产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
p53(1C12)小鼠单克隆抗体(Alexa Fluor系列荧光染料®647共轭标签)
目录 :
2533
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
AF647
克隆名称 :
1C12
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪
文章摘录数: 64
出版应用/物种/样品/稀释参考文献
  • 流式细胞仪; 小鼠; 图 e6a
Garaycoechea J, Crossan G, Langevin F, Mulderrig L, Louzada S, Yang F, et al. Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. Nature. 2018;553:171-177 pubmed 出版商
  • 流式细胞仪; 人类; 图 s2a
Liu T, Krysiak K, Shirai C, Kim S, Shao J, Ndonwi M, et al. Knockdown of HSPA9 induces TP53-dependent apoptosis in human hematopoietic progenitor cells. PLoS ONE. 2017;12:e0170470 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Vermeer D, Coppock J, Zeng E, Lee K, Spanos W, Onken M, et al. Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis. Oncotarget. 2016;7:24194-207 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2
Goh A, Xue Y, Leushacke M, Li L, Wong J, Chiam P, et al. Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice. Oncotarget. 2015;6:17968-80 pubmed
  • 免疫印迹; 人类; 图 8
Zhang M, Xu E, Zhang J, Chen X. PPM1D phosphatase, a target of p53 and RBM38 RNA-binding protein, inhibits p53 mRNA translation via dephosphorylation of RBM38. Oncogene. 2015;34:5900-11 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Xu Y, Swartz K, Siu K, Bhattacharyya M, Minella A. Fbw7-dependent cyclin E regulation ensures terminal maturation of bone marrow erythroid cells by restraining oxidative metabolism. Oncogene. 2014;33:3161-71 pubmed 出版商
Sifford J, Stahl J, Salinas E, Forrest J. Murine Gammaherpesvirus 68 LANA and SOX Homologs Counteract ATM-Driven p53 Activity during Lytic Viral Replication. J Virol. 2015;90:2571-85 pubmed 出版商
Keskin N, Deniz E, Eryilmaz J, Un M, Batur T, Ersahin T, et al. PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function. Mol Cell Biol. 2015;35:1741-53 pubmed 出版商
Lu K, Fang X, Feng L, Jiang Y, Zhou X, Liu X, et al. The STAT3 inhibitor WP1066 reverses the resistance of chronic lymphocytic leukemia cells to histone deacetylase inhibitors induced by interleukin-6. Cancer Lett. 2015;359:250-8 pubmed 出版商
Mo J, Alam K, Kang I, Park W, Seo G, Choi S, et al. MicroRNA 196B regulates FAS-mediated apoptosis in colorectal cancer cells. Oncotarget. 2015;6:2843-55 pubmed
Kitagawa M, Shiozaki A, Ichikawa D, Nakashima S, Kosuga T, Konishi H, et al. Tumor necrosis factor-α-induced apoptosis of gastric cancer MKN28 cells: accelerated degradation of the inhibitor of apoptosis family members. Arch Biochem Biophys. 2015;566:43-8 pubmed 出版商
Lawhorn I, Ferreira J, Wang C. Evaluation of sgRNA target sites for CRISPR-mediated repression of TP53. PLoS ONE. 2014;9:e113232 pubmed 出版商
Kusama K, Yoshie M, Tamura K, Imakawa K, Tachikawa E. EPAC2-mediated calreticulin regulates LIF and COX2 expression in human endometrial glandular cells. J Mol Endocrinol. 2015;54:17-24 pubmed 出版商
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Huang E, Wang F, Chen Y, Chen Y, Wang C, Lin I, et al. Amifostine alleviates radiation-induced lethal small bowel damage via promotion of 14-3-3σ-mediated nuclear p53 accumulation. Oncotarget. 2014;5:9756-69 pubmed
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Siu K, Xu Y, Swartz K, Bhattacharyya M, Gurbuxani S, Hua Y, et al. Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation. Mol Cell Biol. 2014;34:3244-58 pubmed 出版商
Lee H, Kwon M, Lee S, Hall R, Yun C, Choi I. Systematic family-wide analysis of sodium bicarbonate cotransporter NBCn1/SLC4A7 interactions with PDZ scaffold proteins. Physiol Rep. 2014;2: pubmed 出版商
Lin X, Yi Z, Diao J, Shao M, Zhao L, Cai H, et al. ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition. J Transl Med. 2014;12:105 pubmed 出版商
Villa Morales M, Cobos M, González Gugel E, Alvarez Iglesias V, Martinez B, Piris M, et al. FAS system deregulation in T-cell lymphoblastic lymphoma. Cell Death Dis. 2014;5:e1110 pubmed 出版商
Hung N, Chen Y, Taha A, Olivecrona M, Boet R, Wiles A, et al. Increased paired box transcription factor 8 has a survival function in glioma. BMC Cancer. 2014;14:159 pubmed 出版商
Cantarella G, Di Benedetto G, Ribatti D, Saccani Jotti G, Bernardini R. Involvement of caspase 8 and c-FLIPL in the proangiogenic effects of the tumour necrosis factor-related apoptosis-inducing ligand (TRAIL). FEBS J. 2014;281:1505-13 pubmed 出版商
Bhat H, Baba R, Adams M, Khanday F. Role of SNTA1 in Rac1 activation, modulation of ROS generation, and migratory potential of human breast cancer cells. Br J Cancer. 2014;110:706-14 pubmed 出版商
Edeleva E, Shcherbata H. Stress-induced ECM alteration modulates cellular microRNAs that feedback to readjust the extracellular environment and cell behavior. Front Genet. 2013;4:305 pubmed 出版商
Li Z, Zhao C, Li Z, Zhao Y, Shan S, Shi T, et al. Reconstructed mung bean trypsin inhibitor targeting cell surface GRP78 induces apoptosis and inhibits tumor growth in colorectal cancer. Int J Biochem Cell Biol. 2014;47:68-75 pubmed 出版商
Guo M, Cao Y, Wang T, Song X, Liu Z, Zhou E, et al. Baicalin inhibits Staphylococcus aureus-induced apoptosis by regulating TLR2 and TLR2-related apoptotic factors in the mouse mammary glands. Eur J Pharmacol. 2014;723:481-8 pubmed 出版商
Kusama K, Yoshie M, Tamura K, Nakayama T, Nishi H, Isaka K, et al. The role of exchange protein directly activated by cyclic AMP 2-mediated calreticulin expression in the decidualization of human endometrial stromal cells. Endocrinology. 2014;155:240-8 pubmed 出版商
Wang S, Huang J, Lyu H, Cai B, Yang X, Li F, et al. Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer. Breast Cancer Res. 2013;15:R101 pubmed
Kawashima H, Takatori H, Suzuki K, Iwata A, Yokota M, Suto A, et al. Tumor suppressor p53 inhibits systemic autoimmune diseases by inducing regulatory T cells. J Immunol. 2013;191:3614-23 pubmed 出版商
Kim C, Tambe Y, Mukaisho K, Sugihara H, Isono T, Sonoda H, et al. Female-specific rectal carcinogenesis in cyclin D1b transgenic mice. Carcinogenesis. 2014;35:227-36 pubmed 出版商
Chen Y, Kamili A, Hardy J, Groblewski G, Khanna K, Byrne J. Tumor protein D52 represents a negative regulator of ATM protein levels. Cell Cycle. 2013;12:3083-97 pubmed 出版商
van Dijk M, Halpin McCormick A, Sessler T, Samali A, Szegezdi E. Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways. Cell Death Dis. 2013;4:e702 pubmed 出版商
Gillissen B, Richter A, Overkamp T, Essmann F, Hemmati P, Preissner R, et al. Targeted therapy of the XIAP/proteasome pathway overcomes TRAIL-resistance in carcinoma by switching apoptosis signaling to a Bax/Bak-independent 'type I' mode. Cell Death Dis. 2013;4:e643 pubmed 出版商
Sung M, Giannakakou P. BRCA1 regulates microtubule dynamics and taxane-induced apoptotic cell signaling. Oncogene. 2014;33:1418-28 pubmed 出版商
Ganapathy S, Xiao S, Seo S, Lall R, Yang M, Xu T, et al. Low-dose arsenic induces chemotherapy protection via p53/NF-?B-mediated metabolic regulation. Oncogene. 2014;33:1359-66 pubmed 出版商
Burgeiro A, Bento A, Gajate C, Oliveira P, Mollinedo F. Rapid human melanoma cell death induced by sanguinarine through oxidative stress. Eur J Pharmacol. 2013;705:109-18 pubmed 出版商
Sistrunk C, Kim S, Wang X, Lee S, Kim Y, Macias E, et al. Skp2 deficiency inhibits chemical skin tumorigenesis independent of p27(Kip1) accumulation. Am J Pathol. 2013;182:1854-64 pubmed 出版商
Gaud G, Guillemot D, Jacob Y, Favre M, Vuillier F. EVER2 protein binds TRADD to promote TNF-?-induced apoptosis. Cell Death Dis. 2013;4:e499 pubmed 出版商
Wu Y, Zhang Y, Wang M, Li Q, Qu Z, Shi V, et al. Downregulation of HER3 by a novel antisense oligonucleotide, EZN-3920, improves the antitumor activity of EGFR and HER2 tyrosine kinase inhibitors in animal models. Mol Cancer Ther. 2013;12:427-37 pubmed 出版商
Faccenda D, Tan C, Seraphim A, Duchen M, Campanella M. IF1 limits the apoptotic-signalling cascade by preventing mitochondrial remodelling. Cell Death Differ. 2013;20:686-97 pubmed 出版商
Vyas R, Kumar R, Clermont F, Helfricht A, Kalev P, Sotiropoulou P, et al. RNF4 is required for DNA double-strand break repair in vivo. Cell Death Differ. 2013;20:490-502 pubmed 出版商
Kolb R, Greer P, Cao P, Cowan K, Yan Y. ERK1/2 signaling plays an important role in topoisomerase II poison-induced G2/M checkpoint activation. PLoS ONE. 2012;7:e50281 pubmed 出版商
Hao J, Jin W, Li X, Wang S, Zhang X, Fan H, et al. Inhibition of alpha interferon (IFN-?)-induced microRNA-122 negatively affects the anti-hepatitis B virus efficiency of IFN-?. J Virol. 2013;87:137-47 pubmed 出版商
Termén S, Tan E, Heldin C, Moustakas A. p53 regulates epithelial-mesenchymal transition induced by transforming growth factor ?. J Cell Physiol. 2013;228:801-13 pubmed 出版商
Förster A, Falcone F, Gibbs B, Preussner L, Fiebig B, Altunok H, et al. Anti-Fas/CD95 and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) differentially regulate apoptosis in normal and neoplastic human basophils. Leuk Lymphoma. 2013;54:835-42 pubmed 出版商
Miura Y, Sakurai Y, Endo T. O-GlcNAc modification affects the ATM-mediated DNA damage response. Biochim Biophys Acta. 2012;1820:1678-85 pubmed 出版商
Kusio Kobialka M, Wolanin K, Podszywalow Bartnicka P, Sikora E, Skowronek K, McKenna S, et al. Increased acetylation of lysine 317/320 of p53 caused by BCR-ABL protects from cytoplasmic translocation of p53 and mitochondria-dependent apoptosis in response to DNA damage. Apoptosis. 2012;17:950-63 pubmed 出版商
Paunovic V, Carter N, Thalhamer T, Blair D, Gordon B, Lacey E, et al. Immune complex-mediated co-ligation of the BCR with Fc?RIIB results in homeostatic apoptosis of B cells involving Fas signalling that is defective in the MRL/Lpr model of systemic lupus erythematosus. J Autoimmun. 2012;39:332-46 pubmed 出版商
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Li J, Zhang K, Meng W, Yang Y. Tanshinone IIA in acute promyelocytic leukemia. Am J Med Sci. 2012;344:283-8 pubmed
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Bartucci M, Svensson S, Romania P, Dattilo R, Patrizii M, Signore M, et al. Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy. Cell Death Differ. 2012;19:768-78 pubmed 出版商
Garimella S, Rocca A, Lipkowitz S. WEE1 inhibition sensitizes basal breast cancer cells to TRAIL-induced apoptosis. Mol Cancer Res. 2012;10:75-85 pubmed 出版商
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Nishimoto N, Arai S, Ichikawa M, Nakagawa M, Goyama S, Kumano K, et al. Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through down-regulation of p19ARF. Blood. 2011;118:2541-50 pubmed 出版商
产品信息
SKU号 :
2533S
产品名称 :
p53(1C12)小鼠单克隆抗体(Alexa Fluor系列荧光染料®647共轭标签)
规格 :
100微升
Price-(USD) :
291美元
物种x :
H, M, R, Mk
应用 :
流式细胞仪
产品种类 :
细胞周期/节律点控制
运输温度 :
储存温度 :
4°C
产品类型 :
单克隆抗体
宿主 :
小鼠
靶标 :
p53
最初蛋白 :
p53
别名 :
Antigen NY-CO-13,Cellular tumor antigen p53,FLJ92943,LFS1,P53,Phosphoprotein p53,TP53,TRP53,Tumor suppressor p53,p53 antigen,p53 transformation suppressor,p53 tumor suppressor,transformation-related protein 53,tumor protein p53
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。