产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Cox2(D5H5)XP®兔单克隆抗体
目录 :
12282
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D5H5
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片
文章摘录数: 44
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1000; 图 2b
Parodi B, Sanna A, Cedola A, Uccelli A, Kerlero de Rosbo N. Hydroxycarboxylic Acid Receptor 2, a Pleiotropically Linked Receptor for the Multiple Sclerosis Drug, Monomethyl Fumarate. Possible Implications for the Inflammatory Response. Front Immunol. 2021;12:655212 pubmed 出版商
  • 免疫组化; 人类; 1:600; 图 4a
Zimmer T, Broekaart D, Luinenburg M, Mijnsbergen C, Anink J, Sim N, et al. Balloon cells promote immune system activation in focal cortical dysplasia type 2b. Neuropathol Appl Neurobiol. 2021;47:826-839 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Jindal S, Pennock N, Klug A, Narasimhan J, Calhoun A, Roberts M, et al. S-nitrosylated and non-nitrosylated COX2 have differential expression and distinct subcellular localization in normal and breast cancer tissue. NPJ Breast Cancer. 2020;6:62 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 s10b
Kim H, Hwang S, Sung B, Kim Y, Chang Y. Gd-Complex of a Rosmarinic Acid Conjugate as an Anti-Inflammatory Theranostic Agent via Reactive Oxygen Species Scavenging. Antioxidants (Basel). 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 9b
Kong Y, Xu S. Juglanin administration protects skin against UVB‑induced injury by reducing Nrf2‑dependent ROS generation. Int J Mol Med. 2020;46:67-82 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 图 3e
Fong L, Taccioli C, Palamarchuk A, Tagliazucchi G, Jing R, Smalley K, et al. Abrogation of esophageal carcinoma development in miR-31 knockout rats. Proc Natl Acad Sci U S A. 2020;117:6075-6085 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 图 11b
  • 免疫印迹; 大鼠; 1:1000; 图 8a
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1b
Jiang L, Xu K, Li J, Zhou X, Xu L, Wu Z, et al. Nesfatin-1 suppresses interleukin-1β-induced inflammation, apoptosis, and cartilage matrix destruction in chondrocytes and ameliorates osteoarthritis in rats. Aging (Albany NY). 2020;12:1760-1777 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4b
Wang X, Chang Y, He Y, Lyu C, Li H, Zhu J, et al. Glimepiride and glibenclamide have comparable efficacy in treating acute ischemic stroke in mice. Neuropharmacology. 2020;162:107845 pubmed 出版商
  • 免疫印迹; 大鼠; 图 2d
Huang X, Ni B, Xi Y, Chu X, Zhang R, You H. Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis. Aging (Albany NY). 2019;11:12532-12545 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 7e
Roy N, Monisha J, Padmavathi G, Lalhruaitluanga H, Kumar N, Singh A, et al. Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma. Biomolecules. 2019;9: pubmed 出版商
  • 免疫印迹; 小鼠; 图 6b
Feng F, Wang Z, Li R, Wu Q, Gu C, Xu Y, et al. Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2. Biomed Pharmacother. 2019;112:108669 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 5d
Zhang P, Bi R, Gan Y. Glial interleukin-1β upregulates neuronal sodium channel 1.7 in trigeminal ganglion contributing to temporomandibular joint inflammatory hypernociception in rats. J Neuroinflammation. 2018;15:117 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 8
Wang X, Shaw D, Hammond H, Sutterwala F, Rayamajhi M, Shirey K, et al. The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation. PLoS Pathog. 2016;12:e1005803 pubmed 出版商
  • 免疫组化; 人类; 图 4a
Lin A, Wang G, Zhao H, Zhang Y, Han Q, Zhang C, et al. TLR4 signaling promotes a COX-2/PGE2/STAT3 positive feedback loop in hepatocellular carcinoma (HCC) cells. Oncoimmunology. 2016;5:e1074376 pubmed
  • 免疫印迹; 人类; 图 4c
Li J, Tang C, Li L, Li R, Fan Y. Quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo. J Exp Clin Cancer Res. 2016;35:61 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Ding X, Pan L, Wang Y, Xu Q. Baicalin exerts protective effects against lipopolysaccharide-induced acute lung injury by regulating the crosstalk between the CX3CL1-CX3CR1 axis and NF-κB pathway in CX3CL1-knockout mice. Int J Mol Med. 2016;37:703-15 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500; 图 1
Radhika N, Govindaraj V, Sarangi S, Rao A. Neonatal exposure to 17β-estradiol down-regulates the expression of synaptogenesis related genes in selected brain regions of adult female rats. Life Sci. 2015;141:1-7 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7c
Bugajev V, Hálová I, Dráberová L, Bambousková M, Potůčková L, Draberova H, et al. Negative regulatory roles of ORMDL3 in the FcεRI-triggered expression of proinflammatory mediators and chemotactic response in murine mast cells. Cell Mol Life Sci. 2016;73:1265-85 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6b
  • 免疫组化-石蜡切片; 人类; 图 6a
  • 免疫印迹; 人类; 1:1000; 图 s4i
SCANLON C, Banerjee R, Inglehart R, Liu M, Russo N, Hariharan A, et al. Galanin modulates the neural niche to favour perineural invasion in head and neck cancer. Nat Commun. 2015;6:6885 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Lin X, Xu W, Shao M, Fan Q, Wen G, Li C, et al. Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration. BMC Complement Altern Med. 2015;15:126 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6
Lee S, Chang J, Wu J, Sheu D. Antineoplastic effect of a novel chemopreventive agent, neokestose, on the Caco-2 cell line via inhibition of expression of nuclear factor-κB and cyclooxygenase-2. Mol Med Rep. 2015;12:1114-8 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:150
  • 免疫印迹; 人类
Gao Y, Chen Y, Xu D, Wang J, Yu G. Differential expression of ANXA1 in benign human gastrointestinal tissues and cancers. BMC Cancer. 2014;14:520 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Malaviya A, Sylvester P. Synergistic Antiproliferative Effects of Combined ? -Tocotrienol and PPAR ? Antagonist Treatment Are Mediated through PPAR ? -Independent Mechanisms in Breast Cancer Cells. PPAR Res. 2014;2014:439146 pubmed 出版商
  • 免疫印迹; 小鼠
Sharma A, Huard C, Vernochet C, Ziemek D, Knowlton K, Tyminski E, et al. Brown fat determination and development from muscle precursor cells by novel action of bone morphogenetic protein 6. PLoS ONE. 2014;9:e92608 pubmed 出版商
Kunchana K, Jarisarapurin W, Chularojmontri L, Wattanapitayakul S. Potential Use of Amla (Phyllanthus emblica L.) Fruit Extract to Protect Skin Keratinocytes from Inflammation and Apoptosis after UVB Irradiation. Antioxidants (Basel). 2021;10: pubmed 出版商
Wu Z, Xu L, He Y, Xu K, Chen Z, Moqbel S, et al. DUSP5 suppresses interleukin-1β-induced chondrocyte inflammation and ameliorates osteoarthritis in rats. Aging (Albany NY). 2020;12:26029-26046 pubmed 出版商
Li X, Huang R, Liu K, Li M, Luo H, Cui L, et al. Fucoxanthin attenuates LPS-induced acute lung injury via inhibition of the TLR4/MyD88 signaling axis. Aging (Albany NY). 2020;13:2655-2667 pubmed 出版商
Mohamed M, Zaitone S, Ahmed A, Mehanna E, El Sayed N. Raspberry Ketones Attenuate Cyclophosphamide-Induced Pulmonary Toxicity in Mice through Inhibition of Oxidative Stress and NF-ΚB Pathway. Antioxidants (Basel). 2020;9: pubmed 出版商
Zhao M, Wang Y, Zhao Y, He S, Zhao R, Song Y, et al. Caspase-3 knockout attenuates radiation-induced tumor repopulation via impairing the ATM/p53/Cox-2/PGE2 pathway in non-small cell lung cancer. Aging (Albany NY). 2020;12:21758-21776 pubmed 出版商
Shamsi F, Xue R, Huang T, Lundh M, Liu Y, Leiria L, et al. FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis. Nat Commun. 2020;11:1421 pubmed 出版商
Yan S, Ding H, Peng J, Wang X, Pang C, Wei J, et al. Down-regulation of protease-activated receptor 2 ameliorated osteoarthritis in rats through regulation of MAPK/NF-κB signaling pathway in vivo and in vitro. Biosci Rep. 2020;40: pubmed 出版商
Kim I, Rao G, Zhao X, Fan R, Avantaggiati M, Wang Y, et al. Mutant GTF2I induces cell transformation and metabolic alterations in thymic epithelial cells. Cell Death Differ. 2020;27:2263-2279 pubmed 出版商
Koeberle S, Gollowitzer A, Laoukili J, Kranenburg O, Werz O, Koeberle A, et al. Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms. Redox Biol. 2020;28:101388 pubmed 出版商
Kim H, Baek J, Park S, Kim J, Son H, Park G, et al. Anti-inflammatory effect of Vaccinium oldhamii stems through inhibition of NF-κB and MAPK/ATF2 signaling activation in LPS-stimulated RAW264.7 cells. BMC Complement Altern Med. 2019;19:291 pubmed 出版商
Hedberg M, Peyser N, Bauman J, Gooding W, Li H, Bhola N, et al. Use of nonsteroidal anti-inflammatory drugs predicts improved patient survival for PIK3CA-altered head and neck cancer. J Exp Med. 2019;216:419-427 pubmed 出版商
Shi C, Guan Y, Zeng L, Liu G, Zhu Y, Xu H, et al. High COX-2 expression contributes to a poor prognosis through the inhibition of chemotherapy-induced senescence in nasopharyngeal carcinoma. Int J Oncol. 2018;53:1138-1148 pubmed 出版商
Yao K, Lee S, Peng C, Lim D, Yamamoto H, Ryu J, et al. RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation. Oncogene. 2018;37:3501-3513 pubmed 出版商
Wang P, Mao Z, Pan Q, Lu R, Huang X, Shang X, et al. Histone deacetylase-4 and histone deacetylase-8 regulate interleukin-1β-induced cartilage catabolic degradation through MAPK/JNK and ERK pathways. Int J Mol Med. 2018;41:2117-2127 pubmed 出版商
Zhang X, Ma Z, Yuan Y, Xu S, Wei W, Song P, et al. Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling. Cell Death Dis. 2018;9:102 pubmed 出版商
Fong L, Taccioli C, Jing R, Smalley K, Alder H, Jiang Y, et al. MicroRNA dysregulation and esophageal cancer development depend on the extent of zinc dietary deficiency. Oncotarget. 2016;7:10723-38 pubmed 出版商
Onodera Y, Teramura T, Takehara T, Shigi K, Fukuda K. Reactive oxygen species induce Cox-2 expression via TAK1 activation in synovial fibroblast cells. FEBS Open Bio. 2015;5:492-501 pubmed 出版商
Lin X, Yi Z, Diao J, Shao M, Zhao L, Cai H, et al. ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition. J Transl Med. 2014;12:105 pubmed 出版商
Bao M, Zhang Y, Lou X, Xiao Y, Cheng Y, Zhou H. Puerarin protects endothelial cells from oxidized low density lipoprotein induced injuries via the suppression of LOX-1 and induction of eNOS. Can J Physiol Pharmacol. 2014;92:299-306 pubmed 出版商
Li H, Zhu F, Sun Y, Li B, Oi N, Chen H, et al. Select dietary phytochemicals function as inhibitors of COX-1 but not COX-2. PLoS ONE. 2013;8:e76452 pubmed 出版商
产品信息
SKU号 :
12282P
产品名称 :
Cox2(D5H5)XP®兔单克隆抗体
规格 :
40微升
Price-(USD) :
135美元
物种x :
H, M, R, (Mk)
应用 :
流式细胞仪
产品种类 :
免疫学和炎症
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
74
宿主 :
靶标 :
环氧合酶-2/Cox2
最初蛋白 :
COX-2
别名 :
COX-2,COX2,Cyclooxygenase-2,GRIPGHS,PGG/HS,PGH synthase 2,PGH2,PGHS-2,PHS II,PHS-2,PTGS2,Prostaglandin G/H synthase 2,Prostaglandin H2 synthase 2,Prostaglandin-endoperoxide synthase 2,cyclooxygenase 2b,hCox-2,prostaglandin G/H synthase and cyclooxygenase,prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。