progression. In differentiating spinal cord, Prdx1 was required to activate Gde2 by reducing an intramolecular cystine bridge between the Gde2 N- and C-terminal domains. An intramolecular disulfide bond between the GDE2 N- and C-terminal domains inhibits GDE2 function, and that reduction of this cystine by PRDX1 activates GDE2 for the induction of motor neuron differentiation.
competitor equivalent skus :
sc 292260 sc 374247 sc 5382 sc 5380 sc 166564 sc 292260 X sc 374247 X sc 5382 X sc 5380 X sc 166564 X
研究种类 :
Atherosclerosis, Cardiovascular, Cell Biology, Metabolism, Oxidative Stress, Pathways And Processes, Redox Metabolism, Vascular Inflammation
同义词 :
Peroxiredoxin-1;1.11.1.15;Natural killer cell-enhancing factor A;NKEF-A;Proliferation-associated gene protein;PAG;Thioredoxin peroxidase 2;Thioredoxin-dependent peroxide reductase 2;PRDX1;PAGA, PAGB, TDPX2;
基因全称 :
过氧化还原酶1
分子量 :
22110分子量
protein function :
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).
subcellular localization :
Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
蛋白名 :
过氧化还原酶1
recommended detection systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P) and ICC.
sequence similarities :
Belongs to the AhpC/TSA family.
更新 :
1/28/19 19:39
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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