产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
Anti-BMP2 Picoband Antibody
目录 :
PB9687
规格 :
100 ug/vial
价格 :
280美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化
图像
图像 1 :
武汉博士德生物工程有限公司 PB9687 图像 1
Anti- BMP-2 Picoband antibody, PB9687, Western blotting. All lanes: Anti BMP-2 (PB9687) at 0.5ug/ml. Lane 1: Rat Lung Tissue Lysate at 50ug. Lane 2: Rat Brain Tissue Lysate at 50ug. Lane 3: U87 Whole Cell Lysate at 40ug. Lane 4: HELA Whole Cell Lysate at 40ug. Predicted bind size: 45KD. Observed bind size: 20 KD, 40KD
图像 2 :
武汉博士德生物工程有限公司 PB9687 图像 2
Anti- BMP-2 Picoband antibody, PB9687, IHC(P). IHC(P): Human Intestinal Cancer Tissue
产品信息
SKU号 :
PB9687
状态 :
Enabled
名称 :
Anti-BMP2 Picoband Antibody
目录名称 :
一抗, 多克隆抗体, 免疫组化免疫细胞化学IF抗体
基因名称 :
骨形态发生蛋白2
价格 :
280美元
price various sizes :
Unconjugated / $280 APC / $330 APC-Cy7 / $330 FITC / $330 PE / $330 PE-Cy5 / $330 PE-Cy7 / $330 30ug sample size / $99 100ug / $280 100ug+Free HRP Secondary BA1054 / $280 100ug+Free Biotin Secondary BA1003 / $280
克隆性 :
多克隆
浓度 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
共轭标签 :
No
contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
描述 :
Polyclonal antibody for BMP 2/BMP2 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: ELISA. Reactive species: Human. BMP 2/BMP2 information: Molecular Weight: 44702 MW; Subcellular Localization: Secreted; Tissue Specificity: Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
short description :
Rabbit IgG polyclonal antibody for Bone morphogenetic protein 2(BMP2) detection. Tested with WB, IHC-P, ELISA in Human;Rat.
规格 :
100 ug/vial
sample size available :
30ug for $99, contact us for details
UniProt数据库编号 :
P12643
宿主 :
免疫原 :
A synthetic peptide corresponding to a sequence at the C-terminus of human BMP-2 (283-312aa QAKHKQRKRLKSSCKRHPLYVDFSDVGWND), identical to the related mouse and rat sequences.
形式 :
冻干
纯化 :
免疫原亲和纯化
储存 :
At -20 C for one year. After reconstitution, at 4 C for one month. It can also be aliquotted and stored frozen at -20 C for a longer time.Avoid repeated freezing and thawing.
交叉活性 :
No cross reactivity with other proteins
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
应用细节 :
Immunohistochemistry(Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat . ELISA , 0.1-0.5ug/ml, Human, -. Western blot, 0.1-0.5ug/ml, Human, Rat.
应用 :
酶联免疫吸附测定, 免疫组化, 免疫印迹
反应物种 :
人类, 大鼠
前体活性 :
仓鼠
图像标记 :
Anti- BMP-2 Picoband antibody, PB9687, Western blotting. All lanes: Anti BMP-2 (PB9687) at 0.5ug/ml. Lane 1: Rat Lung Tissue Lysate at 50ug. Lane 2: Rat Brain Tissue Lysate at 50ug. Lane 3: U87 Whole Cell Lysate at 40ug. Lane 4: HELA Whole Cell Lysate at 40ug. Predicted bind size: 45KD. Observed bind size: 20 KD, 40KD Anti- BMP-2 Picoband antibody, PB9687, IHC(P). IHC(P): Human Intestinal Cancer Tissue
背景 :
BMP2 is also known as Bone morphogenetic protein 2 or BMP2A. It is mapped to 20p12. The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. BMP-2, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. It is involved in the hedgehog pathway, TGF beta signaling pathway, and in cytokine-cytokine receptor interaction. Also, it is involved in cardiac cell differentiation and epithelial to mesenchymal transition. In addition, BMP2A has been suggested as a reasonable candidate for the human condition fibrodysplasia (myositis) ossificans progressiva, on the basis of observations in a Drosophila model.
competitor equivalent skus :
sc 139569 sc 139571 sc 390712
研究种类 :
Neural Stem Cells, Secreted, Signal Transduction, Signaling Pathways, Stem Cells, Structures, Tgf Beta
同义词 :
骨形态发生蛋白2;BMP-2;骨形态发生蛋白2A;BMP-2A;骨形态发生蛋白2;BMP2A;
基因全称 :
骨形态发生蛋白2
分子量 :
44702分子量
protein function :
Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).
subcellular localization :
Secreted.
组织特异性 :
Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
蛋白名 :
骨形态发生蛋白2
recommended detection systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
更新 :
1/28/19 19:39
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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