| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
| Zhang J, Lee Y, Dang F, Gan W, Menon A, Katon J, et al. PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. Cancer Discov. 2019;: pubmed 出版商 |
| Chan E, Shibue T, McFarland J, Gaeta B, Ghandi M, Dumont N, et al. WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature. 2019;568:551-556 pubmed 出版商 |
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商 |
- reverse phase protein lysate microarray; 人类; 图 st6
| Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed 出版商 |
| Wamsley J, Issaeva N, An H, Lu X, Donehower L, Yarbrough W. LZAP is a novel Wip1 binding partner and positive regulator of its phosphatase activity in vitro. Cell Cycle. 2017;16:213-223 pubmed 出版商 |
| Shibata E, Kiran M, Shibata Y, Singh S, Kiran S, Dutta A. Two subunits of human ORC are dispensable for DNA replication and proliferation. elife. 2016;5: pubmed 出版商 |
| Sears C, Cooney S, Chin Sinex H, Mendonca M, Turchi J. DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer. DNA Repair (Amst). 2016;40:35-46 pubmed 出版商 |
| Cekan P, Hasegawa K, Pan Y, Tubman E, Odde D, Chen J, et al. RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence. Mol Biol Cell. 2016;27:1346-57 pubmed 出版商 |
| Nassour J, Martien S, Martin N, Deruy E, Tomellini E, Malaquin N, et al. Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells. Nat Commun. 2016;7:10399 pubmed 出版商 |
| Lauková J, KozubÃk A, Hofmanová J, Nekvindová J, Sova P, Moyer M, et al. Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells. PLoS ONE. 2015;10:e0141020 pubmed 出版商 |
| Kiyonari S, Iimori M, Matsuoka K, Watanabe S, Morikawa Ichinose T, Miura D, et al. The 1,2-Diaminocyclohexane Carrier Ligand in Oxaliplatin Induces p53-Dependent Transcriptional Repression of Factors Involved in Thymidylate Biosynthesis. Mol Cancer Ther. 2015;14:2332-42 pubmed 出版商 |
| Ahn J, Kim S, Na W, Baek S, Kim J, Min K, et al. SERBP1 affects homologous recombination-mediated DNA repair by regulation of CtIP translation during S phase. Nucleic Acids Res. 2015;43:6321-33 pubmed 出版商 |
| Mehta K, Gunasekharan V, Satsuka A, Laimins L. Human papillomaviruses activate and recruit SMC1 cohesin proteins for the differentiation-dependent life cycle through association with CTCF insulators. PLoS Pathog. 2015;11:e1004763 pubmed 出版商 |
| Xia J, Chen S, Lv Y, Lu L, Hu W, Zhou Y. ZGDHu-1 induces Gâ‚‚/M phase arrest and apoptosis in Kasumi-1 cells. Mol Med Rep. 2015;11:3398-404 pubmed 出版商 |
| Gubanova E, Issaeva N, Gokturk C, Djureinovic T, Helleday T. SMG-1 suppresses CDK2 and tumor growth by regulating both the p53 and Cdc25A signaling pathways. Cell Cycle. 2013;12:3770-80 pubmed 出版商 |
| Chen Y, Kamili A, Hardy J, Groblewski G, Khanna K, Byrne J. Tumor protein D52 represents a negative regulator of ATM protein levels. Cell Cycle. 2013;12:3083-97 pubmed 出版商 |
| Tuul M, Kitao H, Iimori M, Matsuoka K, Kiyonari S, Saeki H, et al. Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance. PLoS ONE. 2013;8:e55361 pubmed 出版商 |
| Sakasai R, Sakai A, Iimori M, Kiyonari S, Matsuoka K, Kakeji Y, et al. CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication. Genes Cells. 2012;17:962-70 pubmed 出版商 |
| Fan G, Sun L, Shan P, Zhang X, Huan J, Li D, et al. Loss of KLF14 triggers centrosome amplification and tumorigenesis. Nat Commun. 2015;6:8450 pubmed 出版商 |
| Raymond A, Benhamouche S, Neaud V, Di Martino J, Javary J, Rosenbaum J. Reptin regulates DNA double strand breaks repair in human hepatocellular carcinoma. PLoS ONE. 2015;10:e0123333 pubmed 出版商 |
| Keskin N, Deniz E, Eryilmaz J, Un M, Batur T, Ersahin T, et al. PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function. Mol Cell Biol. 2015;35:1741-53 pubmed 出版商 |
| Lu K, Fang X, Feng L, Jiang Y, Zhou X, Liu X, et al. The STAT3 inhibitor WP1066 reverses the resistance of chronic lymphocytic leukemia cells to histone deacetylase inhibitors induced by interleukin-6. Cancer Lett. 2015;359:250-8 pubmed 出版商 |
| Mo J, Alam K, Kang I, Park W, Seo G, Choi S, et al. MicroRNA 196B regulates FAS-mediated apoptosis in colorectal cancer cells. Oncotarget. 2015;6:2843-55 pubmed |
| Kitagawa M, Shiozaki A, Ichikawa D, Nakashima S, Kosuga T, Konishi H, et al. Tumor necrosis factor-α-induced apoptosis of gastric cancer MKN28 cells: accelerated degradation of the inhibitor of apoptosis family members. Arch Biochem Biophys. 2015;566:43-8 pubmed 出版商 |
| Lawhorn I, Ferreira J, Wang C. Evaluation of sgRNA target sites for CRISPR-mediated repression of TP53. PLoS ONE. 2014;9:e113232 pubmed 出版商 |
| Kusama K, Yoshie M, Tamura K, Imakawa K, Tachikawa E. EPAC2-mediated calreticulin regulates LIF and COX2 expression in human endometrial glandular cells. J Mol Endocrinol. 2015;54:17-24 pubmed 出版商 |
| Chen F, Cao L, Wan H, Zhang M, Cai J, Shen L, et al. Quercetin enhances adriamycin cytotoxicity through induction of apoptosis and regulation of mitogen-activated protein kinase/extracellular signal-regulated kinase/c-Jun N-terminal kinase signaling in multidrug-resistant leukemia K562 cells. Mol Med Rep. 2015;11:341-8 pubmed 出版商 |
| Momose I, Abe H, Watanabe T, Ohba S, Yamazaki K, Dan S, et al. Antitumor effects of tyropeptin-boronic acid derivatives: New proteasome inhibitors. Cancer Sci. 2014;105:1609-15 pubmed 出版商 |
| Huang E, Wang F, Chen Y, Chen Y, Wang C, Lin I, et al. Amifostine alleviates radiation-induced lethal small bowel damage via promotion of 14-3-3σ-mediated nuclear p53 accumulation. Oncotarget. 2014;5:9756-69 pubmed |
| Hurley K, Lacey N, O Dwyer C, Bergin D, McElvaney O, O Brien M, et al. Alpha-1 antitrypsin augmentation therapy corrects accelerated neutrophil apoptosis in deficient individuals. J Immunol. 2014;193:3978-91 pubmed 出版商 |
| Huang C, Chang C, Chen C, Chuang C, Chiang C, Shu W, et al. Extremely low-frequency electromagnetic fields cause G1 phase arrest through the activation of the ATM-Chk2-p21 pathway. PLoS ONE. 2014;9:e104732 pubmed 出版商 |
| Sabirzhanov B, Zhao Z, Stoica B, Loane D, Wu J, Borroto C, et al. Downregulation of miR-23a and miR-27a following experimental traumatic brain injury induces neuronal cell death through activation of proapoptotic Bcl-2 proteins. J Neurosci. 2014;34:10055-71 pubmed 出版商 |
| Siu K, Xu Y, Swartz K, Bhattacharyya M, Gurbuxani S, Hua Y, et al. Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation. Mol Cell Biol. 2014;34:3244-58 pubmed 出版商 |
| Yuan M, Eberhart C, Kai M. RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation. Oncotarget. 2014;5:2820-6 pubmed |
| Lin X, Yi Z, Diao J, Shao M, Zhao L, Cai H, et al. ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition. J Transl Med. 2014;12:105 pubmed 出版商 |
| Villa Morales M, Cobos M, González Gugel E, Alvarez Iglesias V, Martinez B, Piris M, et al. FAS system deregulation in T-cell lymphoblastic lymphoma. Cell Death Dis. 2014;5:e1110 pubmed 出版商 |
| Hung N, Chen Y, Taha A, Olivecrona M, Boet R, Wiles A, et al. Increased paired box transcription factor 8 has a survival function in glioma. BMC Cancer. 2014;14:159 pubmed 出版商 |
| Cantarella G, Di Benedetto G, Ribatti D, Saccani Jotti G, Bernardini R. Involvement of caspase 8 and c-FLIPL in the proangiogenic effects of the tumour necrosis factor-related apoptosis-inducing ligand (TRAIL). FEBS J. 2014;281:1505-13 pubmed 出版商 |
| Li Z, Zhao C, Li Z, Zhao Y, Shan S, Shi T, et al. Reconstructed mung bean trypsin inhibitor targeting cell surface GRP78 induces apoptosis and inhibits tumor growth in colorectal cancer. Int J Biochem Cell Biol. 2014;47:68-75 pubmed 出版商 |
| Guo M, Cao Y, Wang T, Song X, Liu Z, Zhou E, et al. Baicalin inhibits Staphylococcus aureus-induced apoptosis by regulating TLR2 and TLR2-related apoptotic factors in the mouse mammary glands. Eur J Pharmacol. 2014;723:481-8 pubmed 出版商 |
| Kusama K, Yoshie M, Tamura K, Nakayama T, Nishi H, Isaka K, et al. The role of exchange protein directly activated by cyclic AMP 2-mediated calreticulin expression in the decidualization of human endometrial stromal cells. Endocrinology. 2014;155:240-8 pubmed 出版商 |
| Wang S, Huang J, Lyu H, Cai B, Yang X, Li F, et al. Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer. Breast Cancer Res. 2013;15:R101 pubmed |
| Kawashima H, Takatori H, Suzuki K, Iwata A, Yokota M, Suto A, et al. Tumor suppressor p53 inhibits systemic autoimmune diseases by inducing regulatory T cells. J Immunol. 2013;191:3614-23 pubmed 出版商 |
| Kim C, Tambe Y, Mukaisho K, Sugihara H, Isono T, Sonoda H, et al. Female-specific rectal carcinogenesis in cyclin D1b transgenic mice. Carcinogenesis. 2014;35:227-36 pubmed 出版商 |
| van Dijk M, Halpin McCormick A, Sessler T, Samali A, Szegezdi E. Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways. Cell Death Dis. 2013;4:e702 pubmed 出版商 |
| Gillissen B, Richter A, Overkamp T, Essmann F, Hemmati P, Preissner R, et al. Targeted therapy of the XIAP/proteasome pathway overcomes TRAIL-resistance in carcinoma by switching apoptosis signaling to a Bax/Bak-independent 'type I' mode. Cell Death Dis. 2013;4:e643 pubmed 出版商 |
| Sung M, Giannakakou P. BRCA1 regulates microtubule dynamics and taxane-induced apoptotic cell signaling. Oncogene. 2014;33:1418-28 pubmed 出版商 |
| Ganapathy S, Xiao S, Seo S, Lall R, Yang M, Xu T, et al. Low-dose arsenic induces chemotherapy protection via p53/NF-?B-mediated metabolic regulation. Oncogene. 2014;33:1359-66 pubmed 出版商 |
| Burgeiro A, Bento A, Gajate C, Oliveira P, Mollinedo F. Rapid human melanoma cell death induced by sanguinarine through oxidative stress. Eur J Pharmacol. 2013;705:109-18 pubmed 出版商 |
| Sistrunk C, Kim S, Wang X, Lee S, Kim Y, Macias E, et al. Skp2 deficiency inhibits chemical skin tumorigenesis independent of p27(Kip1) accumulation. Am J Pathol. 2013;182:1854-64 pubmed 出版商 |
| Gaud G, Guillemot D, Jacob Y, Favre M, Vuillier F. EVER2 protein binds TRADD to promote TNF-?-induced apoptosis. Cell Death Dis. 2013;4:e499 pubmed 出版商 |
| Wu Y, Zhang Y, Wang M, Li Q, Qu Z, Shi V, et al. Downregulation of HER3 by a novel antisense oligonucleotide, EZN-3920, improves the antitumor activity of EGFR and HER2 tyrosine kinase inhibitors in animal models. Mol Cancer Ther. 2013;12:427-37 pubmed 出版商 |
| Faccenda D, Tan C, Seraphim A, Duchen M, Campanella M. IF1 limits the apoptotic-signalling cascade by preventing mitochondrial remodelling. Cell Death Differ. 2013;20:686-97 pubmed 出版商 |
| Vyas R, Kumar R, Clermont F, Helfricht A, Kalev P, Sotiropoulou P, et al. RNF4 is required for DNA double-strand break repair in vivo. Cell Death Differ. 2013;20:490-502 pubmed 出版商 |
| Kolb R, Greer P, Cao P, Cowan K, Yan Y. ERK1/2 signaling plays an important role in topoisomerase II poison-induced G2/M checkpoint activation. PLoS ONE. 2012;7:e50281 pubmed 出版商 |
| Hao J, Jin W, Li X, Wang S, Zhang X, Fan H, et al. Inhibition of alpha interferon (IFN-?)-induced microRNA-122 negatively affects the anti-hepatitis B virus efficiency of IFN-?. J Virol. 2013;87:137-47 pubmed 出版商 |
| Termén S, Tan E, Heldin C, Moustakas A. p53 regulates epithelial-mesenchymal transition induced by transforming growth factor ?. J Cell Physiol. 2013;228:801-13 pubmed 出版商 |
| Förster A, Falcone F, Gibbs B, Preussner L, Fiebig B, Altunok H, et al. Anti-Fas/CD95 and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) differentially regulate apoptosis in normal and neoplastic human basophils. Leuk Lymphoma. 2013;54:835-42 pubmed 出版商 |
| Troncale S, Barbet A, Coulibaly L, Henry E, He B, Barillot E, et al. NormaCurve: a SuperCurve-based method that simultaneously quantifies and normalizes reverse phase protein array data. PLoS ONE. 2012;7:e38686 pubmed 出版商 |
| Miura Y, Sakurai Y, Endo T. O-GlcNAc modification affects the ATM-mediated DNA damage response. Biochim Biophys Acta. 2012;1820:1678-85 pubmed 出版商 |
| Kusio Kobialka M, Wolanin K, Podszywalow Bartnicka P, Sikora E, Skowronek K, McKenna S, et al. Increased acetylation of lysine 317/320 of p53 caused by BCR-ABL protects from cytoplasmic translocation of p53 and mitochondria-dependent apoptosis in response to DNA damage. Apoptosis. 2012;17:950-63 pubmed 出版商 |
| Paunovic V, Carter N, Thalhamer T, Blair D, Gordon B, Lacey E, et al. Immune complex-mediated co-ligation of the BCR with Fc?RIIB results in homeostatic apoptosis of B cells involving Fas signalling that is defective in the MRL/Lpr model of systemic lupus erythematosus. J Autoimmun. 2012;39:332-46 pubmed 出版商 |
| Hu C, Zhang S, Gao X, Gao X, Xu X, Lv Y, et al. Roles of Kruppel-associated Box (KRAB)-associated Co-repressor KAP1 Ser-473 Phosphorylation in DNA Damage Response. J Biol Chem. 2012;287:18937-52 pubmed 出版商 |
| Chiu S, Chen S, Huang S, Wang M, Lin S, Harn H, et al. Induction of apoptosis coupled to endoplasmic reticulum stress in human prostate cancer cells by n-butylidenephthalide. PLoS ONE. 2012;7:e33742 pubmed 出版商 |
| Wang Z, Liu M, Zhu H, Zhang W, He S, Hu C, et al. miR-106a is frequently upregulated in gastric cancer and inhibits the extrinsic apoptotic pathway by targeting FAS. Mol Carcinog. 2013;52:634-46 pubmed 出版商 |
| Estornes Y, Toscano F, Virard F, Jacquemin G, Pierrot A, Vanbervliet B, et al. dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8. Cell Death Differ. 2012;19:1482-94 pubmed 出版商 |
| Tan S, Hougardy B, Meersma G, Schaap B, de Vries E, van der Zee A, et al. Human papilloma virus 16 E6 RNA interference enhances cisplatin and death receptor-mediated apoptosis in human cervical carcinoma cells. Mol Pharmacol. 2012;81:701-9 pubmed 出版商 |
| Li J, Zhang K, Meng W, Yang Y. Tanshinone IIA in acute promyelocytic leukemia. Am J Med Sci. 2012;344:283-8 pubmed |
| Miki H, Uehara N, Kimura A, Sasaki T, Yuri T, Yoshizawa K, et al. Resveratrol induces apoptosis via ROS-triggered autophagy in human colon cancer cells. Int J Oncol. 2012;40:1020-8 pubmed 出版商 |
| Deng X, Wang S, Deng A, Liu B, Edgerton S, Lind S, et al. Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers. Cell Cycle. 2012;11:367-76 pubmed 出版商 |
| Wenzel M, Wunderlich M, Besch R, Poeck H, Willms S, Schwantes A, et al. Cytosolic DNA triggers mitochondrial apoptosis via DNA damage signaling proteins independently of AIM2 and RNA polymerase III. J Immunol. 2012;188:394-403 pubmed 出版商 |
| Bartucci M, Svensson S, Romania P, Dattilo R, Patrizii M, Signore M, et al. Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy. Cell Death Differ. 2012;19:768-78 pubmed 出版商 |
| Garimella S, Rocca A, Lipkowitz S. WEE1 inhibition sensitizes basal breast cancer cells to TRAIL-induced apoptosis. Mol Cancer Res. 2012;10:75-85 pubmed 出版商 |
| Büneker C, Yu R, Deedigan L, Mohr A, Zwacka R. IFN-? combined with targeting of XIAP leads to increased apoptosis-sensitisation of TRAIL resistant pancreatic carcinoma cells. Cancer Lett. 2012;316:168-77 pubmed 出版商 |
| Donauer J, Schreck I, Liebel U, Weiss C. Role and interaction of p53, BAX and the stress-activated protein kinases p38 and JNK in benzo(a)pyrene-diolepoxide induced apoptosis in human colon carcinoma cells. Arch Toxicol. 2012;86:329-37 pubmed 出版商 |
