SNCG伽玛突触核蛋白人类重组蛋白 | 武汉博士德生物工程有限公司 PROTO76070 产品信息

产品简要

公司名称 :

武汉博士德生物工程有限公司

产品类型 :

蛋白

产品名称 :

SNCG伽玛突触核蛋白人类重组蛋白

PROTO76070

规格 :

20微克, 100微克, 1毫克

价格 :

230美元

更多信息或购买 :

武汉博士德生物工程有限公司产品网页

图像

图像 1 :

Recombinant protein fun image

产品信息

SKU号 :

PROTO76070

状态 :

Enabled

名称 :

SNCG伽玛突触核蛋白人类重组蛋白

基因名称 :

SNCG

价格 :

230美元

price various sizes :

Sample: 20ug / $153 Regular: 100ug / $230 Bulk: 1mg / $983

共轭标签 :

contents :

蛋白(1毫克/毫升)含20mM三羟甲基氨基甲烷氯化氢缓冲液(pH值7.5)和0.1M氯化钠

描述 :

g-Synuclein Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 127 amino acids and having a molecular mass of 13,300 Dalton. The protein coding region of g-synuclein was amplified by RT-PCR and cloned into an E.coli expression vector. g-synuclein was overexpressed in E. coli and purified to apparent homogeneity by taking advantage of the thermosolubility of the protein and by using conventional column chromatography techniques.

short description :

g-Synuclein Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 127 amino acids and having a molecular mass of 13,300 Dalton. The protein coding region of g-synuclein was amplified by RT-PCR and cloned into an E.coli expression vector. g-synuclein was overexpressed in E. Coli and purified to apparent homogeneity by taking advantage of the thermosolubility of the protein and by using conventional column chromatography techniques.

description1 :

Introduction . g-synuclein(Originally known as a breast cancer specific gene product, BCSG1) is an acidic neuronal protein of 127 amino acids. Gamma-Synuclein is a member of the Synuclein protein family, which is believed to be involved in the pathogenesis of neurodegenerative diseases. High levels of Gamma-Synuclein have been found in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development. Synuclein-Gamma is found mostly in the peripheral nervous system (in primary sensory neurons, sympathetic neurons, and motor neurons) and retina. SNCG is also identified in the brain, ovarian tumors, and in the olfactory epithelium. SNCG expression in breast tumors is a marker for tumor progression. A modification in the expression of gamma-synuclein has been detected in the retina of Alzheimer's patients.

description2 :

氨基酸序列MDVFKKGFSI AKEGVVGAVE KTKQGVTEAA EKTKEGVMYV GAKTKENVVQSVTSVAEKTK EQANAVSEAV VSSVNTVATK TVEEAENIAV TSGVVRKEDL RPSAPQQEGV ASKEKEEVAE EAQSGGD

规格 :

20微克, 100微克, 1毫克

UniProt数据库编号 :

O76070

宿主 :

形式 :

Sterile filtered colorless solution.

纯化 :

Greater than 95.0% as determined by SDS-PAGE.

储存 :

Store in -20 C for long term storage. After reconstitution, store in 4 C for short term usage within a few days. Avoid freeze-thaw cycles.

应用 :

细胞培养

图像标记 :

Recombinant protein fun image

同义词 :

Gamma-synuclein;Breast cancer-specific gene 1 protein;Persyn;Synoretin;SR;SNCG;BCSG1, PERSYN, PRSN;

基因全称 :

伽玛突触核蛋白

protein function :

Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).

subcellular localization :

Cytoplasm, perinuclear region

组织特异性 :

Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung.

来源 :

大肠杆菌

更新 :

2/18/19 20:29

更多信息或购买 :

武汉博士德生物工程有限公司产品网页

公司信息