产品简要
公司名称 :
武汉博士德生物工程有限公司
产品类型 :
抗体
产品名称 :
抗水闸蛋白5/CLDN5抗体
目录 :
RP1043
规格 :
100μg/vial
价格 :
315美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 大鼠
应用 :
免疫印迹
图像
图像 1 :
武汉博士德生物工程有限公司 RP1043 图像 1
Anti- Claudin 5 Picoband antibody, RP1043, Western blotting. All lanes: Anti Claudin-5 (RP1043) at 0.5ug/ml. WB: Rat Liver Tissue Lysate at 50ug. Predicted bind size: 23KD. Observed bind size: 23KD
产品信息
SKU号 :
RP1043
产品名称 :
抗水闸蛋白5/CLDN5抗体
价格 :
315美元
规格 :
100μg/vial
克隆性 :
多克隆
宿主 :
反应物种 :
人类, 大鼠
应用(s) :
免疫印迹
应用细节 :
免疫印迹, 0.1 0.5µg/毫升, 大鼠, 人类
应用注释 :
WB: The detection limit for Claudin 5 is approximately 0.2ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
描述 :
Boster Bio Anti-Claudin 5/CLDN5 Antibody catalog # RP1043. Tested in WB applications. This antibody reacts with Human, Rat.
浓度 :
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
基因名称 :
CLDN5
UniProt数据库编号 :
O00501
免疫原 :
A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 5 (191-218aa RPDLSFPVKYSAPRRPTATGDYDKKNYV), different from the related mouse sequence by three amino acids and from the related rat sequence by four amino acids.
形式 :
冻干
Contents :
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg NaN 3 .
纯化 :
免疫原亲和纯化
交叉活性 :
No cross reactivity with other proteins
储存 :
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
重组 :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
基因全称 :
水闸蛋白5
同义词 :
Claudin-5; Transmembrane protein deleted in VCFS; TMDVCF; CLDN5; AWAL, TMVCF;
蛋白名 :
水闸蛋白5
分子量 :
23147分子量
Protein Function :
Plays a major role in tight junction-specific obliteration of the intercellular space.
Subcellular Localization :
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
背景 :
Claudin-5 (CLDN5) also known as BEC1, is a protein that in humans is encoded by the CLDN5 gene. By use of yeast artificial chromosomes, Claudin-5 is localized between polymorphic markers D22S944 and D22S941 on chromosome 22q11, both of which are deleted in more than 80% of VCFS patients. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. What's more, it plays a major role in tight junction-specific obliteration of the intercellular space.
研究种类 :
Cell Adhesion, Cytoskeleton / Ecm, Signal Transduction, Tight Junctions
公司信息
武汉博士德生物工程有限公司
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
http://www.boster.com.cn
925.485.4527
公司总部: 美国
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