产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
NLRP3(D4D8T)兔单克隆抗体
目录 :
15101
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D4D8T
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫印迹基因敲除验证
文章摘录数: 29
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 1b
Opoku E, TRAUGHBER C, Zhang D, Iacano A, Khan M, Han J, et al. Gasdermin D Mediates Inflammation-Induced Defects in Reverse Cholesterol Transport and Promotes Atherosclerosis. Front Cell Dev Biol. 2021;9:715211 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2f, 5d
Chen J, Yang F, Shi S, Liu X, Qin F, Wei X, et al. The Severity of CVB3-Induced Myocarditis Can Be Improved by Blocking the Orchestration of NLRP3 and Th17 in Balb/c Mice. Mediators Inflamm. 2021;2021:5551578 pubmed 出版商
  • 免疫印迹; 人类; 图 6b
Lee S, Kim J, Choi Y, Gong J, Park S, Douangdeuane B, et al. Therapeutic Effects of Dipterocarpus tuberculatus with High Antioxidative Activity Against UV-Induced Photoaging of NHDF Cells and Nude Mice. Antioxidants (Basel). 2021;10: pubmed 出版商
  • 免疫印迹; 小鼠; 1:750; 图 7b
Frenis K, Helmstädter J, Ruan Y, Schramm E, Kalinovic S, Kröller Schön S, et al. Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects. Basic Res Cardiol. 2021;116:31 pubmed 出版商
  • 免疫沉淀; 小鼠; 图 5b
  • 免疫印迹; 小鼠; 1:2000; 图 5b
Zhang W, Tao S, Wang T, Zhang J, Liu X, Li Y, et al. ABRO1 stabilizes the deubiquitinase BRCC3 through inhibiting its degradation mediated by the E3 ubiquitin ligase WWP2. FEBS Lett. 2021;595:169-182 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4g
Jin X, Morro B, Tørresen O, Moiche V, Solbakken M, Jakobsen K, et al. Innovation in Nucleotide-Binding Oligomerization-Like Receptor and Toll-Like Receptor Sensing Drives the Major Histocompatibility Complex-II Free Atlantic Cod Immune System. Front Immunol. 2020;11:609456 pubmed 出版商
  • 免疫印迹; 人类; 图 4b
Sünderhauf A, Raschdorf A, Hicken M, Schlichting H, Fetzer F, Brethack A, et al. GC1qR Cleavage by Caspase-1 Drives Aerobic Glycolysis in Tumor Cells. Front Oncol. 2020;10:575854 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7a, 7b
Hu J, Wang H, Li X, Liu Y, Mi Y, Kong H, et al. Fibrinogen-like protein 2 aggravates nonalcoholic steatohepatitis via interaction with TLR4, eliciting inflammation in macrophages and inducing hepatic lipid metabolism disorder. Theranostics. 2020;10:9702-9720 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s7a
Theivanthiran B, Evans K, Devito N, Plebanek M, Sturdivant M, Wachsmuth L, et al. A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy. J Clin Invest. 2020;130:2570-2586 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1c
  • 免疫印迹; 人类; 图 1b
Teng J, Mei Q, Zhou X, Tang Y, Xiong R, Qiu W, et al. Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer. Cancers (Basel). 2020;12: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3b, 4f, s7b
Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, et al. A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice. Nat Commun. 2019;10:5681 pubmed 出版商
  • 免疫印迹; 大鼠; 图 6b
Qin W, Wu X, Jia Y, Tong X, Guo C, Chen D, et al. Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma. Biomed Pharmacother. 2019;118:109188 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 2s1b
Lim J, Park H, Heisler J, Maculins T, Roose Girma M, Xu M, et al. Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins. elife. 2019;8: pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 2b
Lin L, Xu L, Lv W, Han L, Xiang Y, Fu L, et al. An NLRP3 inflammasome-triggered cytokine storm contributes to Streptococcal toxic shock-like syndrome (STSLS). PLoS Pathog. 2019;15:e1007795 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4d, 4e
Kurundkar D, Kurundkar A, Bone N, Becker E, Liu W, Chacko B, et al. SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury. JCI Insight. 2019;4: pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 s7j
Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, et al. STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nat Commun. 2018;9:5226 pubmed 出版商
  • 免疫印迹; 小鼠; 1:800; 图 2c
Qiu T, Pei P, Yao X, Jiang L, Wei S, Wang Z, et al. Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway. Cell Death Dis. 2018;9:946 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Kosmidou C, Efstathiou N, Hoang M, Notomi S, Konstantinou E, Hirano M, et al. Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration. Sci Rep. 2018;8:461 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6g
Xiao N, Yang L, Yang Y, Liu L, Li J, Liu B, et al. Ginsenoside Rg5 Inhibits Succinate-Associated Lipolysis in Adipose Tissue and Prevents Muscle Insulin Resistance. Front Pharmacol. 2017;8:43 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 9c
Luan L, Patil N, Guo Y, Hernandez A, Bohannon J, Fensterheim B, et al. Comparative Transcriptome Profiles of Human Blood in Response to the Toll-like Receptor 4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A. Sci Rep. 2017;7:40050 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50; 图 6
  • 免疫印迹; 人类; 1:1000; 图 s1
Tseng H, Vong C, Kwan Y, Lee S, Hoi M. TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells. Sci Rep. 2016;6:35016 pubmed 出版商
Zhao J, Ma W, Chen W, Gao J, Li C, Tong Y, et al. AEG-1 aggravates inflammation via promoting NALP3 inflammasome formation in murine endometriosis lesions. Anim Cells Syst (Seoul). 2019;23:407-413 pubmed 出版商
Hughes M, Hooftman A, Angiari S, Tummala P, Zaslona Z, Runtsch M, et al. Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation. Cell Rep. 2019;29:151-161.e5 pubmed 出版商
Labzin L, Bottermann M, Rodriguez Silvestre P, Foss S, Andersen J, Vaysburd M, et al. Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection. EMBO J. 2019;38:e101365 pubmed 出版商
Lang T, Lee J, Elgass K, Pinar A, Tate M, Aitken E, et al. Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation. Nat Commun. 2018;9:2223 pubmed 出版商
Wakamatsu T, Yamamoto S, Ito T, Sato Y, Matsuo K, Takahashi Y, et al. Indoxyl Sulfate Promotes Macrophage IL-1β Production by Activating Aryl Hydrocarbon Receptor/NF-κ/MAPK Cascades, but the NLRP3 inflammasome Was Not Activated. Toxins (Basel). 2018;10: pubmed 出版商
Camilli G, Eren E, Williams D, Aimanianda V, Meunier E, Quintin J. Impaired phagocytosis directs human monocyte activation in response to fungal derived β-glucan particles. Eur J Immunol. 2018;48:757-770 pubmed 出版商
Wang W, Shi Q, Dou S, Li G, Shi X, Jiang X, et al. Negative regulation of Nod-like receptor protein 3 inflammasome activation by T cell Ig mucin-3 protects against peritonitis. Immunology. 2018;153:71-83 pubmed 出版商
Neudecker V, Haneklaus M, Jensen O, Khailova L, Masterson J, Tye H, et al. Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome. J Exp Med. 2017;214:1737-1752 pubmed 出版商
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。