产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
Anti-BMP4 Antibody Picoband™
目录 :
PB9688
规格 :
100μg/vial
价格 :
315美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定
图像
图像 1 :
武汉博士德生物工程有限公司 PB9688 图像 1
Anti- BMP-4 Picoband antibody, PB9688, Western blotting. All lanes: Anti BMP-4 (PB9688) at 0.5ug/ml. Lane 1: Mouse Lung Tissue Lysate at 50ug. Lane 2: Mouse Liver Tissue Lysate at 50ug. Lane 3: HEPA Whole Cell Lysate at 40ug. Lane 4: HEPG2 Whole Cell Lysate at 40ug. Lane 5: HELA Whole Cell Lysate at 40ug. Predicted bind size: 46KD. Observed bind size: 46KD
产品信息
SKU号 :
PB9688
产品名称 :
Anti-BMP4 Antibody Picoband™
价格 :
315美元
规格 :
100μg/vial
克隆性 :
多克隆
宿主 :
反应物种 :
人类, 小鼠
前体活性 :
应用(s) :
酶联免疫吸附测定, 免疫印迹
应用细节 :
酶联免疫吸附测定, 0.1 0.5µg/毫升, 人类, 小鼠免疫印迹, 0.1 0.5µg/毫升, 人类, 小鼠
应用注释 :
Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
描述 :
Boster Bio Anti-BMP4 Antibody Picoband™ catalog # PB9688. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
浓度 :
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
基因名称 :
BMP4
UniProt数据库编号 :
P12644
免疫原 :
A synthetic peptide corresponding to a sequence at the C-terminus of human BMP-4 (293-324aa SPKHHSQRARKKNKNCRRHSLYVDFSDVGWND), different from the related mouse and rat sequences by two amino acids.
形式 :
冻干
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
纯化 :
免疫原亲和纯化
交叉活性 :
No cross reactivity with other proteins
储存 :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
基因全称 :
骨形态发生蛋白4
同义词 :
骨形态发生蛋白4;BMP-4;骨形态发生蛋白2B;BMP-2B;BMP4;BMP2B, DVR4;
蛋白名 :
骨形态发生蛋白4
分子量 :
46555分子量
Protein Function :
Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).
Subcellular Localization :
Secreted, extracellular space, extracellular matrix.
组织特异性 :
Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
背景 :
Bone morphogenetic protein 4 is a protein that in humans is encoded by BMP4 gene. It is found on chromosome 14q22-q23. The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
研究种类 :
Angiogenesis, Cancer, Cardiovascular, Developmental Biology, Growth Factors, Growth Factors/Hormones, Nervous System Development, Organogenesis, Secreted, Signal Transduction, Signaling Pathways, Stem Cells, Tgf Beta
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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