产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
p53(7F5)兔单克隆抗体
目录 :
2527
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
7F5
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫印迹基因敲除验证
文章摘录数: 51
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:500; 图 7a
Phan T, Paliogiannis P, Nasrallah G, Giordo R, Eid A, Fois A, et al. Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis. Cell Mol Life Sci. 2021;78:2031-2057 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 7a
Cheng X, Zhang Y, Song F, Song F, Gao C, Liang X, et al. URM1 Promoted Tumor Growth and Suppressed Apoptosis via the JNK Signaling Pathway in Hepatocellular Carcinoma. Onco Targets Ther. 2020;13:8011-8025 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1b, 3b
Chen Y, Liu Z, Wang Y, Zhuang J, Peng Y, Mo X, et al. FKBP51 induces p53-dependent apoptosis and enhances drug sensitivity of human non-small-cell lung cancer cells. Exp Ther Med. 2020;19:2236-2242 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 s18
  • 免疫细胞化学; 人类; 1:200; 图 s8, s9, s10
  • 免疫印迹; 人类; 1:1000; 图 3d
Meng X, Zhao Y, Han B, Zha C, Zhang Y, Li Z, et al. Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways. Nat Commun. 2020;11:594 pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Hou N, He X, Yang Y, Fu J, Zhang W, Guo Z, et al. TRPV1 Induced Apoptosis of Colorectal Cancer Cells by Activating Calcineurin-NFAT2-p53 Signaling Pathway. Biomed Res Int. 2019;2019:6712536 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6b
Liang C, Ma Y, Yong L, Yang C, Wang P, Liu X, et al. Y-box binding protein-1 promotes tumorigenesis and progression via the epidermal growth factor receptor/AKT pathway in spinal chordoma. Cancer Sci. 2019;110:166-179 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 s1b
  • 免疫印迹; 人类; 图 s1c
Park J, Lee J, Sheu K, Wang L, Balanis N, Nguyen K, et al. Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage. Science. 2018;362:91-95 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s8a
Zhu B, Chen S, Wang H, Yin C, Han C, Peng C, et al. The protective role of DOT1L in UV-induced melanomagenesis. Nat Commun. 2018;9:259 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4b
Lang M, Jenkins S, Balzano P, Owoyele A, Patel A, Bamezai A. Engaging Ly-6A/Sca-1 triggers lipid raft-dependent and -independent responses in CD4+ T-cell lines. Immun Inflamm Dis. 2017;5:448-460 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 7f
  • 免疫印迹; 人类; 1:1000; 图 6e
Patel N, Garikapati K, Pandita R, Singh D, Pandita T, Bhadra U, et al. miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin. Sci Rep. 2017;7:4263 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2c
Daley D, Mani V, Mohan N, Akkad N, Ochi A, Heindel D, et al. Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance. Nat Med. 2017;23:556-567 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1d
Parrales A, Ranjan A, Iyer S, Padhye S, Weir S, Roy A, et al. DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway. Nat Cell Biol. 2016;18:1233-1243 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Ma T, Fan B, Zhang C, Zhao H, Han C, Gao C, et al. Metabonomics applied in exploring the antitumour mechanism of physapubenolide on hepatocellular carcinoma cells by targeting glycolysis through the Akt-p53 pathway. Sci Rep. 2016;6:29926 pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Grassi M, Palma C, Thomé C, Lanfredi G, Poersch A, Faça V. Proteomic analysis of ovarian cancer cells during epithelial-mesenchymal transition (EMT) induced by epidermal growth factor (EGF) reveals mechanisms of cell cycle control. J Proteomics. 2017;151:2-11 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1600; 图 4b
Cesnekova J, Spáčilová J, Hansikova H, Houstek J, Zeman J, Stiburek L. LACE1 interacts with p53 and mediates its mitochondrial translocation and apoptosis. Oncotarget. 2016;7:47687-47698 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Chesnokova V, Zonis S, Zhou C, Recouvreux M, Ben Shlomo A, Araki T, et al. Growth hormone is permissive for neoplastic colon growth. Proc Natl Acad Sci U S A. 2016;113:E3250-9 pubmed 出版商
  • 免疫组化; 人类; 1:500; 图 3a
D Brot A, Kurtz P, Regan E, Jakubowski B, Abrams J. A platform for interrogating cancer-associated p53 alleles. Oncogene. 2017;36:286-291 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Chernova T, Sun X, Powley I, Galavotti S, Grosso S, Murphy F, et al. Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease. Cell Death Differ. 2016;23:1152-64 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 2a
Guo W, Zhang Y, Ling Z, Liu X, Zhao X, Yuan Z, et al. Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner. Cell Death Dis. 2015;6:e1919 pubmed 出版商
  • 免疫组化; 人类; 1:200; 图 s18
Ohashi A, Ohori M, Iwai K, Nakayama Y, Nambu T, Morishita D, et al. Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells. Nat Commun. 2015;6:7668 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s5
Yang K, Kohler R, Landon M, Giedt R, Weissleder R. Single cell resolution in vivo imaging of DNA damage following PARP inhibition. Sci Rep. 2015;5:10129 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 5a
Wang J, Guo W, Zhou H, Luo N, Nie C, Zhao X, et al. Mitochondrial p53 phosphorylation induces Bak-mediated and caspase-independent cell death. Oncotarget. 2015;6:17192-205 pubmed
  • 免疫细胞化学; 小鼠; 图 5
  • 免疫印迹; 小鼠; 图 5
Zhang W, Hou J, Wang X, Jiang R, Yin Y, Ji J, et al. PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis. Oncotarget. 2015;6:9420-33 pubmed
  • 免疫组化; 人类; 1:200; 图 1
  • 免疫印迹; 人类; 1:1000; 图 2
Wang H, Bao W, Jiang F, Che Q, Chen Z, Wang F, et al. Mutant p53 (p53-R248Q) functions as an oncogene in promoting endometrial cancer by up-regulating REGγ. Cancer Lett. 2015;360:269-79 pubmed 出版商
  • 免疫细胞化学; 人类
Peltonen K, Colis L, Liu H, Jäämaa S, Zhang Z, Af Hällström T, et al. Small molecule BMH-compounds that inhibit RNA polymerase I and cause nucleolar stress. Mol Cancer Ther. 2014;13:2537-46 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5i
Cao J, Lu Y, Qi J, An G, Mao Z, Jia H, et al. MiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells. Cell Death Dis. 2014;5:e1426 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Brohl A, Solomon D, Chang W, Wang J, Song Y, Sindiri S, et al. The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation. PLoS Genet. 2014;10:e1004475 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Moriarity B, Rahrmann E, Beckmann D, Conboy C, Watson A, Carlson D, et al. Simple and efficient methods for enrichment and isolation of endonuclease modified cells. PLoS ONE. 2014;9:e96114 pubmed 出版商
Ramamonjisoa N, Ackerstaff E. Characterization of the Tumor Microenvironment and Tumor-Stroma Interaction by Non-invasive Preclinical Imaging. Front Oncol. 2017;7:3 pubmed 出版商
Milewski D, Pradhan A, Wang X, Cai Y, Le T, Turpin B, et al. FoxF1 and FoxF2 transcription factors synergistically promote rhabdomyosarcoma carcinogenesis by repressing transcription of p21Cip1 CDK inhibitor. Oncogene. 2017;36:850-862 pubmed 出版商
Zhang Q, Ma S, Liu B, Liu J, Zhu R, Li M. Chrysin induces cell apoptosis via activation of the p53/Bcl-2/caspase-9 pathway in hepatocellular carcinoma cells. Exp Ther Med. 2016;12:469-474 pubmed
Dai W, Miao H, Fang S, Fang T, Chen N, Li M. CDKN3 expression is negatively associated with pathological tumor stage and CDKN3 inhibition promotes cell survival in hepatocellular carcinoma. Mol Med Rep. 2016;14:1509-14 pubmed 出版商
Piccolo S, Hoffman L, Conner T, Shrestha G, Cohen A, Marks J, et al. Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility. Mol Syst Biol. 2016;12:860 pubmed 出版商
Zhai H, Hu S, Liu T, Wang F, Wang X, Wu G, et al. Nitidine chloride inhibits proliferation and induces apoptosis in colorectal cancer cells by suppressing the ERK signaling pathway. Mol Med Rep. 2016;13:2536-42 pubmed 出版商
Wang Z. Transactivation of Epidermal Growth Factor Receptor by G Protein-Coupled Receptors: Recent Progress, Challenges and Future Research. Int J Mol Sci. 2016;17: pubmed 出版商
Kim S, Park S, Shim S, Park S, Kim K, Jeong S, et al. Bay 61-3606 Sensitizes TRAIL-Induced Apoptosis by Downregulating Mcl-1 in Breast Cancer Cells. PLoS ONE. 2015;10:e0146073 pubmed 出版商
Zhang H, Zhan C, Ke J, Xue Z, Zhang A, Xu K, et al. EGFR kinase domain mutation positive lung cancers are sensitive to intrapleural perfusion with hyperthermic chemotherapy (IPHC) complete treatment. Oncotarget. 2016;7:3367-78 pubmed 出版商
Thorenoor N, Faltejskova Vychytilova P, Hombach S, Mlcochova J, Kretz M, Svoboda M, et al. Long non-coding RNA ZFAS1 interacts with CDK1 and is involved in p53-dependent cell cycle control and apoptosis in colorectal cancer. Oncotarget. 2016;7:622-37 pubmed 出版商
Ho D, Kim H, Kim J, Sim H, Ahn H, Kim J, et al. Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression. Mol Brain. 2015;8:54 pubmed 出版商
Mendham A, Duffield R, Coutts A, Marino F, Boyko A, Bishop D. Rugby-specific small-sided games training is an effective alternative to stationary cycling at reducing clinical risk factors associated with the development of type 2 diabetes: a randomized, controlled trial. PLoS ONE. 2015;10:e0127548 pubmed 出版商
Unno K, Ono M, Winder A, Maniar K, Paintal A, Yu Y, et al. Establishment of human patient-derived endometrial cancer xenografts in NOD scid gamma mice for the study of invasion and metastasis. PLoS ONE. 2014;9:e116064 pubmed 出版商
Huang C, Chuang C, Shu W, Chang C, Chen C, Fan T, et al. Distinct epidermal keratinocytes respond to extremely low-frequency electromagnetic fields differently. PLoS ONE. 2014;9:e113424 pubmed 出版商
Khan S, Ebeling M, Zaman M, Sikander M, Yallapu M, Chauhan N, et al. MicroRNA-145 targets MUC13 and suppresses growth and invasion of pancreatic cancer. Oncotarget. 2014;5:7599-609 pubmed
Bassères D, Ebbs A, Cogswell P, Baldwin A. IKK is a therapeutic target in KRAS-Induced lung cancer with disrupted p53 activity. Genes Cancer. 2014;5:41-55 pubmed
Ludwig L, Gazda H, Eng J, Eichhorn S, Thiru P, Ghazvinian R, et al. Altered translation of GATA1 in Diamond-Blackfan anemia. Nat Med. 2014;20:748-53 pubmed 出版商
Zhu Y, Zhou Y, Shi J. Post-slippage multinucleation renders cytotoxic variation in anti-mitotic drugs that target the microtubules or mitotic spindle. Cell Cycle. 2014;13:1756-64 pubmed 出版商
Sobral L, Sousa L, Coletta R, Cabral H, Greene L, Tajara E, et al. Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models. Mol Cancer. 2014;13:32 pubmed 出版商
Sato K. Cellular functions regulated by phosphorylation of EGFR on Tyr845. Int J Mol Sci. 2013;14:10761-90 pubmed 出版商
Cheung M, Pei J, Pei Y, Jhanwar S, Pass H, Testa J. The promyelocytic leukemia zinc-finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival. Oncogene. 2010;29:1633-40 pubmed 出版商
Kumar N, Basundra R, Maiti S. Elevated polyamines induce c-MYC overexpression by perturbing quadruplex-WC duplex equilibrium. Nucleic Acids Res. 2009;37:3321-31 pubmed 出版商
产品信息
SKU号 :
2527S
产品名称 :
p53(7F5)兔单克隆抗体
规格 :
100微升
Price-(USD) :
235美元
物种x :
H, Mk
应用 :
染色质免疫沉淀
产品种类 :
细胞周期/节律点控制
运输温度 :
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
53
宿主 :
靶标 :
p53
最初蛋白 :
p53
别名 :
Antigen NY-CO-13,Cellular tumor antigen p53,FLJ92943,LFS1,P53,Phosphoprotein p53,TP53,TRP53,Tumor suppressor p53,p53 antigen,p53 transformation suppressor,p53 tumor suppressor,transformation-related protein 53,tumor protein p53
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。