蛋白

KLK1激肽释放酶1人类重组蛋白

PROTP06870

20微克, 100微克, 1毫克

250美元

KLK1激肽释放酶1人类重组蛋白

https://www.bosterbio.comklk1-kallikrein-1-human-recombinant-protein-protp06870-boster.html

KLK1

250美元

20微克, 100微克, 1毫克

小鼠

细胞培养

Introduction: Kallikreins are serine protease enzymes having various physiological functions. Kallikreins are implicated in carcinogenesis and have potenital as novel cancer disease biomarkers. KLKthe fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLKbradykininogen to bradykinin. Kallikrein-1, which derived from human or porcine, have been used as drugs for a long time, they are mainly used in the treatment f light to medium hypertension and occlusion of cerebral and surrounding blood vessels. KLKhuman umbilical veins. The K allele of KLKTGF-betaKLKKLK1on the surface which is important function in maintenance of circulation homeostasis. KLKdesmoglein 1 and regulation by lympho-epithelial Kazal-type-related inhibitor (LEKTI).

KLK1 Human Recombinant produced in Yeast is a single, glycosylated, polypeptide chain containing 238 amino acids and having a molecular mass of 28-32 kDa. KLK1 Human Recombinant is purified by proprietary chromatographic techniques.

Pichia Pastoris.

Sterile Filtered white lyophilized powder.

冻干来自a溶液含1xPBS

Amino Acid Sequence: The sequence of the first five N-terminal amino acids was determined and was found to be Ile-Val-Gly-Gly-Trp-Glu.

Greater than 98.0% as determined by both: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Store KLK1 at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.

P06870

激肽释放酶1

激肽释放酶1;3.4。 21.35;肾脏/胰腺/唾腺激肽释放酶;组织激肽释放酶;KLK1;

Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.

Isoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84.