出版应用/物种/样本/稀释 | 参考文献 |
---|
| Bott L, Salomons F, Maric D, Liu Y, Merry D, Fischbeck K, et al. The polyglutamine-expanded androgen receptor responsible for spinal and bulbar muscular atrophy inhibits the APC/C(Cdh1) ubiquitin ligase complex. Sci Rep. 2016;6:27703 pubmed 出版商
|
| Titov D, Cracan V, Goodman R, Peng J, Grabarek Z, Mootha V. Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio. Science. 2016;352:231-5 pubmed 出版商
|
- 免疫细胞化学; 人类; 1:1000; 图 7
- 免疫印迹; 人类; 1:1000; 图 2
| Chavali P, Chandrasekaran G, Barr A, Tátrai P, Taylor C, Papachristou E, et al. A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Nat Commun. 2016;7:11005 pubmed 出版商
|
| Nagaoka K, Fujii K, Zhang H, Usuda K, Watanabe G, Ivshina M, et al. CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis. Oncogene. 2016;35:2893-901 pubmed 出版商
|
| Matsuda S, Adachi J, Ihara M, Tanuma N, Shima H, Kakizuka A, et al. Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor. Nucleic Acids Res. 2016;44:636-47 pubmed 出版商
|
| Martinez N, Agosto L, Qiu J, Mallory M, Gazzara M, Barash Y, et al. Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation. Genes Dev. 2015;29:2054-66 pubmed 出版商
|
- 免疫沉淀; 人类; 图 2d
- 免疫印迹; 人类; 图 2d
| Perera R, Stoykova S, Nicolay B, Ross K, Fitamant J, Boukhali M, et al. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature. 2015;524:361-5 pubmed 出版商
|
| Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed 出版商
|
| Cabukusta B, Kol M, Kneller L, Hilderink A, Bickert A, Mina J, et al. ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain. Sci Rep. 2017;7:41290 pubmed 出版商
|
| Tagal V, Wei S, Zhang W, Brekken R, Posner B, Peyton M, et al. SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers. Nat Commun. 2017;8:14098 pubmed 出版商
|
| Yang C, Sengupta S, Hegde P, Mitra J, Jiang S, Holey B, et al. Regulation of oxidized base damage repair by chromatin assembly factor 1 subunit A. Nucleic Acids Res. 2017;45:739-748 pubmed 出版商
|
| Vanhoutte D, Schips T, Kwong J, Davis J, Tjondrokoesoemo A, Brody M, et al. Thrombospondin expression in myofibers stabilizes muscle membranes. elife. 2016;5: pubmed 出版商
|
| Wang Q, Zhang X, Han Y, Wang X, Gao G. M2BP inhibits HIV-1 virion production in a vimentin filaments-dependent manner. Sci Rep. 2016;6:32736 pubmed 出版商
|
| Neubauer H, Pham D, Zebol J, Moretti P, Peterson A, Leclercq T, et al. An oncogenic role for sphingosine kinase 2. Oncotarget. 2016;7:64886-64899 pubmed 出版商
|
| Weaver R, Limzerwala J, Naylor R, Jeganathan K, Baker D, van Deursen J. BubR1 alterations that reinforce mitotic surveillance act against aneuploidy and cancer. elife. 2016;5: pubmed 出版商
|
| Jo Y, Park N, Park S, Kim B, Shin J, Jo D, et al. O-GlcNAcylation of ATG4B positively regulates autophagy by increasing its hydroxylase activity. Oncotarget. 2016;7:57186-57196 pubmed 出版商
|
| Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed 出版商
|
| Wilhelmi I, Kanski R, Neumann A, Herdt O, Hoff F, Jacob R, et al. Sec16 alternative splicing dynamically controls COPII transport efficiency. Nat Commun. 2016;7:12347 pubmed 出版商
|
| Kweon H, Kim D, Bae Y, Park J, Suh B. Acid-Sensing Ion Channel 2a (ASIC2a) Promotes Surface Trafficking of ASIC2b via Heteromeric Assembly. Sci Rep. 2016;6:30684 pubmed 出版商
|
| Wang Y, Sun H, Wang J, Wang H, Meng L, Xu C, et al. DNA-PK-mediated phosphorylation of EZH2 regulates the DNA damage-induced apoptosis to maintain T-cell genomic integrity. Cell Death Dis. 2016;7:e2316 pubmed 出版商
|
| Nakashima H, Ohkawara B, Ishigaki S, Fukudome T, Ito K, Tsushima M, et al. R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr5. Sci Rep. 2016;6:28512 pubmed 出版商
|
| Liu C, Lin S, Hsu H, Yang S, Lin C, Yang M, et al. Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells. Nat Commun. 2016;7:11798 pubmed 出版商
|
| Airik R, Schueler M, Airik M, Cho J, Ulanowicz K, Porath J, et al. SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling. PLoS ONE. 2016;11:e0156081 pubmed 出版商
|
| de Jong P, Taniguchi K, Harris A, Bertin S, Takahashi N, Duong J, et al. ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016;7:11551 pubmed 出版商
|
| Ho T, Guilbaud G, Blow J, Sale J, Watson C. The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability. Cell Rep. 2016;15:724-734 pubmed 出版商
|
| Dreer M, Fertey J, van de Poel S, Straub E, Madlung J, Macek B, et al. Interaction of NCOR/SMRT Repressor Complexes with Papillomavirus E8^E2C Proteins Inhibits Viral Replication. PLoS Pathog. 2016;12:e1005556 pubmed 出版商
|
| Sorber R, Teper Y, Abisoye Ogunniyan A, Waterfall J, Davis S, Killian J, et al. Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion. PLoS ONE. 2016;11:e0149833 pubmed 出版商
|
| Zhao C, Deng Y, Liu L, Yu K, Zhang L, Wang H, et al. Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation. Nat Commun. 2016;7:10883 pubmed 出版商
|
| Kayama T, Mori M, Ito Y, Matsushima T, Nakamichi R, Suzuki H, et al. Gtf2ird1-Dependent Mohawk Expression Regulates Mechanosensing Properties of the Tendon. Mol Cell Biol. 2016;36:1297-309 pubmed 出版商
|
| Boeynaems S, Bogaert E, Michiels E, Gijselinck I, Sieben A, JoviÄić A, et al. Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD. Sci Rep. 2016;6:20877 pubmed 出版商
|
| Lai S, Pelech S. Regulatory roles of conserved phosphorylation sites in the activation T-loop of the MAP kinase ERK1. Mol Biol Cell. 2016;27:1040-50 pubmed 出版商
|
| Zhang Y, Cai R, Zhou R, Li Y, Liu L. Tousled-like kinase mediated a new type of cell death pathway in Drosophila. Cell Death Differ. 2016;23:146-57 pubmed 出版商
|
| Yang B, Zhang M, Gao J, Li J, Fan L, Xiang G, et al. Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer. Oncotarget. 2015;6:37613-25 pubmed 出版商
|
| Xu D, Shan B, Lee B, Zhu K, Zhang T, Sun H, et al. Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system. elife. 2015;4:e10510 pubmed 出版商
|
| Young G, Radhakrishnan V, Centuori S, Gomes C, Martinez J. Comparative analysis of 14-3-3 isoform expression and epigenetic alterations in colorectal cancer. BMC Cancer. 2015;15:826 pubmed 出版商
|
| Xiong Y, Su H, Lv P, Ma Y, Wang S, Miao H, et al. A newly identified berberine derivative induces cancer cell senescence by stabilizing endogenous G-quadruplexes and sparking a DNA damage response at the telomere region. Oncotarget. 2015;6:35625-35 pubmed 出版商
|
| Zulliger R, Conley S, Mwoyosvi M, Stuck M, Azadi S, Naash M. SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting. PLoS ONE. 2015;10:e0138508 pubmed 出版商
|
| Fekrmandi F, Wang T, White J. The hormone-bound vitamin D receptor enhances the FBW7-dependent turnover of NF-κB subunits. Sci Rep. 2015;5:13002 pubmed 出版商
|
| Yarosh C, Tapescu I, Thompson M, Qiu J, Mallory M, Fu X, et al. TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells. Nucleic Acids Res. 2015;43:9006-16 pubmed 出版商
|
| Qin Y, Guo T, Li G, Tang T, Zhao S, Jiao X, et al. CSB-PGBD3 Mutations Cause Premature Ovarian Failure. PLoS Genet. 2015;11:e1005419 pubmed 出版商
|
| Bertoli G, Cava C, Castiglioni I. MicroRNAs: New Biomarkers for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Breast Cancer. Theranostics. 2015;5:1122-43 pubmed 出版商
|
| Golden E, Benito Gonzalez A, Doetzlhofer A. The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci U S A. 2015;112:E3864-73 pubmed 出版商
|
| Wang J, Ma L, Tang X, Zhang X, Qiao Y, Shi Y, et al. Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells. Oncotarget. 2015;6:24075-91 pubmed
|
| Cluxton C, Caffrey B, Kinsella G, Moynagh P, Fares M, Fallon P. Functional conservation of an ancestral Pellino protein in helminth species. Sci Rep. 2015;5:11687 pubmed 出版商
|
| Tang X, Chen X, Xu Y, Qiao Y, Zhang X, Wang Y, et al. CD166 positively regulates MCAM via inhibition to ubiquitin E3 ligases Smurf1 and βTrCP through PI3K/AKT and c-Raf/MEK/ERK signaling in Bel-7402 hepatocellular carcinoma cells. Cell Signal. 2015;27:1694-702 pubmed 出版商
|
| Simões A, Pereira D, Gomes S, Brito H, Carvalho T, French A, et al. Aberrant MEK5/ERK5 signalling contributes to human colon cancer progression via NF-κB activation. Cell Death Dis. 2015;6:e1718 pubmed 出版商
|
| Ikeda M, Ide T, Fujino T, Arai S, Saku K, Kakino T, et al. Overexpression of TFAM or twinkle increases mtDNA copy number and facilitates cardioprotection associated with limited mitochondrial oxidative stress. PLoS ONE. 2015;10:e0119687 pubmed 出版商
|
| Coon B, Baeyens N, Han J, Budatha M, Ross T, Fang J, et al. Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. J Cell Biol. 2015;208:975-86 pubmed 出版商
|
| Popa A, Zhang W, Harrison M, Goodner K, Kazakov T, Goodwin E, et al. Direct binding of retromer to human papillomavirus type 16 minor capsid protein L2 mediates endosome exit during viral infection. PLoS Pathog. 2015;11:e1004699 pubmed 出版商
|
| Mo X, Yang C, Wang X, Burkhardt B, Li Y, Xia H, et al. F3MB(PANDER) decreases mice hepatic triglyceride and is associated with decreased DGAT1 expression. PLoS ONE. 2015;10:e0117156 pubmed 出版商
|
| Hornbeck P, Zhang B, Murray B, Kornhauser J, Latham V, Skrzypek E. PhosphoSitePlus, 2014: mutations, PTMs and recalibrations. Nucleic Acids Res. 2015;43:D512-20 pubmed 出版商
|
| Lin L, Pan S, Zhao J, Liu C, Wang P, Fu L, et al. HSPD1 interacts with IRF3 to facilitate interferon-beta induction. PLoS ONE. 2014;9:e114874 pubmed 出版商
|
| Kim J, Shim M. Prostaglandin F2α receptor (FP) signaling regulates Bmp signaling and promotes chondrocyte differentiation. Biochim Biophys Acta. 2015;1853:500-12 pubmed 出版商
|
| Kim H, Xu H, Yao Q, Li W, Huang Q, Outeda P, et al. Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism. Nat Commun. 2014;5:5482 pubmed 出版商
|
| Zhou L, Yeo A, Ballarano C, Weber U, Allen K, Gilmore T, et al. Disulfide-mediated stabilization of the IκB kinase binding domain of NF-κB essential modulator (NEMO). Biochemistry. 2014;53:7929-44 pubmed 出版商
|
| Duarte L, Young A, Wang Z, Wu H, Panda T, Kou Y, et al. Histone H3.3 and its proteolytically processed form drive a cellular senescence programme. Nat Commun. 2014;5:5210 pubmed 出版商
|
| Ortiz Ruiz M, Ãlvarez Fernández S, Parrott T, Zaknoen S, Burrows F, Ocaña A, et al. Therapeutic potential of ERK5 targeting in triple negative breast cancer. Oncotarget. 2014;5:11308-18 pubmed
|
| Lee S, Seo A, Park B, Jo H, Huh Y. Neuropathic pain model of peripheral neuropathies mediated by mutations of glycyl-tRNA synthetase. J Korean Med Sci. 2014;29:1138-44 pubmed 出版商
|
| Witek M, Snook A, Lin J, Blomain E, Xiang B, Magee M, et al. A novel CDX2 isoform regulates alternative splicing. PLoS ONE. 2014;9:e104293 pubmed 出版商
|
| Izumi H, Kaneko Y. Trim32 facilitates degradation of MYCN on spindle poles and induces asymmetric cell division in human neuroblastoma cells. Cancer Res. 2014;74:5620-30 pubmed 出版商
|
| Huang Y, Bulavin D. Oncogene-mediated regulation of p53 ISGylation and functions. Oncotarget. 2014;5:5808-18 pubmed
|
| Lin T, Chou C, Chung H, Chiang C, Li C, Wu J, et al. Hypoxia-inducible factor 2 alpha is essential for hepatic outgrowth and functions via the regulation of leg1 transcription in the zebrafish embryo. PLoS ONE. 2014;9:e101980 pubmed 出版商
|
| Failler M, Gee H, Krug P, Joo K, Halbritter J, Belkacem L, et al. Mutations of CEP83 cause infantile nephronophthisis and intellectual disability. Am J Hum Genet. 2014;94:905-14 pubmed 出版商
|
| Cross S, Macalinao D, McKie L, Rose L, Kearney A, Rainger J, et al. A dominant-negative mutation of mouse Lmx1b causes glaucoma and is semi-lethal via LDB1-mediated dimerization [corrected]. PLoS Genet. 2014;10:e1004359 pubmed 出版商
|
| Michel M, Wilhelmi I, Schultz A, Preussner M, Heyd F. Activation-induced tumor necrosis factor receptor-associated factor 3 (Traf3) alternative splicing controls the noncanonical nuclear factor ?B pathway and chemokine expression in human T cells. J Biol Chem. 2014;289:13651-60 pubmed 出版商
|
| Zhang X, Ling J, Barcia G, Jing L, Wu J, Barry B, et al. Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures. Am J Hum Genet. 2014;94:547-58 pubmed 出版商
|
| Cimica V, Dalrymple N, Roth E, Nasonov A, Mackow E. An innate immunity-regulating virulence determinant is uniquely encoded by the Andes virus nucleocapsid protein. MBio. 2014;5: pubmed 出版商
|
| Kim S, Rhee K. Importance of the CEP215-pericentrin interaction for centrosome maturation during mitosis. PLoS ONE. 2014;9:e87016 pubmed 出版商
|
| Wolff N, Ghio A, Garrick L, Garrick M, Zhao L, Fenton R, et al. Evidence for mitochondrial localization of divalent metal transporter 1 (DMT1). FASEB J. 2014;28:2134-45 pubmed 出版商
|
| Motta Mena L, Reade A, Mallory M, Glantz S, Weiner O, Lynch K, et al. An optogenetic gene expression system with rapid activation and deactivation kinetics. Nat Chem Biol. 2014;10:196-202 pubmed 出版商
|
| Wang W, Razy Krajka F, Siu E, Ketcham A, Christiaen L. NK4 antagonizes Tbx1/10 to promote cardiac versus pharyngeal muscle fate in the ascidian second heart field. PLoS Biol. 2013;11:e1001725 pubmed 出版商
|
| Lamb T, Vickery J, Bell Pedersen D. Regulation of gene expression in Neurospora crassa with a copper responsive promoter. G3 (Bethesda). 2013;3:2273-80 pubmed 出版商
|
| Thompson R, Vardinogiannis I, Gilmore T. Identification of an NF-?B p50/p65-responsive site in the human MIR155HG promoter. BMC Mol Biol. 2013;14:24 pubmed 出版商
|
| Bujalka H, Koenning M, Jackson S, Perreau V, Pope B, Hay C, et al. MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes. PLoS Biol. 2013;11:e1001625 pubmed 出版商
|
| Ren G, Beech C, Smas C. The immunoglobulin superfamily protein differentiation of embryonic stem cells 1 (dies1) has a regulatory role in preadipocyte to adipocyte conversion. PLoS ONE. 2013;8:e65531 pubmed 出版商
|
| Chaudhuri D, Sancak Y, Mootha V, Clapham D. MCU encodes the pore conducting mitochondrial calcium currents. elife. 2013;2:e00704 pubmed 出版商
|
| Thompson J, Shuttleworth T. How many Orai's does it take to make a CRAC channel?. Sci Rep. 2013;3:1961 pubmed 出版商
|
| Reis A, McCauley J. The influenza virus protein PB1-F2 interacts with IKK? and modulates NF-?B signalling. PLoS ONE. 2013;8:e63852 pubmed 出版商
|
| Cao K, Lailler N, Zhang Y, Kumar A, Uppal K, Liu Z, et al. High-resolution mapping of h1 linker histone variants in embryonic stem cells. PLoS Genet. 2013;9:e1003417 pubmed 出版商
|
| Hlawatsch J, Karlstetter M, Aslanidis A, Lückoff A, Walczak Y, Plank M, et al. Sterile alpha motif containing 7 (samd7) is a novel crx-regulated transcriptional repressor in the retina. PLoS ONE. 2013;8:e60633 pubmed 出版商
|
| El Zaatari M, Kao J, Tessier A, Bai L, Hayes M, Fontaine C, et al. Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets. PLoS ONE. 2013;8:e58935 pubmed 出版商
|
| Shpargel K, Sengoku T, Yokoyama S, Magnuson T. UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development. PLoS Genet. 2012;8:e1002964 pubmed 出版商
|
| Lamers F, Schild L, Koster J, Speleman F, Øra I, Westerhout E, et al. Identification of BIRC6 as a novel intervention target for neuroblastoma therapy. BMC Cancer. 2012;12:285 pubmed 出版商
|
| Schmidt P, Sparrow L, Attwood R, Xiao X, Adams T, McKimm Breschkin J. Taking down the FLAG! How insect cell expression challenges an established tag-system. PLoS ONE. 2012;7:e37779 pubmed 出版商
|
| Choi Y, Sandford G, Nicholas J. Human herpesvirus 8 interferon regulatory factor-mediated BH3-only protein inhibition via Bid BH3-B mimicry. PLoS Pathog. 2012;8:e1002748 pubmed 出版商
|
| Hunkapiller J, Shen Y, Diaz A, Cagney G, McCleary D, Ramalho Santos M, et al. Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal. PLoS Genet. 2012;8:e1002576 pubmed 出版商
|
| Chuang C, Yang D, Bai G, Freeland A, Pruitt S, Schimenti J. Post-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells. Nucleic Acids Res. 2012;40:4914-24 pubmed 出版商
|
| Hornbeck P, Kornhauser J, Tkachev S, Zhang B, Skrzypek E, Murray B, et al. PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse. Nucleic Acids Res. 2012;40:D261-70 pubmed 出版商
|
| Lamb T, Goldsmith C, Bennett L, Finch K, Bell Pedersen D. Direct transcriptional control of a p38 MAPK pathway by the circadian clock in Neurospora crassa. PLoS ONE. 2011;6:e27149 pubmed 出版商
|
| Janas M, Khaled M, Schubert S, Bernstein J, Golan D, Veguilla R, et al. Feed-forward microprocessing and splicing activities at a microRNA-containing intron. PLoS Genet. 2011;7:e1002330 pubmed 出版商
|
| Halder U, Bagchi P, Chattopadhyay S, Dutta D, Chawla Sarkar M. Cell death regulation during influenza A virus infection by matrix (M1) protein: a model of viral control over the cellular survival pathway. Cell Death Dis. 2011;2:e197 pubmed 出版商
|
| Zhao J, Yue W, Zhu M, Du M. AMP-activated protein kinase regulates beta-catenin transcription via histone deacetylase 5. J Biol Chem. 2011;286:16426-34 pubmed 出版商
|
| Forrester M, Eyler C, Rich J. Bacterial flavohemoglobin: a molecular tool to probe mammalian nitric oxide biology. Biotechniques. 2011;50:41-5 pubmed 出版商
|
| Khan M, Vaidya A, Meucci O. CXCL12-mediated regulation of ANP32A/Lanp, a component of the inhibitor of histone acetyl transferase (INHAT) complex, in cortical neurons. J Neuroimmune Pharmacol. 2011;6:163-70 pubmed 出版商
|
| Pfeffer L, Brisson B, Lei H, Barton E. The insulin-like growth factor (IGF)-I E-peptides modulate cell entry of the mature IGF-I protein. Mol Biol Cell. 2009;20:3810-7 pubmed 出版商
|