产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
蛋白
产品名称 :
重组小鼠肿瘤坏死因子甲蛋白
目录 :
R00002-1
规格 :
100µg/vial
价格 :
240美元
产品信息
SKU号 :
R00002-1
产品名称 :
重组小鼠肿瘤坏死因子甲蛋白
产品网站地址 :
https://www.bosterbio.comrecombinant-mouse-tnf-alpha-protein-r00002-1-boster.html
基因名称 :
肿瘤坏死因子
价格 :
240美元
规格 :
100µg/vial
反应物种 :
小鼠
描述 :
Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved insystemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocyts, NK cells, neutrophils, mast cells, eosinophils, and neurons. The primary role of TNF is in the regulation of immune cells. TNF, being an endogenous pyrogen, is able to induce fever, apoptotic cell death, cachexia, inflammation and to inhibit tumorigenesis andviral replicatin and respond to sepsis via IL1 & IL6 producing cells. Dysregulation of TNF production has been implicated in a variety of human diseases including Alzheimer's disease, cancer, major depression, psoriasisand inflammatory bowel disease (IBD).Though controversial, studies of depression and IBD are currentlybeing linked to TNF levels. Recombinant TNF is used as an immunostimulant under the INN tasonermin. TNF can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
来源 :
大肠杆菌L81-L235
形式 :
冻干
Contents :
Lyophilized after extensive dialysis against PBS.
氨基酸序列和/或生物活性 :
Amino Acid Sequence: LRSSS QNSSD KPVAH VVANH QVEEQ LEWLS QRANA LLANG MDLKD NQLVV PADGL YLVYS QVLFK GQGCP DYVLL THTVS RFAIS YQEKV NLLSA VKSPC PKDTP EGAEL KPWYE PIYLG GVFQL EKGDQ LSAEV NLPKY LDFAE SGQVY FGVIA L
纯化 :
>95%, by SDS-PAGE quantitative densitometry by Coomassie® Blue Staining.
储存 :
Lyophilized recombinant mouse TNF alpha remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmTNF alpha remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.
UniProt数据库编号 :
P06804
分子量 :
17.2KD
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
Premium Provider of Antibodies and ELISA Kits