产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Hydroxy-HIF-1α (Pro564) (D43B5) XP® Rabbit mAb
目录 :
3434
克隆性 :
单克隆
宿主 :
共轭标签 :
nonconjugated
克隆名称 :
D43B5
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 免疫组化-冰冻切片
文章摘录数: 19
出版应用/物种/样品/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 图 s3g
Ho L, van Dijk M, Chye S, Messerschmidt D, Chng S, Ong S, et al. ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice. Science. 2017;357:707-713 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 7E
Miles A, Burr S, Grice G, Nathan J. The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1? prolyl hydroxylation by regulating cellular iron levels. elife. 2017;6: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Karuppagounder S, Alim I, Khim S, Bourassa M, Sleiman S, John R, et al. Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Sci Transl Med. 2016;8:328ra29 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 s1
Kim Y, Nam H, Lee J, Park D, Kim C, Yu Y, et al. Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis. Nat Commun. 2016;7:10347 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4g
Lin A, Li C, Xing Z, Hu Q, Liang K, Han L, et al. The LINK-A lncRNA activates normoxic HIF1? signalling in triple-negative breast cancer. Nat Cell Biol. 2016;18:213-24 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 3
Chan M, Atasoylu O, Hodson E, Tumber A, Leung I, Chowdhury R, et al. Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain. PLoS ONE. 2015;10:e0132004 pubmed 出版商
  • 免疫沉淀; 人类; 图 8
Kumar P, Gullberg U, Olsson I, Ajore R. Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1. PLoS ONE. 2015;10:e0123725 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Sun Y, George J, Rocha S. Dose-dependent effects of allopurinol on human foreskin fibroblast cells and human umbilical vein endothelial cells under hypoxia. PLoS ONE. 2015;10:e0123649 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Ma B, Chen Y, Chen L, Cheng H, Mu C, Li J, et al. Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase. Nat Cell Biol. 2015;17:95-103 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Zheng X, Zhai B, Koivunen P, Shin S, Lu G, Liu J, et al. Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase. Genes Dev. 2014;28:1429-44 pubmed 出版商
Koukourakis M, Giatromanolaki A, Zois C, Kalamida D, Pouliliou S, Karagounis I, et al. Normal tissue radioprotection by amifostine via Warburg-type effects. Sci Rep. 2016;6:30986 pubmed 出版商
Lee G, Won H, Lee Y, Choi J, Oh T, Jang J, et al. Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation. Sci Rep. 2016;6:18928 pubmed 出版商
Hou P, Kuo C, Cheng C, Liou J, Ann D, Chen Q. Intermediary metabolite precursor dimethyl-2-ketoglutarate stabilizes hypoxia-inducible factor-1α by inhibiting prolyl-4-hydroxylase PHD2. PLoS ONE. 2014;9:e113865 pubmed 出版商
Li B, Iglesias Pedraz J, Chen L, Yin F, Cadenas E, Reddy S, et al. Downregulation of the Werner syndrome protein induces a metabolic shift that compromises redox homeostasis and limits proliferation of cancer cells. Aging Cell. 2014;13:367-78 pubmed
Snell C, Turley H, McIntyre A, Li D, Masiero M, Schofield C, et al. Proline-hydroxylated hypoxia-inducible factor 1? (HIF-1?) upregulation in human tumours. PLoS ONE. 2014;9:e88955 pubmed 出版商
Yang Y, Li X, Wang L, Han S, Zhang Y, Pratheeshkumar P, et al. Anti-apoptotic proteins and catalase-dependent apoptosis resistance in nickel chloride-transformed human lung epithelial cells. Int J Oncol. 2013;43:936-46 pubmed 出版商
Ohara T, Noma K, Urano S, Watanabe S, Nishitani S, Tomono Y, et al. A novel synergistic effect of iron depletion on antiangiogenic cancer therapy. Int J Cancer. 2013;132:2705-13 pubmed 出版商
Tian Y, Yeoh K, Lee M, Eriksson T, Kessler B, Kramer H, et al. Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors. J Biol Chem. 2011;286:13041-51 pubmed 出版商
产品信息
SKU号 :
3434S
产品名称 :
Hydroxy-HIF-1α (Pro564) (D43B5) XP® Rabbit mAb
规格 :
100微升
Price-(USD) :
301美元
物种x :
H, (M, R, Mk, C, X, Z, Pg)
应用 :
免疫荧光(免疫细胞化学)
产品种类 :
发育生物学
运输温度 :
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
120
宿主 :
靶标 :
HIF1A (Pro564) hydroxylate
最初蛋白 :
缺氧诱导因子1A
别名 :
ARNT interacting protein,ARNT-interacting protein,BHLHE78,Basic-helix-loop-helix-PAS protein MOP1,Class E basic helix-loop-helix protein 78,HIF-1-alpha,HIF-1alpha,HIF1,HIF1-alpha,HIF1A,Hypoxia-inducible factor 1-alpha,MOP1,Member of PAS protein 1,PAS domain-containing protein 8,PASD8,hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor),hypoxia-inducible factor 1 alpha isoform I.3,hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor),member of PAS superfamily 1
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。