产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
TCF8/ZEB1(D80D3)兔单克隆抗体
目录 :
3396
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D80D3
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 其他
文章摘录数: 76
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 10c
Li K, Wu R, Zhou M, Tong H, Luo K. Desmosomal proteins of DSC2 and PKP1 promote cancer cells survival and metastasis by increasing cluster formation in circulatory system. Sci Adv. 2021;7:eabg7265 pubmed 出版商
  • 免疫印迹; 人类; 图 6c, 6f
Sun Z, Sun D, Feng Y, Zhang B, Sun P, Zhou B, et al. Exosomal linc-ROR mediates crosstalk between cancer cells and adipocytes to promote tumor growth in pancreatic cancer. Mol Ther Nucleic Acids. 2021;26:253-268 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6b
Kariya Y, Oyama M, Suzuki T, Kariya Y. αvβ3 Integrin induces partial EMT independent of TGF-β signaling. Commun Biol. 2021;4:490 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2g: 2h, 2i
Li M, Wu P, Yang Z, Deng S, Ni L, Zhang Y, et al. miR-193a-5p promotes pancreatic cancer cell metastasis through SRSF6-mediated alternative splicing of OGDHL and ECM1. Am J Cancer Res. 2020;10:38-59 pubmed
  • 免疫印迹; 人类; 图 5a
Chen X, Xiong X, Cui D, Yang F, Wei D, Li H, et al. DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals. Oncogene. 2020;39:1557-1571 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4f
Tan P, Xu Y, Du Y, Wu L, Guo B, Huang S, et al. SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG. Cell Death Dis. 2019;10:794 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4b, s1b
Tian M, Gong W, Guo J. Long non-coding RNA SNHG1 indicates poor prognosis and facilitates disease progression in acute myeloid leukemia. Biol Open. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Jiang S, Zhang M, Zhang Y, Zhou W, Zhu T, Ruan Q, et al. WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling. Cell Commun Signal. 2019;17:109 pubmed 出版商
  • 免疫印迹; 人类; 图 3d
Li Q, Lai Q, He C, Fang Y, Yan Q, Zhang Y, et al. RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer. J Exp Clin Cancer Res. 2019;38:334 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4c
Smestad J, Maher L. Master regulator analysis of paragangliomas carrying SDHx, VHL, or MAML3 genetic alterations. BMC Cancer. 2019;19:619 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Adams C, Htwe H, Marsh T, Wang A, Montoya M, Subbaraj L, et al. Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 s2a
Sonego M, Pellarin I, Costa A, Vinciguerra G, Coan M, Kraut A, et al. USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability. Sci Adv. 2019;5:eaav3235 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Vl kov K, Vachtenheim J, R da J, Hor k P, Ondru ov L. Inducibly decreased MITF levels do not affect proliferation and phenotype switching but reduce differentiation of melanoma cells. J Cell Mol Med. 2018;22:2240-2251 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s6i
Wang J, Ye Q, Cao Y, Guo Y, Huang X, Mi W, et al. Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1. Nat Commun. 2017;8:2207 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7j
Caino M, Seo J, Wang Y, Rivadeneira D, Gabrilovich D, Kim E, et al. Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer. J Clin Invest. 2017;127:3755-3769 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 ex7b
Viswanathan V, Ryan M, Dhruv H, Gill S, Eichhoff O, Seashore Ludlow B, et al. Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway. Nature. 2017;547:453-457 pubmed 出版商
  • 免疫印迹; 人类; 图 2e
Hiramoto H, Muramatsu T, Ichikawa D, Tanimoto K, Yasukawa S, Otsuji E, et al. miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer. Sci Rep. 2017;7:4002 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Samuel W, Jaworski C, Postnikova O, Kutty R, Duncan T, Tan L, et al. Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. Mol Vis. 2017;23:60-89 pubmed
  • 免疫细胞化学; 人类; 1:100; 图 3b
Keckesova Z, Donaher J, De Cock J, Freinkman E, Lingrell S, Bachovchin D, et al. LACTB is a tumour suppressor that modulates lipid metabolism and cell state. Nature. 2017;543:681-686 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6d
Li X, Liu W, Chen X, Wang Y, Shi D, Zhang H, et al. Overexpression of TMPRSS4 promotes tumor proliferation and aggressiveness in breast cancer. Int J Mol Med. 2017;39:927-935 pubmed 出版商
  • 免疫印迹; 人类
Zhai S, Liu C, Zhang L, Zhu J, Guo J, Zhang J, et al. PLCE1 Promotes Esophageal Cancer Cell Progression by Maintaining the Transcriptional Activity of Snail. Neoplasia. 2017;19:154-164 pubmed 出版商
  • 免疫印迹; 人类; 图 7d
Fletcher C, Godfrey J, Shibakawa A, Bushell M, Bevan C. A novel role for GSK3? as a modulator of Drosha microprocessor activity and MicroRNA biogenesis. Nucleic Acids Res. 2016;: pubmed
  • 免疫组化; 小鼠; 图 8l
Zhang Q, Liu S, Parajuli K, Zhang W, Zhang K, Mo Z, et al. Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition. Oncogene. 2017;36:687-699 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s3b
Pattabiraman D, Bierie B, Kober K, Thiru P, Krall J, Zill C, et al. Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. Science. 2016;351:aad3680 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Chung V, Tan T, Tan M, Wong M, Kuay K, Yang Z, et al. GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification. Sci Rep. 2016;6:19943 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Haraguchi T, Kondo M, Uchikawa R, Kobayashi K, Hiramatsu H, Kobayashi K, et al. Dynamics and plasticity of the epithelial to mesenchymal transition induced by miR-200 family inhibition. Sci Rep. 2016;6:21117 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2
Fazio C, Piazzi G, Vitaglione P, Fogliano V, Munarini A, Prossomariti A, et al. Inflammation increases NOTCH1 activity via MMP9 and is counteracted by Eicosapentaenoic Acid-free fatty acid in colon cancer cells. Sci Rep. 2016;6:20670 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Wang F, Feng Y, Li P, Wang K, Feng L, Liu Y, et al. RASSF10 is an epigenetically inactivated tumor suppressor and independent prognostic factor in hepatocellular carcinoma. Oncotarget. 2016;7:4279-97 pubmed 出版商
  • 免疫印迹; 人类; 图 8b
Chen C, Zhu C, Huang J, Zhao X, Deng R, Zhang H, et al. SUMOylation of TARBP2 regulates miRNA/siRNA efficiency. Nat Commun. 2015;6:8899 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1d
Nagaoka K, Fujii K, Zhang H, Usuda K, Watanabe G, Ivshina M, et al. CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis. Oncogene. 2016;35:2893-901 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Yokdang N, Hatakeyama J, Wald J, Simion C, Tellez J, Chang D, et al. LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Oncogene. 2016;35:2932-47 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Zhu C, Chen C, Huang J, Zhang H, Zhao X, Deng R, et al. SUMOylation at K707 of DGCR8 controls direct function of primary microRNA. Nucleic Acids Res. 2015;43:7945-60 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2
Zucha M, Wu A, Lee W, Wang L, Lin W, Yuan C, et al. Bruton's tyrosine kinase (Btk) inhibitor ibrutinib suppresses stem-like traits in ovarian cancer. Oncotarget. 2015;6:13255-68 pubmed
  • 其他; 人类; 图 4a, 4d
Yamada A, Aki T, Unuma K, Funakoshi T, Uemura K. Paraquat induces epithelial-mesenchymal transition-like cellular response resulting in fibrogenesis and the prevention of apoptosis in human pulmonary epithelial cells. PLoS ONE. 2015;10:e0120192 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Lin Y, Yang Z, Xu A, Dong P, Huang Y, Liu H, et al. PIK3R1 negatively regulates the epithelial-mesenchymal transition and stem-like phenotype of renal cancer cells through the AKT/GSK3β/CTNNB1 signaling pathway. Sci Rep. 2015;5:8997 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
  • 免疫印迹; 小鼠
Knezevic J, Pfefferle A, Petrovic I, Greene S, Perou C, Rosen J. Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential. Oncogene. 2015;34:5997-6006 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Cheng Y, Chen P, Chiang H, Suen C, Hwang M, Lin T, et al. Candidate tumor suppressor B-cell translocation gene 3 impedes neoplastic progression by suppression of AKT. Cell Death Dis. 2015;6:e1584 pubmed 出版商
  • 免疫细胞化学; 人类
Tange S, Oktyabri D, Terashima M, Ishimura A, Suzuki T. JARID2 is involved in transforming growth factor-beta-induced epithelial-mesenchymal transition of lung and colon cancer cell lines. PLoS ONE. 2014;9:e115684 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Gong X, Yi J, Carmon K, Crumbley C, Xiong W, Thomas A, et al. Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness. Oncogene. 2015;34:4692-701 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Xu M, Zhu C, Zhao X, Chen C, Zhang H, Yuan H, et al. Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors. Oncotarget. 2015;6:979-94 pubmed
  • 免疫印迹; 人类
Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, et al. Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 2014;26:222-34 pubmed 出版商
  • 免疫印迹; 人类
Subramani R, Lopez Valdez R, Arumugam A, Nandy S, Boopalan T, Lakshmanaswamy R. Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. PLoS ONE. 2014;9:e97016 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2e
Feuerborn A, Mathow D, Srivastava P, Gretz N, Grone H. Basonuclin-1 modulates epithelial plasticity and TGF-?1-induced loss of epithelial cell integrity. Oncogene. 2015;34:1185-95 pubmed 出版商
  • 免疫印迹; 人类
Wu K, Chen K, Wang C, Jiao X, Wang L, Zhou J, et al. Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation. Cancer Res. 2014;74:829-39 pubmed 出版商
  • 免疫印迹; 人类
Harazono Y, Muramatsu T, Endo H, Uzawa N, Kawano T, Harada K, et al. miR-655 Is an EMT-suppressive microRNA targeting ZEB1 and TGFBR2. PLoS ONE. 2013;8:e62757 pubmed 出版商
Monteleone L, Speciale A, Valenti G, Traverso N, Ravera S, Garbarino O, et al. PKCα Inhibition as a Strategy to Sensitize Neuroblastoma Stem Cells to Etoposide by Stimulating Ferroptosis. Antioxidants (Basel). 2021;10: pubmed 出版商
Deng W, Fernandez A, McLaughlin S, Klinke D. WNT1-inducible signaling pathway protein 1 (WISP1/CCN4) stimulates melanoma invasion and metastasis by promoting the epithelial-mesenchymal transition. J Biol Chem. 2019;294:5261-5280 pubmed 出版商
Sanawar R, Mohan Dan V, Santhoshkumar T, Kumar R, Pillai M. Estrogen receptor-α regulation of microRNA-590 targets FAM171A1-a modifier of breast cancer invasiveness. Oncogenesis. 2019;8:5 pubmed 出版商
Roh V, Abramowski P, Hiou Feige A, Cornils K, Rivals J, Zougman A, et al. Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma. Cell Rep. 2018;25:2208-2222.e7 pubmed 出版商
Ooki A, Begum A, Marchionni L, Vandenbussche C, Mao S, Kates M, et al. Arsenic promotes the COX2/PGE2-SOX2 axis to increase the malignant stemness properties of urothelial cells. Int J Cancer. 2018;143:113-126 pubmed 出版商
Li Y, Liang Y, Sang Y, Song X, Zhang H, Liu Y, et al. MiR-770 suppresses the chemo-resistance and metastasis of triple negative breast cancer via direct targeting of STMN1. Cell Death Dis. 2018;9:14 pubmed 出版商
Song K, Niederst M, Lochmann T, Hata A, Kitai H, Ham J, et al. Epithelial-to-Mesenchymal Transition Antagonizes Response to Targeted Therapies in Lung Cancer by Suppressing BIM. Clin Cancer Res. 2018;24:197-208 pubmed 出版商
Kessler T, Wobst J, Wolf B, Eckhold J, Vilne B, Hollstein R, et al. Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus. Circulation. 2017;136:476-489 pubmed 出版商
Smigiel J, Parameswaran N, Jackson M. Potent EMT and CSC Phenotypes Are Induced By Oncostatin-M in Pancreatic Cancer. Mol Cancer Res. 2017;15:478-488 pubmed 出版商
Lee N, Lee J, Kim W, Yun S, Youn Y, Park C, et al. Promoter methylation of PCDH10 by HOTAIR regulates the progression of gastrointestinal stromal tumors. Oncotarget. 2016;7:75307-75318 pubmed 出版商
Zhang L, Zhang W, Li Y, Alvarez A, Li Z, Wang Y, et al. SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans. Oncogene. 2016;35:5641-5652 pubmed 出版商
Park S, Korm S, Chung H, Choi S, Jang J, Cho S, et al. RAP80 regulates epithelial-mesenchymal transition related with metastasis and malignancy of cancer. Cancer Sci. 2016;107:267-73 pubmed 出版商
Sun K, Zeng T, Huang D, Liu Z, Huang S, Liu J, et al. MicroRNA-431 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the ZEB1-mediated epithelial-mensenchymal transition. FEBS Open Bio. 2015;5:900-7 pubmed 出版商
Shah P, Beverly L. Regulation of VCP/p97 demonstrates the critical balance between cell death and epithelial-mesenchymal transition (EMT) downstream of ER stress. Oncotarget. 2015;6:17725-37 pubmed
Han Y, Ye J, Wu D, Wu P, Chen Z, Chen J, et al. LEIGC long non-coding RNA acts as a tumor suppressor in gastric carcinoma by inhibiting the epithelial-to-mesenchymal transition. BMC Cancer. 2014;14:932 pubmed 出版商
Tseng C, Hong Y, Chang H, Yu T, Hung T, Hou M, et al. Brefeldin A reduces anchorage-independent survival, cancer stem cell potential and migration of MDA-MB-231 human breast cancer cells. Molecules. 2014;19:17464-77 pubmed 出版商
Subramani R, Lopez Valdez R, Salcido A, Boopalan T, Arumugam A, Nandy S, et al. Growth hormone receptor inhibition decreases the growth and metastasis of pancreatic ductal adenocarcinoma. Exp Mol Med. 2014;46:e117 pubmed 出版商
Shah P, Lockwood W, Saurabh K, Kurlawala Z, Shannon S, Waigel S, et al. Ubiquilin1 represses migration and epithelial-to-mesenchymal transition of human non-small cell lung cancer cells. Oncogene. 2015;34:1709-17 pubmed 出版商
Marín Aguilera M, Codony Servat J, Reig O, Lozano J, Fernandez P, Pereira M, et al. Epithelial-to-mesenchymal transition mediates docetaxel resistance and high risk of relapse in prostate cancer. Mol Cancer Ther. 2014;13:1270-84 pubmed 出版商
Patel K, Kollory A, Takashima A, Sarkar S, Faller D, Ghosh S. MicroRNA let-7 downregulates STAT3 phosphorylation in pancreatic cancer cells by increasing SOCS3 expression. Cancer Lett. 2014;347:54-64 pubmed 出版商
Hu Y, Li S, Yang M, Yan C, Fan D, Zhou Y, et al. Sorcin silencing inhibits epithelial-to-mesenchymal transition and suppresses breast cancer metastasis in vivo. Breast Cancer Res Treat. 2014;143:287-99 pubmed 出版商
Kim J, Wu L, Zhao J, Jin H, Yu J. TMPRSS2-ERG gene fusions induce prostate tumorigenesis by modulating microRNA miR-200c. Oncogene. 2014;33:5183-92 pubmed 出版商
Ding W, Dang H, You H, Steinway S, Takahashi Y, Wang H, et al. miR-200b restoration and DNA methyltransferase inhibitor block lung metastasis of mesenchymal-phenotype hepatocellular carcinoma. Oncogenesis. 2012;1:e15 pubmed 出版商
Morris L, Kaufman A, Gong Y, Ramaswami D, Walsh L, Turcan S, et al. Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation. Nat Genet. 2013;45:253-61 pubmed 出版商
Liang Y, Wang Q, Zhou C, Yin Q, He M, Yu X, et al. MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer. Carcinogenesis. 2013;34:713-22 pubmed 出版商
Yokobori T, Suzuki S, Tanaka N, Inose T, Sohda M, Sano A, et al. MiR-150 is associated with poor prognosis in esophageal squamous cell carcinoma via targeting the EMT inducer ZEB1. Cancer Sci. 2013;104:48-54 pubmed 出版商
Ono H, Imoto I, Kozaki K, Tsuda H, Matsui T, Kurasawa Y, et al. SIX1 promotes epithelial-mesenchymal transition in colorectal cancer through ZEB1 activation. Oncogene. 2012;31:4923-34 pubmed 出版商
Byles V, Zhu L, Lovaas J, Chmilewski L, Wang J, Faller D, et al. SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis. Oncogene. 2012;31:4619-29 pubmed 出版商
Sun Y, Wang B, Leong K, Yue P, Li L, Jhunjhunwala S, et al. Androgen deprivation causes epithelial-mesenchymal transition in the prostate: implications for androgen-deprivation therapy. Cancer Res. 2012;72:527-36 pubmed 出版商
Kurasawa Y, Kozaki K, Pimkhaokham A, Muramatsu T, Ono H, Ishihara T, et al. Stabilization of phenotypic plasticity through mesenchymal-specific DNA hypermethylation in cancer cells. Oncogene. 2012;31:1963-74 pubmed 出版商
Chang C, Chao C, Xia W, Yang J, Xiong Y, Li C, et al. p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol. 2011;13:317-23 pubmed 出版商
产品信息
SKU号 :
3396S
产品名称 :
TCF8/ZEB1(D80D3)兔单克隆抗体
规格 :
100微升
Price-(USD) :
235美元
物种x :
H,(M, R)
应用 :
免疫沉淀
产品种类 :
发育生物学
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
200
宿主 :
靶标 :
TCF8
最初蛋白 :
TCF8
别名 :
AREB6,BZP,DELTAEF1,FECD6,MGC133261,NIL-2-A zinc finger protein,NIL2A,Negative regulator of IL2,TCF-8,TCF8,Transcription factor 8,ZEB1,ZFHEP,ZFHX1A,Zinc finger E-box-binding homeobox 1,delta-crystallin enhancer binding factor 1,transcription factor 8 (represses interleukin 2 expression),zinc finger E-box binding homeobox 1,zinc finger homeodomain enhancer-binding protein
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。