出版应用/物种/样本/稀释 | 参考文献 |
---|
- 免疫细胞化学; 人类; 1:400; 图 5c
- 免疫印迹; 人类; 1:400; 图 5a
| Hong Z, Wang Z, Zhou B, Wang J, Tong H, Liao Y, et al. Effects of evodiamine on PI3K/Akt and MAPK/ERK signaling pathways in pancreatic cancer cells. Int J Oncol. 2020;56:783-793 pubmed 出版商
|
| Liu T, Han S, Dai Q, Zheng J, Liu C, Li S, et al. IL-17A-Mediated Excessive Autophagy Aggravated Neuronal Ischemic Injuries via Src-PP2B-mTOR Pathway. Front Immunol. 2019;10:2952 pubmed 出版商
|
| Huang X, Ni B, Xi Y, Chu X, Zhang R, You H. Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis. Aging (Albany NY). 2019;11:12532-12545 pubmed 出版商
|
- 免疫印迹; 小鼠; 图 4b
- 免疫印迹; 人类; 图 5a
| Zhang Y, Cao Y, Chen J, Qin H, Yang L. A New Possible Mechanism by Which Punicalagin Protects against Liver Injury Induced by Type 2 Diabetes Mellitus: Upregulation of Autophagy via the Akt/FoxO3a Signaling Pathway. J Agric Food Chem. 2019;: pubmed 出版商
|
| Malik N, Yan H, Moshkovich N, Palangat M, Yang H, Sanchez V, et al. The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription. Nat Commun. 2019;10:2071 pubmed 出版商
|
| Zhou B, Kreuzer J, Kumsta C, Wu L, Kamer K, Cedillo L, et al. Mitochondrial Permeability Uncouples Elevated Autophagy and Lifespan Extension. Cell. 2019;177:299-314.e16 pubmed 出版商
|
- 免疫印迹; 人类; 图 2f
- 免疫印迹; 小鼠; 图 2e
| Vodnala S, Eil R, Kishton R, Sukumar M, Yamamoto T, Ha N, et al. T cell stemness and dysfunction in tumors are triggered by a common mechanism. Science. 2019;363: pubmed 出版商
|
| Mukhopadhyay U, Chanda S, Patra U, Mukherjee A, Rana S, Mukherjee A, et al. Synchronized Orchestration of miR-99b and let-7g Positively Regulates Rotavirus Infection by Modulating Autophagy. Sci Rep. 2019;9:1318 pubmed 出版商
|
| Liu N, Luo J, Kuang D, Xu S, Duan Y, Xia Y, et al. Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression. J Clin Invest. 2019;129:631-646 pubmed 出版商
|
- 免疫印迹基因敲除验证; 人类; 1:1000; 图 4b
- 免疫印迹; 人类; 1:1000; 图 4c, 4e
| Zhang J, Tan P, Guo L, Gong J, Ma J, Li J, et al. p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance. Oncogene. 2019;38:1905-1919 pubmed 出版商
|
| Rivera Reyes A, Ye S, E Marino G, Egolf S, E Ciotti G, Chor S, et al. YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma. Cell Death Dis. 2018;9:1108 pubmed 出版商
|
- 免疫组化; 小鼠; 图 1a
- 免疫印迹; 小鼠; 1:1000; 图 5c
| Vera Ramirez L, Vodnala S, Nini R, Hunter K, Green J. Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence. Nat Commun. 2018;9:1944 pubmed 出版商
|
| Liu L, An D, Xu J, Shao B, Li X, Shi J. Ac2-26 Induces IKKβ Degradation Through Chaperone-Mediated Autophagy Via HSPB1 in NCM-Treated Microglia. Front Mol Neurosci. 2018;11:76 pubmed 出版商
|
- 免疫组化-冰冻切片; 小鼠; 1:500; 图 4a
- 免疫细胞化学; 人类; 1:500; 图 4d
| Nguyen H, Noguchi S, Sugie K, Matsuo Y, Nguyen C, Koito H, et al. Small-Vessel Vasculopathy Due to Aberrant Autophagy in LAMP-2 Deficiency. Sci Rep. 2018;8:3326 pubmed 出版商
|
| Kim J, Kim Y, Kim J, Park D, Bae H, Lee D, et al. YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation. J Clin Invest. 2017;127:3441-3461 pubmed 出版商
|
| Liu C, Choi H, Johnson Z, Tian J, Shapiro I, Risbud M. Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus. Sci Rep. 2017;7:4543 pubmed 出版商
|
- 免疫组化-石蜡切片; 小鼠; 图 3d
- 免疫印迹; 小鼠; 图 3a
| Xiao Y, Yang Z, Wu Q, Jiang X, Yuan Y, Chang W, et al. Cucurbitacin B Protects Against Pressure Overload Induced Cardiac Hypertrophy. J Cell Biochem. 2017;118:3899-3910 pubmed 出版商
|
| Mu Y, Yan W, Yin T, Zhang Y, Li J, Yang J. Diet-induced obesity impairs spermatogenesis: a potential role for autophagy. Sci Rep. 2017;7:43475 pubmed 出版商
|
| Villar V, Nguyen T, Delcroix V, Terés S, Bouchecareilh M, Salin B, et al. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Nat Commun. 2017;8:14124 pubmed 出版商
|
- 免疫细胞化学; 人类; 图 2b
- 免疫印迹; 人类; 图 2a
| Capizzi M, Strappazzon F, Cianfanelli V, Papaleo E, Cecconi F. MIR7-3HG, a MYC-dependent modulator of cell proliferation, inhibits autophagy by a regulatory loop involving AMBRA1. Autophagy. 2017;13:554-566 pubmed 出版商
|
| Silva S, Levy D, Ruiz J, de Melo T, Isaac C, Fidelis M, et al. Oxysterols in adipose tissue-derived mesenchymal stem cell proliferation and death. J Steroid Biochem Mol Biol. 2017;169:164-175 pubmed 出版商
|
| Mukhopadhyay C, Triplett A, Bargar T, HECKMAN C, Wagner K, Naramura M. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation. Proc Natl Acad Sci U S A. 2016;113:E8228-E8237 pubmed 出版商
|
- 免疫细胞化学; 人类; 图 8g
- 免疫印迹; 人类; 图 8a
| Cao L, Zhang L, Zhao X, Zhang Y. A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells. PLoS ONE. 2016;11:e0161025 pubmed 出版商
|
| Choi H, Merceron C, Mangiavini L, Seifert E, Schipani E, Shapiro I, et al. Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling. Autophagy. 2016;12:1631-46 pubmed 出版商
|
| Stephenson E, Ragauskas A, Jaligama S, Redd J, Parvathareddy J, Peloquin M, et al. Exposure to environmentally persistent free radicals during gestation lowers energy expenditure and impairs skeletal muscle mitochondrial function in adult mice. Am J Physiol Endocrinol Metab. 2016;310:E1003-15 pubmed 出版商
|
- 免疫组化-冰冻切片; 小鼠; 1:500; 图 6
| Kumar R, Narasimhan M, Shanmugam G, Hong J, Devarajan A, Palaniappan S, et al. Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress. J Transl Med. 2016;14:86 pubmed 出版商
|
- 免疫细胞化学; 人类; 1:50; 图 6
- 免疫印迹; 人类; 图 2
| Zou M, Zhu W, Wang L, Shi L, Gao R, Ou Y, et al. AEG-1/MTDH-activated autophagy enhances human malignant glioma susceptibility to TGF-β1-triggered epithelial-mesenchymal transition. Oncotarget. 2016;7:13122-38 pubmed 出版商
|
- 免疫印迹; 小鼠; 图 3
- 免疫印迹; 人类; 图 s5
| Han X, Tai H, Wang X, Wang Z, Zhou J, Wei X, et al. AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation. Aging Cell. 2016;15:416-27 pubmed 出版商
|
| Duncan J, Zhang X, Wang N, Johnson S, Harris S, Udemgba C, et al. Binge ethanol exposure increases the Krüppel-like factor 11-monoamine oxidase (MAO) pathway in rats: Examining the use of MAO inhibitors to prevent ethanol-induced brain injury. Neuropharmacology. 2016;105:329-340 pubmed 出版商
|
- 免疫细胞化学; 人类; 1:100; 图 4a
- 免疫印迹; 人类; 1:1000
| Pawar K, Hanisch C, Palma Vera S, Einspanier R, Sharbati S. Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy. Sci Rep. 2016;6:19416 pubmed 出版商
|
- 免疫组化; 小鼠; 1:400; 图 s5
- 免疫印迹; 人类; 1:1000; 图 3
| Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich M, Lim R, et al. FOXO1 couples metabolic activity and growth state in the vascular endothelium. Nature. 2016;529:216-20 pubmed 出版商
|
| Mercau M, Repetto E, Perez M, Martinez Calejman C, Sánchez Puch S, Finkielstein C, et al. Moderate Exercise Prevents Functional Remodeling of the Anterior Pituitary Gland in Diet-Induced Insulin Resistance in Rats: Role of Oxidative Stress and Autophagy. Endocrinology. 2016;157:1135-45 pubmed 出版商
|
| Hu J, Man W, Shen M, Zhang M, Lin J, Wang T, et al. Luteolin alleviates post-infarction cardiac dysfunction by up-regulating autophagy through Mst1 inhibition. J Cell Mol Med. 2016;20:147-56 pubmed 出版商
|
- 免疫细胞化学; 人类; 图 1
- 免疫印迹; 人类; 图 1
| Qin W, Li C, Zheng W, Guo Q, Zhang Y, Kang M, et al. Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells. Oncotarget. 2015;6:39839-54 pubmed 出版商
|
- 免疫细胞化学; 人类; 图 5
- 免疫印迹; 人类; 图 6
| Ray A, Vasudevan S, Sengupta S. 6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death. PLoS ONE. 2015;10:e0137614 pubmed 出版商
|
| Saliba J, Saint Martin C, Di Stefano A, Lenglet G, Marty C, Keren B, et al. Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies. Nat Genet. 2015;47:1131-40 pubmed 出版商
|
| Sakabe I, Hu R, Jin L, Clarke R, Kasid U. TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling. Breast Cancer Res Treat. 2015;153:285-97 pubmed 出版商
|
| Zhang W, Hou J, Wang X, Jiang R, Yin Y, Ji J, et al. PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis. Oncotarget. 2015;6:9420-33 pubmed
|
| Lonskaya I, Hebron M, Chen W, Schachter J, Moussa C. Tau deletion impairs intracellular β-amyloid-42 clearance and leads to more extracellular plaque deposition in gene transfer models. Mol Neurodegener. 2014;9:46 pubmed 出版商
|
| Zhu Z, Zhang P, Li N, Kiang K, Cheng S, Wong V, et al. Lovastatin Enhances Cytotoxicity of Temozolomide via Impairing Autophagic Flux in Glioblastoma Cells. Biomed Res Int. 2019;2019:2710693 pubmed 出版商
|
| Yang Y, Willis T, Button R, Strang C, Fu Y, Wen X, et al. Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response. Nat Commun. 2019;10:3759 pubmed 出版商
|
| Barroso González J, García Expósito L, Hoang S, Lynskey M, Roncaioli J, Ghosh A, et al. RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres. Mol Cell. 2019;76:11-26.e7 pubmed 出版商
|
| Selyunin A, Hutchens S, McHardy S, Mukhopadhyay S. Tamoxifen blocks retrograde trafficking of Shiga toxin 1 and 2 and protects against lethal toxicosis. Life Sci Alliance. 2019;2: pubmed 出版商
|
| Shi C, Nabar N, Huang N, Kehrl J. SARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes. Cell Death Discov. 2019;5:101 pubmed 出版商
|
| Wang D, He X, He Q. Combining use of Phillyrin and autophagy blocker alleviates laryngeal squamous cell carcinoma via AMPK/mTOR/p70S6K signaling. Biosci Rep. 2019;: pubmed 出版商
|
| Chen S, Li Y, Yin X, Li S, Zhu Y, Fan Y, et al. Recombinant adenoviruses expressing apoptin suppress the growth of MCF‑7 breast cancer cells and affect cell autophagy. Oncol Rep. 2019;41:2818-2832 pubmed 出版商
|
| Chun J, Zhang J, Wilkins M, Subramanian B, Riella C, Magraner J, et al. Recruitment of APOL1 kidney disease risk variants to lipid droplets attenuates cell toxicity. Proc Natl Acad Sci U S A. 2019;116:3712-3721 pubmed 出版商
|
| Narayana Y, Gadgil C, Mote R, Rajan R, Subramanyam D. Clathrin-Mediated Endocytosis Regulates a Balance between Opposing Signals to Maintain the Pluripotent State of Embryonic Stem Cells. Stem Cell Reports. 2019;12:152-164 pubmed 出版商
|
| Feng J, Zhang Y, She X, Sun Y, Fan L, Ren X, et al. Hypermethylated gene ANKDD1A is a candidate tumor suppressor that interacts with FIH1 and decreases HIF1α stability to inhibit cell autophagy in the glioblastoma multiforme hypoxia microenvironment. Oncogene. 2019;38:103-119 pubmed 出版商
|
| Bieri G, Lucin K, O Brien C, Zhang H, Villeda S, Wyss Coray T. Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration. Mol Neurodegener. 2018;13:68 pubmed 出版商
|
| Martínez Fábregas J, Prescott A, van Kasteren S, Pedrioli D, McLean I, Moles A, et al. Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis. Nat Commun. 2018;9:5343 pubmed 出版商
|
| Zhang P, Guan Y, Chen J, Li X, McConnell B, Zhou W, et al. Contribution of p62/SQSTM1 to PDGF-BB-induced myofibroblast-like phenotypic transition in vascular smooth muscle cells lacking Smpd1 gene. Cell Death Dis. 2018;9:1145 pubmed 出版商
|
| Kuno A, Hosoda R, Sebori R, Hayashi T, Sakuragi H, Tanabe M, et al. Resveratrol Ameliorates Mitophagy Disturbance and Improves Cardiac Pathophysiology of Dystrophin-deficient mdx Mice. Sci Rep. 2018;8:15555 pubmed 出版商
|
| Cloer E, Siesser P, Cousins E, Goldfarb D, Mowrey D, Harrison J, et al. p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2. Mol Cell Biol. 2018;38: pubmed 出版商
|
| Yuan B, Yao M, Wang X, Sato A, Okazaki A, Komuro H, et al. Antitumor activity of arsenite in combination with tetrandrine against human breast cancer cell line MDA-MB-231 in vitro and in vivo. Cancer Cell Int. 2018;18:113 pubmed 出版商
|
| Wang X, de Carvalho Ribeiro M, Iracheta Vellve A, Lowe P, Ambade A, Satishchandran A, et al. Macrophage-Specific Hypoxia-Inducible Factor-1α Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis. Hepatology. 2018;: pubmed 出版商
|
| Che Y, Wang Z, Yuan Y, Zhang N, Jin Y, Wan C, et al. Role of autophagy in a model of obesity: A long‑term high fat diet induces cardiac dysfunction. Mol Med Rep. 2018;18:3251-3261 pubmed 出版商
|
| Durbas M, Pabisz P, Wawak K, Wiśniewska A, Boratyn E, Nowak I, et al. GD2 ganglioside-binding antibody 14G2a and specific aurora A kinase inhibitor MK-5108 induce autophagy in IMR-32 neuroblastoma cells. Apoptosis. 2018;23:492-511 pubmed 出版商
|
| Bhattacharjee S, Bose P, Patel K, Roy S, Gain C, Gowda H, et al. Transcriptional and epigenetic modulation of autophagy promotes EBV oncoprotein EBNA3C induced B-cell survival. Cell Death Dis. 2018;9:605 pubmed 出版商
|
| Sorbara M, Foerster E, Tsalikis J, Abdel Nour M, Mangiapane J, Sirluck Schroeder I, et al. Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria. Cell Host Microbe. 2018;23:644-652.e5 pubmed 出版商
|
| Roa Mansergas X, Fadó R, Atari M, Mir J, Muley H, Serra D, et al. CPT1C promotes human mesenchymal stem cells survival under glucose deprivation through the modulation of autophagy. Sci Rep. 2018;8:6997 pubmed 出版商
|
| Duan X, Kong Z, Mai X, Lan Y, Liu Y, Yang Z, et al. Autophagy inhibition attenuates hyperoxaluria-induced renal tubular oxidative injury and calcium oxalate crystal depositions in the rat kidney. Redox Biol. 2018;16:414-425 pubmed 出版商
|
| Gao F, Li G, Liu C, Gao H, Wang H, Liu W, et al. Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells. J Cell Biol. 2018;217:2103-2119 pubmed 出版商
|
| St Gelais C, Kim S, Maksimova V, Buzovetsky O, Knecht K, Shepard C, et al. A Cyclin-Binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation. J Virol. 2018;92: pubmed 出版商
|
| Hwang I, Oh H, Santo E, Kim D, Chen J, Bronson R, et al. FOXO protects against age-progressive axonal degeneration. Aging Cell. 2018;17: pubmed 出版商
|
| Al Ramahi I, Giridharan S, Chen Y, Patnaik S, Safren N, Hasegawa J, et al. Inhibition of PIP4K? ameliorates the pathological effects of mutant huntingtin protein. elife. 2017;6: pubmed 出版商
|
| Kang H, Kumar D, Liao G, Lichti Kaiser K, Gerrish K, Liao X, et al. GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation. J Clin Invest. 2017;127:4326-4337 pubmed 出版商
|
| Lina T, Luo T, Velayutham T, Das S, McBride J. Ehrlichia Activation of Wnt-PI3K-mTOR Signaling Inhibits Autolysosome Generation and Autophagic Destruction by the Mononuclear Phagocyte. Infect Immun. 2017;85: pubmed 出版商
|
| LÅ‘rincz P, Tóth S, BenkÅ‘ P, Lakatos Z, Boda A, Glatz G, et al. Rab2 promotes autophagic and endocytic lysosomal degradation. J Cell Biol. 2017;216:1937-1947 pubmed 出版商
|
| Min M, Chen X, Wang P, Landeck L, Chen J, Li W, et al. Role of keratin 24 in human epidermal keratinocytes. PLoS ONE. 2017;12:e0174626 pubmed 出版商
|
| Horne D, Graustein A, Shah J, Peterson G, Savlov M, Steele S, et al. Human ULK1 Variation and Susceptibility to Mycobacterium tuberculosis Infection. J Infect Dis. 2016;214:1260-7 pubmed 出版商
|
| Han D, Wan C, Liu F, Xu X, Jiang L, Xu J. Jujuboside A Protects H9C2 Cells from Isoproterenol-Induced Injury via Activating PI3K/Akt/mTOR Signaling Pathway. Evid Based Complement Alternat Med. 2016;2016:9593716 pubmed 出版商
|
| Wang H, Yu Y, Jiang Z, Cao W, Wang Z, Dou J, et al. Next-generation proteasome inhibitor MLN9708 sensitizes breast cancer cells to doxorubicin-induced apoptosis. Sci Rep. 2016;6:26456 pubmed 出版商
|
| Gómez SanMiguel A, Villanúa M, Martín A, López Calderón A. D-TRP(8)-γMSH Prevents the Effects of Endotoxin in Rat Skeletal Muscle Cells through TNFα/NF-KB Signalling Pathway. PLoS ONE. 2016;11:e0155645 pubmed 出版商
|
| Li G, Ying L, Wang H, Wei S, Chen J, Chen Y, et al. Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways. Oncotarget. 2016;7:17970-85 pubmed 出版商
|
| Chen T, Syu J, Lin T, Cheng H, Lu F, Wang C. Chloroquine alleviates etoposide-induced centrosome amplification by inhibiting CDK2 in adrenocortical tumor cells. Oncogenesis. 2015;4:e180 pubmed 出版商
|
| Sun B, Kim J, Choi J, Hwang S, Sung J. Fluoxetine Decreases the Proliferation and Adipogenic Differentiation of Human Adipose-Derived Stem Cells. Int J Mol Sci. 2015;16:16655-68 pubmed 出版商
|
| Choi S, Gonen A, Diehl C, Kim J, Almazan F, Witztum J, et al. SYK regulates macrophage MHC-II expression via activation of autophagy in response to oxidized LDL. Autophagy. 2015;11:785-95 pubmed 出版商
|
| Hotokezaka Y, Katayama I, van Leyen K, Nakamura T. GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses. Cell Death Dis. 2015;6:e1719 pubmed 出版商
|
| Filippi Chiela E, Bueno E Silva M, Thomé M, Lenz G. Single-cell analysis challenges the connection between autophagy and senescence induced by DNA damage. Autophagy. 2015;11:1099-113 pubmed 出版商
|
| Zhao X, Liu G, Shen H, Gao B, Li X, Fu J, et al. Liraglutide inhibits autophagy and apoptosis induced by high glucose through GLP-1R in renal tubular epithelial cells. Int J Mol Med. 2015;35:684-92 pubmed 出版商
|