产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
PDGF Receptor β (28E1) Rabbit mAb
目录 :
3169
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
28E1
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 其他
文章摘录数: 66
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 6b
Bownes L, Williams A, Marayati R, Quinn C, Hutchins S, Stewart J, et al. Serine-Threonine Kinase Receptor-Associated Protein (STRAP) Knockout Decreases the Malignant Phenotype in Neuroblastoma Cell Lines. Cancers (Basel). 2021;13: pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Ostriker A, Xie Y, Chakraborty R, Sizer A, Bai Y, Ding M, et al. TET2 Protects Against Vascular Smooth Muscle Cell Apoptosis and Intimal Thickening in Transplant Vasculopathy. Circulation. 2021;144:455-470 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 4a
Geng G, Liu J, Xu C, Pei Y, Chen L, Mu C, et al. Receptor-mediated mitophagy regulates EPO production and protects against renal anemia. elife. 2021;10: pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 4a
Powell K. Global virus tracker. Nature. 2021;593:160 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2f
Lechertier T, Reynolds L, Kim H, Pedrosa A, Gómez Escudero J, Muñoz Félix J, et al. Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth. Nat Commun. 2020;11:2810 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 1f
Ruscetti M, Morris J, Mezzadra R, Russell J, Leibold J, Romesser P, et al. Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer. Cell. 2020;181:424-441.e21 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 1a
  • 免疫组化; 小鼠; 1:200; 图 5a
  • 免疫印迹; 小鼠; 1:1000; 图 5d
Durrant C, Ruscher K, Sheppard O, Coleman M, Ozen I. Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling. Cell Death Dis. 2020;11:98 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1c
Wimmer R, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, et al. Human blood vessel organoids as a model of diabetic vasculopathy. Nature. 2019;565:505-510 pubmed 出版商
  • 免疫细胞化学; 人类; 1:300; 图 2c
Karow M, Camp J, Falk S, Gerber T, Pataskar A, Gac Santel M, et al. Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program. Nat Neurosci. 2018;21:932-940 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 s2b
Chung M, Bujnis M, Barkauskas C, Kobayashi Y, Hogan B. Niche-mediated BMP/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation. Development. 2018;145: pubmed 出版商
  • 其他; 人类; 图 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 4b
Strell C, Norberg K, Mezheyeuski A, Schnittert J, Kuninty P, Moro C, et al. Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC. Br J Cancer. 2017;117:65-77 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 8b
Gautam J, Zhang X, Yao Y. The role of pericytic laminin in blood brain barrier integrity maintenance. Sci Rep. 2016;6:36450 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 表 1
  • 免疫印迹; 人类; 1:1000; 表 1
Jansson D, Scotter E, Rustenhoven J, Coppieters N, Smyth L, Oldfield R, et al. Interferon-? blocks signalling through PDGFR? in human brain pericytes. J Neuroinflammation. 2016;13:249 pubmed
  • 免疫印迹; 人类; 1:1000; 图 2
Chen P, Qin L, Li G, Tellides G, Simons M. Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGF?)-dependent smooth muscle cell phenotype modulation. Sci Rep. 2016;6:33407 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3f
Jiang M, Qiu J, Zhang L, Lu D, Long M, Chen L, et al. Changes in tension regulates proliferation and migration of fibroblasts by remodeling expression of ECM proteins. Exp Ther Med. 2016;12:1542-1550 pubmed
  • 免疫细胞化学; 人类; 1:200; 图 1
Sobrino A, Phan D, Datta R, Wang X, Hachey S, Romero López M, et al. 3D microtumors in vitro supported by perfused vascular networks. Sci Rep. 2016;6:31589 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 8
  • 免疫印迹; 小鼠; 图 8
  • 免疫组化-石蜡切片; 人类; 图 7
  • 免疫印迹; 人类; 图 7
Kobayashi K, Araya J, Minagawa S, Hara H, Saito N, Kadota T, et al. Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis. J Immunol. 2016;197:504-16 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 7
Yao Y, Norris E, Mason C, Strickland S. Laminin regulates PDGFR?(+) cell stemness and muscle development. Nat Commun. 2016;7:11415 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2g
Rorsman C, Tsioumpekou M, Heldin C, Lennartsson J. The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling. J Biol Chem. 2016;291:11608-18 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 se1a
  • 免疫印迹; 小鼠; 图 1f
Ishibashi T, Yaguchi A, Terada K, Ueno Yokohata H, Tomita O, Iijima K, et al. Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB exhibits high sensitivity to tyrosine kinase inhibitors in murine cells. Exp Hematol. 2016;44:177-88.e5 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Rodda L, Bannard O, Ludewig B, Nagasawa T, Cyster J. Phenotypic and Morphological Properties of Germinal Center Dark Zone Cxcl12-Expressing Reticular Cells. J Immunol. 2015;195:4781-91 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 s1n
  • 流式细胞仪; 小鼠; 图 s1t
Hurtado R, Zewdu R, Mtui J, Liang C, Aho R, Kurylo C, et al. Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning. Development. 2015;142:2653-64 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 4
Koos B, Cane G, Grannas K, Löf L, ArngÃ¥rden L, Heldin J, et al. Proximity-dependent initiation of hybridization chain reaction. Nat Commun. 2015;6:7294 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:200
Matsushita T, Lankford K, Arroyo E, Sasaki M, Neyazi M, Radtke C, et al. Diffuse and persistent blood-spinal cord barrier disruption after contusive spinal cord injury rapidly recovers following intravenous infusion of bone marrow mesenchymal stem cells. Exp Neurol. 2015;267:152-64 pubmed 出版商
  • 免疫印迹; 人类
Jayaprakash P, Dong H, Zou M, Bhatia A, O Brien K, Chen M, et al. Hsp90α and Hsp90β together operate a hypoxia and nutrient paucity stress-response mechanism during wound healing. J Cell Sci. 2015;128:1475-80 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1a
Tomasovic A, Kurrle N, Sürün D, Heidler J, Husnjak K, Poser I, et al. Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions. J Biol Chem. 2015;290:9738-52 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 表 1
Crncec I, Pathria P, Svinka J, Eferl R. Induction of colorectal cancer in mice and histomorphometric evaluation of tumors. Methods Mol Biol. 2015;1267:145-64 pubmed 出版商
  • 免疫组化; 人类; 1:50
Swager S, Delfín D, Rastogi N, Wang H, Canan B, Fedorov V, et al. Claudin-5 levels are reduced from multiple cell types in human failing hearts and are associated with mislocalization of ephrin-B1. Cardiovasc Pathol. 2015;24:160-167 pubmed 出版商
  • 免疫组化; 小鼠; 图 3
Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, et al. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. J Exp Med. 2014;211:2249-63 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s6
Lu H, Clauser K, Tam W, Fröse J, Ye X, Eaton E, et al. A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages. Nat Cell Biol. 2014;16:1105-17 pubmed 出版商
  • 流式细胞仪; 人类; 1:200
  • 免疫细胞化学; 人类; 1:200
Karow M, Schichor C, Beckervordersandforth R, Berninger B. Lineage-reprogramming of pericyte-derived cells of the adult human brain into induced neurons. J Vis Exp. 2014;: pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:100
  • 免疫印迹; 大鼠
Buschmann I, Hackbusch D, Gatzke N, Dülsner A, Trappiel M, Dagnell M, et al. Inhibition of protein tyrosine phosphatases enhances cerebral collateral growth in rats. J Mol Med (Berl). 2014;92:983-94 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 2
Yao Y, Chen Z, Norris E, Strickland S. Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity. Nat Commun. 2014;5:3413 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:50
Fretz J, Nelson T, Velazquez H, Xi Y, Moeckel G, Horowitz M. Early B-cell factor 1 is an essential transcription factor for postnatal glomerular maturation. Kidney Int. 2014;85:1091-102 pubmed 出版商
Shibahara T, Ago T, Nakamura K, Tachibana M, Yoshikawa Y, Komori M, et al. Pericyte-Mediated Tissue Repair through PDGFRβ Promotes Peri-Infarct Astrogliosis, Oligodendrogenesis, and Functional Recovery after Acute Ischemic Stroke. Eneuro. 2020;7: pubmed 出版商
Xian X, Ding Y, Dieckmann M, Zhou L, Plattner F, Liu M, et al. LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis. elife. 2017;6: pubmed 出版商
Wei Y, Kim T, Peng D, Duan D, Gibbons D, Yamauchi M, et al. Fibroblast-specific inhibition of TGF-?1 signaling attenuates lung and tumor fibrosis. J Clin Invest. 2017;127:3675-3688 pubmed 出版商
Fischer A, Mühlhäuser W, Warscheid B, Radziwill G. Membrane localization of acetylated CNK1 mediates a positive feedback on RAF/ERK signaling. Sci Adv. 2017;3:e1700475 pubmed 出版商
Andreone B, Chow B, Tata A, Lacoste B, Ben Zvi A, Bullock K, et al. Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis. Neuron. 2017;94:581-594.e5 pubmed 出版商
Hijmans R, Rasmussen D, Yazdani S, Navis G, van Goor H, Karsdal M, et al. Urinary collagen degradation products as early markers of progressive renal fibrosis. J Transl Med. 2017;15:63 pubmed 出版商
Reynolds L, D Amico G, Lechertier T, Papachristodoulou A, Muñoz Félix J, De Arcangelis A, et al. Dual role of pericyte ?6?1-integrin in tumour blood vessels. J Cell Sci. 2017;130:1583-1595 pubmed 出版商
Nordby Y, Richardsen E, Rakaee M, Ness N, Donnem T, Patel H, et al. High expression of PDGFR-β in prostate cancer stroma is independently associated with clinical and biochemical prostate cancer recurrence. Sci Rep. 2017;7:43378 pubmed 出版商
Frödin M, Mezheyeuski A, Corvigno S, Harmenberg U, Sandstrom P, Egevad L, et al. Perivascular PDGFR-? is an independent marker for prognosis in renal cell carcinoma. Br J Cancer. 2017;116:195-201 pubmed 出版商
Mochida S, Hida Y, Tanifuji S, Hagiwara A, Hamada S, Abe M, et al. SAD-B Phosphorylation of CAST Controls Active Zone Vesicle Recycling for Synaptic Depression. Cell Rep. 2016;16:2901-2913 pubmed 出版商
Poosti F, Bansal R, Yazdani S, Prakash J, Beljaars L, van den Born J, et al. Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice. Oncotarget. 2016;7:54240-54252 pubmed 出版商
Yu Q, Song W, Wang D, Zeng Y. Identification of blood vascular endothelial stem cells by the expression of protein C receptor. Cell Res. 2016;26:1079-1098 pubmed 出版商
Corvigno S, Wisman G, Mezheyeuski A, van der Zee A, Nijman H, Avall Lundqvist E, et al. Markers of fibroblast-rich tumor stroma and perivascular cells in serous ovarian cancer: Inter- and intra-patient heterogeneity and impact on survival. Oncotarget. 2016;7:18573-84 pubmed 出版商
Friedman A, Amzallag A, Pruteanu Malinici I, Baniya S, Cooper Z, Piris A, et al. Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment. PLoS ONE. 2015;10:e0140310 pubmed 出版商
Peyre M, Salaud C, Clermont Taranchon E, Niwa Kawakita M, Goutagny S, Mawrin C, et al. PDGF activation in PGDS-positive arachnoid cells induces meningioma formation in mice promoting tumor progression in combination with Nf2 and Cdkn2ab loss. Oncotarget. 2015;6:32713-22 pubmed 出版商
Ohsaka A, Hirota Komatsu S, Araki M, Komatsu N. Platelet-derived growth factor receptors form complexes with neuropilin-1 during megakaryocytic differentiation of thrombopoietin-dependent UT-7/TPO cells. Biochem Biophys Res Commun. 2015;459:443-9 pubmed 出版商
Xi Y, Chen M, Liu X, Lu Z, Ding Y, Li D. CP-673451, a platelet-derived growth-factor receptor inhibitor, suppresses lung cancer cell proliferation and migration. Onco Targets Ther. 2014;7:1215-21 pubmed 出版商
Sánchez Contreras M, Baker M, Finch N, Nicholson A, Wojtas A, Wszolek Z, et al. Genetic screening and functional characterization of PDGFRB mutations associated with basal ganglia calcification of unknown etiology. Hum Mutat. 2014;35:964-71 pubmed 出版商
Berghoff A, Birner P, Streubel B, Kenner L, Preusser M. ALK gene aberrations and the JUN/JUNB/PDGFR axis in metastatic NSCLC. APMIS. 2014;122:867-72 pubmed 出版商
Nakamura I, Zakharia K, Banini B, Mikhail D, Kim T, Yang J, et al. Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling. PLoS ONE. 2014;9:e92273 pubmed 出版商
Hagiwara K, Obayashi T, Sakayori N, Yamanishi E, Hayashi R, Osumi N, et al. Molecular and cellular features of murine craniofacial and trunk neural crest cells as stem cell-like cells. PLoS ONE. 2014;9:e84072 pubmed 出版商
Nair D, Miller K, Lourenssen S, Blennerhassett M. Inflammatory cytokines promote growth of intestinal smooth muscle cells by induced expression of PDGF-R?. J Cell Mol Med. 2014;18:444-54 pubmed 出版商
Mederacke I, Hsu C, Troeger J, Huebener P, Mu X, Dapito D, et al. Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology. Nat Commun. 2013;4:2823 pubmed 出版商
Craig J, Mikhailenko I, Noyes N, Migliorini M, Strickland D. The LDL receptor-related protein 1 (LRP1) regulates the PDGF signaling pathway by binding the protein phosphatase SHP-2 and modulating SHP-2- mediated PDGF signaling events. PLoS ONE. 2013;8:e70432 pubmed 出版商
Hua Y, Dolence J, Ramanan S, Ren J, Nair S. Bisdemethoxycurcumin inhibits PDGF-induced vascular smooth muscle cell motility and proliferation. Mol Nutr Food Res. 2013;57:1611-8 pubmed 出版商
Helmy K, Halliday J, Fomchenko E, Setty M, Pitter K, Hafemeister C, et al. Identification of global alteration of translational regulation in glioma in vivo. PLoS ONE. 2012;7:e46965 pubmed 出版商
Wehler T, Hamdi S, Maderer A, Graf C, Gockel I, Schmidtmann I, et al. Single-agent therapy with sorafenib or 5-FU is equally effective in human colorectal cancer xenograft--no benefit of combination therapy. Int J Colorectal Dis. 2013;28:385-98 pubmed 出版商
Chen J, Ortmeier S, Savinova O, Nareddy V, Beyer A, Wang D, et al. Thyroid hormone induces sprouting angiogenesis in adult heart of hypothyroid mice through the PDGF-Akt pathway. J Cell Mol Med. 2012;16:2726-35 pubmed 出版商
Weibrecht I, Grundberg I, Nilsson M, Söderberg O. Simultaneous visualization of both signaling cascade activity and end-point gene expression in single cells. PLoS ONE. 2011;6:e20148 pubmed 出版商
Nazarenko I, Hedrén A, Sjodin H, Orrego A, Andrae J, Afink G, et al. Brain abnormalities and glioma-like lesions in mice overexpressing the long isoform of PDGF-A in astrocytic cells. PLoS ONE. 2011;6:e18303 pubmed 出版商
Hägglöf C, Hammarsten P, Josefsson A, Stattin P, Paulsson J, Bergh A, et al. Stromal PDGFRbeta expression in prostate tumors and non-malignant prostate tissue predicts prostate cancer survival. PLoS ONE. 2010;5:e10747 pubmed 出版商
产品信息
SKU号 :
3169P
产品名称 :
PDGF Receptor β (28E1) Rabbit mAb
规格 :
40微升
Price-(USD) :
123美元
物种x :
H, M, R
应用 :
免疫荧光(免疫细胞化学)
产品种类 :
RTK
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
190
宿主 :
靶标 :
PDGFR-b
最初蛋白 :
血小板衍生的生长因子受体b
别名 :
Beta-type platelet-derived growth factor receptor,CD140 antigen-like family member B,CD140B,JTK12,PDGF-R-beta,PDGFR,PDGFR1,PDGFRB,PGFRB,platelet-derived growth factor receptor, beta polypeptide
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。