蛋白

PODS™人类TGF-β1

PPH39-50

50 million

145美元

PODS™人类TGF-β1

生长因子

50 million

145美元

TransforminG Growth Factor beta 1 (TGF-β1) is a member of the TGF-β superfamily of cytokines. Members of this family exhibit reGulatory activity in immunity, proliferation, adhesion, miGration, and Growth inhibition pathways. TGF-β1 siGnals throuGh SMAD proteins via the TGF-β RI and TGF-β RII receptors.

人类

PODS™ crystals provide a depot of proteins which are steadily secreted. It has been estimated that the biolo gical activity of 50 million PODS™ crystals generates the same peak dose as 3.3 μ g of standard recombinant protein. However, at 5 days followin g the start of seedin g the PODS™ crystals, there are more than 50% of these peak levels still present in the culture system. Ultimately, the amount of PODS™ crystals that is optimal for a particular experiment should be determined empirically. Based on previous data, we su g gest usin g 50 million PODS™ crystals in place of 3.3 μ g of standard growth factor as a startin g point." To control for cross-reactivity with cells or as a ne gative control, we recommend usin g PODS™ growth factors alon gside PODS™ Empty crystals, as the latter do not contain or release car go protein. AA Sequence

Upon receipt, store at 4°C. PODS™ protein crystals are stable for at least 1 year when dry and 6 months when resuspended.