公司名称 :
产品类型 :
产品名称 :
目录 :
克隆性 :
宿主 :
domestic rabbit
共轭标签 :
反应物种 :
African green monkey, 人类, 小鼠, brown rat, bantam,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
文章摘录数: 131
  • 免疫印迹; 小鼠; 1:200; 图 4e
di Meco A, Pratico D. Early-life exposure to high-fat diet influences brain health in aging mice. Aging Cell. 2019;18:e13040 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Grossmann D, Berenguer Escuder C, Bellet M, Scheibner D, Bohler J, Massart F, et al. Mutations in RHOT1 Disrupt Endoplasmic Reticulum-Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's Disease. Antioxid Redox Signal. 2019;31:1213-1234 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 2b
Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, et al. Autophagy regulates lipid metabolism through selective turnover of NCoR1. Nat Commun. 2019;10:1567 pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Zhang J, He J, Johnson J, Rahman F, Gavathiotis E, Cuervo A, et al. Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells. Front Endocrinol (Lausanne). 2019;10:21 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1d
Chao H, Lin C, Zuo Q, Liu Y, Xiao M, Xu X, et al. Cardiolipin-Dependent Mitophagy Guides Outcome after Traumatic Brain Injury. J Neurosci. 2019;39:1930-1943 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5e
Gallot Y, Bohnert K, Straughn A, Xiong G, Hindi S, Kumar A. PERK regulates skeletal muscle mass and contractile function in adult mice. FASEB J. 2019;33:1946-1962 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Cheruiyot A, Li S, Nickless A, Roth R, Fitzpatrick J, You Z. Compound C inhibits nonsense-mediated RNA decay independently of AMPK. PLoS ONE. 2018;13:e0204978 pubmed 出版商
  • 免疫印迹; 人类; 图 s6a
Song K, Kim J, Lee Y, Bae H, Lee H, Woo S, et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018;128:4098-4114 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 6f
Pajares M, Rojo A, Arias E, Díaz Carretero A, Cuervo A, Cuadrado A. Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A. Autophagy. 2018;14:1310-1322 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s3a
Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nat Cell Biol. 2018;20:823-835 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1e
Perot B, Boussier J, Yatim N, Rossman J, Ingersoll M, Albert M. Autophagy diminishes the early interferon-? response to influenza A virus resulting in differential expression of interferon-stimulated genes. Cell Death Dis. 2018;9:539 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 5h
  • 免疫印迹; 人类; 1:1000; 图 5a
Lee S, Bazick H, Chittoor Vinod V, Al Salihi M, Xia G, Notterpek L. Elevated Peripheral Myelin Protein 22, Reduced Mitotic Potential, and Proteasome Impairment in Dermal Fibroblasts from Charcot-Marie-Tooth Disease Type 1A Patients. Am J Pathol. 2018;188:728-738 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s7b
  • 免疫印迹; 人类; 图 5a
Ni Z, HE J, Wu Y, Hu C, Dai X, Yan X, et al. AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells. Autophagy. 2018;14:685-701 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 4g
Bansal M, Moharir S, Sailasree S, Sirohi K, Sudhakar C, Sarathi D, et al. Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein. J Biol Chem. 2018;293:132-147 pubmed 出版商
  • 免疫细胞化学; 人类; 1:300; 图 s4e
Tseng J, Xie L, Song S, Xie Y, Allen L, Ajit D, et al. The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology. Cell Rep. 2017;20:2169-2183 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1f
Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, et al. Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6. Oncotarget. 2017;8:47890-47901 pubmed 出版商
  • 免疫印迹; 人类; 1:1500; 图 1b
Sakamaki J, Wilkinson S, Hahn M, Tasdemir N, O Prey J, Clark W, et al. Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function. Mol Cell. 2017;66:517-532.e9 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Nayar U, Sadek J, Reichel J, Hernandez Hopkins D, Akar G, Barelli P, et al. Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies. J Clin Invest. 2017;127:2066-2080 pubmed 出版商
  • 流式细胞仪; 人类; 图 10c
Banerjee B, Koner D, Lal P, Saha N. Unique mitochondrial localization of arginase 1 and 2 in hepatocytes of air-breathing walking catfish, Clarias batrachus and their differential expression patterns under hyper-ammonia stress. Gene. 2017;622:13-22 pubmed 出版商
  • 免疫印迹; African green monkey; 图 9a
  • 免疫印迹; 小鼠; 图 5a
Kaufman D, Papillon J, Larose L, Iwawaki T, Cybulsky A. Deletion of inositol-requiring enzyme-1? in podocytes disrupts glomerular capillary integrity and autophagy. Mol Biol Cell. 2017;28:1636-1651 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 s8a
Kang H, Park J, Choi K, Kim Y, Choi H, Jung C, et al. Chemical screening identifies ATM as a target for alleviating senescence. Nat Chem Biol. 2017;13:616-623 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6e
Fajardo V, Gamu D, Mitchell A, Bloemberg D, Bombardier E, Chambers P, et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS ONE. 2017;12:e0173708 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7a
  • 免疫印迹; 人类; 1:1000; 图 1d
Kovacs T, Billes V, Komlos M, Hotzi B, Manzéger A, Tarnóci A, et al. The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms. Sci Rep. 2017;7:42014 pubmed 出版商
  • 免疫印迹; 人类; 图 2b
Wolfson R, Chantranupong L, Wyant G, Gu X, Orozco J, Shen K, et al. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. 2017;543:438-442 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1a
  • 免疫印迹; 人类; 图 1s1g
Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 6b
  • 免疫印迹; 小鼠; 1:2000; 图 6a
  • 免疫印迹; 人类; 1:2000; 图 1a
Chen S, Jing Y, Kang X, Yang L, Wang D, Zhang W, et al. Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy. Nucleic Acids Res. 2017;45:1144-1158 pubmed 出版商
  • 免疫沉淀; 牛; 图 6a
  • 免疫印迹; 牛; 1:1000; 图 5a
Russo V, Inglese C, Avallone L, Roperto F, Abate C, Zizzo N, et al. Sigma 2 receptor expression levels in blood and bladder from healthy and bladder cancer cattle. Vet Comp Oncol. 2017;15:1503-1512 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 4b
  • 免疫印迹; 小鼠; 图 4a
Ma K, Fu W, Tang M, Zhang C, Hou T, Li R, et al. PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment. Autophagy. 2017;13:579-591 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Ruf S, Heberle A, Langelaar Makkinje M, Gelino S, Wilkinson D, Gerbeth C, et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy. 2017;13:486-505 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:200; 图 5c
Borgia D, Malena A, Spinazzi M, Desbats M, Salviati L, Russell A, et al. Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients. Hum Mol Genet. 2017;26:1087-1103 pubmed 出版商
  • 免疫组化; 人类; 图 7b
  • 免疫印迹; 人类; 图 5j
  • 免疫印迹; 小鼠; 图 5a
Pietrocola F, Demont Y, Castoldi F, Enot D, Durand S, Semeraro M, et al. Metabolic effects of fasting on human and mouse blood in vivo. Autophagy. 2017;13:567-578 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2b
  • 免疫印迹; 人类; 图 2a
Capizzi M, Strappazzon F, Cianfanelli V, Papaleo E, Cecconi F. MIR7-3HG, a MYC-dependent modulator of cell proliferation, inhibits autophagy by a regulatory loop involving AMBRA1. Autophagy. 2017;13:554-566 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5a
Laporte A, Barrott J, Yao R, Poulin N, Brodin B, Jones K, et al. HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma. PLoS ONE. 2017;12:e0169407 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 8a
Yeung P, Lai A, Son H, Zhang X, Hwang O, Chung S, et al. Aldose reductase deficiency leads to oxidative stress-induced dopaminergic neuronal loss and autophagic abnormality in an animal model of Parkinson's disease. Neurobiol Aging. 2017;50:119-133 pubmed 出版商
  • 免疫组化; 小鼠; 图 6c
  • 免疫印迹; 小鼠; 图 6e
  • 免疫印迹; 人类; 图 6e
Da Ros M, Lehtiniemi T, Olotu O, Fischer D, Zhang F, Vihinen H, et al. FYCO1 and autophagy control the integrity of the haploid male germ cell-specific RNP granules. Autophagy. 2017;13:302-321 pubmed 出版商
  • 免疫印迹; 人类; 图 2f
Cramer S, Saha A, Liu J, Tadi S, Tiziani S, Yan W, et al. Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth. Nat Med. 2017;23:120-127 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
  • 免疫印迹; brown rat; 图 3d
Li J, Chen T, Xiao M, Li N, Wang S, Su H, et al. Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1. Oncotarget. 2016;7:86648-86659 pubmed 出版商
  • 免疫细胞化学; African green monkey; 图 6b
  • 免疫细胞化学; 人类; 图 6a
Tábara L, Escalante R. VMP1 Establishes ER-Microdomains that Regulate Membrane Contact Sites and Autophagy. PLoS ONE. 2016;11:e0166499 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3d
Sakata K, Araki K, Nakano H, Nishina T, Komazawa Sakon S, Murai S, et al. Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome. Sci Rep. 2016;6:37200 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s4j
Cao L, Riascos Bernal D, Chinnasamy P, Dunaway C, Hou R, Pujato M, et al. Control of mitochondrial function and cell growth by the atypical cadherin Fat1. Nature. 2016;539:575-578 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5f
  • 免疫印迹; 小鼠; 图 1b
Han J, Bae J, Choi C, Choi S, Kang H, Jo E, et al. Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice. Autophagy. 2016;12:2326-2343 pubmed
  • 免疫印迹; 小鼠
Liu L, Tao Z, Zheng L, Brooke J, Smith C, Liu D, et al. FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytes. Cell Death Discov. 2016;2:16066 pubmed
  • 免疫细胞化学; 人类; 1:400; 图 5
  • 免疫印迹; 人类; 1:400; 图 5
Wang H, Chen S, Lo W. Identification of Cofilin-1 Induces G0/G1 Arrest and Autophagy in Angiotensin-(1-7)-treated Human Aortic Endothelial Cells from iTRAQ Quantitative Proteomics. Sci Rep. 2016;6:35372 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
Figueroa González G, García Castillo V, Coronel Hernández J, López Urrutia E, León Cabrera S, Arias Romero L, et al. Anti-inflammatory and Antitumor Activity of a Triple Therapy for a Colitis-Related Colorectal Cancer. J Cancer. 2016;7:1632-1644 pubmed
  • 免疫细胞化学; 人类; 图 3c
  • 免疫印迹; 人类; 1:1000; 图 3f
Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1g
Hubert V, Peschel A, Langer B, Groger M, Rees A, Kain R. LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes. Biol Open. 2016;5:1516-1529 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Heulot M, Chevalier N, Puyal J, Margue C, Michel S, Kreis S, et al. The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner. Oncotarget. 2016;7:64342-64359 pubmed 出版商
  • 免疫组化; 小鼠; 图 3c
  • 免疫印迹; 小鼠; 图 3b
Conlon D, Thomas T, Fedotova T, Hernandez Ono A, Di Paolo G, Chan R, et al. Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis. J Clin Invest. 2016;126:3852-3867 pubmed 出版商
  • 免疫印迹; brown rat; 图 2
Ogasawara R, Fujita S, Hornberger T, Kitaoka Y, Makanae Y, Nakazato K, et al. The role of mTOR signalling in the regulation of skeletal muscle mass in a rodent model of resistance exercise. Sci Rep. 2016;6:31142 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 2
  • 免疫印迹; 人类; 图 4
Xu S, Law B, Mok S, Leung E, Fan X, Coghi P, et al. Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol. Int J Oncol. 2016;49:1576-88 pubmed 出版商
  • 流式细胞仪; 人类; 图 5c
  • 免疫印迹; 人类; 图 5b
Xing Y, Cao R, Hu H. TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles). Cell Death Dis. 2016;7:e2322 pubmed 出版商
  • 免疫印迹; brown rat; 图 4c
Bartlett J, Trivedi P, Yeung P, Kienesberger P, Pulinilkunnil T. Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy. Biochem J. 2016;473:3769-3789 pubmed
  • 免疫细胞化学; 小鼠; 图 2d
  • 免疫印迹; 小鼠; 图 1b
  • 免疫印迹; 人类; 图 1a
Wang J, Zhou J, Kho D, Reiners J, Wu G. Role for DUSP1 (dual-specificity protein phosphatase 1) in the regulation of autophagy. Autophagy. 2016;12:1791-1803 pubmed
  • 免疫组化-自由浮动切片; 小鼠; 1:250; 图 3j
  • 免疫组化-石蜡切片; 小鼠; 1:250; 图 3j
  • 免疫印迹; 小鼠; 1:2000; 图 2g
Pajares M, Jiménez Moreno N, García Yagüe A, Escoll M, De Ceballos M, Van Leuven F, et al. Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes. Autophagy. 2016;12:1902-1916 pubmed
  • 免疫印迹; 小鼠; 图 1c
Pan H, Zhong X, Lee S. Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasis. BMC Biochem. 2016;17:14 pubmed 出版商
  • 免疫细胞化学; brown rat; 图 8d
Bramini M, Sacchetti S, Armirotti A, Rocchi A, Vazquez E, León Castellanos V, et al. Graphene Oxide Nanosheets Disrupt Lipid Composition, Ca(2+) Homeostasis, and Synaptic Transmission in Primary Cortical Neurons. ACS Nano. 2016;10:7154-71 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3
  • 免疫印迹; 小鼠; 图 3
Hamlin A, Basford J, Jaeschke A, Hui D. LRP1 Protein Deficiency Exacerbates Palmitate-induced Steatosis and Toxicity in Hepatocytes. J Biol Chem. 2016;291:16610-9 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1c
Shin H, Kim H, Oh S, Lee J, Kee M, Ko H, et al. AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy. Nature. 2016;534:553-7 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 4
  • 免疫印迹; 小鼠; 图 s1
Gómez Sánchez R, Yakhine Diop S, Bravo San Pedro J, Pizarro Estrella E, Rodríguez Arribas M, Climent V, et al. PINK1 deficiency enhances autophagy and mitophagy induction. Mol Cell Oncol. 2016;3:e1046579 pubmed 出版商
  • 免疫印迹; 小鼠; 图 8
Foltz S, Luan J, Call J, Patel A, Peissig K, Fortunato M, et al. Four-week rapamycin treatment improves muscular dystrophy in a fukutin-deficient mouse model of dystroglycanopathy. Skelet Muscle. 2016;6:20 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Elimam H, Papillon J, Kaufman D, Guillemette J, Aoudjit L, Gross R, et al. Genetic Ablation of Calcium-independent Phospholipase A2? Induces Glomerular Injury in Mice. J Biol Chem. 2016;291:14468-82 pubmed 出版商
  • 免疫印迹; bantam; 图 7
Droubi A, Bulley S, Clarke J, Irvine R. Nuclear localizations of phosphatidylinositol 5-phosphate 4-kinases ? and ? are dynamic and independently regulated during starvation-induced stress. Biochem J. 2016;473:2155-63 pubmed 出版商
  • 免疫印迹; 人类; 图 s1
Karvela M, Baquero P, Kuntz E, Mukhopadhyay A, Mitchell R, Allan E, et al. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells. Autophagy. 2016;12:936-48 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
Ting W, Yang J, Kuo C, Xiao Z, Lu X, Yeh Y, et al. Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts. Oncotarget. 2016;7:39017-39025 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 2
De Filippis L, Halikere A, McGowan H, Moore J, Tischfield J, Hart R, et al. Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells. Mol Brain. 2016;9:51 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Onesto E, Colombrita C, Gumina V, Borghi M, Dusi S, Doretti A, et al. Gene-specific mitochondria dysfunctions in human TARDBP and C9ORF72 fibroblasts. Acta Neuropathol Commun. 2016;4:47 pubmed 出版商
  • 免疫印迹; 人类; 图 s5b
Swiader A, Nahapetyan H, Faccini J, D Angelo R, Mucher E, Elbaz M, et al. Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids. Oncotarget. 2016;7:28821-35 pubmed 出版商
  • 免疫组化; brown rat; 图 4
  • 免疫印迹; brown rat; 1:1000; 图 3
Lai C, Tsai C, Kuo W, Ho T, Day C, Pai P, et al. Multi-Strain Probiotics Inhibit Cardiac Myopathies and Autophagy to Prevent Heart Injury in High-Fat Diet-Fed Rats. Int J Med Sci. 2016;13:277-85 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Dey A, Mustafi S, Saha S, Kumar Dhar Dwivedi S, Mukherjee P, Bhattacharya R. Inhibition of BMI1 induces autophagy-mediated necroptosis. Autophagy. 2016;12:659-70 pubmed 出版商
  • 免疫印迹; 人类; 图 7c
Park J, Jung C, Seo M, Otto N, Grunwald D, Kim K, et al. The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14. Autophagy. 2016;12:547-64 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Phelps Polirer K, Abt M, Smith D, Yeh E. Co-Targeting of JNK and HUNK in Resistant HER2-Positive Breast Cancer. PLoS ONE. 2016;11:e0153025 pubmed 出版商
  • 免疫印迹; 人类; 图 6c
Lin T, Chang Y, Lee S, Campbell M, Wang T, Shen S, et al. REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling. Oncotarget. 2016;7:26137-51 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 表 1
Krishnan V, White Z, McMahon C, Hodgetts S, Fitzgerald M, Shavlakadze T, et al. A Neurogenic Perspective of Sarcopenia: Time Course Study of Sciatic Nerves From Aging Mice. J Neuropathol Exp Neurol. 2016;75:464-78 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s1e
Prieto J, León M, Ponsoda X, Sendra R, Bort R, Ferrer Lorente R, et al. Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming. Nat Commun. 2016;7:11124 pubmed 出版商
  • 免疫印迹; 牛; 图 3a
Xia X, Che Y, Gao Y, Zhao S, Ao C, Yang H, et al. Arginine Supplementation Recovered the IFN-?-Mediated Decrease in Milk Protein and Fat Synthesis by Inhibiting the GCN2/eIF2? Pathway, Which Induces Autophagy in Primary Bovine Mammary Epithelial Cells. Mol Cells. 2016;39:410-7 pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Chen S, Wang C, Yeo S, Liang C, Okamoto T, Sun S, et al. Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model. Genes Dev. 2016;30:856-69 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
Jennewein L, Ronellenfitsch M, Antonietti P, Ilina E, Jung J, Stadel D, et al. Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas. Oncotarget. 2016;7:20016-32 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Yu L, Wu W, Gu C, Zhong D, Zhao X, Kong Y, et al. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells. Oncotarget. 2016;7:14693-707 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 4
  • 免疫印迹; 小鼠; 图 4
Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, et al. EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016;6:396-410 pubmed 出版商
  • 免疫印迹; 小鼠; 图 10a
Cao L, Qin X, Peterson M, Haller S, Wilson K, Hu N, et al. CARD9 knockout ameliorates myocardial dysfunction associated with high fat diet-induced obesity. J Mol Cell Cardiol. 2016;92:185-95 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Lei Y, Kansy B, Li J, Cong L, Liu Y, Trivedi S, et al. EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complex. Oncogene. 2016;35:4698-707 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 2
  • 免疫印迹; 人类; 1:500; 图 2
Kim N, Kim M, Sung P, Bae Y, Shin E, Yoo J. Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A. Nat Commun. 2016;7:10631 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1
Ruiz A, Rockfield S, Taran N, Haller E, Engelman R, Flores I, et al. Effect of hydroxychloroquine and characterization of autophagy in a mouse model of endometriosis. Cell Death Dis. 2016;7:e2059 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 图 s16
Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, et al. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease. Nat Commun. 2016;7:10332 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2
Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy. 2016;12:410-23 pubmed 出版商
  • 免疫印迹; 小鼠; 图 9
Wang Y, Xu S, Xu W, Yang H, Hu P, Li Y. Sodium formate induces autophagy and apoptosis via the JNK signaling pathway of photoreceptor cells. Mol Med Rep. 2016;13:1111-8 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Huang Y, Chen Y, Lai Y, Cheng C, Lin T, Su Y, et al. Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitro. Int J Mol Med. 2016;37:83-91 pubmed 出版商
  • 免疫印迹; brown rat; 1:500; 图 2
Lesmana R, Sinha R, Singh B, Zhou J, Ohba K, Wu Y, et al. Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. Endocrinology. 2016;157:23-38 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
Alnasser H, Guan Q, Zhang F, Gleave M, Nguan C, Du C. Requirement of clusterin expression for prosurvival autophagy in hypoxic kidney tubular epithelial cells. Am J Physiol Renal Physiol. 2016;310:F160-73 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Ivankovic D, Chau K, Schapira A, Gegg M. Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy. J Neurochem. 2016;136:388-402 pubmed 出版商
  • 免疫印迹; 人类; 图 2f
van Geldermalsen M, Wang Q, Nagarajah R, Marshall A, Thoeng A, Gao D, et al. ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer. Oncogene. 2016;35:3201-8 pubmed 出版商
Weng L, Han Y, Enomoto A, Kitaura Y, Nagamori S, Kanai Y, et al. Negative regulation of amino acid signaling by MAPK-regulated 4F2hc/Girdin complex. PLoS Biol. 2018;16:e2005090 pubmed 出版商
Nwadike C, Williamson L, Gallagher L, Guan J, Chan E. AMPK Inhibits ULK1-Dependent Autophagosome Formation and Lysosomal Acidification via Distinct Mechanisms. Mol Cell Biol. 2018;38: pubmed 出版商
Rockfield S, Flores I, Nanjundan M. Expression and function of nuclear receptor coactivator 4 isoforms in transformed endometriotic and malignant ovarian cells. Oncotarget. 2018;9:5344-5367 pubmed 出版商
Sun P, Zhang S, Qin X, Chang X, Cui X, Li H, et al. Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1. Autophagy. 2018;14:336-346 pubmed 出版商
Le Guerroué F, Eck F, Jung J, Starzetz T, Mittelbronn M, Kaulich M, et al. Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway. Mol Cell. 2017;68:786-796.e6 pubmed 出版商
Gallagher L, Radhi O, Abdullah M, McCluskey A, Boyd M, Chan E. Lysosomotropism depends on glucose: a chloroquine resistance mechanism. Cell Death Dis. 2017;8:e3014 pubmed 出版商
Sun G, Guzman E, Balasanyan V, Conner C, Wong K, Zhou H, et al. A molecular signature for anastasis, recovery from the brink of apoptotic cell death. J Cell Biol. 2017;216:3355-3368 pubmed 出版商
Zhu S, Ding S, Wang P, Wei Z, Pan W, Palm N, et al. Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells. Nature. 2017;546:667-670 pubmed 出版商
Kim T, Shin Y, Lee H, Kim J, Choe J, Jang J, et al. Ohmyungsamycins promote antimicrobial responses through autophagy activation via AMP-activated protein kinase pathway. Sci Rep. 2017;7:3431 pubmed 出版商
Sahu S, Kumar M, Chakraborty S, Banerjee S, Kumar R, Gupta P, et al. MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection. PLoS Pathog. 2017;13:e1006410 pubmed 出版商
Lampada A, O Prey J, Szabadkai G, Ryan K, Hochhauser D, Salomoni P. mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism. Cell Death Differ. 2017;24:1045-1062 pubmed 出版商
Yan J, Hedl M, Abraham C. An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes. J Clin Invest. 2017;127:2192-2205 pubmed 出版商
Gomes L, Menck C, Cuervo A. Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation. Autophagy. 2017;13:928-940 pubmed 出版商
Yang A, Pantoom S, Wu Y. Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins. elife. 2017;6: pubmed 出版商
Giusto M, Barberi L, Di Sario F, Rizzuto E, Nicoletti C, Ascenzi F, et al. Skeletal muscle myopenia in mice model of bile duct ligation and carbon tetrachloride-induced liver cirrhosis. Physiol Rep. 2017;5: pubmed 出版商
Tavera Mendoza L, Westerling T, Libby E, Marusyk A, Cato L, Cassani R, et al. Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells. Proc Natl Acad Sci U S A. 2017;114:E2186-E2194 pubmed 出版商
Hayes H, Peterson B, Haldeman J, Newgard C, Hohmeier H, Stephens S. Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival. PLoS ONE. 2017;12:e0172567 pubmed 出版商
Manna D, Pust S, Torgersen M, Cordara G, Kunzler M, Krengel U, et al. Polyporus squamosus Lectin 1a (PSL1a) Exhibits Cytotoxicity in Mammalian Cells by Disruption of Focal Adhesions, Inhibition of Protein Synthesis and Induction of Apoptosis. PLoS ONE. 2017;12:e0170716 pubmed 出版商
Diamanti M, Gupta J, Bennecke M, De Oliveira T, Ramakrishnan M, Braczynski A, et al. IKK? controls ATG16L1 degradation to prevent ER stress during inflammation. J Exp Med. 2017;214:423-437 pubmed 出版商
Kozlova N, Wottawa M, Katschinski D, Kristiansen G, Kietzmann T. Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer. Oncotarget. 2017;8:9885-9898 pubmed 出版商
Sinha R, Singh B, Zhou J, Xie S, Farah B, Lesmana R, et al. Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells. Autophagy. 2017;13:169-186 pubmed 出版商
Rojansky R, Cha M, Chan D. Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1. elife. 2016;5: pubmed 出版商
Yalamanchili N, Kriete A, Alfego D, Danowski K, Kari C, Rodeck U. Distinct Cell Stress Responses Induced by ATP Restriction in Quiescent Human Fibroblasts. Front Genet. 2016;7:171 pubmed
Huang M, Garcia J, Thomas D, Zhu L, Nguyen L, Chan S, et al. Autophagy mediates proteolysis of NPM1 and HEXIM1 and sensitivity to BET inhibition in AML cells. Oncotarget. 2016;7:74917-74930 pubmed 出版商
Moosavi M, Sharifi M, Ghafary S, Mohammadalipour Z, Khataee A, Rahmati M, et al. Photodynamic N-TiO2 Nanoparticle Treatment Induces Controlled ROS-mediated Autophagy and Terminal Differentiation of Leukemia Cells. Sci Rep. 2016;6:34413 pubmed 出版商
Rovithi M, de Haas R, Honeywell R, Poel D, Peters G, Griffioen A, et al. Alternative scheduling of pulsatile, high dose sunitinib efficiently suppresses tumor growth. J Exp Clin Cancer Res. 2016;35:138 pubmed 出版商
Guo X, Sun X, Hu D, Wang Y, Fujioka H, Vyas R, et al. VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease. Nat Commun. 2016;7:12646 pubmed 出版商
Devkota S, Jeong H, Kim Y, Ali M, Roh J, Hwang D, et al. Functional characterization of EI24-induced autophagy in the degradation of RING-domain E3 ligases. Autophagy. 2016;12:2038-2053 pubmed
Sakata Y, Okamoto T, Oshio K, Nakamura H, Iwamoto H, Namba K, et al. Dietary supplementation with shiikuwasha extract attenuates dexamethasone-induced skeletal muscle atrophy in aged rats. Springerplus. 2016;5:816 pubmed 出版商
Fernández B, Fdez E, Gomez Suaga P, Gil F, Molina Villalba I, Ferrer I, et al. Iron overload causes endolysosomal deficits modulated by NAADP-regulated 2-pore channels and RAB7A. Autophagy. 2016;12:1487-506 pubmed 出版商
Sanongkiet S, Ponnikorn S, Udomsangpetch R, Tungpradabkul S. Burkholderia pseudomallei rpoS mediates iNOS suppression in human hepatocyte (HC04) cells. FEMS Microbiol Lett. 2016;363: pubmed 出版商
Bettoun A, Joffre C, Zago G, Surdez D, Vallerand D, Gundogdu R, et al. Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation. Oncotarget. 2016;7:44142-44160 pubmed 出版商
Pellegrini P, Dyczynski M, Sbrana F, Karlgren M, Buoncervello M, Hägg Olofsson M, et al. Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cells. Oncotarget. 2016;7:35703-35723 pubmed 出版商
Ra E, Lee T, Won Kim S, Park A, Choi H, Jang I, et al. TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells. Nat Commun. 2016;7:11726 pubmed 出版商
Yeo S, Itahana Y, Guo A, Han R, Iwamoto K, Nguyen H, et al. Transglutaminase 2 contributes to a TP53-induced autophagy program to prevent oncogenic transformation. elife. 2016;5:e07101 pubmed 出版商
Ding X, Chaiteerakij R, Moser C, Shaleh H, Boakye J, Chen G, et al. Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells. Oncotarget. 2016;7:20080-92 pubmed 出版商
Wittenberg A, Azar S, Klochendler A, Stolovich Rain M, Avraham S, Birnbaum L, et al. Phosphorylated Ribosomal Protein S6 Is Required for Akt-Driven Hyperplasia and Malignant Transformation, but Not for Hypertrophy, Aneuploidy and Hyperfunction of Pancreatic β-Cells. PLoS ONE. 2016;11:e0149995 pubmed 出版商
Dong W, Xiao S, Cheng M, Ye X, Zheng G. Minocycline induces protective autophagy in vascular endothelial cells exposed to an in vitro model of ischemia/reperfusion-induced injury. Biomed Rep. 2016;4:173-177 pubmed
Cullen J, Abdul Murad N, Yeo A, McKenzie M, Ward M, Chong K, et al. AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation. PLoS ONE. 2016;11:e0148213 pubmed 出版商
Su H, Waldron R, Gong R, Ramanujan V, Pandol S, Lugea A. The Unfolded Protein Response Plays a Predominant Homeostatic Role in Response to Mitochondrial Stress in Pancreatic Stellate Cells. PLoS ONE. 2016;11:e0148999 pubmed 出版商
SKU号 :
产品名称 :
规格 :
Price-(USD) :
物种x :
H, M, R, (Mk, B, Pg)
应用 :
产品种类 :
运输温度 :
储存温度 :
产品类型 :
分子量 :
14, 16
宿主 :
靶标 :
最初蛋白 :
别名 :
Autophagy-related protein LC3 B,Autophagy-related ubiquitin-like modifier LC3 B,LC3B,MAP1 light chain 3-like protein 2,MAP1A/1BLC3,MAP1A/MAP1B LC3 B,MAP1A/MAP1B light chain 3 B,MAP1ALC3,MAP1LC3B,MLP3B,Microtubule-associated protein 1 light chain 3 beta,Microtubule-associated proteins 1A/1B light chain 3B,microtubule-associated proteins 1A/1B light chain 3
公司总部: 美国