抗体

抗MUC2抗体;抗AAMP抗体

RP1038

100 ug/vial; 100 ug/vial

200美元

多克隆

兔

nonconjugated

人类, 小鼠, 大鼠

免疫印迹, 免疫组化-石蜡切片

抗MUC2抗体;抗AAMP抗体

200美元

E.coli-derived human MUC2 recombinant protein (Position: S21-W380). Human MUC2 shares 78% and 79% amino acid (aa) sequences identity with mouse and rat MUC2, respectively.; E.coli-derived human AAMP recombinant protein (Position: E235-R434).

冻干;冻干

兔;兔

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.; Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

免疫原亲和纯化.;免疫原亲和纯化

多克隆

Rabbit IgG polyclonal antibody for Mucin-2(MUC2) detection. Tested with IHC-P in Human;Mouse;Rat.; Rabbit IgG polyclonal antibody for Angio-associated migratory cell protein(AAMP) detection. Tested with WB, IHC-P in Human.

100 ug/vial; 100 ug/vial

人类;小鼠;大鼠;人类

免疫组化-P;免疫组化-P;免疫印迹

Mucin 2, also known as MUC2, is a protein that in humans is encoded by the MUC2 gene. This gene encodes a member of the mucin protein family. It is mapped to 11p15.5. Mucin 2 is particularly prominent in the gut where it is secreted from goblet cells in the epithelial lining into the lumen of the large intestine. There, mucin 2, along with small amounts of related-mucin proteins, polymerizes into a gel of which 80% by weight is oligosaccharide side-chains that are added as post-translational modifications to the mucin proteins. This gel provides an insoluble mucous barrier that serves to protect the intestinal epithelium. The primary function of the MUC2 gene product is to provide a protective barrier between the epithelial surfaces and the gut lumen. There is decreased expression of MUC2 in colonic cancer and defective polymerization of secreted mucin in ulcerative colitis. ; AAMP, also known as Angio-associated, migratory cell protein, is a protein which in humans is encoded by the AAMP gene. It is mapped to 2q35. The gene product of AAMP is an immunoglobulin-type protein, which is found to be expressed strongly in endothelial cells, cytotrophoblasts, and poorly differentiated colon adenocarcinoma cells found in lymphatics. It has been demonstrated that an AAMP peptide containing the putative heparan sulfate-binding domain binds to heparin and mediates heparin-sensitive cell adhesion. AAMP plays a role in angiogenesis and cell migration. In smooth muscle cell migration, it may act through the RhoA pathway.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.; Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

No cross reactivity with other proteins; No cross reactivity with other proteins.

Mucin-2; angio-associated, migratory cell protein

MUC2;AAMP

Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.

Mucin-2; Angio-associated migratory cell protein

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

tags & cell markers cell type markers tumor associated signal transduction cytoskeleton / ecm extracellular matrix ecm proteins muc cancer invasion/microenvironment tumor immunology tumor-associated antigens

At -20ËšC for one year. After reconstitution, at 4ËšC for one month. It can also be aliquotted and stored frozen at -20ËšC for a longer time.Avoid repeated freezing and thawing. ; At -20ËšC for one year. After reconstitution, at 4ËšC for one month. It can also be aliquotted and stored frozen at -20ËšC for a longer time.Avoid repeated freezing and thawing.

Secreted. In the intestine, secreted into the inner and outer mucus layers.

Mucin-2;MUC-2;Intestinal mucin-2;MUC2;SMUC;; AAMP antibody Angio associated migratory cell protein antibody

Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.

Q02817;Q13685