产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
磷酸化血管内皮生长因子受体2(Tyr1175)(19A10)兔单克隆抗体
目录 :
2478
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
19A10
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-冰冻切片
文章摘录数: 50
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:500; 图 3c
Harde E, Nicholson L, Furones Cuadrado B, Bissen D, Wigge S, Urban S, et al. EphrinB2 regulates VEGFR2 during dendritogenesis and hippocampal circuitry development. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Luck R, Urban S, Karakatsani A, Harde E, Sambandan S, Nicholson L, et al. VEGF/VEGFR2 signaling regulates hippocampal axon branching during development. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 图 s4t
Xu M, Xu H, Lin Y, Sun X, Wang L, Fang Z, et al. LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis. Cell. 2019;178:1478-1492.e20 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3c
Park M, Kim A, Manandhar S, Oh S, Jang G, Kang L, et al. CCN1 interlinks integrin and hippo pathway to autoregulate tip cell activity. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 3g
Genet G, Boyé K, Mathivet T, Ola R, Zhang F, Dubrac A, et al. Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis. Nat Commun. 2019;10:2350 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 8b
  • 免疫印迹; 人类; 1:2000; 图 8a
Zhang S, Liu W, Yang Y, Sun K, Li S, Xu H, et al. Tmem30a Deficiency in endothelial cells impairs cell proliferation and angiogenesis. J Cell Sci. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2d
Segarra M, Aburto M, Cop F, Llaó Cid C, Härtl R, Damm M, et al. Endothelial Dab1 signaling orchestrates neuro-glia-vessel communication in the central nervous system. Science. 2018;361: pubmed 出版商
  • 免疫印迹; 小鼠; 图 s6o
Das A, Huang G, Bonkowski M, Longchamp A, Li C, Schultz M, et al. Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging. Cell. 2018;173:74-89.e20 pubmed 出版商
  • 免疫印迹; 人类; 图 8c
Kim J, Kim Y, Kim J, Park D, Bae H, Lee D, et al. YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation. J Clin Invest. 2017;127:3441-3461 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 10b
Kilpatrick L, Friedman Ohana R, Alcobia D, Riching K, Peach C, Wheal A, et al. Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexes. Biochem Pharmacol. 2017;136:62-75 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2a
Yang G, Zhao Z, Qin T, Wang D, Chen L, Xiang R, et al. TNFSF15 inhibits VEGF-stimulated vascular hyperpermeability by inducing VEGFR2 dephosphorylation. FASEB J. 2017;31:2001-2012 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Wu Q, Ma Y, Ruan C, Yang Y, Liu X, Ge Q, et al. Loss of osteoglycin promotes angiogenesis in limb ischaemia mouse models via modulation of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 signalling pathway. Cardiovasc Res. 2017;113:70-80 pubmed 出版商
  • 免疫印迹; 人类; 图 s7c
  • 免疫印迹; 小鼠; 图 3i
Lee S, Rho S, Park H, Park J, Kim J, Lee I, et al. Carbohydrate-binding protein CLEC14A regulates VEGFR-2- and VEGFR-3-dependent signals during angiogenesis and lymphangiogenesis. J Clin Invest. 2017;127:457-471 pubmed 出版商
  • 免疫印迹; 人类; 图 s1
Xin H, ZHONG C, Nudleman E, Ferrara N. Evidence for Pro-angiogenic Functions of VEGF-Ax. Cell. 2016;167:275-284.e6 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Fearnley G, Smith G, Abdul Zani I, Yuldasheva N, Mughal N, Homer Vanniasinkam S, et al. VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis. Biol Open. 2016;5:571-83 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Nishida Fukuda H, Araki R, Shudou M, Okazaki H, Tomono Y, Nakayama H, et al. Ectodomain Shedding of Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE-1) Is Induced by Vascular Endothelial Growth Factor A (VEGF-A). J Biol Chem. 2016;291:10490-500 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Zhang Z, Zhang H, Peng T, Li D, Xu J. Melittin suppresses cathepsin S-induced invasion and angiogenesis via blocking of the VEGF-A/VEGFR-2/MEK1/ERK1/2 pathway in human hepatocellular carcinoma. Oncol Lett. 2016;11:610-618 pubmed
  • 免疫印迹; 人类; 1:1000
Ulrich F, Carretero Ortega J, Menendez J, Narvaez C, Sun B, Lancaster E, et al. Reck enables cerebrovascular development by promoting canonical Wnt signaling. Development. 2016;143:147-59 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Zhao C, Su Y, Zhang J, Feng Q, Qu L, Wang L, et al. Fibrinogen-derived fibrinostatin inhibits tumor growth through anti-angiogenesis. Cancer Sci. 2015;106:1596-606 pubmed 出版商
  • 免疫印迹; 小鼠
Suzuki Y, Nagai N, Yamakawa K, Muranaka Y, Hokamura K, Umemura K. Recombinant tissue-type plasminogen activator transiently enhances blood-brain barrier permeability during cerebral ischemia through vascular endothelial growth factor-mediated endothelial endocytosis in mice. J Cereb Blood Flow Metab. 2015;35:2021-31 pubmed 出版商
  • 免疫印迹; 小鼠
Andersson L, Scharin Täng M, Lundqvist A, Lindbom M, Mardani I, Fogelstrand P, et al. Rip2 modifies VEGF-induced signalling and vascular permeability in myocardial ischaemia. Cardiovasc Res. 2015;107:478-86 pubmed 出版商
  • 免疫印迹; 人类
Kim B, Lee J, Choi J, Park D, Song H, Park T, et al. Imidazole-based alkaloid derivative LCB54-0009 suppresses ocular angiogenesis and lymphangiogenesis in models of experimental retinopathy and corneal neovascularization. Br J Pharmacol. 2015;172:3875-89 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Khayati F, Pérez Cano L, Maouche K, Sadoux A, Boutalbi Z, Podgorniak M, et al. EMMPRIN/CD147 is a novel coreceptor of VEGFR-2 mediating its activation by VEGF. Oncotarget. 2015;6:9766-80 pubmed
  • 免疫印迹; 人类; 1:1000; 图 5e
Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, et al. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun. 2015;6:6576 pubmed 出版商
  • 免疫印迹; 人类
Coon B, Baeyens N, Han J, Budatha M, Ross T, Fang J, et al. Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. J Cell Biol. 2015;208:975-86 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5e
Choi S, Lee H, Choi J, Kim J, Park C, Joo H, et al. Cyclosporin A induces cardiac differentiation but inhibits hemato-endothelial differentiation of P19 cells. PLoS ONE. 2015;10:e0117410 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 5
Scotti L, Abramovich D, Pascuali N, Irusta G, Meresman G, Tesone M, et al. Local VEGF inhibition prevents ovarian alterations associated with ovarian hyperstimulation syndrome. J Steroid Biochem Mol Biol. 2014;144 Pt B:392-401 pubmed 出版商
  • 免疫印迹; 人类
Chen P, Qin L, Zhuang Z, Tellides G, Lax I, Schlessinger J, et al. The docking protein FRS2? is a critical regulator of VEGF receptors signaling. Proc Natl Acad Sci U S A. 2014;111:5514-9 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
Chatterjee S, Wang Y, Duncan M, Naik U. Junctional adhesion molecule-A regulates vascular endothelial growth factor receptor-2 signaling-dependent mouse corneal wound healing. PLoS ONE. 2013;8:e63674 pubmed 出版商
  • 免疫印迹; 人类
Rapraeger A, Ell B, Roy M, Li X, Morrison O, Thomas G, et al. Vascular endothelial-cadherin stimulates syndecan-1-coupled insulin-like growth factor-1 receptor and cross-talk between ?V?3 integrin and vascular endothelial growth factor receptor 2 at the onset of endothelial cell dissemination during angiogenesi. FEBS J. 2013;280:2194-206 pubmed 出版商
Balaji Ragunathrao V, Anwar M, Akhter M, Chavez A, Mao D, Natarajan V, et al. Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling. Cell Rep. 2019;29:3472-3487.e4 pubmed 出版商
Njah K, Chakraborty S, Qiu B, Arumugam S, Raju A, Pobbati A, et al. A Role of Agrin in Maintaining the Stability of Vascular Endothelial Growth Factor Receptor-2 during Tumor Angiogenesis. Cell Rep. 2019;28:949-965.e7 pubmed 出版商
Ikeuchi T, de Vega S, Forcinito P, Doyle A, Amaral J, Rodriguez I, et al. Extracellular Protein Fibulin-7 and Its C-Terminal Fragment Have In Vivo Antiangiogenic Activity. Sci Rep. 2018;8:17654 pubmed 出版商
Oladipupo S, Kabir A, Smith C, Choi K, Ornitz D. Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1). Sci Rep. 2018;8:14724 pubmed 出版商
Yan M, Turgeon P, Man H, Dubinsky M, Ho J, El Rass S, et al. Histone acetyltransferase 7 (KAT7)-dependent intragenic histone acetylation regulates endothelial cell gene regulation. J Biol Chem. 2018;293:4381-4402 pubmed 出版商
Busceti C, Marchitti S, Bianchi F, Di Pietro P, Riozzi B, Stanzione R, et al. Dickkopf-3 Upregulates VEGF in Cultured Human Endothelial Cells by Activating Activin Receptor-Like Kinase 1 (ALK1) Pathway. Front Pharmacol. 2017;8:111 pubmed 出版商
Zopf D, Fichtner I, Bhargava A, Steinke W, Thierauch K, Diefenbach K, et al. Pharmacologic activity and pharmacokinetics of metabolites of regorafenib in preclinical models. Cancer Med. 2016;5:3176-3185 pubmed 出版商
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Sun Q, Zhou J, Zhang Z, Guo M, Liang J, Zhou F, et al. Discovery of fruquintinib, a potent and highly selective small molecule inhibitor of VEGFR 1, 2, 3 tyrosine kinases for cancer therapy. Cancer Biol Ther. 2014;15:1635-45 pubmed 出版商
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产品信息
SKU号 :
2478S
产品名称 :
磷酸化血管内皮生长因子受体2(Tyr1175)(19A10)兔单克隆抗体
规格 :
100微升
Price-(USD) :
274美元
物种x :
H, M
应用 :
免疫荧光(免疫细胞化学)
产品种类 :
RTK
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
230
宿主 :
靶标 :
VEGFR2(Tyr1175)磷酸盐
最初蛋白 :
VEGFR-2
别名 :
CD309,FLK-1,FLK1,Fetal liver kinase 1,KDR,Kinase insert domain receptor,Protein-tyrosine kinase receptor flk-1,VEGFR,VEGFR-2,VEGFR2,VGFR2,Vascular endothelial growth factor receptor 2,fetal liver kinase-1,kinase insert domain receptor (a type III receptor tyrosine kinase),soluble VEGFR2,tyrosine kinase growth factor receptor
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。