产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Stat3
目录 :
12640
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D3Z2G
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, ChIP-Seq, proximity ligation assay, 免疫印迹基因敲除验证
文章摘录数: 44
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1000; 图 4c
Correia de Sousa M, Calo N, Sobolewski C, Gjorgjieva M, Clement S, Maeder C, et al. Mir-21 Suppression Promotes Mouse Hepatocarcinogenesis. Cancers (Basel). 2021;13: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2a
Liu Y, Lin J, Chen Y, Li Z, Zhou J, Lu X, et al. Omega‑3 polyunsaturated fatty acids inhibit IL‑11/STAT3 signaling in hepatocytes during acetaminophen hepatotoxicity. Int J Mol Med. 2021;48: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 4e
Shani O, Raz Y, Monteran L, Scharff Y, Levi Galibov O, Megides O, et al. Evolution of fibroblasts in the lung metastatic microenvironment is driven by stage-specific transcriptional plasticity. elife. 2021;10: pubmed 出版商
  • 免疫组化; 小鼠; 图 7c
Shang L, Ren H, Wang S, Liu H, Hu A, Gou P, et al. SS-31 Protects Liver from Ischemia-Reperfusion Injury via Modulating Macrophage Polarization. Oxid Med Cell Longev. 2021;2021:6662156 pubmed 出版商
  • 免疫印迹; 人类; 图 2d
Dahou H, Minati M, Jacquemin P, Assi M. Genetic Inactivation of Peroxiredoxin-I Impairs the Growth of Human Pancreatic Cancer Cells. Antioxidants (Basel). 2021;10: pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Talwar D, Messens J, Dick T. A role for annexin A2 in scaffolding the peroxiredoxin 2-STAT3 redox relay complex. Nat Commun. 2020;11:4512 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 4d
Muller A, Dickmanns A, Resch C, Schakel K, Hailfinger S, Dobbelstein M, et al. The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. J Clin Invest. 2020;: pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Gu J, Zhang Y, Wang X, Xiang J, Deng S, Wu D, et al. Matrine inhibits the growth of natural killer/T-cell lymphoma cells by modulating CaMKIIγ-c-Myc signaling pathway. BMC Complement Med Ther. 2020;20:214 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 3d
Liang Y, Luo J, Yang N, Wang S, Ye M, Pan G. Activation of the IL-1β/KLF2/HSPH1 pathway promotes STAT3 phosphorylation in alveolar macrophages during LPS-induced acute lung injury. Biosci Rep. 2020;40: pubmed 出版商
  • ChIP-Seq; 人类; ; 图 6f
Martínez Fábregas J, Wilmes S, Wang L, Hafer M, Pohler E, Lokau J, et al. Kinetics of cytokine receptor trafficking determine signaling and functional selectivity. elife. 2019;8: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 1a
Soutto M, Chen Z, Bhat A, Wang L, Zhu S, Gomaa A, et al. Activation of STAT3 signaling is mediated by TFF1 silencing in gastric neoplasia. Nat Commun. 2019;10:3039 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7c
Wang E, Dai Z, Ferrante A, Drake C, Christiano A. A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth. Cell Stem Cell. 2019;: pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 4d
Jia Q, Yang F, Huang W, Zhang Y, Bao B, Li K, et al. Low Levels of Sox2 are required for Melanoma Tumor-Repopulating Cell Dormancy. Theranostics. 2019;9:424-435 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Song J, Zhang X, Liao Z, Liang H, Chu L, Dong W, et al. 14-3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling. J Exp Clin Cancer Res. 2019;38:3 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3d
Pan H, Palekar R, Hou K, Bacon J, Yan H, Springer L, et al. Anti-JNK2 peptide-siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice. Int J Nanomedicine. 2018;13:5187-5205 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1d
  • 免疫印迹; 小鼠; 1:1000; 图 1d
Zhang C, Wang C, Jiang M, Gu C, Xiao J, Chen X, et al. Act1 is a negative regulator in T and B cells via direct inhibition of STAT3. Nat Commun. 2018;9:2745 pubmed 出版商
  • 免疫印迹; 人类; 图 5c
Song J, Zhang X, Ge Q, Yuan C, Chu L, Liang H, et al. CRISPR/Cas9-mediated knockout of HBsAg inhibits proliferation and tumorigenicity of HBV-positive hepatocellular carcinoma cells. J Cell Biochem. 2018;119:8419-8431 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6a
Giurisato E, Xu Q, Lonardi S, Telfer B, Russo I, Pearson A, et al. Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. Proc Natl Acad Sci U S A. 2018;115:E2801-E2810 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3b
  • 免疫印迹; 人类; 1:1000; 图 4c
Oldrini B, Hsieh W, Erdjument Bromage H, Codega P, Carro M, Curiel García A, et al. EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer. Nat Commun. 2017;8:2035 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Almeida L, Neto M, Sousa L, Tannous M, Curti C, Leopoldino A. SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation. Oncotarget. 2017;8:26802-26818 pubmed 出版商
  • ChIP-Seq; 小鼠; 图 7
Conaway E, de Oliveira D, McInnis C, Snapper S, Horwitz B. Inhibition of Inflammatory Gene Transcription by IL-10 Is Associated with Rapid Suppression of Lipopolysaccharide-Induced Enhancer Activation. J Immunol. 2017;198:2906-2915 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 2b
Hsia H, Hutti J, Baldwin A. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity. J Biol Chem. 2017;292:5405-5417 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6e
  • 免疫印迹; 人类; 图 5g
Ganta V, Choi M, Kutateladze A, Annex B. VEGF165b Modulates Endothelial VEGFR1-STAT3 Signaling Pathway and Angiogenesis in Human and Experimental Peripheral Arterial Disease. Circ Res. 2017;120:282-295 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 5
  • 免疫印迹; 人类; 1:1000; 图 3
Jiang S, Gao Y, Hou W, Liu R, Qi X, Xu X, et al. Sinomenine inhibits A549 human lung cancer cell invasion by mediating the STAT3 signaling pathway. Oncol Lett. 2016;12:1380-1386 pubmed
  • 免疫印迹; 人类; 图 3
Pandiri I, Chen Y, Joe Y, Kim H, Park J, Chung H, et al. Tristetraprolin mediates the anti-proliferative effects of metformin in breast cancer cells. Breast Cancer Res Treat. 2016;156:57-64 pubmed 出版商
  • 免疫印迹; 人类; 图 1
  • 免疫印迹; 小鼠; 图 1
M L, P P, T K, M P, E S, J P, et al. Essential role of HDAC6 in the regulation of PD-L1 in melanoma. Mol Oncol. 2016;10:735-750 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4a
Park K, Yun H, Quang T, Oh H, Lee D, Auh Q, et al. 4-Methoxydalbergione suppresses growth and induces apoptosis in human osteosarcoma cells in vitro and in vivo xenograft model through down-regulation of the JAK2/STAT3 pathway. Oncotarget. 2016;7:6960-71 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1f
Mazur P, Herner A, Mello S, Wirth M, Hausmann S, Sánchez Rivera F, et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nat Med. 2015;21:1163-71 pubmed 出版商
  • proximity ligation assay; 小鼠; 图 s26
Yoon J, Sudo K, Kuroda M, Kato M, Lee I, Han J, et al. Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation. Nat Commun. 2015;6:7600 pubmed 出版商
  • 免疫印迹; 人类; 图 2d
Marozin S, Altomonte J, Muñoz Álvarez K, Rizzani A, De Toni E, Thasler W, et al. STAT3 inhibition reduces toxicity of oncolytic VSV and provides a potentially synergistic combination therapy for hepatocellular carcinoma. Cancer Gene Ther. 2015;22:317-25 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Lu K, Fang X, Feng L, Jiang Y, Zhou X, Liu X, et al. The STAT3 inhibitor WP1066 reverses the resistance of chronic lymphocytic leukemia cells to histone deacetylase inhibitors induced by interleukin-6. Cancer Lett. 2015;359:250-8 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Kuo H, Huang Y, Tseng C, Chen Y, Chang Y, Shih H, et al. PML represses lung cancer metastasis by suppressing the nuclear EGFR-mediated transcriptional activation of MMP2. Cell Cycle. 2014;13:3132-42 pubmed 出版商
Yamaguchi M, Osuka S, Murata T, Ramos J. Progression-free survival of prostate cancer patients is prolonged with a higher regucalcin expression in the tumor tissues: Overexpressed regucalcin suppresses the growth and bone activity in human prostate cancer cells. Transl Oncol. 2021;14:100955 pubmed 出版商
Xia R, Chen J, Gao J, Luo X, Ke C, Ren C, et al. Inhibition of esophageal-carcinoma cell proliferation by genistein via suppression of JAK1/2-STAT3 and AKT/MDM2/p53 signaling pathways. Aging (Albany NY). 2020;12:6240-6259 pubmed 出版商
Zheng B, Yang Y, Han Q, Yin C, Pan Z, Zhang J. STAT3 directly regulates NKp46 transcription in NK cells of HBeAg-negative CHB patients. J Leukoc Biol. 2019;: pubmed 出版商
Boichuck M, Zorea J, Elkabets M, Wolfson M, Fraifeld V. c-Met as a new marker of cellular senescence. Aging (Albany NY). 2019;11:2889-2897 pubmed 出版商
Jacobsson H, Harrison H, Hughes E, Persson E, Rhost S, Fitzpatrick P, et al. Hypoxia-induced secretion stimulates breast cancer stem cell regulatory signalling pathways. Mol Oncol. 2019;13:1693-1705 pubmed 出版商
Razidlo G, Burton K, McNiven M. Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42. J Biol Chem. 2018;293:11143-11153 pubmed 出版商
Barben M, Ail D, Storti F, Klee K, Schori C, Samardzija M, et al. Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress. Cell Death Differ. 2018;25:2071-2085 pubmed 出版商
Meyer zu Horste G, Przybylski D, Schramm M, Wang C, Schnell A, Lee Y, et al. Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1. Immunity. 2018;48:556-569.e7 pubmed 出版商
Inoue Yamauchi A, Itagaki H, Oda H. Eicosapentaenoic acid attenuates obesity-related hepatocellular carcinogenesis. Carcinogenesis. 2017;: pubmed 出版商
Murakami S, Suzuki T, Harigae H, Romeo P, Yamamoto M, Motohashi H. NRF2 Activation Impairs Quiescence and Bone Marrow Reconstitution Capacity of Hematopoietic Stem Cells. Mol Cell Biol. 2017;37: pubmed 出版商
Pan Y, Wang S, Su B, Zhou F, Xu T, Zhang R, et al. Stat3 contributes to cancer progression by regulating Jab1/Csn5 expression. Oncogene. 2017;36:1069-1079 pubmed 出版商
Li Y, Han B, Li F, Yu J, Dong Z, Niu G, et al. High Glucose Induces Down-Regulated GRIM-19 Expression to Activate STAT3 Signaling and Promote Cell Proliferation in Cell Culture. PLoS ONE. 2016;11:e0153659 pubmed 出版商
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。