产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
磷酸化EGF受体(Tyr1068)(1H12)小鼠单克隆抗体
目录 :
2236
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
抗原修饰 :
磷酸化
克隆名称 :
1H12
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
文章摘录数: 35
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 人类; 图 2f
Kozlova N, Wottawa M, Katschinski D, Kristiansen G, Kietzmann T. Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer. Oncotarget. 2017;8:9885-9898 pubmed 出版商
  • 免疫印迹; 人类; 图 2f
Im J, Yoon S, Kim B, Ban H, Won K, Chung K, et al. DNA damage induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes ?-catenin-mediated invasion. Biochim Biophys Acta. 2016;1859:1449-1458 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Meng Y, Zheng L, Yang Y, Wang H, Dong J, Wang C, et al. A monoclonal antibody targeting ErbB2 domain III inhibits ErbB2 signaling and suppresses the growth of ErbB2-overexpressing breast tumors. Oncogenesis. 2016;5:e211 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
SaygideÄŸer Kont Y, Minas T, Jones H, Hour S, Çelik H, Temel I, et al. Ezrin Enhances EGFR Signaling and Modulates Erlotinib Sensitivity in Non-Small Cell Lung Cancer Cells. Neoplasia. 2016;18:111-20 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Hennig A, Markwart R, Wolff K, Schubert K, Cui Y, Prior I, et al. Feedback activation of neurofibromin terminates growth factor-induced Ras activation. Cell Commun Signal. 2016;14:5 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Chen J, Chen Y, Yen C, Chen W, Huang W. HBx sensitizes hepatocellular carcinoma cells to lapatinib by up-regulating ErbB3. Oncotarget. 2016;7:473-89 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Safavi S, Järnum S, Vannas C, Udhane S, Jonasson E, Tomić T, et al. HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in vivo. Oncotarget. 2016;7:433-45 pubmed 出版商
  • 免疫印迹; 人类
Kozlova N, Samoylenko A, Drobot L, Kietzmann T. Urokinase is a negative modulator of Egf-dependent proliferation and motility in the two breast cancer cell lines MCF-7 and MDA-MB-231. Mol Carcinog. 2016;55:170-81 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 3
Cecchetti S, Bortolomai I, Ferri R, Mercurio L, Canevari S, Podo F, et al. Inhibition of Phosphatidylcholine-Specific Phospholipase C Interferes with Proliferation and Survival of Tumor Initiating Cells in Squamous Cell Carcinoma. PLoS ONE. 2015;10:e0136120 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
  • 免疫印迹; 人类; 图 5
Valley C, Arndt Jovin D, Karedla N, Steinkamp M, Chizhik A, Hlavacek W, et al. Enhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancer. Mol Biol Cell. 2015;26:4087-99 pubmed 出版商
  • 免疫印迹; 人类
Lin C, Pan C, Wang C, Liu S, Hsiao L, Yang C. Tumor necrosis factor-alpha induces VCAM-1-mediated inflammation via c-Src-dependent transactivation of EGF receptors in human cardiac fibroblasts. J Biomed Sci. 2015;22:53 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Yao X, Wu Y, Zhu M, Qian H, Chen Y. Nitric oxide/cyclic guanosine monophosphate inducers sodium nitroprusside and L-arginine inhibit the proliferation of gastric cancer cells via the activation of type II cyclic guanosine monophosphate-dependent protein kinase. Oncol Lett. 2015;10:479-484 pubmed
  • 免疫印迹; 人类
Teng Y, Radde B, Litchfield L, Ivanova M, Prough R, Clark B, et al. Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells. J Biol Chem. 2015;290:15799-811 pubmed 出版商
  • 免疫印迹; 人类
Chien P, Lin C, Hsiao L, Yang C. c-Src/Pyk2/EGFR/PI3K/Akt/CREB-activated pathway contributes to human cardiomyocyte hypertrophy: Role of COX-2 induction. Mol Cell Endocrinol. 2015;409:59-72 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:400
Isidro R, Cruz M, Isidro A, Baez A, Arroyo A, González Marqués W, et al. Immunohistochemical expression of SP-NK-1R-EGFR pathway and VDR in colonic inflammation and neoplasia. World J Gastroenterol. 2015;21:1749-58 pubmed 出版商
  • 免疫印迹; 人类
Wang J, Mikse O, Liao R, Li Y, Tan L, Jänne P, et al. Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells. Oncogene. 2015;34:2167-77 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Tan L, Wang J, Tanizaki J, Huang Z, Aref A, Rusan M, et al. Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors. Proc Natl Acad Sci U S A. 2014;111:E4869-77 pubmed 出版商
  • 免疫印迹; 人类
De Santis R, Rosi A, Anastasi A, Chiapparino C, Albertoni C, Leoni B, et al. Efficacy of aerosol therapy of lung cancer correlates with EGFR paralysis induced by AvidinOX-anchored biotinylated Cetuximab. Oncotarget. 2014;5:9239-55 pubmed
  • 免疫印迹; 人类
Li L, Wu P, Lee J, Li P, Hsieh W, Ho C, et al. Hinokitiol induces DNA damage and autophagy followed by cell cycle arrest and senescence in gefitinib-resistant lung adenocarcinoma cells. PLoS ONE. 2014;9:e104203 pubmed 出版商
Majorini M, Manenti G, Mano M, De Cecco L, Conti A, Pinciroli P, et al. cIAP1 regulates the EGFR/Snai2 axis in triple-negative breast cancer cells. Cell Death Differ. 2018;25:2147-2164 pubmed 出版商
Cizmecioglu O, Ni J, Xie S, Zhao J, Roberts T. Rac1-mediated membrane raft localization of PI3K/p110? is required for its activation by GPCRs or PTEN loss. elife. 2016;5: pubmed 出版商
van der Mijn J, Sol N, Mellema W, Jimenez C, Piersma S, Dekker H, et al. Analysis of AKT and ERK1/2 protein kinases in extracellular vesicles isolated from blood of patients with cancer. J Extracell Vesicles. 2014;3:25657 pubmed 出版商
Oka S, Uramoto H, Shimokawa H, Yamada S, Tanaka F. Epidermal growth factor receptor-GEP100-Arf6 axis affects the prognosis of lung adenocarcinoma. Oncology. 2014;86:263-70 pubmed 出版商
Loubeau G, Boudra R, Maquaire S, Lours Calet C, Beaudoin C, Verrelle P, et al. NPM1 silencing reduces tumour growth and MAPK signalling in prostate cancer cells. PLoS ONE. 2014;9:e96293 pubmed 出版商
Zhang Z, Dong Z, Lauxen I, Filho M, Nor J. Endothelial cell-secreted EGF induces epithelial to mesenchymal transition and endows head and neck cancer cells with stem-like phenotype. Cancer Res. 2014;74:2869-81 pubmed 出版商
Shin J, Jeong Y, Cho H, Park K, Chung I, Lee I, et al. Melittin suppresses HIF-1?/VEGF expression through inhibition of ERK and mTOR/p70S6K pathway in human cervical carcinoma cells. PLoS ONE. 2013;8:e69380 pubmed 出版商
Di Girolamo N, Atik A, McCluskey P, Wakefield D. Matrix metalloproteinases and their inhibitors in squamous cell carcinoma of the conjunctiva. Ocul Surf. 2013;11:193-205 pubmed 出版商
Keysar S, Astling D, Anderson R, Vogler B, Bowles D, Morton J, et al. A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins. Mol Oncol. 2013;7:776-90 pubmed 出版商
Romanitan M, Näsman A, Munck Wikland E, Dalianis T, Ramqvist T. EGFR and phosphorylated EGFR in relation to HPV and clinical outcome in tonsillar cancer. Anticancer Res. 2013;33:1575-83 pubmed
Liu H, Kato Y, Erzinger S, Kiriakova G, Qian Y, Palmieri D, et al. The role of MMP-1 in breast cancer growth and metastasis to the brain in a xenograft model. BMC Cancer. 2012;12:583 pubmed 出版商
Liu L, Shao X, Gao W, Zhang Z, Liu P, Wang R, et al. MicroRNA-133b inhibits the growth of non-small-cell lung cancer by targeting the epidermal growth factor receptor. FEBS J. 2012;279:3800-12 pubmed 出版商
Ge H, Liu H, Fu Z, Sun Z. Therapeutic and preventive effects of an epidermal growth factor receptor inhibitor on oral squamous cell carcinoma. J Int Med Res. 2012;40:455-66 pubmed
Takaguri A, Kimura K, Hinoki A, Bourne A, Autieri M, Eguchi S. A disintegrin and metalloprotease 17 mediates neointimal hyperplasia in vasculature. Hypertension. 2011;57:841-5 pubmed 出版商
Shao M, Rossi S, Chelladurai B, Shimizu M, Ntukogu O, Ivan M, et al. PDGF induced microRNA alterations in cancer cells. Nucleic Acids Res. 2011;39:4035-47 pubmed 出版商
Peng S, Lai Y, Huang H, Huang H, Huang Y. A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons. Nucleic Acids Res. 2010;38:7446-57 pubmed 出版商
产品信息
SKU号 :
2236S
产品名称 :
磷酸化EGF受体(Tyr1068)(1H12)小鼠单克隆抗体
规格 :
100微升
Price-(USD) :
274美元
物种x :
H, R, Mk
应用 :
免疫组化(石蜡)
产品种类 :
RTK
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
175
宿主 :
小鼠
靶标 :
表皮生长因子受体(Tyr1092)磷酸盐
最初蛋白 :
表皮生长因子受体
别名 :
EGFR,ERBB,ERBB1,Epidermal growth factor receptor,HER1,PIG61,Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1,avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,cell growth inhibiting protein 40,cell proliferation-inducing protein 61,epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian),mENA
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。