产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
磷酸化NF p65(Ser536)(93H1)兔单克隆抗体
目录 :
3033
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
93H1
反应物种 :
人类, 小鼠, 大鼠, , , pigs
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, reverse phase protein lysate microarray, 其他, 免疫印迹基因敲除验证
文章摘录数: 440
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 5i
Ma S, Xu H, Huang W, Gao Y, Zhou H, Li X, et al. Chrysophanol Relieves Cisplatin-Induced Nephrotoxicity via Concomitant Inhibition of Oxidative Stress, Apoptosis, and Inflammation. Front Physiol. 2021;12:706359 pubmed 出版商
  • 免疫印迹; 人类; 图 4b
Zheng J, Yao L, Zhou Y, Gu X, Wang C, Bao K, et al. A novel function of NLRP3 independent of inflammasome as a key transcription factor of IL-33 in epithelial cells of atopic dermatitis. Cell Death Dis. 2021;12:871 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4d, 4g
Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, et al. Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer. Nat Commun. 2021;12:5196 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 7a
  • 免疫印迹; 小鼠; 1:1000; 图 6a
Ho T, Yeh S, Chen S, Tsao Y. Integrin αv and Vitronectin Prime Macrophage-Related Inflammation and Contribute the Development of Dry Eye Disease. Int J Mol Sci. 2021;22: pubmed 出版商
  • 免疫印迹; 人类; 图 s4b
Du Y, Zhang M, Liu X, Li Z, Hu M, Tian Y, et al. CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65. EMBO Rep. 2021;22:e52576 pubmed 出版商
  • 免疫印迹; 人类; 图 1e
  • 免疫印迹; 小鼠; 图 3c
Xu X, Lei Y, Chen L, Zhou H, Liu H, Jiang J, et al. Phosphorylation of NF-κBp65 drives inflammation-mediated hepatocellular carcinogenesis and is a novel therapeutic target. J Exp Clin Cancer Res. 2021;40:253 pubmed 出版商
  • 流式细胞仪; 小鼠
Hutton C, Heider F, Blanco Gómez A, Banyard A, Kononov A, Zhang X, et al. Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity. Cancer Cell. 2021;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 5c
Honda S, Ikeda K, Urata R, Yamazaki E, Emoto N, Matoba S. Cellular senescence promotes endothelial activation through epigenetic alteration, and consequently accelerates atherosclerosis. Sci Rep. 2021;11:14608 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6d
Yang W, Lu X, Zhang T, Han W, Li J, He W, et al. TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling. Bone Res. 2021;9:33 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7b
Lu J, Wang W, Li P, Wang X, Gao C, Zhang B, et al. MiR-146a regulates regulatory T cells to suppress heart transplant rejection in mice. Cell Death Discov. 2021;7:165 pubmed 出版商
  • 免疫印迹; 人类; 图 s3-1n
Jeong D, Kim H, Kim H, Kang M, Jung H, Oh Y, et al. Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2. elife. 2021;10: pubmed 出版商
  • 免疫印迹; 大鼠; 图 3c
Wu Y, Zhang J, Li C, Hu H, Qin B, Wang T, et al. The Activation of ROS/NF-κB/MMP-9 Pathway Promotes Calcium-Induced Kidney Crystal Deposition. Oxid Med Cell Longev. 2021;2021:8836355 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 11c
Lee B, Hong S, Kim M, Kim E, Park H, Jung H, et al. Lycii radicis cortex inhibits glucocorticoid‑induced bone loss by downregulating Runx2 and BMP‑2 expression. Int J Mol Med. 2021;48: pubmed 出版商
  • 免疫印迹; 小鼠; 图 2g
Shen Y, Tang K, Chen D, Hong M, Sun F, Wang S, et al. Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation. Cell Rep. 2021;35:109272 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4c
Frottin F, Pérez Berlanga M, Hartl F, Hipp M. Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model. elife. 2021;10: pubmed 出版商
  • 免疫印迹; 人类; 图 7g
Zhang X, Song L, Li L, Zhu B, Huo L, Hu Z, et al. Phosphatidylserine externalized on the colonic capillaries as a novel pharmacological target for IBD therapy. Signal Transduct Target Ther. 2021;6:235 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3e
Xu X, Huang X, Zhang L, Huang X, Qin Z, Hua F. Adiponectin protects obesity-related glomerulopathy by inhibiting ROS/NF-κB/NLRP3 inflammation pathway. BMC Nephrol. 2021;22:218 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 1e
  • 免疫印迹; 人类; 图 2a
Zhang Z, Zhang L, Zhang Q, Liu B, Li F, Xin Y, et al. HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1-/- Mice. Oxid Med Cell Longev. 2021;2021:6620873 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4b
Jiang D, Zhang J, Lin S, Wang Y, Chen Y, Fan J. Prolyl Endopeptidase Gene Disruption Improves Gut Dysbiosis and Non-alcoholic Fatty Liver Disease in Mice Induced by a High-Fat Diet. Front Cell Dev Biol. 2021;9:628143 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1g
Parodi B, Sanna A, Cedola A, Uccelli A, Kerlero de Rosbo N. Hydroxycarboxylic Acid Receptor 2, a Pleiotropically Linked Receptor for the Multiple Sclerosis Drug, Monomethyl Fumarate. Possible Implications for the Inflammatory Response. Front Immunol. 2021;12:655212 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1d
Atcha H, Jairaman A, Holt J, Meli V, Nagalla R, Veerasubramanian P, et al. Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing. Nat Commun. 2021;12:3256 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6a
  • 免疫印迹; 人类; 图 1a, 4g, 7f
Chen S, Liu H, Li Z, Tang J, Huang B, Zhi F, et al. Epithelial PBLD attenuates intestinal inflammatory response and improves intestinal barrier function by inhibiting NF-κB signaling. Cell Death Dis. 2021;12:563 pubmed 出版商
  • 免疫印迹; 人类; 图 7h
Ma X, Zhao T, Yan H, Guo K, Liu Z, Wei L, et al. Fatostatin reverses progesterone resistance by inhibiting the SREBP1-NF-κB pathway in endometrial carcinoma. Cell Death Dis. 2021;12:544 pubmed 出版商
  • 免疫印迹; 人类; 图 3c
Leon K, Buj R, Lesko E, Dahl E, Chen C, Tangudu N, et al. DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A. J Cell Biol. 2021;220: pubmed 出版商
  • 免疫组化; 小鼠; 1:20; 图 8g
Grol M, Haelterman N, Lim J, Munivez E, Archer M, Hudson D, et al. Tendon and motor phenotypes in the Crtap-/- mouse model of recessive osteogenesis imperfecta. elife. 2021;10: pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Lagosz Cwik K, Wielento A, Lipska W, Kantorowicz M, Darczuk D, Kaczmarzyk T, et al. hTERT-immortalized gingival fibroblasts respond to cytokines but fail to mimic primary cell responses to Porphyromonas gingivalis. Sci Rep. 2021;11:10770 pubmed 出版商
  • 免疫印迹; pigs ; 图 3h
Zong X, Xiao X, Shen B, Jiang Q, Wang H, Lu Z, et al. The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response. Nucleic Acids Res. 2021;49:5537-5552 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5h
Zhang G, Li R, Li W, Yang S, Sun Q, Yin H, et al. Toll-like receptor 3 ablation prevented high-fat diet-induced obesity and metabolic disorder. J Nutr Biochem. 2021;95:108761 pubmed 出版商
  • 免疫印迹; 小鼠; 图 ev2c
Pei G, Zyla J, He L, Moura Alves P, Steinle H, Saikali P, et al. Cellular stress promotes NOD1/2-dependent inflammation via the endogenous metabolite sphingosine-1-phosphate. EMBO J. 2021;40:e106272 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5e
Lu H, Hsu H, Li C, Li S, Lin S, Shih C, et al. Hydrogen Sulfide Attenuates Aortic Remodeling in Aortic Dissection Associating with Moderated Inflammation and Oxidative Stress through a NO-Dependent Pathway. Antioxidants (Basel). 2021;10: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7p
Mu W, Qian S, Song Y, Yang L, Song S, Yang Q, et al. BMP4-mediated browning of perivascular adipose tissue governs an anti-inflammatory program and prevents atherosclerosis. Redox Biol. 2021;43:101979 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 5a
Huo Y, Selenica P, Mahdi A, Pareja F, Kyker Snowman K, Chen Y, et al. Genetic interactions among Brca1, Brca2, Palb2, and Trp53 in mammary tumor development. NPJ Breast Cancer. 2021;7:45 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3a
Qin W, Brands X, Van T Veer C, F de Vos A, Sirard J, J T H Roelofs J, et al. Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection. PLoS Pathog. 2021;17:e1009491 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6g
Yin S, Li L, Tao Y, Yu J, Wei S, Liu M, et al. The Inhibitory Effect of Artesunate on Excessive Endoplasmic Reticulum Stress Alleviates Experimental Colitis in Mice. Front Pharmacol. 2021;12:629798 pubmed 出版商
  • 免疫印迹; 小鼠
Liu X, Jiang J, Liao Y, Tang I, Zheng E, Qiu W, et al. Combination Chemo-Immunotherapy for Pancreatic Cancer Using the Immunogenic Effects of an Irinotecan Silicasome Nanocarrier Plus Anti-PD-1. Adv Sci (Weinh). 2021;8:2002147 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5b
Zhang Y, Liu J, Wang X, Zhang J, Xie C. Extracellular vesicle-encapsulated microRNA-23a from dorsal root ganglia neurons binds to A20 and promotes inflammatory macrophage polarization following peripheral nerve injury. Aging (Albany NY). 2021;13:6752-6764 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 8a
Huang Y, Xiao X, Xiao H, Hu Z, Tan F. CUEDC2 ablation enhances the efficacy of mesenchymal stem cells in ameliorating cerebral ischemia/reperfusion insult. Aging (Albany NY). 2021;13:4335-4356 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3i
Wang Y, Luo M, Chen Y, Wang Y, Zhang B, Ren Z, et al. ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth. Cancer Res. 2021;81:174-186 pubmed 出版商
  • 免疫印迹; pigs ; 图 4a
Tian M, Chen J, Wu Z, Song H, Yang F, Cui C, et al. Fat Encapsulation Reduces Diarrhea in Piglets Partially by Repairing the Intestinal Barrier and Improving Fatty Acid Transport. Animals (Basel). 2020;11: pubmed 出版商
  • 免疫印迹; 小鼠; 图 4f
Zhang D, Liu C, Li H, Jiao J. Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic-Like Behaviors. Adv Sci (Weinh). 2020;7:2002117 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Nakayama A, Albarrán Juárez J, Liang G, Roquid K, Iring A, Tonack S, et al. Disturbed flow-induced Gs-mediated signaling protects against endothelial inflammation and atherosclerosis. JCI Insight. 2020;5: pubmed 出版商
  • 免疫印迹; 小鼠; 图 5c
Hu Q, Lu Y, Hu F, He S, Xu X, Niu Y, et al. Resistant dextrin reduces obesity and attenuates adipose tissue inflammation in high-fat diet-fed mice. Int J Med Sci. 2020;17:2611-2621 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 6c
Wang T, Gao Y, Yue R, Wang X, Shi Y, Xu J, et al. Ginsenoside Rg1 Alleviates Podocyte Injury Induced by Hyperlipidemia via Targeting the mTOR/NF-κB/NLRP3 Axis. Evid Based Complement Alternat Med. 2020;2020:2735714 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 3a
  • 免疫印迹; 人类; 1:1000; 图 1a
Zou X, Zhang D, Song Y, Liu S, Long Q, Yao L, et al. HRG switches TNFR1-mediated cell survival to apoptosis in Hepatocellular Carcinoma. Theranostics. 2020;10:10434-10447 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3b
Sun Z, Ji N, Ma Q, Zhu R, Chen Z, Wang Z, et al. Epithelial-Mesenchymal Transition in Asthma Airway Remodeling Is Regulated by the IL-33/CD146 Axis. Front Immunol. 2020;11:1598 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s6c
Han C, Kang I, Harten I, Gebe J, Chan C, Omer M, et al. Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity. Cell Rep. 2020;31:107818 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2c
Hastings J, González Rajal A, Latham S, Han J, McCloy R, O Donnell Y, et al. Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s10a
Lechertier T, Reynolds L, Kim H, Pedrosa A, Gómez Escudero J, Muñoz Félix J, et al. Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth. Nat Commun. 2020;11:2810 pubmed 出版商
  • 免疫印迹; 人类; 图 5g
Zhao Z, Xiang S, Qi J, Wei Y, Zhang M, Yao J, et al. Correction of the tumor suppressor Salvador homolog-1 deficiency in tumors by lycorine as a new strategy in lung cancer therapy. Cell Death Dis. 2020;11:387 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Du T, Yan Z, Zhu S, Chen G, Wang L, Ye Z, et al. QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism. Cell Death Dis. 2020;11:330 pubmed 出版商
  • 流式细胞仪; 人类; 1:100; 图 2a
Wong S, Lenzini S, Cooper M, Mooney D, Shin J. Soft extracellular matrix enhances inflammatory activation of mesenchymal stromal cells to induce monocyte production and trafficking. Sci Adv. 2020;6:eaaw0158 pubmed 出版商
  • 流式细胞仪; 人类; 图 3a
Einhaus J, Pecher A, Asteriti E, Schmid H, Secker K, Duerr Stoerzer S, et al. Inhibition of effector B cells by ibrutinib in systemic sclerosis. Arthritis Res Ther. 2020;22:66 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1g, 1h, 2e
  • 免疫印迹; 小鼠; 1:1000; 图 2c
Szymura S, Bernal G, Wu L, Zhang Z, Crawley C, Voce D, et al. DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-κB and sensitize to alkylating chemotherapy. BMC Biol. 2020;18:32 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4b, s12b
von Roemeling C, Wang Y, Qie Y, Yuan H, Zhao H, Liu X, et al. Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity. Nat Commun. 2020;11:1508 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6c
Farabaugh K, Krokowski D, Guan B, Gao Z, Gao X, Wu J, et al. PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 5c
Yan S, Ding H, Peng J, Wang X, Pang C, Wei J, et al. Down-regulation of protease-activated receptor 2 ameliorated osteoarthritis in rats through regulation of MAPK/NF-κB signaling pathway in vivo and in vitro. Biosci Rep. 2020;40: pubmed 出版商
  • 免疫印迹; 小鼠; 图 4g
Fu Y, Ding Y, Wang Q, Zhu F, Tan Y, Lu X, et al. Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2. Sci Adv. 2020;6:eaay9269 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 8a
  • 免疫组化-石蜡切片; 大鼠; 1:200; 图 8c
  • 免疫细胞化学; 大鼠; 1:200; 图 s1c
  • 免疫印迹; 大鼠; 1:1000; 图 s1a
Chen F, Jiang G, Liu H, Li Z, Pei Y, Wang H, et al. Melatonin alleviates intervertebral disc degeneration by disrupting the IL-1β/NF-κB-NLRP3 inflammasome positive feedback loop. Bone Res. 2020;8:10 pubmed 出版商
  • 免疫印迹; 人类; 图 5e
Wang S, Qi Y, Gao X, Qiu W, Liu Q, Guo X, et al. Hypoxia-induced lncRNA PDIA3P1 promotes mesenchymal transition via sponging of miR-124-3p in glioma. Cell Death Dis. 2020;11:168 pubmed 出版商
  • 免疫组化; 大鼠; 1:1200; 图 10
Merlo S, Luaces J, Spampinato S, Toro Urrego N, Caruso G, D Amico F, et al. SIRT1 Mediates Melatonin's Effects on Microglial Activation in Hypoxia: In Vitro and In Vivo Evidence. Biomolecules. 2020;10: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5e
Wan G, An Y, Tao J, Wang Y, Zhou Q, Yang R, et al. MicroRNA-129-5p alleviates spinal cord injury in mice via suppressing the apoptosis and inflammatory response through HMGB1/TLR4/NF-κB pathway. Biosci Rep. 2020;40: pubmed 出版商
  • 免疫印迹; 小鼠; 图 3f
Guo X, Kolpakov M, Hooshdaran B, Schappell W, Wang T, Eguchi S, et al. Cardiac Expression of Factor X Mediates Cardiac Hypertrophy and Fibrosis in Pressure Overload. JACC Basic Transl Sci. 2020;5:69-83 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4b
  • 免疫印迹; 人类; 图 6c
Xiang S, Chen K, Xu L, Wang T, Guo C. Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway. Drug Des Devel Ther. 2020;14:129-143 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6l
Pakarinen E, Danilova T, Voikar V, Chmielarz P, Piepponen P, Airavaara M, et al. MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System. Eneuro. 2020;7: pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Lin L, Li Y, Liu M, Li Q, Liu Q, Li R. The Interleukin-33/ST2 axis promotes glioma mesenchymal transition, stemness and TMZ resistance via JNK activation. Aging (Albany NY). 2020;12:1685-1703 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s4
Meng X, Zhao Y, Han B, Zha C, Zhang Y, Li Z, et al. Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways. Nat Commun. 2020;11:594 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s4a
Cheung E, DeNicola G, Nixon C, Blyth K, Labuschagne C, Tuveson D, et al. Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer. Cancer Cell. 2020;37:168-182.e4 pubmed 出版商
  • 免疫印迹; 人类; 图 10a
  • 免疫印迹; 大鼠; 图 7a
Zhang Y, Mao X, Chen W, Guo X, Yu L, Jiang F, et al. A Discovery of Clinically Approved Formula FBRP for Repositioning to Treat HCC by Inhibiting PI3K/AKT/NF-κB Activation. Mol Ther Nucleic Acids. 2020;19:890-904 pubmed 出版商
  • 免疫印迹; 人类; 图 7g
Nixon C, Mavigner M, Sampey G, Brooks A, Spagnuolo R, Irlbeck D, et al. Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo. Nature. 2020;578:160-165 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Lohard S, Bourgeois N, Maillet L, Gautier F, Fétiveau A, Lasla H, et al. STING-dependent paracriny shapes apoptotic priming of breast tumors in response to anti-mitotic treatment. Nat Commun. 2020;11:259 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2b
Li Y, Xu S, Xu Q, Chen Y. Clostridium difficile toxin B induces colonic inflammation through the TRIM46/DUSP1/MAPKs and NF-κB signalling pathway. Artif Cells Nanomed Biotechnol. 2020;48:452-462 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Cai H, Yan L, Liu N, Xu M, Cai H. IFI16 promotes cervical cancer progression by upregulating PD-L1 in immunomicroenvironment through STING-TBK1-NF-kB pathway. Biomed Pharmacother. 2020;123:109790 pubmed 出版商
  • 免疫印迹; 人类; 图 4g
Wang H, Chen Z, Wang S, Gao X, Qian M, Qiu W, et al. TGFβ1-induced beta-site APP-cleaving enzyme 2 upregulation promotes tumorigenesis through the NF-κB signalling pathway in human gliomas. Mol Oncol. 2020;14:407-425 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Jobin P, Solis N, Machado Y, Bell P, Rai S, Kwon N, et al. Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage. J Biol Chem. 2020;295:2186-2202 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1e, 2c
Li Z, Wang H, Zeng Q, Yan J, Hu Y, Li H, et al. p65/miR-23a/CCL22 axis regulated regulatory T cells recruitment in hepatitis B virus positive hepatocellular carcinoma. Cancer Med. 2020;9:711-723 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Zhang R, Liu Y, Chen Y, Li Q, Marshall C, Wu T, et al. Aquaporin 4 deletion exacerbates brain impairments in a mouse model of chronic sleep disruption. CNS Neurosci Ther. 2020;26:228-239 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Zhang Q, Xiang L, Zaman M, Dong W, He G, Deng G. Predominant Role of Immunoglobulin G in the Pathogenesis of Splenomegaly in Murine Lupus. Front Immunol. 2019;10:3020 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Jia Z, Huang Y, Ji X, Sun J, Fu G. Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells. BMC Cardiovasc Disord. 2019;19:318 pubmed 出版商
  • 免疫印迹; 大鼠; 图 6i
Huang X, Ni B, Xi Y, Chu X, Zhang R, You H. Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis. Aging (Albany NY). 2019;11:12532-12545 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Zoi I, Karamouzis M, Xingi E, Sarantis P, Thomaidou D, Lembessis P, et al. Combining RANK/RANKL and ERBB-2 targeting as a novel strategy in ERBB-2-positive breast carcinomas. Breast Cancer Res. 2019;21:132 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6a
  • 免疫细胞化学; 小鼠; 1:100; 图 6e
  • 免疫印迹; 小鼠; 图 2a, 2e
Thirugnanam K, Cossette S, Lu Q, Chowdhury S, Harmann L, Gupta A, et al. Cardiomyocyte-Specific Snrk Prevents Inflammation in the Heart. J Am Heart Assoc. 2019;8:e012792 pubmed 出版商
  • 免疫印迹; 人类; 图 ev4b
Weiterer S, Meier Soelch J, Georgomanolis T, Mizi A, Beyerlein A, Weiser H, et al. Distinct IL-1α-responsive enhancers promote acute and coordinated changes in chromatin topology in a hierarchical manner. EMBO J. 2019;:e101533 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:100; 图 7c
  • 免疫印迹; 大鼠; 1:400; 图 7a
Xia Y, Xue M, Wang Y, Huang Z, Huang C. Electroacupuncture Alleviates Spared Nerve Injury-Induced Neuropathic Pain And Modulates HMGB1/NF-κB Signaling Pathway In The Spinal Cord. J Pain Res. 2019;12:2851-2863 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1n, 3g
Lu Y, Zheng Y, Coyaud E, Zhang C, Selvabaskaran A, Yu Y, et al. Palmitoylation of NOD1 and NOD2 is required for bacterial sensing. Science. 2019;366:460-467 pubmed 出版商
  • 免疫印迹; 小鼠; 图 e6j
Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Nature. 2019;574:553-558 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1f
Miyazaki T, Zhao Z, Ichihara Y, Yoshino D, Imamura T, Sawada K, et al. Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity. Sci Adv. 2019;5:eaau7802 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2b
Wang P, Qi X, Xu G, Liu J, Guo J, Li X, et al. CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells. Aging (Albany NY). 2019;11:7402-7415 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Zhu B, Ren C, Du K, Zhu H, Ai Y, Kang F, et al. Olean-28,13b-olide 2 plays a role in cisplatin-mediated apoptosis and reverses cisplatin resistance in human lung cancer through multiple signaling pathways. Biochem Pharmacol. 2019;170:113642 pubmed 出版商
  • 免疫印迹; 人类; 图 2d
Managò A, Audrito V, Mazzola F, Sorci L, Gaudino F, Gizzi K, et al. Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation. Nat Commun. 2019;10:4116 pubmed 出版商
  • 免疫印迹; 小鼠; 图 10b
Zhou C, Sun X, Hu Y, Song J, Dong S, Kong D, et al. Genomic deletion of TLR2 induces aggravated white matter damage and deteriorated neurobehavioral functions in mouse models of Alzheimer's disease. Aging (Albany NY). 2019;11:7257-7273 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6a
Ng A, Li Z, Jones M, Yang S, Li C, Fu C, et al. Regulator of G protein signaling 12 enhances osteoclastogenesis by suppressing Nrf2-dependent antioxidant proteins to promote the generation of reactive oxygen species. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 4a
Shang S, Ji X, Zhang L, Chen J, Li C, Shi R, et al. Macrophage ABHD5 Suppresses NFκB-Dependent Matrix Metalloproteinase Expression and Cancer Metastasis. Cancer Res. 2019;79:5513-5526 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4g
Gal H, Lysenko M, Stroganov S, Vadai E, Youssef S, Tzadikevitch Geffen K, et al. Molecular pathways of senescence regulate placental structure and function. EMBO J. 2019;38:e100849 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Jobin P, Solis N, Machado Y, Bell P, Kwon N, Kim S, et al. Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase. J Biol Chem. 2019;294:12866-12879 pubmed 出版商
  • 免疫印迹; 人类; 图 6a, 6b
Xu Y, Zhang Q, Zhou J, Li Z, Guo J, Wang W, et al. Down-regulation of SOX18 inhibits laryngeal carcinoma cell proliferation, migration, and invasion through JAK2/STAT3 signaling. Biosci Rep. 2019;: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 3a
Rosenbaum M, Gewies A, Pechloff K, Heuser C, Engleitner T, Gehring T, et al. Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells. Nat Commun. 2019;10:2352 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5g, 5h
  • 免疫印迹; 人类; 图 5a, 5b
Kong L, Wu Z, Zhao Y, Lu X, Shi H, Liu S, et al. Qigesan reduces the motility of esophageal cancer cells via inhibiting Gas6/Axl and NF-κB expression. Biosci Rep. 2019;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 3d
  • 免疫印迹; pigs ; 图 1h
Liu Y, Li R, Chen X, Zhi Y, Deng R, Zhou E, et al. Nonmuscle Myosin Heavy Chain IIA Recognizes Sialic Acids on Sialylated RNA Viruses To Suppress Proinflammatory Responses via the DAP12-Syk Pathway. MBio. 2019;10: pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Zhang H, Wang J, Wang Y, Gao C, Gu Y, Huang J, et al. Salvianolic Acid A Protects the Kidney against Oxidative Stress by Activating the Akt/GSK-3β/Nrf2 Signaling Pathway and Inhibiting the NF-κB Signaling Pathway in 5/6 Nephrectomized Rats. Oxid Med Cell Longev. 2019;2019:2853534 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 s8a
  • 免疫印迹; 小鼠; 1:1000; 图 6c
Ben J, Jiang B, Wang D, Liu Q, Zhang Y, Qi Y, et al. Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation. Nat Commun. 2019;10:1801 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 4d
Udden S, Kwak Y, Godfrey V, Khan M, Khan S, Loof N, et al. NLRP12 suppresses hepatocellular carcinoma via downregulation of cJun N-terminal kinase activation in the hepatocyte. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1f
Walens A, DiMarco A, Lupo R, Kroger B, Damrauer J, Alvarez J. CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5h
Liu X, Chen H, Hou Y, Ma X, Ye M, Huang R, et al. Adaptive EGF expression sensitizes pancreatic cancer cells to ionizing radiation through activation of the cyclin D1/P53/PARP pathway. Int J Oncol. 2019;54:1466-1480 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2d
Wu J, Ma S, Sandhoff R, Ming Y, Hotz Wagenblatt A, Timmerman V, et al. Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness. Immunity. 2019;50:1218-1231.e5 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2b
  • 免疫印迹基因敲除验证; 人类; 图 e5b
  • 免疫印迹; 人类; 图 e6a
Liu Z, Mar K, Hanners N, Perelman S, Kanchwala M, Xing C, et al. A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB. Nature. 2019;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 1i
Tan Y, Kagan J. Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility. Cell. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 图 6f
  • 免疫印迹; 小鼠; 图 6b
Mentrup T, Theodorou K, Cabrera Cabrera F, Helbig A, Happ K, Gijbels M, et al. Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis. J Exp Med. 2019;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
Losier T, Akuma M, McKee Muir O, LeBlond N, Suk Y, Alsaadi R, et al. AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles. Cell Rep. 2019;26:2150-2165.e5 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3a, 3c, s3d
Liu Z, Wu C, Pan Y, Liu H, Wang X, Yang Y, et al. NDR2 promotes the antiviral immune response via facilitating TRIM25-mediated RIG-I activation in macrophages. Sci Adv. 2019;5:eaav0163 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6d
Wu W, Zhang W, Choi M, Zhao J, Gao P, Xue M, et al. Vascular smooth muscle-MAPK14 is required for neointimal hyperplasia by suppressing VSMC differentiation and inducing proliferation and inflammation. Redox Biol. 2019;22:101137 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2c
Huang X, Feng Z, Jiang Y, Li J, Xiang Q, Guo S, et al. VSIG4 mediates transcriptional inhibition of Nlrp3 and Il-1β in macrophages. Sci Adv. 2019;5:eaau7426 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2b
Wheeler M, Jaronen M, Covacu R, Zandee S, Scalisi G, Rothhammer V, et al. Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation. Cell. 2019;176:581-596.e18 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4b
Fan Y, Yang L, Wei Q, Ding Y, Tang Z, Tan P, et al. Toll-like receptor 10 (TLR10) exhibits suppressive effects on inflammation of prostate epithelial cells. Asian J Androl. 2019;21:393-399 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Zhang J, Wang D, Wang L, Wang S, Roden A, Zhao H, et al. Profibrotic effect of IL-17A and elevated IL-17RA in idiopathic pulmonary fibrosis and rheumatoid arthritis-associated lung disease support a direct role for IL-17A/IL-17RA in human fibrotic interstitial lung disease. Am J Physiol Lung Cell Mol Physiol. 2019;316:L487-L497 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4b
Ye P, Liu J, Xu W, Liu D, Ding X, Le S, et al. Dual-Specificity Phosphatase 26 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through Transforming Growth Factor Beta-Activated Kinase 1 Suppression. Hepatology. 2019;69:1946-1964 pubmed 出版商
  • 免疫印迹; 人类; 图 3a, 3b
Lou C, Lu H, Ma Z, Liu C, Zhang Y. Ginkgolide B enhances gemcitabine sensitivity in pancreatic cancer cell lines via inhibiting PAFR/NF-кB pathway. Biomed Pharmacother. 2019;109:563-572 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1f
Biffi G, Oni T, Spielman B, Hao Y, Elyada E, Park Y, et al. IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma. Cancer Discov. 2019;9:282-301 pubmed 出版商
  • 免疫印迹; 人类; 图 7c
Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2019;26:1138-1155 pubmed 出版商
  • 流式细胞仪; 人类; 图 2d
Richardson J, Armbruster N, Günter M, Henes J, Autenrieth S. Staphylococcus aureus PSM Peptides Modulate Human Monocyte-Derived Dendritic Cells to Prime Regulatory T Cells. Front Immunol. 2018;9:2603 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1e
Mouhadeb O, Ben Shlomo S, Cohen K, Farkash I, Gruber S, Maharshak N, et al. Impaired COMMD10-Mediated Regulation of Ly6Chi Monocyte-Driven Inflammation Disrupts Gut Barrier Function. Front Immunol. 2018;9:2623 pubmed 出版商
  • 免疫组化; 小鼠; 图 6d
  • 免疫印迹; 小鼠; 图 3e
Hakuno D, Kimura M, Ito S, Satoh J, Nakashima Y, Horie T, et al. Hepatokine α1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction. Sci Rep. 2018;8:16749 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 8d
Zhu H, Zhang L, Wu Y, Dong B, Guo W, Wang M, et al. T-ALL leukemia stem cell 'stemness' is epigenetically controlled by the master regulator SPI1. elife. 2018;7: pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Luong P, Hedl M, Yan J, Zuo T, Fu T, Jiang X, et al. INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling. elife. 2018;7: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3g, 4c
Zhang X, Zhang M, Wang C. Loss of LRRC25 accelerates pathological cardiac hypertrophy through promoting fibrosis and inflammation regulated by TGF-β1. Biochem Biophys Res Commun. 2018;506:137-144 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6a
Yin J, Wang Y, Chang J, Li B, Zhang J, Liu Y, et al. Apelin inhibited epithelial-mesenchymal transition of podocytes in diabetic mice through downregulating immunoproteasome subunits β5i. Cell Death Dis. 2018;9:1031 pubmed 出版商
  • 免疫印迹; 小鼠; 图 8a
Chen S, Yun F, Yao Y, Cao M, Zhang Y, Wang J, et al. USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein. J Exp Med. 2018;215:2850-2867 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
Chorzalska A, Morgan J, Ahsan N, Treaba D, Olszewski A, Petersen M, et al. Bone marrow-specific loss of ABI1 induces myeloproliferative neoplasm with features resembling human myelofibrosis. Blood. 2018;: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7b
Cao Y, Xu Y, Auchoybur M, Chen W, He S, Qin W, et al. Regulatory role of IKKɑ in myocardial ischemia/reperfusion injury by the determination of M1 versus M2 polarization of macrophages. J Mol Cell Cardiol. 2018;123:1-12 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6c
Kang L, Kwon E, Lee K, Cho C, Lee J, Ryu Y, et al. 3'-Sialyllactose as an inhibitor of p65 phosphorylation ameliorates the progression of experimental rheumatoid arthritis. Br J Pharmacol. 2018;175:4295-4309 pubmed 出版商
  • 免疫印迹; 人类; 图 6d
Lee S, North K, Kim E, Jang E, Obeng E, Lu S, et al. Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations. Cancer Cell. 2018;34:225-241.e8 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s6a
Cuchet Lourenço D, Eletto D, Wu C, Plagnol V, Papapietro O, CURTIS J, et al. Biallelic RIPK1 mutations in humans cause severe immunodeficiency, arthritis, and intestinal inflammation. Science. 2018;361:810-813 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s4a
Liu Z, Qin Q, Wu C, Li H, Shou J, Yang Y, et al. Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop. Nat Commun. 2018;9:2789 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7a
Tan B, Shi X, Zhang J, Qin J, Zhang N, Ren H, et al. Inhibition of Rspo-Lgr4 Facilitates Checkpoint Blockade Therapy by Switching Macrophage Polarization. Cancer Res. 2018;78:4929-4942 pubmed 出版商
  • 免疫印迹; 人类; 图 2b
Dai L, Del Valle L, Miley W, Whitby D, Ochoa A, Flemington E, et al. Transactivation of human endogenous retrovirus K (HERV-K) by KSHV promotes Kaposi's sarcoma development. Oncogene. 2018;37:4534-4545 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5b
Song H, Li X, Liu Y, Lu W, Cui Z, Zhou L, et al. Carnosic acid protects mice from high-fat diet-induced NAFLD by regulating MARCKS. Int J Mol Med. 2018;42:193-207 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6h
Xi J, Huang Q, Wang L, Ma X, Deng Q, Kumar M, et al. miR-21 depletion in macrophages promotes tumoricidal polarization and enhances PD-1 immunotherapy. Oncogene. 2018;37:3151-3165 pubmed 出版商
  • 其他; 人类; 图 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Sun J, Wang Z, Wang X. Suppression of LRRC19 promotes cutaneous wound healing in pressure ulcers in mice. Organogenesis. 2018;14:13-24 pubmed 出版商
  • 免疫印迹; 人类; 图 4j
  • 免疫印迹; 小鼠; 图 5f
Zhang H, Song Y, Yang H, Liu Z, Gao L, Liang X, et al. Tumor cell-intrinsic Tim-3 promotes liver cancer via NF-κB/IL-6/STAT3 axis. Oncogene. 2018;37:2456-2468 pubmed 出版商
  • 免疫印迹; 人类; 图 7c
Bogdan D, Falcone J, Kanjiya M, Park S, Carbonetti G, Studholme K, et al. Fatty acid-binding protein 5 controls microsomal prostaglandin E synthase 1 (mPGES-1) induction during inflammation. J Biol Chem. 2018;293:5295-5306 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5m
Jung Y, Cackowski F, Yumoto K, Decker A, Wang J, Kim J, et al. CXCL12γ Promotes Metastatic Castration-Resistant Prostate Cancer by Inducing Cancer Stem Cell and Neuroendocrine Phenotypes. Cancer Res. 2018;78:2026-2039 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6c
Liu F, Dai M, Xu Q, Zhu X, Zhou Y, Jiang S, et al. SRSF10-mediated IL1RAP alternative splicing regulates cervical cancer oncogenesis via mIL1RAP-NF-κB-CD47 axis. Oncogene. 2018;37:2394-2409 pubmed 出版商
  • 免疫印迹; 人类; 图 5h
Su S, Chen J, Yao H, Liu J, Yu S, Lao L, et al. CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness. Cell. 2018;172:841-856.e16 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 11h
Sui Y, Liu Z, Park S, Thatcher S, Zhu B, Fernandez J, et al. IKKβ is a β-catenin kinase that regulates mesenchymal stem cell differentiation. JCI Insight. 2018;3: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3h
Xu S, Zhou Z, Li H, Liu Z, Pan X, Wang F, et al. BMSCs ameliorate septic coagulopathy by suppressing inflammation in cecal ligation and puncture-induced sepsis. J Cell Sci. 2018;131: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Yang L, Shen L, Gao P, Li G, He Y, Wang M, et al. Effect of AMPK signal pathway on pathogenesis of abdominal aortic aneurysms. Oncotarget. 2017;8:92827-92840 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2c
Padilla J, Carpenter A, Das N, Kandikattu H, López Ongil S, Martinez Lemus L, et al. TRAF3IP2 mediates high glucose-induced endothelin-1 production as well as endothelin-1-induced inflammation in endothelial cells. Am J Physiol Heart Circ Physiol. 2018;314:H52-H64 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Wu G, Mu T, Gao Z, Wang J, Sy M, Li C. Prion protein is required for tumor necrosis factor α (TNFα)-triggered nuclear factor κB (NF-κB) signaling and cytokine production. J Biol Chem. 2017;292:18747-18759 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7b
Yang Y, Yang S, Guo J, Cui Y, Tang B, Li X, et al. Synergistic Toxicity of Polyglutamine-Expanded TATA-Binding Protein in Glia and Neuronal Cells: Therapeutic Implications for Spinocerebellar Ataxia 17. J Neurosci. 2017;37:9101-9115 pubmed 出版商
  • 免疫印迹; 人类; 图 3c
Franz S, Rennert P, Woznik M, Grützke J, Lüdde A, Arriero Pais E, et al. Mumps Virus SH Protein Inhibits NF-κB Activation by Interacting with Tumor Necrosis Factor Receptor 1, Interleukin-1 Receptor 1, and Toll-Like Receptor 3 Complexes. J Virol. 2017;91: pubmed 出版商
  • 免疫印迹; 小鼠; 图 2f
Huh H, Lee E, Shin J, Park B, Lee S. STRAP positively regulates TLR3-triggered signaling pathway. Cell Immunol. 2017;318:55-60 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s13a
Qiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, et al. The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis. Nat Commun. 2017;8:15426 pubmed 出版商
  • 流式细胞仪; 人类; 图 8c
Domae E, Hirai Y, Ikeo T, Goda S, Shimizu Y. Cytokine-mediated activation of human ex vivo-expanded V?9V?2 T cells. Oncotarget. 2017;8:45928-45942 pubmed 出版商
  • 免疫印迹; 人类; 图 4f
van Wijk S, Fricke F, Herhaus L, Gupta J, Hötte K, Pampaloni F, et al. Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-?B and restricts bacterial proliferation. Nat Microbiol. 2017;2:17066 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类; 图 2a, 2c, 2d
Wang X, Wang R, Luo M, Li C, Wang H, Huan C, et al. (DEAD)-box RNA helicase 3 modulates NF-κB signal pathway by controlling the phosphorylation of PP2A-C subunit. Oncotarget. 2017;8:33197-33213 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 7b
Xiong G, Hindi S, Mann A, Gallot Y, Bohnert K, Cavener D, et al. The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration. elife. 2017;6: pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 图 st6
Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 图 6d
  • 免疫印迹; 大鼠; 1:1000; 图 6a
Zeng W, Han Y, Zhu G, Huang L, Deng Y, Wang Q, et al. Hypertonic saline attenuates expression of Notch signaling and proinflammatory mediators in activated microglia in experimentally induced cerebral ischemia and hypoxic BV-2 microglia. BMC Neurosci. 2017;18:32 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 3a
Song Y, Lai L, Chong Z, He J, Zhang Y, Xue Y, et al. E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses. Nat Commun. 2017;8:14654 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s1
Loo L, Bougen Zhukov N, Tan W. Early spatiotemporal-specific changes in intermediate signals are predictive of cytotoxic sensitivity to TNFα and co-treatments. Sci Rep. 2017;7:43541 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:200; 图 3
Zinni M, Zuena A, Marconi V, Petrella C, Fusco I, Giuli C, et al. Maternal exposure to low levels of corticosterone during lactation protects adult rat progeny against TNBS-induced colitis: A study on GR-mediated anti-inflammatory effect and prokineticin system. PLoS ONE. 2017;12:e0173484 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5b
  • 免疫印迹; 人类; 图 5a
Ma C, Lin W, Liu Z, Tang W, Gautam R, Li H, et al. NDR1 protein kinase promotes IL-17- and TNF-α-mediated inflammation by competitively binding TRAF3. EMBO Rep. 2017;18:586-602 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a, 3a
  • 免疫印迹; 人类; 图 2b
Hsia H, Hutti J, Baldwin A. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity. J Biol Chem. 2017;292:5405-5417 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5b
Zhang H, Qi Y, Yuan Y, Cai L, Xu H, Zhang L, et al. Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation. Sci Rep. 2017;7:41887 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7c
Xiong X, Liu Y, Mei Y, Peng J, Wang Z, Kong B, et al. Novel Protective Role of Myeloid Differentiation 1 in Pathological Cardiac Remodelling. Sci Rep. 2017;7:41857 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Zeng Q, Song R, Fullerton D, Ao L, Zhai Y, Li S, et al. Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice. Proc Natl Acad Sci U S A. 2017;114:1631-1636 pubmed 出版商
  • 免疫印迹; 人类; 图 4b
Lin Y, Lin Y, Huang M, Kuo P, Wu C, Lee M, et al. Tumor necrosis factor-alpha inhibitors suppress CCL2 chemokine in monocytes via epigenetic modification. Mol Immunol. 2017;83:82-91 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 图 3a
. Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7a
Schober T, Magg T, Laschinger M, Rohlfs M, Linhares N, Puchalka J, et al. A human immunodeficiency syndrome caused by mutations in CARMIL2. Nat Commun. 2017;8:14209 pubmed 出版商
  • 免疫印迹; 人类; 图 4e
Indrakusuma I, Romacho T, Eckel J. Protease-Activated Receptor 2 Promotes Pro-Atherogenic Effects through Transactivation of the VEGF Receptor 2 in Human Vascular Smooth Muscle Cells. Front Pharmacol. 2016;7:497 pubmed 出版商
  • 免疫印迹; 人类; 图 7g
Cianciola N, Chung S, Manor D, Carlin C. Adenovirus Modulates Toll-Like Receptor 4 Signaling by Reprogramming ORP1L-VAP Protein Contacts for Cholesterol Transport from Endosomes to the Endoplasmic Reticulum. J Virol. 2017;91: pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 5h
Oller J, Méndez Barbero N, Ruiz E, Villahoz S, Renard M, Canelas L, et al. Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome. Nat Med. 2017;23:200-212 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3a
Hichino A, Okamoto M, Taga S, Akizuki R, Endo S, Matsunaga T, et al. Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells. J Biol Chem. 2017;292:2411-2421 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1a
Hammers D, Sleeper M, Forbes S, Coker C, Jirousek M, Zimmer M, et al. Disease-modifying effects of orally bioavailable NF-κB inhibitors in dystrophin-deficient muscle. JCI Insight. 2016;1:e90341 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6d
Chao M, Guo J, Cheng W, Zhu X, She Z, Huang Z, et al. Loss of Caspase-Activated DNase Protects Against Atherosclerosis in Apolipoprotein E-Deficient Mice. J Am Heart Assoc. 2016;5: pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 7a
Liu W, Sun Y, He Y, Zhang H, Zheng Y, Yao Y, et al. IL-1? impedes the chondrogenic differentiation of synovial fluid mesenchymal stem cells in the human temporomandibular joint. Int J Mol Med. 2017;39:317-326 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Zhang W, Kang M, Zhang T, Li B, Liao X, Wang R. Triptolide Combined with Radiotherapy for the Treatment of Nasopharyngeal Carcinoma via NF-κB-Related Mechanism. Int J Mol Sci. 2016;17: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5e
Shahriari K, Shen F, Worrede Mahdi A, Liu Q, Gong Y, Garcia F, et al. Cooperation among heterogeneous prostate cancer cells in the bone metastatic niche. Oncogene. 2017;36:2846-2856 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
Huh H, Ra E, Lee T, Kang S, Park A, Lee E, et al. STRAP Acts as a Scaffolding Protein in Controlling the TLR2/4 Signaling Pathway. Sci Rep. 2016;6:38849 pubmed 出版商
  • 免疫印迹; 人类; 图 2d
Tsai C, Lin Y, Huang C, Shih C, Tsai Y, Tsao N, et al. Thrombomodulin regulates monocye differentiation via PKC? and ERK1/2 pathway in vitro and in atherosclerotic artery. Sci Rep. 2016;6:38421 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7b
Schliesser M, Claus R, Hielscher T, Grimm C, Weichenhan D, Blaes J, et al. Prognostic relevance of miRNA-155 methylation in anaplastic glioma. Oncotarget. 2016;7:82028-82045 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Klaska I, Muckersie E, Martin Granados C, Christofi M, Forrester J. Lipopolysaccharide-primed heterotolerant dendritic cells suppress experimental autoimmune uveoretinitis by multiple mechanisms. Immunology. 2017;150:364-377 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Lin T, Cheng C, Su H, Huang N, Chen J, Kang H, et al. Lipopolysaccharide Attenuates Induction of Proallergic Cytokines, Thymic Stromal Lymphopoietin, and Interleukin 33 in Respiratory Epithelial Cells Stimulated with PolyI:C and Human Parechovirus. Front Immunol. 2016;7:440 pubmed
  • 免疫印迹; 小鼠; 图 s3h
Newton K, Wickliffe K, Maltzman A, Dugger D, Strasser A, Pham V, et al. RIPK1 inhibits ZBP1-driven necroptosis during development. Nature. 2016;540:129-133 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Lin J, Kumari S, Kim C, Van T, Wachsmuth L, Polykratis A, et al. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature. 2016;540:124-128 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s5e
Ulland T, Jain N, Hornick E, Elliott E, Clay G, Sadler J, et al. Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment. Nat Commun. 2016;7:13180 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7b
Omiya S, Omori Y, Taneike M, Protti A, Yamaguchi O, Akira S, et al. Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation. Am J Physiol Heart Circ Physiol. 2016;311:H1485-H1497 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50; 图 2i
  • 免疫印迹; 人类; 1:1000; 图 2g
Jiang Y, Zeng Y, Huang X, Qin Y, Luo W, Xiang S, et al. Nur77 attenuates endothelin-1 expression via downregulation of NF-κB and p38 MAPK in A549 cells and in an ARDS rat model. Am J Physiol Lung Cell Mol Physiol. 2016;311:L1023-L1035 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3a
Zhou Z, Tang Y, Jin X, Chen C, Lu Y, Liu L, et al. Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NF?B Pathway Suppression. J Diabetes Res. 2016;2016:4847812 pubmed
  • 免疫印迹; 小鼠; 图 6d
Kennedy T, Swiderski K, Murphy K, Gehrig S, Curl C, Chandramouli C, et al. BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle. Am J Pathol. 2016;186:3246-3260 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 9a
He Y, Yan Y, Zhang H, Lin Y, Chen Y, Yan Y, et al. Methyl salicylate 2-O-?-d-lactoside alleviates the pathological progression of pristane-induced systemic lupus erythematosus-like disease in mice via suppression of inflammatory response and signal transduction. Drug Des Devel Ther. 2016;10:3183-3196 pubmed
  • 免疫印迹; 小鼠; 图 4
Figueroa González G, García Castillo V, Coronel Hernández J, López Urrutia E, León Cabrera S, Arias Romero L, et al. Anti-inflammatory and Antitumor Activity of a Triple Therapy for a Colitis-Related Colorectal Cancer. J Cancer. 2016;7:1632-1644 pubmed
  • 免疫印迹; 人类; 图 4a
Lu W, Shi J, Zhang J, Lv Z, Guo F, Huang H, et al. CXCL12/CXCR4 Axis Regulates Aggrecanase Activation and Cartilage Degradation in a Post-Traumatic Osteoarthritis Rat Model. Int J Mol Sci. 2016;17: pubmed
  • 免疫印迹; 人类; 1:1000; 图 st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Sikora M, Jacobsen B, Levine K, Chen J, Davidson N, Lee A, et al. WNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell lines. Breast Cancer Res. 2016;18:92 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2f
Kaneda M, Messer K, Ralainirina N, Li H, Leem C, Gorjestani S, et al. PI3Kγ is a molecular switch that controls immune suppression. Nature. 2016;539:437-442 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s8d
Hirai Yuki A, Hensley L, McGivern D, Gonzalez Lopez O, Das A, Feng H, et al. MAVS-dependent host species range and pathogenicity of human hepatitis A virus. Science. 2016;353:1541-1545 pubmed
  • 免疫印迹; 小鼠; 1:1000; 图 2a
Bettaieb A, Cremonini E, Kang H, Kang J, Haj F, Oteiza P. Anti-inflammatory actions of (-)-epicatechin in the adipose tissue of obese mice. Int J Biochem Cell Biol. 2016;81:383-392 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
Ando Y, Oku T, Tsuji T. Platelet Supernatant Suppresses LPS-Induced Nitric Oxide Production from Macrophages Accompanied by Inhibition of NF-?B Signaling and Increased Arginase-1 Expression. PLoS ONE. 2016;11:e0162208 pubmed 出版商
  • 免疫印迹; 人类; 表 1
Scott D, Rhee D, Duda D, Kelsall I, Olszewski J, Paulo J, et al. Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation. Cell. 2016;166:1198-1214.e24 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s15
Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun. 2016;7:12547 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
Damgaard R, Walker J, Marco Casanova P, Morgan N, Titheradge H, Elliott P, et al. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. Cell. 2016;166:1215-1230.e20 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 3
Saggu R, Schumacher T, Gerich F, Rakers C, Tai K, Delekate A, et al. Astroglial NF-kB contributes to white matter damage and cognitive impairment in a mouse model of vascular dementia. Acta Neuropathol Commun. 2016;4:76 pubmed 出版商
  • 免疫印迹; 小鼠; 图 9
Pang J, Wu Y, Peng J, Yang P, Kuai L, Qin X, et al. Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of blood-brain barrier integrity. Oncotarget. 2016;7:56030-56044 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2b
Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, et al. IRF3 promotes adipose inflammation and insulin resistance and represses browning. J Clin Invest. 2016;126:2839-54 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Taminiau A, Draime A, Tys J, Lambert B, Vandeputte J, Nguyen N, et al. HOXA1 binds RBCK1/HOIL-1 and TRAF2 and modulates the TNF/NF-?B pathway in a transcription-independent manner. Nucleic Acids Res. 2016;44:7331-49 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Kim H, Choi M, Inn K, Kim B. Inhibition of HIV-1 reactivation by a telomerase-derived peptide in a HSP90-dependent manner. Sci Rep. 2016;6:28896 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 8a
Xiang N, Liu J, Liao Y, Huang Y, Wu Z, Bai Z, et al. Abrogating ClC-3 Inhibits LPS-induced Inflammation via Blocking the TLR4/NF-κB Pathway. Sci Rep. 2016;6:27583 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed 出版商
  • 免疫印迹; 人类; 图 s5
Li Y, Liu C, Su T, Cheng H, Jeng Y, Lin H, et al. Characterization of metastatic tumor antigen 1 and its interaction with hepatitis B virus X protein in NF-κB signaling and tumor progression in a woodchuck hepatocellular carcinoma model. Oncotarget. 2016;7:47173-47185 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Ahmad F, Chung Y, Tang Y, Hockman S, Liu S, Khan Y, et al. Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue. Sci Rep. 2016;6:28056 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Wagner S, Satpathy S, Beli P, Choudhary C. SPATA2 links CYLD to the TNF-? receptor signaling complex and modulates the receptor signaling outcomes. EMBO J. 2016;35:1868-84 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Li Q, Karim A, Ding X, Das B, Dobrowolski C, Gibson R, et al. Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis. Sci Rep. 2016;6:27566 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Duran C, Lee D, Jung J, Ravi S, Pogue C, Toussaint L, et al. NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-?B pathway. Oncogenesis. 2016;5:e231 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2h
Shutinoski B, Alturki N, Rijal D, Bertin J, Gough P, Schlossmacher M, et al. K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo. Cell Death Differ. 2016;23:1628-37 pubmed 出版商
  • 免疫细胞化学; 人类; 1:20; 图 5
Han B, Poppinga W, Zuo H, Zuidhof A, Bos I, Smit M, et al. The novel compound Sul-121 inhibits airway inflammation and hyperresponsiveness in experimental models of chronic obstructive pulmonary disease. Sci Rep. 2016;6:26928 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Yu H. Sphingosine-1-Phosphate Receptor 2 Regulates Proinflammatory Cytokine Production and Osteoclastogenesis. PLoS ONE. 2016;11:e0156303 pubmed 出版商
  • 流式细胞仪; 人类
  • 免疫印迹; 人类; 图 7a
Kwon H, Choi G, Ryu S, Kwon S, Kim S, Booth C, et al. Stepwise phosphorylation of p65 promotes NF-?B activation and NK cell responses during target cell recognition. Nat Commun. 2016;7:11686 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
Song X, Yao Z, Yang J, Zhang Z, Deng Y, Li M, et al. HCV core protein binds to gC1qR to induce A20 expression and inhibit cytokine production through MAPKs and NF-κB signaling pathways. Oncotarget. 2016;7:33796-808 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Wang X, Wan H, Wei X, Zhang Y, Qu P. CLI-095 decreases atherosclerosis by modulating foam cell formation in apolipoprotein E-deficient mice. Mol Med Rep. 2016;14:49-56 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Tortola L, Nitsch R, Bertrand M, Kogler M, Redouane Y, Kozieradzki I, et al. The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate. Cell Rep. 2016;15:1481-1492 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 4
Roth S, Spalinger M, Gottier C, Biedermann L, Zeitz J, Lang S, et al. Bilberry-Derived Anthocyanins Modulate Cytokine Expression in the Intestine of Patients with Ulcerative Colitis. PLoS ONE. 2016;11:e0154817 pubmed 出版商
  • 免疫印迹; 牛; 图 9f
  • 免疫印迹; 人类; 图 9e
Ishizuka S, Askew E, Ishizuka N, Knudson C, Knudson W. 4-Methylumbelliferone Diminishes Catabolically Activated Articular Chondrocytes and Cartilage Explants via a Mechanism Independent of Hyaluronan Inhibition. J Biol Chem. 2016;291:12087-104 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500; 图 6
Tang S, Su H, Zhang Q, Tang H, Wang C, Zhou Q, et al. Sitagliptin inhibits endothelin-1 expression in the aortic endothelium of rats with streptozotocin-induced diabetes by suppressing the nuclear factor-?B/I?B? system through the activation of AMP-activated protein kinase. Int J Mol Med. 2016;37:1558-66 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Wang X, Wang N, Li H, Liu M, Cao F, Yu X, et al. Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine. Int J Mol Sci. 2016;17:577 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1
Uto T, Fukaya T, Takagi H, Arimura K, Nakamura T, Kojima N, et al. Clec4A4 is a regulatory receptor for dendritic cells that impairs inflammation and T-cell immunity. Nat Commun. 2016;7:11273 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Lin A, Wang G, Zhao H, Zhang Y, Han Q, Zhang C, et al. TLR4 signaling promotes a COX-2/PGE2/STAT3 positive feedback loop in hepatocellular carcinoma (HCC) cells. Oncoimmunology. 2016;5:e1074376 pubmed
  • 免疫印迹; 人类; 1:500; 图 8
Canton J, Schlam D, Breuer C, Gutschow M, Glogauer M, Grinstein S. Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages. Nat Commun. 2016;7:11284 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5e
Damle S, Martin R, Cross J, Conrad D. Macrophage migration inhibitory factor deficiency enhances immune response to Nippostrongylus brasiliensis. Mucosal Immunol. 2017;10:205-214 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
  • 免疫印迹; 人类; 图 1
West A, Martin B, Andrews D, Hogg S, Banerjee A, Grigoriadis G, et al. The SMAC mimetic, LCL-161, reduces survival in aggressive MYC-driven lymphoma while promoting susceptibility to endotoxic shock. Oncogenesis. 2016;5:e216 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5d
Chen S, Wang C, Yeo S, Liang C, Okamoto T, Sun S, et al. Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model. Genes Dev. 2016;30:856-69 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1e
Wang G, Liu X, Gaertig M, Li S, Li X. Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis. Proc Natl Acad Sci U S A. 2016;113:3359-64 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Barroso González J, Auclair S, Luan S, Thomas L, Atkins K, Aslan J, et al. PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage. Cell Death Differ. 2016;23:1448-57 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 表 1
Guillot F, Kemppainen S, Lavasseur G, Miettinen P, Laroche S, Tanila H, et al. Brain-Specific Basal and Novelty-Induced Alternations in PI3K-Akt and MAPK/ERK Signaling in a Middle-Aged AβPP/PS1 Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2016;51:1157-73 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 4a
Xu J, Zhou L, Ji L, Chen F, Fortmann K, Zhang K, et al. The REGγ-proteasome forms a regulatory circuit with IκBÉ› and NFκB in experimental colitis. Nat Commun. 2016;7:10761 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Wang P, Zhang X, Luo P, Jiang X, Zhang P, Guo J, et al. Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling. Nat Commun. 2016;7:10592 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6
Xiao J, Shao L, Shen J, Jiang W, Feng Y, Zheng P, et al. Effects of ketanserin on experimental colitis in mice and macrophage function. Int J Mol Med. 2016;37:659-68 pubmed 出版商
  • 免疫印迹; 人类; 图 s1a
Cott C, Thuenauer R, Landi A, Kühn K, Juillot S, Imberty A, et al. Pseudomonas aeruginosa lectin LecB inhibits tissue repair processes by triggering β-catenin degradation. Biochim Biophys Acta. 2016;1863:1106-18 pubmed 出版商
  • 免疫印迹; 小鼠
Däbritz J, Judd L, Chalinor H, Menheniott T, Giraud A. Altered gp130 signalling ameliorates experimental colitis via myeloid cell-specific STAT3 activation and myeloid-derived suppressor cells. Sci Rep. 2016;6:20584 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 7
  • 免疫印迹; 小鼠; 图 8
Jean Charles P, Zhang L, Wu J, Han S, Brian L, Freedman N, et al. Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation. J Biol Chem. 2016;291:7450-64 pubmed 出版商
  • 免疫印迹; 人类; 图 5h
Capell B, Drake A, Zhu J, Shah P, Dou Z, Dorsey J, et al. MLL1 is essential for the senescence-associated secretory phenotype. Genes Dev. 2016;30:321-36 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Kishi N, MacDonald J, Ye J, Molyneaux B, Azim E, Macklis J. Reduction of aberrant NF-κB signalling ameliorates Rett syndrome phenotypes in Mecp2-null mice. Nat Commun. 2016;7:10520 pubmed 出版商
  • 免疫印迹; 人类; 图 2b
Lu S, Natarajan S, Mott J, Kharbanda K, Harrison Findik D. Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway. PLoS ONE. 2016;11:e0147474 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Ding X, Pan L, Wang Y, Xu Q. Baicalin exerts protective effects against lipopolysaccharide-induced acute lung injury by regulating the crosstalk between the CX3CL1-CX3CR1 axis and NF-κB pathway in CX3CL1-knockout mice. Int J Mol Med. 2016;37:703-15 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2b
Liu H, Shi H, Huang F, Peterson K, Wu H, Lan Y, et al. Astragaloside IV inhibits microglia activation via glucocorticoid receptor mediated signaling pathway. Sci Rep. 2016;6:19137 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Ai L, Xu Q, Wu C, Wang X, Chen Z, Su D, et al. A20 Attenuates FFAs-induced Lipid Accumulation in Nonalcoholic Steatohepatitis. Int J Biol Sci. 2015;11:1436-46 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4C
Ni Y, Nagashimada M, Zhuge F, Zhan L, Nagata N, Tsutsui A, et al. Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. Sci Rep. 2015;5:17192 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Yen Y, Hsiao J, Jiang S, Chang J, Wang S, Shen Y, et al. Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin β1. Oncotarget. 2015;6:41837-55 pubmed 出版商
  • 免疫印迹; 人类; 1:100; 图 s7
Hoshino A, Costa Silva B, Shen T, Rodrigues G, Hashimoto A, Tesic Mark M, et al. Tumour exosome integrins determine organotropic metastasis. Nature. 2015;527:329-35 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1c
Lee D, Goldberg A. Muscle Wasting in Fasting Requires Activation of NF-κB and Inhibition of AKT/Mechanistic Target of Rapamycin (mTOR) by the Protein Acetylase, GCN5. J Biol Chem. 2015;290:30269-79 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Dumas A, Lê Bury G, Marie Anaïs F, Herit F, Mazzolini J, Guilbert T, et al. The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking. J Cell Biol. 2015;211:359-72 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 s4a
Gruosso T, Garnier C, Abélanet S, Kieffer Y, Lemesre V, Bellanger D, et al. MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas. Nat Commun. 2015;6:8583 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
Yao X, Carlson D, Sun Y, Ma L, Wolf S, Minei J, et al. Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model. PLoS ONE. 2015;10:e0139416 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 3b
Singh S, Chand H, Gundavarapu S, Saeed A, Langley R, Tesfaigzi Y, et al. HIF-1α Plays a Critical Role in the Gestational Sidestream Smoke-Induced Bronchopulmonary Dysplasia in Mice. PLoS ONE. 2015;10:e0137757 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4a
Wang J, Hua W, Huang S, Fan K, Takeshima L, Mao Y, et al. RASSF8 regulates progression of cutaneous melanoma through nuclear factor-κb. Oncotarget. 2015;6:30165-77 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1
Nakamura R, Sene A, Santeford A, Gdoura A, Kubota S, Zapata N, et al. IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis. Nat Commun. 2015;6:7847 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
He J, Quintana M, Sullivan J, L Parry T, J Grevengoed T, Schisler J, et al. MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet. Cardiovasc Diabetol. 2015;14:97 pubmed 出版商
  • 免疫印迹; 人类; 图 3d
Oteiza A, Mechti N. Control of FoxO4 Activity and Cell Survival by TRIM22 Directs TLR3-Stimulated Cells Toward IFN Type I Gene Induction or Apoptosis. J Interferon Cytokine Res. 2015;35:859-74 pubmed 出版商
  • 流式细胞仪; 人类; 图 6c
Trinh B, Barengo N, Kim S, Lee J, Zweidler McKay P, Naora H. The homeobox gene DLX4 regulates erythro-megakaryocytic differentiation by stimulating IL-1β and NF-κB signaling. J Cell Sci. 2015;128:3055-67 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2
Yan S, Xu Z, Lou F, Zhang L, Ke F, Bai J, et al. NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis. Nat Commun. 2015;6:7652 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Wang Y, Lian Q, Yang B, Yan S, Zhou H, He L, et al. TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING. PLoS Pathog. 2015;11:e1005012 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Jin X, Yao T, Zhou Z, Zhu J, Zhang S, Hu W, et al. Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway. Biomed Res Int. 2015;2015:732450 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Yi M, Zhang E, Baek H, Kim S, Shin N, Kang J, et al. Growth Differentiation Factor 15 Expression in Astrocytes After Excitotoxic Lesion in the Mouse Hippocampus. Exp Neurobiol. 2015;24:133-8 pubmed 出版商
  • 免疫印迹; 小鼠
Krokowski D, Jobava R, Guan B, Farabaugh K, Wu J, Majumder M, et al. Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity. J Biol Chem. 2015;290:17822-37 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 8
Callaway J, Smith S, McKinnon K, de Silva A, Crowe J, Ting J. Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection. J Biol Chem. 2015;290:17306-20 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s1
Moiseeva O, Lessard F, Acevedo Aquino M, Vernier M, Tsantrizos Y, Ferbeyre G. Mutant lamin A links prophase to a p53 independent senescence program. Cell Cycle. 2015;14:2408-21 pubmed 出版商
  • 免疫印迹; 人类
Greenfeld H, Takasaki K, Walsh M, Ersing I, Bernhardt K, Ma Y, et al. TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation. PLoS Pathog. 2015;11:e1004890 pubmed 出版商
  • 免疫印迹; 人类; 图 9
Wang Z, Cao C, Huang L, Ke Z, Luo C, Lin Z, et al. EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway. Oncotarget. 2015;6:14191-208 pubmed
  • 免疫印迹; 人类; 图 3
Sahu G, Farley K, El Hage N, Aiamkitsumrit B, Fassnacht R, Kashanchi F, et al. Cocaine promotes both initiation and elongation phase of HIV-1 transcription by activating NF-κB and MSK1 and inducing selective epigenetic modifications at HIV-1 LTR. Virology. 2015;483:185-202 pubmed 出版商
  • 免疫印迹; 人类
Katanov C, Lerrer S, Liubomirski Y, Leider Trejo L, Meshel T, Bar J, et al. Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-? and the NF-?B pathway. Stem Cell Res Ther. 2015;6:87 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2
Lin A, Beasley F, Olson J, Keller N, Shalwitz R, Hannan T, et al. Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection. PLoS Pathog. 2015;11:e1004818 pubmed 出版商
  • 免疫印迹; 人类
Willy J, Young S, Stevens J, Masuoka H, Wek R. CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis. Mol Biol Cell. 2015;26:2190-204 pubmed 出版商
  • 免疫印迹; 人类; 1:2500; 图 5a
Koizume S, Ito S, Nakamura Y, Yoshihara M, Furuya M, Yamada R, et al. Lipid starvation and hypoxia synergistically activate ICAM1 and multiple genes in an Sp1-dependent manner to promote the growth of ovarian cancer. Mol Cancer. 2015;14:77 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Wang W, Huang X, Xin H, Fu M, Xue A, Wu Z. TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase. J Biol Chem. 2015;290:13372-85 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Ailenberg M, Di Ciano Oliveira C, Szaszi K, Dan Q, Rozycki M, Kapus A, et al. Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-κB activation. Br J Pharmacol. 2015;172:3748-63 pubmed 出版商
  • 免疫印迹; 人类
Liu Z, Jiang C, Zhang J, Liu B, Du Q. Resveratrol inhibits inflammation and ameliorates insulin resistant endothelial dysfunction via regulation of AMP-activated protein kinase and sirtuin 1 activities. J Diabetes. 2016;8:324-35 pubmed 出版商
  • 免疫印迹; 小鼠
Bao M, Cai Z, Zhang X, Li L, Liu X, Wan N, et al. Dickkopf-3 protects against cardiac dysfunction and ventricular remodelling following myocardial infarction. Basic Res Cardiol. 2015;110:25 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 表 s2
Fallahi Sichani M, Moerke N, Niepel M, Zhang T, Gray N, Sorger P. Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis. Mol Syst Biol. 2015;11:797 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Lavoz C, Alique M, Rodrígues Díez R, Pato J, Keri G, Mezzano S, et al. Gremlin regulates renal inflammation via the vascular endothelial growth factor receptor 2 pathway. J Pathol. 2015;236:407-20 pubmed 出版商
  • 免疫印迹; 人类
Coon B, Baeyens N, Han J, Budatha M, Ross T, Fang J, et al. Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. J Cell Biol. 2015;208:975-86 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Woods S, Waite A, O Dea K, Halford P, Takata M, Wilson M. Kinetic profiling of in vivo lung cellular inflammatory responses to mechanical ventilation. Am J Physiol Lung Cell Mol Physiol. 2015;308:L912-21 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s5
  • 免疫印迹; 小鼠; 1:1000; 图 s4
Chen W, Wu J, Li L, Zhang Z, Ren J, Liang Y, et al. Ppm1b negatively regulates necroptosis through dephosphorylating Rip3. Nat Cell Biol. 2015;17:434-44 pubmed 出版商
  • 免疫印迹; 小鼠; 图 10A
Pone E, Lam T, Lou Z, Wang R, Chen Y, Liu D, et al. B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses. J Immunol. 2015;194:3065-78 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Pannu J, Belle J, Forster M, Duerr C, Shen S, Kane L, et al. Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation. PLoS ONE. 2015;10:e0117304 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3a
Singh V, Wooten A, Jackson J, Maggirwar S, Kiebala M. Investigating the role of ankyrin-rich membrane spanning protein in human immunodeficiency virus type-1 Tat-induced microglia activation. J Neurovirol. 2015;21:186-98 pubmed 出版商
  • 免疫印迹; 人类; 图 5
de la Rica L, García Gómez A, Comet N, Rodríguez Ubreva J, Ciudad L, Vento Tormo R, et al. NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation. Genome Biol. 2015;16:2 pubmed 出版商
  • 免疫印迹; 人类
Zanotto Filho A, Braganhol E, Klafke K, Figueiró F, Terra S, Paludo F, et al. Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. Cancer Lett. 2015;358:220-31 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4
Liu C, Yu Y, Liu F, Wei X, Wrobel J, Gunawardena H, et al. A chromatin activity-based chemoproteomic approach reveals a transcriptional repressome for gene-specific silencing. Nat Commun. 2014;5:5733 pubmed 出版商
  • 免疫印迹; 小鼠
Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, et al. Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B. J Biol Chem. 2015;290:1269-80 pubmed 出版商
  • 免疫印迹; 人类
Kong B, Cho Y, Lee E. G protein-coupled estrogen receptor-1 is involved in the protective effect of protocatechuic aldehyde against endothelial dysfunction. PLoS ONE. 2014;9:e113242 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
  • 免疫组化-石蜡切片; 大鼠
Fukuda M, Aoki T, Manabe T, Maekawa A, Shirakawa T, Kataoka H, et al. Exacerbation of intracranial aneurysm and aortic dissection in hypertensive rat treated with the prostaglandin F-receptor antagonist AS604872. J Pharmacol Sci. 2014;126:230-42 pubmed
  • 免疫印迹; 人类; 1:1000; 图 5
Lei Q, Qiang F, Chao D, Di W, Guoqian Z, Bo Y, et al. Amelioration of hypoxia and LPS-induced intestinal epithelial barrier dysfunction by emodin through the suppression of the NF-κB and HIF-1α signaling pathways. Int J Mol Med. 2014;34:1629-39 pubmed 出版商
  • 免疫印迹; 人类
Brandau S, Jakob M, Bruderek K, Bootz F, Giebel B, Radtke S, et al. Mesenchymal stem cells augment the anti-bacterial activity of neutrophil granulocytes. PLoS ONE. 2014;9:e106903 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
  • 免疫印迹; 小鼠; 1:1000
Dou W, Zhang J, Ren G, Ding L, Sun A, Deng C, et al. Mangiferin attenuates the symptoms of dextran sulfate sodium-induced colitis in mice via NF-κB and MAPK signaling inactivation. Int Immunopharmacol. 2014;23:170-8 pubmed 出版商
  • 免疫印迹; 小鼠
Huang S, Lee C, Wang H, Chang Y, Lin C, Chen C, et al. 6-Dehydrogingerdione restrains lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages. J Agric Food Chem. 2014;62:9171-9 pubmed 出版商
  • 免疫印迹; 小鼠; 1:100
Nteeba J, Ganesan S, Keating A. Progressive obesity alters ovarian folliculogenesis with impacts on pro-inflammatory and steroidogenic signaling in female mice. Biol Reprod. 2014;91:86 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L, et al. RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature. 2014;513:90-4 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Yu B, Chang J, Liu Y, Li J, Kevork K, Al Hezaimi K, et al. Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-?B. Nat Med. 2014;20:1009-17 pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Ye S, Li Z, Luo D, Huang B, Chen Y, Zhang X, et al. Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma. Oncotarget. 2014;5:5439-52 pubmed
  • 免疫印迹; 小鼠
König H, Coughlan K, Kinsella S, Breen B, Prehn J. The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes. Neurobiol Dis. 2014;70:99-107 pubmed 出版商
  • 免疫印迹; 人类; 图 3, 4, 5
Kobayashi T, Masoumi K, Massoumi R. Deubiquitinating activity of CYLD is impaired by SUMOylation in neuroblastoma cells. Oncogene. 2015;34:2251-60 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6c
Billon C, Canaple L, Fleury S, Deloire A, Beylot M, Dombrowicz D, et al. TR? protects against atherosclerosis in male mice: identification of a novel anti-inflammatory property for TR? in mice. Endocrinology. 2014;155:2735-45 pubmed 出版商
  • 免疫印迹; 人类
Liu B, Cao Y, Huizinga T, Hafler D, Toes R. TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells. Eur J Immunol. 2014;44:2121-9 pubmed 出版商
  • 免疫印迹; 小鼠
Kumar V, Palermo R, Talora C, Campese A, Checquolo S, Bellavia D, et al. Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia. Leukemia. 2014;28:2324-35 pubmed 出版商
  • 免疫印迹; 小鼠
Ballak D, van Essen P, van Diepen J, Jansen H, Hijmans A, Matsuguchi T, et al. MAP3K8 (TPL2/COT) affects obesity-induced adipose tissue inflammation without systemic effects in humans and in mice. PLoS ONE. 2014;9:e89615 pubmed 出版商
  • 免疫印迹; 人类
Olesen J, Gliemann L, Biensø R, Schmidt J, Hellsten Y, Pilegaard H. Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men. J Physiol. 2014;592:1873-86 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3a
Piao H, Yuan Y, Wang M, Sun Y, Liang H, Ma L. ?-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-?B signalling. Nat Cell Biol. 2014;16:245-54 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Dorn C, Engelmann J, Saugspier M, Koch A, Hartmann A, Müller M, et al. Increased expression of c-Jun in nonalcoholic fatty liver disease. Lab Invest. 2014;94:394-408 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Zhang Q, Pan Y, Wang R, Kang L, Xue Q, Wang X, et al. Quercetin inhibits AMPK/TXNIP activation and reduces inflammatory lesions to improve insulin signaling defect in the hypothalamus of high fructose-fed rats. J Nutr Biochem. 2014;25:420-8 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Yoshida T, Yamashita M, Horimai C, Hayashi M. Deletion of Krüppel-like factor 4 in endothelial and hematopoietic cells enhances neointimal formation following vascular injury. J Am Heart Assoc. 2014;3:e000622 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4
Al Sawaf O, Fragoulis A, Rosen C, Kan Y, Sönmez T, Pufe T, et al. Nrf2 protects against TWEAK-mediated skeletal muscle wasting. Sci Rep. 2014;4:3625 pubmed 出版商
  • 免疫印迹; 小鼠
Ekman M, Bhattachariya A, Dahan D, Uvelius B, Albinsson S, Swärd K. Mir-29 repression in bladder outlet obstruction contributes to matrix remodeling and altered stiffness. PLoS ONE. 2013;8:e82308 pubmed 出版商
  • 免疫印迹; 人类; 图 6D
Bohonowych J, Hance M, Nolan K, DEFEE M, Parsons C, Isaacs J. Extracellular Hsp90 mediates an NF-?B dependent inflammatory stromal program: implications for the prostate tumor microenvironment. Prostate. 2014;74:395-407 pubmed 出版商
  • 免疫印迹; 人类
Zhan Z, Xie X, Cao H, Zhou X, Zhang X, Fan H, et al. Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination. Autophagy. 2014;10:257-68 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Bhaskar K, Maphis N, Xu G, Varvel N, Kokiko Cochran O, Weick J, et al. Microglial derived tumor necrosis factor-? drives Alzheimer's disease-related neuronal cell cycle events. Neurobiol Dis. 2014;62:273-85 pubmed 出版商
  • 免疫印迹; 人类
Song J, Peng X, Ji M, Ai M, Zhang J, Dong W. Hugl-1 induces apoptosis in esophageal carcinoma cells both in vitro and in vivo. World J Gastroenterol. 2013;19:4127-36 pubmed 出版商
  • 免疫组化; 小鼠
  • 免疫印迹; 小鼠
Tan C, Tan E, Luo B, Huang C, Loo J, Choong C, et al. SMAD3 deficiency promotes inflammatory aortic aneurysms in angiotensin II-infused mice via activation of iNOS. J Am Heart Assoc. 2013;2:e000269 pubmed 出版商
  • 免疫印迹; 小鼠
Dai J, Shen D, Bian Z, Zhou H, Gan H, Zong J, et al. IKKi deficiency promotes pressure overload-induced cardiac hypertrophy and fibrosis. PLoS ONE. 2013;8:e53412 pubmed 出版商
  • 免疫印迹; 小鼠
Day R, Cavaglieri R, Feliers D. Apelin retards the progression of diabetic nephropathy. Am J Physiol Renal Physiol. 2013;304:F788-800 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Sykes L, Lee Y, Khanjani S, MacIntyre D, Yap X, Ponnampalam S, et al. Chemoattractant receptor homologous to the T helper 2 cell (CRTH2) is not expressed in human amniocytes and myocytes. PLoS ONE. 2012;7:e50734 pubmed 出版商
Lee J, Yu K, Lee B, Kang I, Kim J, Jung E, et al. GATA4-dependent regulation of the secretory phenotype via MCP-1 underlies lamin A-mediated human mesenchymal stem cell aging. Exp Mol Med. 2018;50:63 pubmed 出版商
Ebelt N, Kaoud T, Edupuganti R, Van Ravenstein S, Dalby K, Van Den Berg C. A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib. Oncotarget. 2017;8:104894-104912 pubmed 出版商
Rao S, Sigl V, Wimmer R, Novatchkova M, Jais A, Wagner G, et al. RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer. Genes Dev. 2017;31:2099-2112 pubmed 出版商
Fischer J, Otten V, Kober M, Drees C, Rosenbaum M, Schmickl M, et al. A20 Restrains Thymic Regulatory T Cell Development. J Immunol. 2017;199:2356-2365 pubmed 出版商
Payen V, Hsu M, Rädecke K, Wyart E, Vazeille T, Bouzin C, et al. Monocarboxylate Transporter MCT1 Promotes Tumor Metastasis Independently of Its Activity as a Lactate Transporter. Cancer Res. 2017;77:5591-5601 pubmed 出版商
Xu J, Xu X, Wang B, Ma Y, Zhang L, Xu H, et al. Nuclear carbonic anhydrase 6B associates with PRMT5 to epigenetically promote IL-12 expression in innate response. Proc Natl Acad Sci U S A. 2017;114:8620-8625 pubmed 出版商
Zou Z, Meng Z, Ma C, Liang D, Sun R, Lan K. Guanylate-Binding Protein 1 Inhibits Nuclear Delivery of Kaposi's Sarcoma-Associated Herpesvirus Virions by Disrupting Formation of Actin Filament. J Virol. 2017;91: pubmed 出版商
Brady G, Haas D, Farrell P, Pichlmair A, Bowie A. Molluscum Contagiosum Virus Protein MC005 Inhibits NF-κB Activation by Targeting NEMO-Regulated IκB Kinase Activation. J Virol. 2017;91: pubmed 出版商
Liao X, Feng B, Zhang D, Liu P, Zhou X, Li R, et al. The Sirt6 gene: Does it play a role in tooth development?. PLoS ONE. 2017;12:e0174255 pubmed 出版商
Li R, Fang F, Jiang M, Wang C, Ma J, Kang W, et al. STAT3 and NF-κB are Simultaneously Suppressed in Dendritic Cells in Lung Cancer. Sci Rep. 2017;7:45395 pubmed 出版商
Choe J, Kim S. Melittin inhibits osteoclast formation through the downregulation of the RANKL-RANK signaling pathway and the inhibition of interleukin-1? in murine macrophages. Int J Mol Med. 2017;39:539-548 pubmed 出版商
Ganesan R, Hos N, Gutierrez S, Fischer J, Stepek J, Daglidu E, et al. Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy. PLoS Pathog. 2017;13:e1006227 pubmed 出版商
Diamanti M, Gupta J, Bennecke M, De Oliveira T, Ramakrishnan M, Braczynski A, et al. IKK? controls ATG16L1 degradation to prevent ER stress during inflammation. J Exp Med. 2017;214:423-437 pubmed 出版商
Prince P, Fischerman L, Toblli J, Fraga C, Galleano M. LPS-induced renal inflammation is prevented by (-)-epicatechin in rats. Redox Biol. 2017;11:342-349 pubmed 出版商
Kim H, Shin C, Lee H, Choi K, Nam D, Ohn T, et al. MicroRNA-1908-5p contributes to the oncogenic function of the splicing factor SRSF3. Oncotarget. 2017;8:8342-8355 pubmed 出版商
Henry W, Laszewski T, Tsang T, Beca F, Beck A, McAllister S, et al. Aspirin Suppresses Growth in PI3K-Mutant Breast Cancer by Activating AMPK and Inhibiting mTORC1 Signaling. Cancer Res. 2017;77:790-801 pubmed 出版商
Liu W, Guo W, Shen L, Chen Z, Luo Q, Luo X, et al. T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice. Oncotarget. 2017;8:7586-7597 pubmed 出版商
Lee H, Zhang D, Zhu Z, Dela Cruz C, Jin Y. Epithelial cell-derived microvesicles activate macrophages and promote inflammation via microvesicle-containing microRNAs. Sci Rep. 2016;6:35250 pubmed 出版商
Joseph J, Ametepe E, Haribabu N, Agbayani G, Krishnan L, Blais A, et al. Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium. Nat Commun. 2016;7:12748 pubmed 出版商
Sun H, Wang W, Han P, Shao M, Song G, Du H, et al. Astragaloside IV ameliorates renal injury in db/db mice. Sci Rep. 2016;6:32545 pubmed 出版商
Perez M, Peinado Serrano J, García Heredia J, Felipe Abrio I, Tous C, Ferrer I, et al. Efficacy of bortezomib in sarcomas with high levels of MAP17 (PDZK1IP1). Oncotarget. 2016;7:67033-67046 pubmed 出版商
Park J, Lee H, Kim S, Yang S. The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. Oncotarget. 2016;7:58405-58417 pubmed 出版商
Minter M, Moore Z, Zhang M, Brody K, Jones N, Shultz S, et al. Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype. Acta Neuropathol Commun. 2016;4:72 pubmed 出版商
Tsai S, Huang P, Hsu Y, Peng Y, Lee C, Wang J, et al. Inhibition of hypoxia inducible factor-1α attenuates abdominal aortic aneurysm progression through the down-regulation of matrix metalloproteinases. Sci Rep. 2016;6:28612 pubmed 出版商
Wang H, Gao K, Wen K, Allen I, Li G, Zhang W, et al. Lactobacillus rhamnosus GG modulates innate signaling pathway and cytokine responses to rotavirus vaccine in intestinal mononuclear cells of gnotobiotic pigs transplanted with human gut microbiota. BMC Microbiol. 2016;16:109 pubmed 出版商
Rodrígues Díez R, González Guerrero C, Ocaña Salceda C, Rodrigues Díez R, Egido J, Ortiz A, et al. Calcineurin inhibitors cyclosporine A and tacrolimus induce vascular inflammation and endothelial activation through TLR4 signaling. Sci Rep. 2016;6:27915 pubmed 出版商
Xiang S, Zeng Y, Xiong B, Qin Y, Huang X, Jiang Y, et al. Transforming growth factor beta 1 induced endothelin-1 release is peroxisome proliferator-activated receptor gamma dependent in A549 cells. J Inflamm (Lond). 2016;13:19 pubmed 出版商
Shang J, Li L, Wang X, Pan H, Liu S, He R, et al. Disruption of Tumor Necrosis Factor Receptor-Associated Factor 5 Exacerbates Murine Experimental Colitis via Regulating T Helper Cell-Mediated Inflammation. Mediators Inflamm. 2016;2016:9453745 pubmed 出版商
Kong B, Im S, Lee Y, Cho Y, Do Y, Byun J, et al. Vasculoprotective Effects of 3-Hydroxybenzaldehyde against VSMCs Proliferation and ECs Inflammation. PLoS ONE. 2016;11:e0149394 pubmed 出版商
Etemadi N, Chopin M, Anderton H, Tanzer M, Rickard J, Abeysekera W, et al. TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1. elife. 2015;4: pubmed 出版商
Dong M, Li M, Chen J, Fu T, Lin K, Ye G, et al. Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production. Inflammation. 2016;39:687-99 pubmed 出版商
Kastrati I, LITOSH V, Zhao S, Alvarez M, Thatcher G, Frasor J. A novel aspirin prodrug inhibits NFκB activity and breast cancer stem cell properties. BMC Cancer. 2015;15:845 pubmed 出版商
Van Hée V, Pérez Escuredo J, Cacace A, Copetti T, Sonveaux P. Lactate does not activate NF-κB in oxidative tumor cells. Front Pharmacol. 2015;6:228 pubmed 出版商
Holland A, Hyatt H, Smuder A, Sollanek K, Morton A, Roberts M, et al. Influence of endurance exercise training on antioxidant enzymes, tight junction proteins, and inflammatory markers in the rat ileum. BMC Res Notes. 2015;8:514 pubmed 出版商
Nagaraja A, Dorniak P, Sadaoui N, Kang Y, Lin T, Armaiz Pena G, et al. Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis. Oncogene. 2016;35:2390-7 pubmed 出版商
Qian H, Deng X, Huang Z, Wei J, Ding C, Feng R, et al. An HNF1α-regulated feedback circuit modulates hepatic fibrogenesis via the crosstalk between hepatocytes and hepatic stellate cells. Cell Res. 2015;25:930-45 pubmed 出版商
Yin T, He S, Shen G, Ye T, Guo F, Wang Y. Dopamine receptor antagonist thioridazine inhibits tumor growth in a murine breast cancer model. Mol Med Rep. 2015;12:4103-4108 pubmed 出版商
Chen W, Ebelt N, Stracker T, Xhemalce B, Van Den Berg C, Miller K. ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion. elife. 2015;4: pubmed 出版商
Zheng N, Wang D, Ming H, Zhang H, Yu X. BAFF promotes proliferation of human mesangial cells through interaction with BAFF-R. BMC Nephrol. 2015;16:72 pubmed 出版商
Hirata B, Banin R, Dornellas A, de Andrade I, Zemdegs J, Caperuto L, et al. Ginkgo biloba extract improves insulin signaling and attenuates inflammation in retroperitoneal adipose tissue depot of obese rats. Mediators Inflamm. 2015;2015:419106 pubmed 出版商
Datta Mitra A, Kundu Raychaudhuri S, Mitra A, Raychaudhuri S. Cross talk between neuroregulatory molecule and monocyte: nerve growth factor activates the inflammasome. PLoS ONE. 2015;10:e0121626 pubmed 出版商
Farnebo L, Shahangian A, Lee Y, Shin J, Scheeren F, Sunwoo J. Targeting Toll-like receptor 2 inhibits growth of head and neck squamous cell carcinoma. Oncotarget. 2015;6:9897-907 pubmed
Wang X, Wang Z, Sidhu P, Desai U, Zhou Q. 6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di- and polyhydroxylated flavones in kidney mesangial cells. PLoS ONE. 2015;10:e0116409 pubmed 出版商
Kinugasa H, Whelan K, Tanaka K, Natsuizaka M, Long A, Guo A, et al. Mitochondrial SOD2 regulates epithelial-mesenchymal transition and cell populations defined by differential CD44 expression. Oncogene. 2015;34:5229-39 pubmed 出版商
Chen X, Zhang X, Wang Y, Lei H, Su H, Zeng J, et al. Inhibition of immunoproteasome reduces infarction volume and attenuates inflammatory reaction in a rat model of ischemic stroke. Cell Death Dis. 2015;6:e1626 pubmed 出版商
Prabhavathy D, Subramanian C, Karunagaran D. Re-expression of HPV16 E2 in SiHa (human cervical cancer) cells potentiates NF-κB activation induced by TNF-α concurrently increasing senescence and survival. Biosci Rep. 2015;35: pubmed 出版商
Harada M, Kamimura D, Arima Y, Kohsaka H, Nakatsuji Y, Nishida M, et al. Temporal expression of growth factors triggered by epiregulin regulates inflammation development. J Immunol. 2015;194:1039-46 pubmed 出版商
Rickard J, Anderton H, Etemadi N, Nachbur U, Darding M, Peltzer N, et al. TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice. elife. 2014;3: pubmed 出版商
Müller I, Beissert S, Kulms D. Anti-apoptotic NF-κB and "gain of function" mutp53 in concert act pro-apoptotic in response to UVB+IL-1 via enhanced TNF production. J Invest Dermatol. 2015;135:851-860 pubmed 出版商
Yue Y, Wang Y, Li D, Song Z, Jiao H, Lin H. A central role for the mammalian target of rapamycin in LPS-induced anorexia in mice. J Endocrinol. 2015;224:37-47 pubmed 出版商
Zhang X, Shi Y, Weng Y, Lai Q, Luo T, Zhao J, et al. The truncate mutation of Notch2 enhances cell proliferation through activating the NF-κB signal pathway in the diffuse large B-cell lymphomas. PLoS ONE. 2014;9:e108747 pubmed 出版商
Derksen A, Hensel A, Hafezi W, Herrmann F, Schmidt T, Ehrhardt C, et al. 3-O-galloylated procyanidins from Rumex acetosa L. inhibit the attachment of influenza A virus. PLoS ONE. 2014;9:e110089 pubmed 出版商
Liu Y, Liu X, Hao W, Decker Y, Schomburg R, Fülöp L, et al. IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology. J Neurosci. 2014;34:12982-99 pubmed 出版商
Shoda T, Futamura K, Kobayashi F, Saito H, Matsumoto K, Matsuda A. Expression of thymus and activation-regulated chemokine (TARC) by human dermal cells, but not epidermal keratinocytes. J Dermatol Sci. 2014;76:90-5 pubmed 出版商
Zagórska A, Través P, Lew E, Dransfield I, Lemke G. Diversification of TAM receptor tyrosine kinase function. Nat Immunol. 2014;15:920-8 pubmed 出版商
Parker K, Sinha P, Horn L, Clements V, Yang H, Li J, et al. HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells. Cancer Res. 2014;74:5723-33 pubmed 出版商
Sun Y, Li J, Xiao N, Wang M, Kou J, Qi L, et al. Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1. Pharmacol Res. 2014;89:19-28 pubmed 出版商
Parhira S, Yang Z, Zhu G, Chen Q, Zhou B, Wang Y, et al. In vitro anti-influenza virus activities of a new lignan glycoside from the latex of Calotropis gigantea. PLoS ONE. 2014;9:e104544 pubmed 出版商
Tseng F, Liou D, Tsai M, Huang W, Cheng H. Cytoprotective and anti-inflammatory effects of PAL31 overexpression in glial cells. J Biomed Sci. 2014;21:60 pubmed 出版商
Skalniak L, Dziendziel M, Jura J. MCPIP1 contributes to the toxicity of proteasome inhibitor MG-132 in HeLa cells by the inhibition of NF-?B. Mol Cell Biochem. 2014;395:253-63 pubmed 出版商
Yang J, Rui B, Chen C, Chen H, Xu T, Xu W, et al. Acetylsalicylic acid enhances the anti-inflammatory effect of fluoxetine through inhibition of NF-?B, p38-MAPK and ERK1/2 activation in lipopolysaccharide-induced BV-2 microglia cells. Neuroscience. 2014;275:296-304 pubmed 出版商
Wong S, Chan S, Wong W, Wong P, Lai M. Andrographolide attenuates interleukin-1?-stimulated upregulation of chemokine CCL5 and glial fibrillary acidic protein in astrocytes. Neuroreport. 2014;25:881-6 pubmed 出版商
GAO P, Tao N, Ma Q, Fan W, Ni C, Wang H, et al. DH332, a synthetic β-carboline alkaloid, inhibits B cell lymphoma growth by activation of the caspase family. Asian Pac J Cancer Prev. 2014;15:3901-6 pubmed
Wang B, Yang G, Liang X, Zhu M, Du M. Grape seed extract prevents skeletal muscle wasting in interleukin 10 knockout mice. BMC Complement Altern Med. 2014;14:162 pubmed 出版商
Li H, Wang D. Streptococcus mutans wall-associated protein A promotes TLR4-induced dendritic cell maturation. Scand J Immunol. 2014;80:121-6 pubmed 出版商
Takeda Y, Nara H, Araki A, Asao H. Human peripheral neutrophils express functional IL-21 receptors. Inflammation. 2014;37:1521-32 pubmed 出版商
Kannan K, Coarfa C, Rajapakshe K, Hawkins S, Matzuk M, Milosavljevic A, et al. CDKN2D-WDFY2 is a cancer-specific fusion gene recurrent in high-grade serous ovarian carcinoma. PLoS Genet. 2014;10:e1004216 pubmed 出版商
Woo J, Gu W, Kim K, Jang S, Han M, Kim D. Lactobacillus pentosus var. plantarum C29 ameliorates memory impairment and inflammaging in a D-galactose-induced accelerated aging mouse model. Anaerobe. 2014;27:22-6 pubmed 出版商
Leibovich Rivkin T, Liubomirski Y, Meshel T, Abashidze A, Brisker D, Solomon H, et al. The inflammatory cytokine TNF? cooperates with Ras in elevating metastasis and turns WT-Ras to a tumor-promoting entity in MCF-7 cells. BMC Cancer. 2014;14:158 pubmed 出版商
Zhao N, Wang R, Zhou L, Zhu Y, Gong J, Zhuang S. MicroRNA-26b suppresses the NF-?B signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3. Mol Cancer. 2014;13:35 pubmed 出版商
Wattenberg M, Kwilas A, Gameiro S, Dicker A, Hodge J. Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets. Br J Cancer. 2014;110:1472-80 pubmed 出版商
Trojandt S, Reske Kunz A, Bros M. Geldanamycin-mediated inhibition of heat shock protein 90 partially activates dendritic cells, but interferes with their full maturation, accompanied by impaired upregulation of RelB. J Exp Clin Cancer Res. 2014;33:16 pubmed 出版商
Nojiri T, Hosoda H, Tokudome T, Miura K, Ishikane S, Kimura T, et al. Atrial natriuretic peptide inhibits lipopolysaccharide-induced acute lung injury. Pulm Pharmacol Ther. 2014;29:24-30 pubmed 出版商
De Nardo D, Labzin L, Kono H, Seki R, Schmidt S, Beyer M, et al. High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3. Nat Immunol. 2014;15:152-60 pubmed 出版商
Choi J, Devkota S, Sung Y, Lee H. EI24 regulates epithelial-to-mesenchymal transition and tumor progression by suppressing TRAF2-mediated NF-?B activity. Oncotarget. 2013;4:2383-96 pubmed
Watanabe R, Azuma R, Suzuki J, Ogawa M, Itai A, Hirata Y, et al. Inhibition of NF-κB activation by a novel IKK inhibitor reduces the severity of experimental autoimmune myocarditis via suppression of T-cell activation. Am J Physiol Heart Circ Physiol. 2013;305:H1761-71 pubmed 出版商
Wang Y, Liu I, Chiang C, Wu H. Astrocyte elevated gene-1 is associated with metastasis in head and neck squamous cell carcinoma through p65 phosphorylation and upregulation of MMP1. Mol Cancer. 2013;12:109 pubmed 出版商
Yuan X, Zhou Y, Wang W, Li J, Xie G, Zhao Y, et al. Activation of TLR4 signaling promotes gastric cancer progression by inducing mitochondrial ROS production. Cell Death Dis. 2013;4:e794 pubmed 出版商
Yoshida T, Yamashita M, Horimai C, Hayashi M. Smooth muscle-selective inhibition of nuclear factor-?B attenuates smooth muscle phenotypic switching and neointima formation following vascular injury. J Am Heart Assoc. 2013;2:e000230 pubmed 出版商
Hanami K, Nakano K, Saito K, Okada Y, Yamaoka K, Kubo S, et al. Dopamine D2-like receptor signaling suppresses human osteoclastogenesis. Bone. 2013;56:1-8 pubmed 出版商
Skalniak L, Koj A, Jura J. Proteasome inhibitor MG-132 induces MCPIP1 expression. FEBS J. 2013;280:2665-74 pubmed 出版商
Yan S, Wang Y, Yang Q, Li X, Kong X, Zhang N, et al. Low-dose radiation-induced epithelial-mesenchymal transition through NF-?B in cervical cancer cells. Int J Oncol. 2013;42:1801-6 pubmed 出版商
Kempuraj D, Twait E, Williard D, Yuan Z, Meyerholz D, Samuel I. The novel cytokine interleukin-33 activates acinar cell proinflammatory pathways and induces acute pancreatic inflammation in mice. PLoS ONE. 2013;8:e56866 pubmed 出版商
Wu H, Tao N, Liu X, Li X, Tang J, Ma C, et al. Polysaccharide from Lentinus edodes inhibits the immunosuppressive function of myeloid-derived suppressor cells. PLoS ONE. 2012;7:e51751 pubmed 出版商
Zhao X, Rong L, Zhao X, Li X, Liu X, Deng J, et al. TNF signaling drives myeloid-derived suppressor cell accumulation. J Clin Invest. 2012;122:4094-104 pubmed 出版商
Knights A, Fucíková J, Pasam A, Koernig S, Cebon J. Inhibitor of apoptosis protein (IAP) antagonists demonstrate divergent immunomodulatory properties in human immune subsets with implications for combination therapy. Cancer Immunol Immunother. 2013;62:321-35 pubmed 出版商
Ma Y, Zhang X, Bao H, Mi S, Cai W, Yan H, et al. Toll-like receptor (TLR) 2 and TLR4 differentially regulate doxorubicin induced cardiomyopathy in mice. PLoS ONE. 2012;7:e40763 pubmed 出版商
Ruan J, Liao Y, Lua I, Li M, Hsu C, Chen J. Human pituitary tumor-transforming gene 1 overexpression reinforces oncogene-induced senescence through CXCR2/p21 signaling in breast cancer cells. Breast Cancer Res. 2012;14:R106 pubmed 出版商
Zhou Y, Fang L, Jiang L, Wen P, Cao H, He W, et al. Uric acid induces renal inflammation via activating tubular NF-?B signaling pathway. PLoS ONE. 2012;7:e39738 pubmed 出版商
Cai Z, Yang F, Yu L, Yu Z, Jiang L, Wang Q, et al. Activated T cell exosomes promote tumor invasion via Fas signaling pathway. J Immunol. 2012;188:5954-61 pubmed 出版商
Lee Y, Sooranna S, Terzidou V, Christian M, Brosens J, Huhtinen K, et al. Interactions between inflammatory signals and the progesterone receptor in regulating gene expression in pregnant human uterine myocytes. J Cell Mol Med. 2012;16:2487-503 pubmed 出版商
Börner C, Hollt V, Kraus J. Mechanisms of the inhibition of nuclear factor-?B by morphine in neuronal cells. Mol Pharmacol. 2012;81:587-97 pubmed 出版商
Hu P, Chu G, Zhu G, Yang H, Luthringer D, Prins G, et al. Multiplexed quantum dot labeling of activated c-Met signaling in castration-resistant human prostate cancer. PLoS ONE. 2011;6:e28670 pubmed 出版商
Kusano Kitazume A, Sakamoto N, Okuno Y, Sekine Osajima Y, Nakagawa M, Kakinuma S, et al. Identification of novel N-(morpholine-4-carbonyloxy) amidine compounds as potent inhibitors against hepatitis C virus replication. Antimicrob Agents Chemother. 2012;56:1315-23 pubmed 出版商
Sakai Y, Uchida K, Nakayama H. A20 and ABIN-3 possibly promote regression of trehalose 6,6'-dimycolate (TDM)-induced granuloma by interacting with an NF-kappa B signaling protein, TAK-1. Inflamm Res. 2012;61:245-53 pubmed 出版商
Dental C, Florentin J, Aouar B, Gondois Rey F, Durantel D, Baumert T, et al. Hepatitis C virus fails to activate NF-?B signaling in plasmacytoid dendritic cells. J Virol. 2012;86:1090-6 pubmed 出版商
Miyake S, Takahashi N, Sasaki M, Kobayashi S, Tsubota K, Ozawa Y. Vision preservation during retinal inflammation by anthocyanin-rich bilberry extract: cellular and molecular mechanism. Lab Invest. 2012;92:102-9 pubmed 出版商
Cheung H, St Jean M, Beug S, Lejmi Mrad R, LaCasse E, Baird S, et al. SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds. Cell Death Dis. 2011;2:e146 pubmed 出版商
Stairs D, Bayne L, Rhoades B, Vega M, Waldron T, Kalabis J, et al. Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. Cancer Cell. 2011;19:470-83 pubmed 出版商
Kelk P, Abd H, Claesson R, Sandstrom G, Sjostedt A, Johansson A. Cellular and molecular response of human macrophages exposed to Aggregatibacter actinomycetemcomitans leukotoxin. Cell Death Dis. 2011;2:e126 pubmed 出版商
Yen H, Ooka T, Iguchi A, Hayashi T, Sugimoto N, Tobe T. NleC, a type III secretion protease, compromises NF-?B activation by targeting p65/RelA. PLoS Pathog. 2010;6:e1001231 pubmed 出版商
Kwong C, Gilman Sachs A, Beaman K. Tumor-associated a2 vacuolar ATPase acts as a key mediator of cancer-related inflammation by inducing pro-tumorigenic properties in monocytes. J Immunol. 2011;186:1781-9 pubmed 出版商
Xie S, Li J, Wang J, Wu Q, Yang P, Hsu H, et al. IL-17 activates the canonical NF-kappaB signaling pathway in autoimmune B cells of BXD2 mice to upregulate the expression of regulators of G-protein signaling 16. J Immunol. 2010;184:2289-96 pubmed 出版商
Lluis J, Nachbur U, Cook W, Gentle I, Moujalled D, Moulin M, et al. TAK1 is required for survival of mouse fibroblasts treated with TRAIL, and does so by NF-kappaB dependent induction of cFLIPL. PLoS ONE. 2010;5:e8620 pubmed 出版商
Wang H, Syrovets T, Kess D, Büchele B, Hainzl H, Lunov O, et al. Targeting NF-kappa B with a natural triterpenoid alleviates skin inflammation in a mouse model of psoriasis. J Immunol. 2009;183:4755-63 pubmed 出版商
Sun Z, Huang Z, Zhang D. Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response. PLoS ONE. 2009;4:e6588 pubmed 出版商
Solt L, Madge L, May M. NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation. J Biol Chem. 2009;284:27596-608 pubmed 出版商
Yamanaka Y, Tagawa H, Takahashi N, Watanabe A, Guo Y, Iwamoto K, et al. Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer-cell lymphoma/leukemia. Blood. 2009;114:3265-75 pubmed 出版商
Reed J, Leon R, Hall M, Schwertfeger K. Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis. Breast Cancer Res. 2009;11:R21 pubmed 出版商
Liu M, Ju X, Willmarth N, Casimiro M, Ojeifo J, Sakamaki T, et al. Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo. Am J Pathol. 2009;174:1910-20 pubmed 出版商
Milsom M, Schiedlmeier B, Bailey J, Kim M, Li D, Jansen M, et al. Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells. Blood. 2009;113:5111-20 pubmed 出版商
Dai P, Jeong S, Yu Y, Leng T, Wu W, Xie L, et al. Modulation of TLR signaling by multiple MyD88-interacting partners including leucine-rich repeat Fli-I-interacting proteins. J Immunol. 2009;182:3450-60 pubmed 出版商
Yadav U, Subramanyam S, Ramana K. Prevention of endotoxin-induced uveitis in rats by benfotiamine, a lipophilic analogue of vitamin B1. Invest Ophthalmol Vis Sci. 2009;50:2276-82 pubmed 出版商
Luedde T, Heinrichsdorff J, De Lorenzi R, De Vos R, Roskams T, Pasparakis M. IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver. Proc Natl Acad Sci U S A. 2008;105:9733-8 pubmed 出版商
Vince J, Chau D, Callus B, Wong W, Hawkins C, Schneider P, et al. TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. J Cell Biol. 2008;182:171-84 pubmed 出版商
Peiser M, Koeck J, Kirschning C, Wittig B, Wanner R. Human Langerhans cells selectively activated via Toll-like receptor 2 agonists acquire migratory and CD4+T cell stimulatory capacity. J Leukoc Biol. 2008;83:1118-27 pubmed 出版商
Lou H, Kaplowitz N. Glutathione depletion down-regulates tumor necrosis factor alpha-induced NF-kappaB activity via IkappaB kinase-dependent and -independent mechanisms. J Biol Chem. 2007;282:29470-81 pubmed
Suzuki S, Singhirunnusorn P, Mori A, Yamaoka S, Kitajima I, Saiki I, et al. Constitutive activation of TAK1 by HTLV-1 tax-dependent overexpression of TAB2 induces activation of JNK-ATF2 but not IKK-NF-kappaB. J Biol Chem. 2007;282:25177-81 pubmed
Lacasa D, Taleb S, Keophiphath M, Miranville A, Clement K. Macrophage-secreted factors impair human adipogenesis: involvement of proinflammatory state in preadipocytes. Endocrinology. 2007;148:868-77 pubmed
产品信息
SKU号 :
3033S
产品名称 :
磷酸化NF p65(Ser536)(93H1)兔单克隆抗体
规格 :
100微升
Price-(USD) :
274美元
物种x :
H, M, R, Hm, Mk, Pg, (Dg)
应用 :
流式细胞仪
产品种类 :
免疫学和炎症
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
65
宿主 :
靶标 :
NFkB-p65(Ser536)磷酸盐
最初蛋白 :
NFkB-p65
别名 :
MGC131774,NFKB3,Nuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3,RELA,TF65,Transcription factor p65,p65,v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)),v-rel reticuloendotheliosis viral oncogene homolog A (avian),v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。