GRO甲大鼠重组蛋白(CXCL1) | 武汉博士德生物工程有限公司 PROTP14095 产品信息

产品简要

公司名称 :

武汉博士德生物工程有限公司

产品类型 :

蛋白

产品名称 :

GRO甲大鼠重组蛋白(CXCL1)

PROTP14095

规格 :

5微克, 25微克, 1毫克

价格 :

250美元

更多信息或购买 :

武汉博士德生物工程有限公司产品网页

产品信息

SKU号 :

PROTP14095

产品名称 :

GRO甲大鼠重组蛋白(CXCL1)

产品网站地址 :

https://www.bosterbio.comgro-alpha-rat-recombinant-protein-cxcl1-protp14095-boster.html

基因名称 :

Cxcl1

价格 :

250美元

规格 :

5微克, 25微克, 1毫克

反应物种 :

小鼠

应用 :

细胞培养

Introduction :

Introduction: Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-?). It is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines.

描述 :

CXCL1 Rat Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7.8 kDa. The Rat CXCL1 is purified by proprietary chromatographic techniques.

来源 :

大肠杆菌

形式 :

Sterile Filtered White lyophilized (freeze-dried) powder.

Contents :

Lyophilized from a 0.2?m filtered concentrated (1mg/ml) solution in 20mM PB, pH 7.4, and 150mM NaCl.

氨基酸序列和/或生物活性 :

Amino Acid Sequence: APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK. Biological Activity: Determined by its ability to chemoattract rat neutrophils using a concentration range of 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

纯化 :

Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

储存 :

Lyophilized CXCL1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

UniProt数据库编号 :

P14095

基因全称 :

Growth-regulated alpha protein

同义词 :

Growth-regulated alpha protein;C-X-C motif chemokine 1;Cytokine-induced neutrophil chemoattractant 1;CINC-1;Platelet-derived growth factor-inducible protein KC;Cxcl1;Cinc1, Gro, Scyb1;

Protein Function :

Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation.

Subcellular Localization :

Secreted.

组织特异性 :

At least expressed in the lung and trachea.

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公司信息