产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
磷脂酰肌醇(-3)激酶p110β(C33D4)兔单克隆抗体
目录 :
3011
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
C33D4
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫沉淀, 免疫印迹基因敲除验证
文章摘录数: 18
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1000; 图 1a
Araiz C, Yan A, Bettedi L, Samuelson I, Virtue S, McGavigan A, et al. Enhanced β-adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110α inactivation in adipose tissue. Nat Commun. 2019;10:1546 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Liu S, Gao G, Yan D, Chen X, Yao X, Guo S, et al. Effects of miR-145-5p through NRAS on the cell proliferation, apoptosis, migration, and invasion in melanoma by inhibiting MAPK and PI3K/AKT pathways. Cancer Med. 2017;6:819-833 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6c
Yang J, Savvatis K, Kang J, Fan P, Zhong H, Schwartz K, et al. Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment. Nat Commun. 2016;7:13710 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 1
Cizmecioglu O, Ni J, Xie S, Zhao J, Roberts T. Rac1-mediated membrane raft localization of PI3K/p110? is required for its activation by GPCRs or PTEN loss. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 图 s1
Yuzugullu H, Von T, Thorpe L, Walker S, Roberts T, Frank D, et al. NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K-AKT and JAK-STAT3 pathways. Cell Discov. 2016;2:16030 pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Monica V, Lo Iacono M, Bracco E, Busso S, di Blasio L, Primo L, et al. Dasatinib modulates sensitivity to pemetrexed in malignant pleural mesothelioma cell lines. Oncotarget. 2016;7:76577-76589 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Lynch J, McEwen R, Crafter C, McDermott U, Garnett M, Barry S, et al. Identification of differential PI3K pathway target dependencies in T-cell acute lymphoblastic leukemia through a large cancer cell panel screen. Oncotarget. 2016;7:22128-39 pubmed 出版商
  • 免疫印迹; 人类
Perez García V, Redondo Muñoz J, Kumar A, Carrera A. Cell activation-induced phosphoinositide 3-kinase alpha/beta dimerization regulates PTEN activity. Mol Cell Biol. 2014;34:3359-73 pubmed 出版商
Takeda A, Maher T, Zhang Y, Lanahan S, Bucklin M, Compton S, et al. Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology. Nat Commun. 2019;10:4364 pubmed 出版商
Visuttijai K, Pettersson J, Mehrbani Azar Y, van den Bout I, Orndal C, Marcickiewicz J, et al. Lowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT. PLoS ONE. 2016;11:e0164063 pubmed 出版商
Stamatkin C, Ratermann K, Overley C, Black E. Inhibition of class IA PI3K enzymes in non-small cell lung cancer cells uncovers functional compensation among isoforms. Cancer Biol Ther. 2015;16:1341-52 pubmed 出版商
Thapa N, Choi S, Tan X, Wise T, Anderson R. Phosphatidylinositol Phosphate 5-Kinase Iγ and Phosphoinositide 3-Kinase/Akt Signaling Couple to Promote Oncogenic Growth. J Biol Chem. 2015;290:18843-54 pubmed 出版商
Elfineh L, Classon C, Asplund A, Pettersson U, Kamali Moghaddam M, Lind S. Tyrosine phosphorylation profiling via in situ proximity ligation assay. BMC Cancer. 2014;14:435 pubmed 出版商
Cui W, Cai Y, Wang W, Liu Z, Wei P, Bi R, et al. Frequent copy number variations of PI3K/AKT pathway and aberrant protein expressions of PI3K subunits are associated with inferior survival in diffuse large B cell lymphoma. J Transl Med. 2014;12:10 pubmed 出版商
Sacco J, Yau T, Darling S, Patel V, Liu H, Urbé S, et al. The deubiquitylase Ataxin-3 restricts PTEN transcription in lung cancer cells. Oncogene. 2014;33:4265-72 pubmed 出版商
Cumberbatch M, Tang X, Beran G, Eckersley S, Wang X, Ellston R, et al. Identification of a subset of human non-small cell lung cancer patients with high PI3K? and low PTEN expression, more prevalent in squamous cell carcinoma. Clin Cancer Res. 2014;20:595-603 pubmed 出版商
Mouchemore K, Sampaio N, Murrey M, Stanley E, Lannutti B, Pixley F. Specific inhibition of PI3K p110? inhibits CSF-1-induced macrophage spreading and invasive capacity. FEBS J. 2013;280:5228-36 pubmed 出版商
Berends L, Fernandez Twinn D, Martin Gronert M, Cripps R, Ozanne S. Catch-up growth following intra-uterine growth-restriction programmes an insulin-resistant phenotype in adipose tissue. Int J Obes (Lond). 2013;37:1051-7 pubmed 出版商
产品信息
SKU号 :
3011S
产品名称 :
磷脂酰肌醇(-3)激酶p110β(C33D4)兔单克隆抗体
规格 :
100微升
Price-(USD) :
235美元
物种x :
H
应用 :
免疫沉淀
产品种类 :
PI3K / Akt Signaling
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
110
宿主 :
靶标 :
PI3K p110乙
最初蛋白 :
PIK3CB
别名 :
DKFZp779K1237,MGC133043,P110BETA,PI3-kinase p110 subunit beta,PI3-kinase subunit beta,PI3K,PI3K-beta,PI3KBETA,PIK3C1,PIK3CB,PK3CB,Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta,Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform,PtdIns-3-kinase p110,PtdIns-3-kinase subunit beta,PtdIns-3-kinase subunit p110-beta,catalytic phosphatidylinositol 3-kinase beta,phosphoinositide-3-kinase, catalytic, beta polypeptide
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。