| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
| Juhasz A, Markel S, Gaur S, Liu H, Lu J, Jiang G, et al. NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction. J Biol Chem. 2017;292:7866-7887 pubmed 出版商 |
| Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed 出版商 |
- 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 6a
| Horsthemke M, Bachg A, Groll K, Moyzio S, Müther B, Hemkemeyer S, et al. Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion. J Biol Chem. 2017;292:7258-7273 pubmed 出版商 |
| Liu Z, Chu S, Yao S, Li Y, Fan S, Sun X, et al. CD74 interacts with CD44 and enhances tumorigenesis and metastasis via RHOA-mediated cofilin phosphorylation in human breast cancer cells. Oncotarget. 2016;7:68303-68313 pubmed 出版商 |
| Wynn M, Yates J, Evans C, Van Wassenhove L, Wu Z, Bridges S, et al. RhoC GTPase Is a Potent Regulator of Glutamine Metabolism and N-Acetylaspartate Production in Inflammatory Breast Cancer Cells. J Biol Chem. 2016;291:13715-29 pubmed 出版商 |
- 免疫组化基因敲除验证; 小鼠; 1:300; 图 s1
| Loebel D, Plageman T, Tang T, Jones V, Muccioli M, Tam P. Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction. Biol Open. 2016;5:130-9 pubmed 出版商 |
| Bowser J, Blackburn M, Shipley G, Molina J, Dunner K, Broaddus R. Loss of CD73-mediated actin polymerization promotes endometrial tumor progression. J Clin Invest. 2016;126:220-38 pubmed 出版商 |
| Shrivastava A, Prasad A, Kuzontkoski P, Yu J, Groopman J. Slit2N Inhibits Transmission of HIV-1 from Dendritic Cells to T-cells by Modulating Novel Cytoskeletal Elements. Sci Rep. 2015;5:16833 pubmed 出版商 |
| Bruurs L, Donker L, Zwakenberg S, Zwartkruis F, Begthel H, Knisely A, et al. ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization. J Cell Biol. 2015;210:1055-63 pubmed 出版商 |
| Bijata M, Wlodarczyk J, Figiel I. Dystroglycan controls dendritic morphogenesis of hippocampal neurons in vitro. Front Cell Neurosci. 2015;9:199 pubmed 出版商 |
| Westcott J, Prechtl A, Maine E, Dang T, Esparza M, Sun H, et al. An epigenetically distinct breast cancer cell subpopulation promotes collective invasion. J Clin Invest. 2015;125:1927-43 pubmed 出版商 |
| Sakamori R, Yu S, Zhang X, Hoffman A, Sun J, Das S, et al. CDC42 inhibition suppresses progression of incipient intestinal tumors. Cancer Res. 2014;74:5480-92 pubmed 出版商 |
| Agabiti S, Li J, Wiemer A. Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation. Cell Death Dis. 2017;8:e2678 pubmed 出版商 |
| Liu H, Huang Y, Liu J, Huang Q. Transcription factor?microRNA synergistic regulatory network revealing the mechanism of polycystic ovary syndrome. Mol Med Rep. 2016;13:3920-8 pubmed 出版商 |
| Pasquier J, Abu Kaoud N, Abdesselem H, Madani A, Hoarau Véchot J, Thawadi H, et al. SDF-1alpha concentration dependent modulation of RhoA and Rac1 modifies breast cancer and stromal cells interaction. BMC Cancer. 2015;15:569 pubmed 出版商 |
| Abraham S, Scarcia M, Bagshaw R, McMahon K, Grant G, Harvey T, et al. A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis. Nat Commun. 2015;6:7286 pubmed 出版商 |
| Humphreys K, McKinnon R, Michael M. miR-18a inhibits CDC42 and plays a tumour suppressor role in colorectal cancer cells. PLoS ONE. 2014;9:e112288 pubmed 出版商 |
| Rohani M, PILCHER B, Chen P, Parks W. Cdc42 inhibits ERK-mediated collagenase-1 (MMP-1) expression in collagen-activated human keratinocytes. J Invest Dermatol. 2014;134:1230-1237 pubmed 出版商 |
| Tang X, Jin R, Qu G, Wang X, Li Z, Yuan Z, et al. GPR116, an adhesion G-protein-coupled receptor, promotes breast cancer metastasis via the G?q-p63RhoGEF-Rho GTPase pathway. Cancer Res. 2013;73:6206-18 pubmed 出版商 |
| Jung J, Oh J, Lee D, Lee S, Chung J. Blood type B antigen modulates cell migration through regulating cdc42 expression and activity in HaCaT cells. J Cell Physiol. 2013;228:2243-51 pubmed 出版商 |
| Shin J, Krey J, Hassan A, Metlagel Z, Tauscher A, Pagana J, et al. Molecular architecture of the chick vestibular hair bundle. Nat Neurosci. 2013;16:365-74 pubmed 出版商 |
