产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Sox2(D6D9)XP®兔单克隆抗体
目录 :
3579
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D6D9
反应物种 :
人类, 小鼠, ,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 70
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:100; 图 s1c
Elhussieny A, Nogami K, Sakai Takemura F, Maruyama Y, Takemura N, Soliman W, et al. Mesenchymal stem cells derived from human induced pluripotent stem cells improve the engraftment of myogenic cells by secreting urokinase-type plasminogen activator receptor (uPAR). Stem Cell Res Ther. 2021;12:532 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50; 图 3a
  • 免疫印迹; 人类; 1:500; 图 3b
Generali M, Satheesha S, Bode P, Wanner D, Schafer B, Casanova E. High Frequency of Tumor Propagating Cells in Fusion-Positive Rhabdomyosarcoma. Genes (Basel). 2021;12: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4b
Lo Cascio C, McNamara J, Melendez E, Lewis E, Dufault M, Sanai N, et al. Nonredundant, isoform-specific roles of HDAC1 in glioma stem cells. JCI Insight. 2021;6: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7g
Yin H, Wang J, Li H, Yu Y, Wang X, Lu L, et al. Extracellular matrix protein-1 secretory isoform promotes ovarian cancer through increasing alternative mRNA splicing and stemness. Nat Commun. 2021;12:4230 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 1b
Calvo Garrido J, Winn D, Maffezzini C, Wedell A, Freyer C, Falk A, et al. Protocol for the derivation, culturing, and differentiation of human iPS-cell-derived neuroepithelial stem cells to study neural differentiation in vitro. STAR Protoc. 2021;2:100528 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 1b
Yamamura Y, Furuichi K, Murakawa Y, Hirabayashi S, Yoshihara M, Sako K, et al. Identification of candidate PAX2-regulated genes implicated in human kidney development. Sci Rep. 2021;11:9123 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3b
Aban C, Lombardi A, Neiman G, Biani M, La Greca A, Waisman A, et al. Downregulation of E-cadherin in pluripotent stem cells triggers partial EMT. Sci Rep. 2021;11:2048 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4b
Lu M, Qin X, Zhou Y, Li G, Liu Z, Geng X, et al. Long non-coding RNA LINC00665 promotes gemcitabine resistance of Cholangiocarcinoma cells via regulating EMT and stemness properties through miR-424-5p/BCL9L axis. Cell Death Dis. 2021;12:72 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4b
Li W, Zhang N, Jin C, Long M, Rajabi H, Yasumizu Y, et al. MUC1-C drives stemness in progression of colitis to colorectal cancer. JCI Insight. 2020;5: pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 7a
Gunne Braden A, Sullivan A, Gharibi B, Sheriff R, Maity A, Wang Y, et al. GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells. Cell Stem Cell. 2020;26:693-706.e9 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Chen J, Chen S, Zhuo L, Zhu Y, Zheng H. Regulation of cancer stem cell properties, angiogenesis, and vasculogenic mimicry by miR-450a-5p/SOX2 axis in colorectal cancer. Cell Death Dis. 2020;11:173 pubmed 出版商
  • 免疫印迹; 人类; 图 1d
Chandrasekaran B, Dahiya N, Tyagi A, Kolluru V, Saran U, Baby B, et al. Chronic exposure to cadmium induces a malignant transformation of benign prostate epithelial cells. Oncogenesis. 2020;9:23 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 s3a
Rahman M, Wruck W, Spitzhorn L, Nguyen L, Bohndorf M, Martins S, et al. The FGF, TGFβ and WNT axis Modulate Self-renewal of Human SIX2+ Urine Derived Renal Progenitor Cells. Sci Rep. 2020;10:739 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5c
Zhan Y, Li R, Feng C, Li X, Huang S, Wang L, et al. Chlorogenic acid inhibits esophageal squamous cell carcinoma growth in vitro and in vivo by downregulating the expression of BMI1 and SOX2. Biomed Pharmacother. 2020;121:109602 pubmed 出版商
  • 免疫组化; 小鼠; 图 4c
Kim G, Rincon Fernandez Pacheco D, Saxon D, Yang A, Sabet S, Dutra Clarke M, et al. Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements. Cell. 2019;179:251-267.e24 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Sin Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, et al. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell. 2019;36:51-67.e7 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5f
Lin Q, Li S, Jiang N, Shao X, Zhang M, Jin H, et al. PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation. Redox Biol. 2019;26:101254 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s1g
Sonego M, Pellarin I, Costa A, Vinciguerra G, Coan M, Kraut A, et al. USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability. Sci Adv. 2019;5:eaav3235 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Wang Z, Feng X, Molinolo A, Martin D, Vitale Cross L, Nohata N, et al. 4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer. Cancer Res. 2019;: pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 4a
  • 免疫组化; 人类; 1:200; 图 8b
  • 免疫印迹; 人类; 1:1000; 图 4h
Wang J, Xu S, Duan J, Yi L, Guo Y, Shi Y, et al. Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1-SOX2 positive-feedback loop. Nat Neurosci. 2019;22:91-105 pubmed 出版商
  • 免疫组化; 人类; 1:250; 图 1c
Weltner J, Balboa D, Katayama S, Bespalov M, Krjutskov K, Jouhilahti E, et al. Human pluripotent reprogramming with CRISPR activators. Nat Commun. 2018;9:2643 pubmed 出版商
  • 免疫组化; 人类; 1:160; 图 5c
Kogut I, McCarthy S, Pavlova M, Astling D, Chen X, Jakimenko A, et al. High-efficiency RNA-based reprogramming of human primary fibroblasts. Nat Commun. 2018;9:745 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5g
Wu X, Dao Thi V, Huang Y, Billerbeck E, Saha D, Hoffmann H, et al. Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell. 2018;172:423-438.e25 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3b
Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 2a
  • 免疫细胞化学; 人类; 1:200; 图 3h
Shi Y, Ping Y, Zhou W, He Z, Chen C, Bian B, et al. Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth. Nat Commun. 2017;8:15080 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 6b
  • 免疫细胞化学; 人类; 图 2c
  • 免疫印迹; 人类; 图 2a
Yoon C, Cho S, Chang K, Park D, Ryeom S, Yoon S. Role of Rac1 Pathway in Epithelial-to-Mesenchymal Transition and Cancer Stem-like Cell Phenotypes in Gastric Adenocarcinoma. Mol Cancer Res. 2017;15:1106-1116 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3b
Bharathan S, Manian K, Aalam S, Palani D, Deshpande P, Pratheesh M, et al. Systematic evaluation of markers used for the identification of human induced pluripotent stem cells. Biol Open. 2017;6:100-108 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3b
Xiao Y, Ma H, Wan P, Qin D, Wang X, Zhang X, et al. Trp-Asp (WD) Repeat Domain 1 Is Essential for Mouse Peri-implantation Development and Regulates Cofilin Phosphorylation. J Biol Chem. 2017;292:1438-1448 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:500; 图 s1b
  • 免疫印迹; 人类; 1:1000; 图 2f
Katsushima K, Natsume A, Ohka F, Shinjo K, Hatanaka A, Ichimura N, et al. Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment. Nat Commun. 2016;7:13616 pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Sareddy G, Viswanadhapalli S, Surapaneni P, Suzuki T, Brenner A, Vadlamudi R. Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathway. Oncogene. 2017;36:2423-2434 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 s10b
Zeltner N, Fattahi F, Dubois N, Saurat N, Lafaille F, Shang L, et al. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia. Nat Med. 2016;22:1421-1427 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2
Lee E, Wang J, Yumoto K, Jung Y, Cackowski F, Decker A, et al. DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis. Neoplasia. 2016;18:553-66 pubmed 出版商
  • 免疫印迹; 人类; 图 5e
Lv D, Yu S, Ping Y, Wu H, Zhao X, Zhang H, et al. A three-dimensional collagen scaffold cell culture system for screening anti-glioma therapeutics. Oncotarget. 2016;7:56904-56914 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2c
Mansouri S, Singh S, Alamsahebpour A, Burrell K, Li M, Karabork M, et al. DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma. Oncotarget. 2016;7:56431-56446 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1d
Pinet S, Bessette B, Vedrenne N, Lacroix A, Richard L, Jauberteau M, et al. TrkB-containing exosomes promote the transfer of glioblastoma aggressiveness to YKL-40-inactivated glioblastoma cells. Oncotarget. 2016;7:50349-50364 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 2
Francis K, Ton A, Xin Y, O Halloran P, Wassif C, Malik N, et al. Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes. Nat Med. 2016;22:388-96 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 图 1d
  • 免疫印迹; 人类; 1:1000; 图 1c
Ren C, Ren T, Yang K, Wang S, Bao X, Zhang F, et al. Inhibition of SOX2 induces cell apoptosis and G1/S arrest in Ewing's sarcoma through the PI3K/Akt pathway. J Exp Clin Cancer Res. 2016;35:44 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Xu M, Bian S, Li J, He J, Chen H, Ge L, et al. MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells. Oncotarget. 2016;7:14476-85 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 1e
Balboa D, Weltner J, Eurola S, Trokovic R, Wartiovaara K, Otonkoski T. Conditionally Stabilized dCas9 Activator for Controlling Gene Expression in Human Cell Reprogramming and Differentiation. Stem Cell Reports. 2015;5:448-59 pubmed 出版商
  • 免疫印迹; 人类; 图 5d
  • 免疫印迹; 小鼠; 图 1a
Bora Singhal N, Perumal D, Nguyen J, Chellappan S. Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer. Neoplasia. 2015;17:538-51 pubmed 出版商
  • 免疫组化; 犬; 1:50; 图 2
Kegler K, Spitzbarth I, Imbschweiler I, Wewetzer K, Baumgärtner W, Seehusen F. Contribution of Schwann Cells to Remyelination in a Naturally Occurring Canine Model of CNS Neuroinflammation. PLoS ONE. 2015;10:e0133916 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 3
  • 免疫印迹; 人类; 1:1000; 图 4
Zucha M, Wu A, Lee W, Wang L, Lin W, Yuan C, et al. Bruton's tyrosine kinase (Btk) inhibitor ibrutinib suppresses stem-like traits in ovarian cancer. Oncotarget. 2015;6:13255-68 pubmed
  • 免疫细胞化学; 人类; 图 s4d
Di Cristofori A, Ferrero S, Bertolini I, Gaudioso G, Russo M, Berno V, et al. The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma. Oncotarget. 2015;6:17514-31 pubmed
  • 免疫印迹; 人类; 1:500; 图 1
Jung K, Gupta N, Wang P, Lewis J, Gopal K, Wu F, et al. Triple negative breast cancers comprise a highly tumorigenic cell subpopulation detectable by its high responsiveness to a Sox2 regulatory region 2 (SRR2) reporter. Oncotarget. 2015;6:10366-73 pubmed
  • 免疫细胞化学; 人类; 图 1
Ma R, Latif R, Davies T. Human embryonic stem cells form functional thyroid follicles. Thyroid. 2015;25:455-61 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 表 2
Weissferdt A, Rodriguez Canales J, Liu H, Fujimoto J, Wistuba I, Moran C. Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers. Hum Pathol. 2015;46:376-83 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250
Muchkaeva I, Dashinimaev E, Artyuhov A, Myagkova E, Vorotelyak E, Yegorov Y, et al. Generation of iPS Cells from Human Hair Follice Dermal Papilla Cells. Acta Naturae. 2014;6:45-53 pubmed
  • 免疫印迹; 人类; 1:1000; 图 1c
Mouallif M, Albert A, Zeddou M, Ennaji M, Delvenne P, Guenin S. Expression profile of undifferentiated cell transcription factor 1 in normal and cancerous human epithelia. Int J Exp Pathol. 2014;95:251-9 pubmed 出版商
  • 流式细胞仪; 人类
Liu H, Zhang W, Jia Y, Yu Q, Grau G, Peng L, et al. Single-cell clones of liver cancer stem cells have the potential of differentiating into different types of tumor cells. Cell Death Dis. 2013;4:e857 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50
Mao X, Hütt Cabezas M, Orr B, Weingart M, Taylor I, Rajan A, et al. LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program. Oncotarget. 2013;4:1050-64 pubmed
Maiti S, Mondal S, Satyavarapu E, Mandal C. mTORC2 regulates hedgehog pathway activity by promoting stability to Gli2 protein and its nuclear translocation. Cell Death Dis. 2017;8:e2926 pubmed 出版商
Bhargava S, Visvanathan A, Patil V, Kumar A, Kesari S, Das S, et al. IGF2 mRNA binding protein 3 (IMP3) promotes glioma cell migration by enhancing the translation of RELA/p65. Oncotarget. 2017;8:40469-40485 pubmed 出版商
Wu C, Zhang H, Gupta N, Alshareef A, Wang Q, Huang Y, et al. A positive feedback loop involving the Wnt/?-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma. J Hematol Oncol. 2016;9:120 pubmed
Tominaga K, Shimamura T, Kimura N, Murayama T, Matsubara D, Kanauchi H, et al. Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells. Oncogene. 2017;36:1276-1286 pubmed 出版商
Schaefer T, Wang H, Mir P, Konantz M, Pereboom T, Paczulla A, et al. Molecular and functional interactions between AKT and SOX2 in breast carcinoma. Oncotarget. 2015;6:43540-56 pubmed 出版商
Kang W, Kim S, Cho H, Jin J, Lee J, Joo K, et al. Talin1 targeting potentiates anti-angiogenic therapy by attenuating invasion and stem-like features of glioblastoma multiforme. Oncotarget. 2015;6:27239-51 pubmed 出版商
Wong H, Fatimy R, Onodera C, Wei Z, Yi M, Mohan A, et al. The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma. Mol Ther. 2015;23:1234-1247 pubmed 出版商
Shibuya K, Okada M, Suzuki S, Seino M, Seino S, Takeda H, et al. Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells. Oncotarget. 2015;6:651-61 pubmed
Miyatake Y, Sheehy N, Ikeshita S, Hall W, Kasahara M. Anchorage-dependent multicellular aggregate formation induces CD44 high cancer stem cell-like ATL cells in an NF-κB- and vimentin-dependent manner. Cancer Lett. 2015;357:355-63 pubmed 出版商
Sandstrom R, Foret M, Grow D, Haugen E, Rhodes C, Cardona A, et al. Epigenetic regulation by chromatin activation mark H3K4me3 in primate progenitor cells within adult neurogenic niche. Sci Rep. 2014;4:5371 pubmed 出版商
Yang W, Lee Y, Jones A, Woolnough J, Zhou D, Dai Q, et al. The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitment. Nat Commun. 2014;5:3818 pubmed 出版商
Huang P, Watanabe M, Kaku H, Ueki H, Noguchi H, Sugimoto M, et al. Cancer stem cell-like characteristics of a CD133+ subpopulation in the J82 human bladder cancer cell line. Mol Clin Oncol. 2013;1:180-184 pubmed
Rybak A, Tang D. SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells. Cell Signal. 2013;25:2734-42 pubmed 出版商
Bareiss P, Paczulla A, Wang H, Schairer R, Wiehr S, Kohlhofer U, et al. SOX2 expression associates with stem cell state in human ovarian carcinoma. Cancer Res. 2013;73:5544-55 pubmed 出版商
da Cunha J, da Costa Neves A, Kerkis I, da Silva M. Pluripotent stem cell transcription factors during human odontogenesis. Cell Tissue Res. 2013;353:435-41 pubmed 出版商
Kregel S, Kiriluk K, Rosen A, Cai Y, Reyes E, Otto K, et al. Sox2 is an androgen receptor-repressed gene that promotes castration-resistant prostate cancer. PLoS ONE. 2013;8:e53701 pubmed 出版商
Katz S, Fisher J, Correll M, Bronson R, Ligon K, Walensky L. Brain and testicular tumors in mice with progenitor cells lacking BAX and BAK. Oncogene. 2013;32:4078-85 pubmed 出版商
Xu D, Yang C, Proescholdt M, Bründl E, Brawanski A, Fang X, et al. Neuronatin in a subset of glioblastoma multiforme tumor progenitor cells is associated with increased cell proliferation and shorter patient survival. PLoS ONE. 2012;7:e37811 pubmed 出版商
Polak U, Hirsch C, Ku S, GOTTESFELD J, Dent S, Napierala M. Selecting and isolating colonies of human induced pluripotent stem cells reprogrammed from adult fibroblasts. J Vis Exp. 2012;: pubmed 出版商
Anaka M, Freyer C, Gedye C, Caballero O, Davis I, Behren A, et al. Stem cell media culture of melanoma results in the induction of a nonrepresentative neural expression profile. Stem Cells. 2012;30:336-43 pubmed 出版商
产品信息
SKU号 :
3579S
产品名称 :
Sox2(D6D9)XP®兔单克隆抗体
规格 :
100微升
Price-(USD) :
260美元
物种x :
H, (Mk, B, Dg, Hr)
应用 :
流式细胞仪
产品种类 :
发育生物学
运输温度 :
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
35
宿主 :
靶标 :
Sox2
最初蛋白 :
SOX2
别名 :
ANOP3,MCOPS3,MGC2413,SOX2,SRY (sex determining region Y)-box 2,SRY-related HMG-box gene 2,Transcription factor SOX-2,transcription factor SOX2
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。