产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Bcl-2 (D17C4) Rabbit mAb (Mouse Preferred)
目录 :
3498
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D17C4
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫沉淀, 免疫组化-石蜡切片
文章摘录数: 45
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 s1f
Fei X, Wu X, Dou Y, Sun K, Guo Q, Zhang L, et al. TRIM22 orchestrates the proliferation of GBMs and the benefits of TMZ by coordinating the modification and degradation of RIG-I. Mol Ther Oncolytics. 2022;26:413-428 pubmed 出版商
  • 免疫印迹; 人类; 1:300; 图 5a
Su Y, Xu J, Gao R, Liu X, Liu T, Li C, et al. The Circ-CYP24A1-miR-224-PRLR Axis Impairs Cell Proliferation and Apoptosis in Recurrent Miscarriage. Front Physiol. 2022;13:778116 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2c
He S, Gao Q, Wu X, Shi J, Zhang Y, Yang J, et al. NAD+ ameliorates endotoxin-induced acute kidney injury in a sirtuin1-dependent manner via GSK-3β/Nrf2 signalling pathway. J Cell Mol Med. 2022;26:1979-1993 pubmed 出版商
  • 免疫印迹; 人类; 图 5g
Lü Z, Liu H, Song N, Liang Y, Zhu J, Chen J, et al. METTL14 aggravates podocyte injury and glomerulopathy progression through N6-methyladenosine-dependent downregulating of Sirt1. Cell Death Dis. 2021;12:881 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1e
Lee Y, Gil E, Jeong I, Kim H, Jang J, Choung Y. Heat Shock Factor 1 Prevents Age-Related Hearing Loss by Decreasing Endoplasmic Reticulum Stress. Cells. 2021;10: pubmed 出版商
  • 免疫印迹; 小鼠; 图 s4c
Bhattarai K, Kim H, Chaudhary M, Ur Rashid M, Kim J, Kim H, et al. TMBIM6 regulates redox-associated posttranslational modifications of IRE1α and ER stress response failure in aging mice and humans. Redox Biol. 2021;47:102128 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3g
Zheleznyak A, Mixdorf M, Marsala L, Prior J, Yang X, Cui G, et al. Orthogonal targeting of osteoclasts and myeloma cells for radionuclide stimulated dynamic therapy induces multidimensional cell death pathways. Theranostics. 2021;11:7735-7754 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1l
Li S, Jin H, Sun G, Zhang C, Wang J, Xu H, et al. Dietary Inorganic Nitrate Protects Hepatic Ischemia-Reperfusion Injury Through NRF2-Mediated Antioxidative Stress. Front Pharmacol. 2021;12:634115 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
  • 免疫印迹; 人类; 图 5b
Bai Y, Pei W, Zhang X, Zheng H, Hua C, Min J, et al. ApoM is an important potential protective factor in the pathogenesis of primary liver cancer. J Cancer. 2021;12:4661-4671 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5e
Park J, Kam T, Lee S, Park H, Oh Y, Kwon S, et al. Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer's disease. Acta Neuropathol Commun. 2021;9:78 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7c
Zhou H, Li G, Wang Y, Jiang R, Li Y, Wang H, et al. Microbial Metabolite Sodium Butyrate Attenuates Cartilage Degradation by Restoring Impaired Autophagy and Autophagic Flux in Osteoarthritis Development. Front Pharmacol. 2021;12:659597 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4a
Yin S, Li L, Tao Y, Yu J, Wei S, Liu M, et al. The Inhibitory Effect of Artesunate on Excessive Endoplasmic Reticulum Stress Alleviates Experimental Colitis in Mice. Front Pharmacol. 2021;12:629798 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5b
  • 免疫印迹; 人类; 图 5a
Kim D, Park J, Choi H, Kim C, Bae E, Ma S, et al. The critical role of FXR is associated with the regulation of autophagy and apoptosis in the progression of AKI to CKD. Cell Death Dis. 2021;12:320 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3d
Chen S, Zhang H, Li J, Shi J, Tang H, Zhang Y, et al. Tripartite Motif-Containing 27 Attenuates Liver Ischemia/Reperfusion Injury by Suppressing Transforming Growth Factor β-Activated Kinase 1 (TAK1) by TAK1 Binding Protein 2/3 Degradation. Hepatology. 2021;73:738-758 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 7a
Zhao J, Li G, Zhao X, Lin X, Gao Y, Raimundo N, et al. Down-regulation of AMPK signaling pathway rescues hearing loss in TFB1 transgenic mice and delays age-related hearing loss. Aging (Albany NY). 2020;12:5590-5611 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5c
  • 免疫印迹; 小鼠; 图 1d
Xiang S, Chen K, Xu L, Wang T, Guo C. Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway. Drug Des Devel Ther. 2020;14:129-143 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2c
Cui J, Duan J, Chu J, Guo C, Xi M, Li Y, et al. Chikusetsu saponin IVa protects pancreatic β cell against intermittent high glucose-induced injury by activating Wnt/β-catenin/TCF7L2 pathway. Aging (Albany NY). 2020;12:1591-1609 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4c
Moya I, Castaldo S, Van den Mooter L, Soheily S, Sansores Garcia L, Jacobs J, et al. Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice. Science. 2019;366:1029-1034 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3a
Sul O, Rajasekaran M, Park H, Suh J, Choi H. MicroRNA-29b Enhances Osteoclast Survival by Targeting BCL-2-Modifying Factor after Lipopolysaccharide Stimulation. Oxid Med Cell Longev. 2019;2019:6018180 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s3d, s6c, s6f
He M, Chaurushiya M, Webster J, Kummerfeld S, Reja R, Chaudhuri S, et al. Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1. Science. 2019;364:283-285 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3a
LeBlanc L, Lee B, Yu A, Kim M, Kambhampati A, Dupont S, et al. Yap1 safeguards mouse embryonic stem cells from excessive apoptosis during differentiation. elife. 2018;7: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2h
Li H, Feng J, Zhang Y, Feng J, Wang Q, Zhao S, et al. Mst1 deletion attenuates renal ischaemia-reperfusion injury: The role of microtubule cytoskeleton dynamics, mitochondrial fission and the GSK3β-p53 signalling pathway. Redox Biol. 2019;20:261-274 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1h
Zhao H, Pan W, Chen L, Luo Y, Xu R. Nur77 promotes cerebral ischemia-reperfusion injury via activating INF2-mediated mitochondrial fragmentation. J Mol Histol. 2018;49:599-613 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2f
Tan X, Banerjee P, Liu X, Yu J, Gibbons D, Wu P, et al. The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network. J Clin Invest. 2018;128:1267-1282 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 4d
Cen M, Hu P, Cai Z, Fang T, Zhang J, Lu M. TIEG1 deficiency confers enhanced myocardial protection in the infarcted heart by mediating the Pten/Akt signalling pathway. Int J Mol Med. 2017;39:569-578 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1a
Su F, Myers V, Knezevic T, Wang J, Gao E, Madesh M, et al. Bcl-2-associated athanogene 3 protects the heart from ischemia/reperfusion injury. JCI Insight. 2016;1:e90931 pubmed 出版商
  • 免疫组化; 小鼠; 图 5c
Li J, Chen K, Li S, Liu T, Wang F, Xia Y, et al. Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis. PLoS ONE. 2016;11:e0152570 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Barroso González J, Auclair S, Luan S, Thomas L, Atkins K, Aslan J, et al. PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage. Cell Death Differ. 2016;23:1448-57 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Antonucci L, Fagman J, Kim J, Todoric J, Gukovsky I, Mackey M, et al. Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress. Proc Natl Acad Sci U S A. 2015;112:E6166-74 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
  • 免疫印迹; 人类; 图 2b
Bresin A, Callegari E, D Abundo L, Cattani C, Bassi C, Zagatti B, et al. miR-181b as a therapeutic agent for chronic lymphocytic leukemia in the Eµ-TCL1 mouse model. Oncotarget. 2015;6:19807-18 pubmed
  • 免疫印迹; 小鼠; 1:1000; 图 6a
Chen W, Xu B, Xiao A, Liu L, Fang X, Liu R, et al. TRPM7 inhibitor carvacrol protects brain from neonatal hypoxic-ischemic injury. Mol Brain. 2015;8:11 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 7
Tao W, Moore R, Smith E, Xu X. Hormonal induction and roles of Disabled-2 in lactation and involution. PLoS ONE. 2014;9:e110737 pubmed 出版商
  • 免疫印迹; 小鼠
Crowther A, Gama V, Bevilacqua A, Chang S, Yuan H, Deshmukh M, et al. Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma. J Neurosci. 2013;33:18098-108 pubmed 出版商
Shahbandi A, Rao S, Anderson A, Frey W, Olayiwola J, Ungerleider N, et al. BH3 mimetics selectively eliminate chemotherapy-induced senescent cells and improve response in TP53 wild-type breast cancer. Cell Death Differ. 2020;: pubmed 出版商
Shin M, Yu J, Lee J, Ji Y, Joung H, Han Y, et al. A Hydroxypropyl Methylcellulose-Based Solid Dispersion of Curcumin with Enhanced Bioavailability and its Hepatoprotective Activity. Biomolecules. 2019;9: pubmed 出版商
Shiozaki Y, Okamura K, Kohno S, Keenan A, Williams K, Zhao X, et al. The CDK9-cyclin T1 complex mediates saturated fatty acid-induced vascular calcification by inducing expression of the transcription factor CHOP. J Biol Chem. 2018;293:17008-17020 pubmed 出版商
Feng L, Vujicic S, Dietrich M, Litbarg N, Setty S, Antoni A, et al. Repeated exposure of epithelial cells to apoptotic cells induces the specific selection of an adaptive phenotype: Implications for tumorigenesis. J Biol Chem. 2018;293:10245-10263 pubmed 出版商
Abdulrahman B, Abdelaziz D, Schatzl H. Autophagy regulates exosomal release of prions in neuronal cells. J Biol Chem. 2018;293:8956-8968 pubmed 出版商
Li Y, Liang Y, Sang Y, Song X, Zhang H, Liu Y, et al. MiR-770 suppresses the chemo-resistance and metastasis of triple negative breast cancer via direct targeting of STMN1. Cell Death Dis. 2018;9:14 pubmed 出版商
Lee P, Zhu Z, Hachmann J, Nojima T, Kitamura D, Salvesen G, et al. Differing Requirements for MALT1 Function in Peripheral B Cell Survival and Differentiation. J Immunol. 2017;198:1066-1080 pubmed 出版商
Weng X, Wang L, Chen H, Liu X, Qiu T, Chen Z. Ischemic postconditioning inhibits apoptosis in an in vitro proximal tubular cell model. Mol Med Rep. 2015;12:99-104 pubmed 出版商
Sun H, Xu B, Chen W, Xiao A, Turlova E, Alibraham A, et al. Neuronal K(ATP) channels mediate hypoxic preconditioning and reduce subsequent neonatal hypoxic-ischemic brain injury. Exp Neurol. 2015;263:161-71 pubmed 出版商
Zhang C, Huang C, Tian Y, Li X. Polyol pathway exacerbated ischemia/reperfusion-induced injury in steatotic liver. Oxid Med Cell Longev. 2014;2014:963629 pubmed 出版商
Fang F, Liu G, Zhou X, Yang S, Reich H, Williams V, et al. Loss of ACE2 exacerbates murine renal ischemia-reperfusion injury. PLoS ONE. 2013;8:e71433 pubmed 出版商
Baumgartner C, Yagita H, Malherbe L. A TCR affinity threshold regulates memory CD4 T cell differentiation following vaccination. J Immunol. 2012;189:2309-17 pubmed 出版商
产品信息
SKU号 :
3498S
产品名称 :
Bcl-2 (D17C4) Rabbit mAb (Mouse Preferred)
规格 :
100微升
Price-(USD) :
235美元
物种x :
H, M
应用 :
免疫沉淀
产品种类 :
凋亡
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
26
宿主 :
靶标 :
Bcl-2
最初蛋白 :
Bcl-2
别名 :
Apoptosis regulator Bcl-2,B-cell CLL/lymphoma 2,BCL2,Bcl-2
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。