产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
核纤层蛋白A/C抗体
目录 :
2032
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, , domestic rabbit
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
文章摘录数: 56
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 5c
Lin J, Liu H, Fukumoto T, Zundell J, Yan Q, Tang C, et al. Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer. Nat Commun. 2021;12:5321 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4a
Zhou L, Nho K, Haddad M, Cherepacha N, Tubeleviciute Aydin A, Tsai A, et al. Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration. Sci Rep. 2021;11:12695 pubmed 出版商
  • 免疫印迹; 人类; 图 1h
Andrade J, Shi C, Costa A, Choi J, Kim J, Doddaballapur A, et al. Control of endothelial quiescence by FOXO-regulated metabolites. Nat Cell Biol. 2021;23:413-423 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3f
Valbuena Perez J, Linnenberger R, Dembek A, Bruscoli S, Riccardi C, Schulz M, et al. Altered glucocorticoid metabolism represents a feature of macroph-aging. Aging Cell. 2020;19:e13156 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1g
Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, et al. Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes. Nat Commun. 2020;11:859 pubmed 出版商
  • 免疫组化; 人类; 1:1000
Nihei Y, Mori K, Werner G, Arzberger T, Zhou Q, Khosravi B, et al. Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3. Acta Neuropathol. 2020;139:99-118 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s1b
James C, Müller M, Goldberg M, Lenz C, Urlaub H, Kehlenbach R. Proteomic mapping by rapamycin-dependent targeting of APEX2 identifies binding partners of VAPB at the inner nuclear membrane. J Biol Chem. 2019;294:16241-16254 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Gross K, Zhou W, Breindel J, Ouyang J, Jin D, Sokol E, et al. Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium. Cell Rep. 2019;28:394-407.e6 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s1b
Halfmann C, Sears R, Katiyar A, Busselman B, Aman L, Zhang Q, et al. Repair of nuclear ruptures requires barrier-to-autointegration factor. J Cell Biol. 2019;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2a
Guo M, Hartlova A, Gierlinski M, Prescott A, Castellvi J, Losa J, et al. Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages. EMBO J. 2019;38: pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 6b
Brody M, Vanhoutte D, Bakshi C, Liu R, Correll R, Sargent M, et al. Disruption of valosin-containing protein activity causes cardiomyopathy and reveals pleiotropic functions in cardiac homeostasis. J Biol Chem. 2019;294:8918-8929 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1d
Shang X, Shen C, Liu J, Tang L, Zhang H, Wang Y, et al. Serine protease PRSS55 is crucial for male mouse fertility via affecting sperm migration and sperm-egg binding. Cell Mol Life Sci. 2018;75:4371-4384 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s15a
Wang P, Xu J, Wang Y, Cao X. An interferon-independent lncRNA promotes viral replication by modulating cellular metabolism. Science. 2017;358:1051-1055 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2f
Huh H, Lee E, Shin J, Park B, Lee S. STRAP positively regulates TLR3-triggered signaling pathway. Cell Immunol. 2017;318:55-60 pubmed 出版商
  • 免疫沉淀; 人类; 图 5a
Barilari M, Bonfils G, Treins C, Koka V, De Villeneuve D, Fabrega S, et al. ZRF1 is a novel S6 kinase substrate that drives the senescence programme. EMBO J. 2017;36:736-750 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2d
Mooney C, Jimenez Mateos E, Engel T, Mooney C, Diviney M, Venø M, et al. RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis. Sci Rep. 2017;7:41517 pubmed 出版商
  • 免疫印迹; 人类; 图 2e
Ruf S, Heberle A, Langelaar Makkinje M, Gelino S, Wilkinson D, Gerbeth C, et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy. 2017;13:486-505 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2g
Huh H, Ra E, Lee T, Kang S, Park A, Lee E, et al. STRAP Acts as a Scaffolding Protein in Controlling the TLR2/4 Signaling Pathway. Sci Rep. 2016;6:38849 pubmed 出版商
  • 免疫组化; 小鼠; 图 3
Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Koike M, Uchiyama Y, et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Sci Rep. 2016;6:34575 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 3b
Blanco F, Preet R, Aguado A, Vishwakarma V, Stevens L, Vyas A, et al. Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis. Oncotarget. 2016;7:74043-74058 pubmed 出版商
  • 免疫组化; domestic rabbit; 图 4b
  • 免疫印迹; domestic rabbit; 图 3a
Wu A, Xu D, Yang N, Lin S, Chen P, Cala S, et al. Phospholamban is concentrated in the nuclear envelope of cardiomyocytes and involved in perinuclear/nuclear calcium handling. J Mol Cell Cardiol. 2016;100:1-8 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3d
Bartlett J, Trivedi P, Yeung P, Kienesberger P, Pulinilkunnil T. Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy. Biochem J. 2016;473:3769-3789 pubmed
  • 免疫印迹; 人类; 图 6
Nelson D, Jaber Hijazi F, Cole J, Robertson N, Pawlikowski J, Norris K, et al. Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biol. 2016;17:158 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, et al. HIF-1?-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity. Nat Commun. 2016;7:11635 pubmed 出版商
  • 免疫细胞化学; 人类; 表 1
Almeida C, Fernandes S, Ribeiro Junior A, Keith Okamoto O, Vainzof M. Muscle Satellite Cells: Exploring the Basic Biology to Rule Them. Stem Cells Int. 2016;2016:1078686 pubmed 出版商
  • 免疫印迹; 人类; 图 s5
Starokadomskyy P, Gemelli T, Rios J, Xing C, Wang R, Li H, et al. DNA polymerase-? regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol. 2016;17:495-504 pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Stanford E, Wang Z, Novikov O, Mulas F, Landesman Bollag E, Monti S, et al. The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells. BMC Biol. 2016;14:20 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6
Cannavo A, Liccardo D, Eguchi A, Elliott K, Traynham C, Ibetti J, et al. Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases. Nat Commun. 2016;7:10877 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
El Hokayem J, Brittain G, Nawaz Z, Bethea J. Tumor Necrosis Factor Receptor Associated Factors (TRAFs) 2 and 3 Form a Transcriptional Complex with Phosho-RNA Polymerase II and p65 in CD40 Ligand Activated Neuro2a Cells. Mol Neurobiol. 2017;54:1301-1313 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Chen N, Chyau C, Lee Y, Tseng H, Chou F. Promotion of mitotic catastrophe via activation of PTEN by paclitaxel with supplement of mulberry water extract in bladder cancer cells. Sci Rep. 2016;6:20417 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Zhang G, Chan B, Samarina N, Abere B, Weidner Glunde M, Buch A, et al. Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS. Proc Natl Acad Sci U S A. 2016;113:E1034-43 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Lagarrigue S, Lopez Mejia I, Denechaud P, Escoté X, Castillo Armengol J, Jimenez V, et al. CDK4 is an essential insulin effector in adipocytes. J Clin Invest. 2016;126:335-48 pubmed 出版商
Softic S, Gupta M, Wang G, Fujisaka S, O Neill B, Rao T, et al. Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. J Clin Invest. 2017;127:4059-4074 pubmed 出版商
Meng Z, Gong J, Chen Z, Sun J, Xiao Y, Wang L, et al. Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis. Mol Cell. 2017;66:332-344.e4 pubmed 出版商
Marins F, Iddings J, Fontes M, Filosa J. Evidence that remodeling of insular cortex neurovascular unit contributes to hypertension-related sympathoexcitation. Physiol Rep. 2017;5: pubmed 出版商
Lee E, Lee T, Kim J, Park A, Ra E, Kang S, et al. CNBP acts as a key transcriptional regulator of sustained expression of interleukin-6. Nucleic Acids Res. 2017;45:3280-3296 pubmed 出版商
Nyati K, Masuda K, Zaman M, Dubey P, Millrine D, Chalise J, et al. TLR4-induced NF-?B and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a. Nucleic Acids Res. 2017;45:2687-2703 pubmed 出版商
Smith E, Meng Y, Moore R, Tse J, Xu A, Xu X. Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression. BMC Cell Biol. 2017;18:8 pubmed 出版商
Gaston J, Cheradame L, Yvonnet V, Déas O, Poupon M, Judde J, et al. Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents. Oncotarget. 2016;7:77205-77224 pubmed 出版商
Fedoseienko A, Wieringa H, Wisman G, Duiker E, Reyners A, Hofker M, et al. Nuclear COMMD1 Is Associated with Cisplatin Sensitivity in Ovarian Cancer. PLoS ONE. 2016;11:e0165385 pubmed 出版商
George C, Birnie M, Flynn B, Kershaw Y, Lightman S, Conway Campbell B. Ultradian glucocorticoid exposure directs gene-dependent and tissue-specific mRNA expression patterns in vivo. Mol Cell Endocrinol. 2017;439:46-53 pubmed 出版商
Liu R, Khalil H, Lin S, Sargent M, York A, Molkentin J. Nemo-Like Kinase (NLK) Is a Pathological Signaling Effector in the Mouse Heart. PLoS ONE. 2016;11:e0164897 pubmed 出版商
Seo H, Kim H, Kang M, Ryum J, Yi E, Cho J. Identification of the nuclear localisation signal of O-GlcNAc transferase and its nuclear import regulation. Sci Rep. 2016;6:34614 pubmed 出版商
Zhang J, Wang J, Xu J, Lu Y, Jiang J, Wang L, et al. Curcumin targets the TFEB-lysosome pathway for induction of autophagy. Oncotarget. 2016;7:75659-75671 pubmed 出版商
Bouvier C, Macagno N, Nguyen Q, Loundou A, Jiguet Jiglaire C, Gentet J, et al. Prognostic value of the Hippo pathway transcriptional coactivators YAP/TAZ and β1-integrin in conventional osteosarcoma. Oncotarget. 2016;7:64702-64710 pubmed 出版商
Ahmed K, Kren B, Abedin M, Vogel R, Shaughnessy D, Nacusi L, et al. CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors. Oncotarget. 2016;7:61789-61805 pubmed 出版商
Duffy D, Krstic A, Schwarzl T, Halasz M, Iljin K, Fey D, et al. Wnt signalling is a bi-directional vulnerability of cancer cells. Oncotarget. 2016;7:60310-60331 pubmed 出版商
Cavadas M, Mesnieres M, Crifò B, Manresa M, Selfridge A, Keogh C, et al. REST is a hypoxia-responsive transcriptional repressor. Sci Rep. 2016;6:31355 pubmed 出版商
Batalha V, Ferreira D, Coelho J, Valadas J, Gomes R, Temido Ferreira M, et al. The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function. Sci Rep. 2016;6:31493 pubmed 出版商
Nandakumar V, Hansen N, Glenn H, Han J, Helland S, Hernandez K, et al. Vorinostat differentially alters 3D nuclear structure of cancer and non-cancerous esophageal cells. Sci Rep. 2016;6:30593 pubmed 出版商
Suyama K, Silagi E, Choi H, Sakabe K, Mochida J, Shapiro I, et al. Circadian factors BMAL1 and ROR? control HIF-1? transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health. Oncotarget. 2016;7:23056-71 pubmed 出版商
Moiseeva O, Lopes Paciencia S, Huot G, Lessard F, Ferbeyre G. Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase. Aging (Albany NY). 2016;8:366-81 pubmed
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产品信息
SKU号 :
2032S
产品名称 :
核纤层蛋白A/C抗体
规格 :
100微升
Price-(USD) :
235美元
物种x :
H, M, R,(B)
应用 :
免疫组化(石蜡)
产品种类 :
凋亡
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
多克隆抗体
分子量 :
28, 70
宿主 :
靶标 :
核纤层蛋白A/C(全长)
最初蛋白 :
核纤层蛋白A/C
别名 :
70 kDa lamin,CDCD1,CDDC,CMD1A,CMT2B1,EMD2,FPL,FPLD,HGPS,IDC,LDP1,LFP,LGMD1B,LMN1,LMNA,LMNC,Lamin-A/C,PRO1,Renal carcinoma antigen NY-REN-32,lamin A/C
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。