产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
Anti-FCGRT Antibody Picoband™
目录 :
PB9866
规格 :
100μg/vial
价格 :
315美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
图像
图像 1 :
Western blot analysis of FCGRT expression in A549 whole cell lysates (lane 1). FCGRT at 50KD was detected using rabbit anti- FCGRT Antigen Affinity purified polyclonal antibody (Catalog # PB9866) at0.5 ??g/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002).
图像 2 :
FCGRT was detected in paraffin-embedded sections of human lung cancer tissues using rabbit anti- FCGRT Antigen Affinity purified polyclonal antibody (Catalog # PB9866) at 1 ug/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022).
产品信息
SKU号 :
PB9866
产品名称 :
Anti-FCGRT Antibody Picoband™
价格 :
315美元
规格 :
100μg/vial
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类
应用(s) :
免疫组化, 免疫印迹
应用细节 :
Immunohistochemistry (Paraffin-embedded Section), 0.5-1µg/ml, Human, By Heat.
Western blot, 0.1-0.5µg/ml, Human.
应用注释 :
Tested Species: In-house tested species with positive results.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
描述 :
Boster Bio Anti-FCGRT Antibody Picoband™ catalog # PB9866. Tested in IHC, WB applications. This antibody reacts with Human.
浓度 :
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
基因名称 :
FCGRT
UniProt数据库编号 :
P55899
免疫原 :
E. coli-derived human FCGRT recombinant protein (Position: Q56-E291). Human FCGRT shares 70.2% and 68.9% amino acid (aa) sequence identity with mouse and rat FCGRT, respectively.
形式 :
冻干
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
纯化 :
免疫原亲和纯化
交叉活性 :
No cross reactivity with other proteins.
储存 :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
基因全称 :
IgG receptor FcRn large subunit p51
同义词 :
IgG receptor FcRn large subunit p51; FcRn; IgG Fc fragment receptor transporter alpha chain; Neonatal Fc receptor; FCGRT; FCRN;
蛋白名 :
IgG receptor FcRn large subunit p51
分子量 :
39743分子量
Protein Function :
Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus.
Subcellular Localization :
Cell membrane ; Single-pass type I membrane protein.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
背景 :
IgG receptor FcRn large subunit p51 is a protein that in humans is encoded by the FCGRT gene. This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. In addition, it is postulated that long-range cis inactivation of the FCGRT gene is responsible for hypercatabolism of IgG in myotonic dystrophy. The FCGRT gene is closely situated to the DMPK gene, which is mutant in DM.
研究种类 :
Class I, Immunoglobulins, Immunology, Receptors
更多信息或购买 :
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn925.485.4527
公司总部: 美国
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