产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
丙酮酸脱氢酶(C54G1)兔单克隆抗体
目录 :
3205
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
C54G1
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片, 免疫印迹基因敲除验证
文章摘录数: 20
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 2a, 3b
Siu M, Jiang Y, Wang J, Leung T, Ngu S, Cheung A, et al. PDK1 promotes ovarian cancer metastasis by modulating tumor-mesothelial adhesion, invasion, and angiogenesis via α5β1 integrin and JNK/IL-8 signaling. Oncogenesis. 2020;9:24 pubmed 出版商
  • 免疫印迹; 人类; 图 3f
Zhang W, Wang G, Xu Z, Tu H, Hu F, Dai J, et al. Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS. Cell. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 图 5f
Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, et al. Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity. Sci Rep. 2017;7:46344 pubmed 出版商
  • 免疫印迹; 人类; 图 5e
Møller A, Kampmann U, Hedegaard J, Thorsen K, Nordentoft I, Vendelbo M, et al. Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes. Sci Rep. 2017;7:43775 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 2c
  • 免疫组化-石蜡切片; 人类; 图 6a
Zhong Y, Li X, Ji Y, Li X, Li Y, Yu D, et al. Pyruvate dehydrogenase expression is negatively associated with cell stemness and worse clinical outcome in prostate cancers. Oncotarget. 2017;8:13344-13356 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3g
Zeng Q, Chen J, Li Y, Werle K, Zhao R, Quan C, et al. LKB1 inhibits HPV-associated cancer progression by targeting cellular metabolism. Oncogene. 2017;36:1245-1255 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Christensen B, Nellemann B, Jørgensen J, Pedersen S, Jessen N. Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo. Lipids Health Dis. 2016;15:160 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 3a
Li Y, Li X, Li X, Zhong Y, Ji Y, Yu D, et al. PDHA1 gene knockout in prostate cancer cells results in metabolic reprogramming towards greater glutamine dependence. Oncotarget. 2016;7:53837-53852 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Ma T, Fan B, Zhang C, Zhao H, Han C, Gao C, et al. Metabonomics applied in exploring the antitumour mechanism of physapubenolide on hepatocellular carcinoma cells by targeting glycolysis through the Akt-p53 pathway. Sci Rep. 2016;6:29926 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 表 1
Martins A, Sá R, Monteiro M, Barros A, Sousa M, Carvalho R, et al. Ghrelin acts as energy status sensor of male reproduction by modulating Sertoli cells glycolytic metabolism and mitochondrial bioenergetics. Mol Cell Endocrinol. 2016;434:199-209 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1c
Gray L, Rauckhorst A, Taylor E. A Method for Multiplexed Measurement of Mitochondrial Pyruvate Carrier Activity. J Biol Chem. 2016;291:7409-17 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 8
Lesmana R, Sinha R, Singh B, Zhou J, Ohba K, Wu Y, et al. Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. Endocrinology. 2016;157:23-38 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4b
Loureiro R, Magalhães Novais S, Mesquita K, Baldeiras I, Sousa I, Tavares L, et al. Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells. Oncotarget. 2015;6:17081-96 pubmed
  • 免疫印迹; 大鼠; 1:10000
Wang W, Visavadiya N, Pandya J, Nelson P, Sullivan P, Springer J. Mitochondria-associated microRNAs in rat hippocampus following traumatic brain injury. Exp Neurol. 2015;265:84-93 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Furuya N, Ikeda S, Sato S, Soma S, Ezaki J, Oliva Trejo J, et al. PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation. Autophagy. 2014;10:631-41 pubmed 出版商
Puleston D, Buck M, Klein Geltink R, Kyle R, Caputa G, O Sullivan D, et al. Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation. Cell Metab. 2019;: pubmed 出版商
Pak H, Nam B, Lee Y, Kim Y, Roh J, Son J, et al. Human Plasmablast Migration Toward CXCL12 Requires Glucose Oxidation by Enhanced Pyruvate Dehydrogenase Activity via AKT. Front Immunol. 2018;9:1742 pubmed 出版商
Stein C, Jadiya P, Zhang X, McLendon J, Abouassaly G, Witmer N, et al. Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency. Cell Rep. 2018;23:3710-3720.e8 pubmed 出版商
Tang M, Vranas M, Krahn A, Pundlik S, Trempe J, Fon E. Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation. Nat Commun. 2017;8:14697 pubmed 出版商
Zhang C, Lin M, Wu R, Wang X, Yang B, Levine A, et al. Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect. Proc Natl Acad Sci U S A. 2011;108:16259-64 pubmed 出版商
产品信息
SKU号 :
3205S
产品名称 :
丙酮酸脱氢酶(C54G1)兔单克隆抗体
规格 :
100微升
Price-(USD) :
235美元
物种x :
H, M, R, Mk
应用 :
免疫组化(石蜡)
产品种类 :
代谢
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
43
宿主 :
靶标 :
PDHA1
最初蛋白 :
PDHA1
别名 :
ODPA,PDHA,PDHA1,PDHCE1A,PDHE1-A type I,PHE1A,Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial,pyruvate dehydrogenase (lipoamide) alpha 1,pyruvate dehydrogenase E1 alpha 1,pyruvate dehydrogenase complex, E1-alpha polypeptide 1
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。