产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
磷酸化eIF2α(Ser51)(119A11)兔单克隆抗体
目录 :
3597
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
119A11
反应物种 :
仓鼠, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 90
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 3a
Bhattarai K, Kim H, Chaudhary M, Ur Rashid M, Kim J, Kim H, et al. TMBIM6 regulates redox-associated posttranslational modifications of IRE1α and ER stress response failure in aging mice and humans. Redox Biol. 2021;47:102128 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4b
Swarnkar S, Avchalumov Y, Espadas I, Grinman E, Liu X, Raveendra B, et al. Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation. Cell Rep. 2021;36:109369 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6h
  • 免疫印迹; 小鼠; 1:1000; 图 5c
Zhou Y, Ye X, Zhang C, Wang J, Guan Z, Yan J, et al. Ufl1 deficiency causes kidney atrophy associated with disruption of endoplasmic reticulum homeostasis. J Genet Genomics. 2021;48:403-410 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7a
Pereira R, Marti A, Olvera A, Tadinada S, Bjorkman S, Weatherford E, et al. OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21. elife. 2021;10: pubmed 出版商
  • 免疫印迹; 人类; 图 5a
  • 免疫印迹; 小鼠; 图 6d
Chen Y, Hu W, Li Q, Zhao S, Zhao D, Zhang S, et al. NGBR is required to ameliorate type 2 diabetes in mice by enhancing insulin sensitivity. J Biol Chem. 2021;296:100624 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 4l
Mick E, Titov D, Skinner O, Sharma R, Jourdain A, Mootha V. Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Lee D, Kam M, Lee S, Lee H, Lee D. Peroxiredoxin 5 deficiency exacerbates iron overload-induced neuronal death via ER-mediated mitochondrial fission in mouse hippocampus. Cell Death Dis. 2020;11:204 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b, s6f
Smith H, Freeman O, Butcher A, Holmqvist S, Humoud I, Schätzl T, et al. Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration. Neuron. 2020;: pubmed 出版商
  • 免疫印迹; 仓鼠; 1:1000; 图 4a
Yong J, Bischof H, Burgstaller S, Siirin M, Murphy A, Malli R, et al. Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca2. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Pringle E, Robinson C, McCormick C. Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication Interferes with mTORC1 Regulation of Autophagy and Viral Protein Synthesis. J Virol. 2019;93: pubmed 出版商
  • 免疫印迹; 小鼠; 图 4d
Wu J, Ma S, Sandhoff R, Ming Y, Hotz Wagenblatt A, Timmerman V, et al. Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness. Immunity. 2019;50:1218-1231.e5 pubmed 出版商
  • 免疫印迹; 人类; 图 2g
Zhang P, Fan B, Yang P, Temirov J, Messing J, Kim H, et al. Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 图 s1e
Avolio R, Järvelin A, Mohammed S, Agliarulo I, Condelli V, Zoppoli P, et al. Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation. Nucleic Acids Res. 2018;46:12067-12086 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 5d
  • 免疫印迹; 人类; 1:1000; 图 5a
Sonobe Y, Ghadge G, Masaki K, Sendoel A, Fuchs E, Roos R. Translation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress. Neurobiol Dis. 2018;116:155-165 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6a
Pereira R, Tadinada S, Zasadny F, Oliveira K, Pires K, Olvera A, et al. OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance. EMBO J. 2017;36:2126-2145 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Lee C, Hanna A, Wang H, Dagnino Acosta A, Joshi A, Knoblauch M, et al. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017;8:14659 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 6a
Xiong G, Hindi S, Mann A, Gallot Y, Bohnert K, Cavener D, et al. The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration. elife. 2017;6: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2b
Dimasi P, Quintiero A, Shelkovnikova T, Buchman V. Modulation of p-eIF2α cellular levels and stress granule assembly/disassembly by trehalose. Sci Rep. 2017;7:44088 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4a
Liu J, Wang Y, Song L, Zeng L, Yi W, Liu T, et al. A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability. Nat Commun. 2017;8:14186 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4h
Sendoel A, Dunn J, Rodriguez E, Naik S, Gomez N, Hurwitz B, et al. Translation from unconventional 5' start sites drives tumour initiation. Nature. 2017;541:494-499 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1g
Su C, Gao X, Yang W, Zhao Y, Fu X, Cui X, et al. Phosphorylation of Tudor-SN, a novel substrate of JNK, is involved in the efficient recruitment of Tudor-SN into stress granules. Biochim Biophys Acta Mol Cell Res. 2017;1864:562-571 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4c
Mukhopadhyay C, Triplett A, Bargar T, HECKMAN C, Wagner K, Naramura M. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation. Proc Natl Acad Sci U S A. 2016;113:E8228-E8237 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 3
Hu J, Li B, Apisa L, Yu H, Entenman S, Xu M, et al. ER stress inhibitor attenuates hearing loss and hair cell death in Cdh23erl/erl mutant mice. Cell Death Dis. 2016;7:e2485 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Li D, Xie B, Wu X, Li J, Ding Y, Wen X, et al. Late-stage inhibition of autophagy enhances calreticulin surface exposure. Oncotarget. 2016;7:80842-80854 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Carpentier K, Esparo N, Child S, Geballe A. A Single Amino Acid Dictates Protein Kinase R Susceptibility to Unrelated Viral Antagonists. PLoS Pathog. 2016;12:e1005966 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6
Bai Y, Dong Z, Shang Q, Zhao H, Wang L, Guo C, et al. Pdcd4 Is Involved in the Formation of Stress Granule in Response to Oxidized Low-Density Lipoprotein or High-Fat Diet. PLoS ONE. 2016;11:e0159568 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 8D
  • 免疫印迹; 人类; 1:1000; 图 7A
Zhou X, Wei Y, Qiu S, Xu Y, Zhang T, Zhang S. Propofol Decreases Endoplasmic Reticulum Stress-Mediated Apoptosis in Retinal Pigment Epithelial Cells. PLoS ONE. 2016;11:e0157590 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2e
Xu Z, Bu Y, Chitnis N, Koumenis C, Fuchs S, Diehl J. miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis. Nat Commun. 2016;7:11422 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s3
Aaes T, Kaczmarek A, Delvaeye T, De Craene B, De Koker S, Heyndrickx L, et al. Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. Cell Rep. 2016;15:274-87 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Bretin A, Carrière J, Dalmasso G, Bergougnoux A, B chir W, Maurin A, et al. Activation of the EIF2AK4-EIF2A/eIF2?-ATF4 pathway triggers autophagy response to Crohn disease-associated adherent-invasive Escherichia coli infection. Autophagy. 2016;12:770-83 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Colangelo T, Polcaro G, Ziccardi P, Muccillo L, Galgani M, Pucci B, et al. The miR-27a-calreticulin axis affects drug-induced immunogenic cell death in human colorectal cancer cells. Cell Death Dis. 2016;7:e2108 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Lei Y, Kansy B, Li J, Cong L, Liu Y, Trivedi S, et al. EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complex. Oncogene. 2016;35:4698-707 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3
Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4
Lancaster G, Kammoun H, Kraakman M, Kowalski G, Bruce C, Febbraio M. PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications. Nat Commun. 2016;7:10626 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50; 图 1a
  • 免疫印迹; 小鼠; 1:1000; 图 1c
El Karoui K, Viau A, Dellis O, Bagattin A, Nguyen C, BARON W, et al. Endoplasmic reticulum stress drives proteinuria-induced kidney lesions via Lipocalin 2. Nat Commun. 2016;7:10330 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 5
Srinivasan R, Henley B, Henderson B, Indersmitten T, Cohen B, Kim C, et al. Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons. J Neurosci. 2016;36:65-79 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 2, 5
Ulbrich L, Favaloro F, Trobiani L, Marchetti V, Patel V, Pascucci T, et al. Autism-associated R451C mutation in neuroligin3 leads to activation of the unfolded protein response in a PC12 Tet-On inducible system. Biochem J. 2016;473:423-34 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Antonucci L, Fagman J, Kim J, Todoric J, Gukovsky I, Mackey M, et al. Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress. Proc Natl Acad Sci U S A. 2015;112:E6166-74 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Sakabe I, Hu R, Jin L, Clarke R, Kasid U. TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling. Breast Cancer Res Treat. 2015;153:285-97 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Cha J, Burnum Johnson K, Bartos A, Li Y, Baker E, Tilton S, et al. Muscle Segment Homeobox Genes Direct Embryonic Diapause by Limiting Inflammation in the Uterus. J Biol Chem. 2015;290:15337-49 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 1
Wong M, Nicholson C, Holloway A, Hardy D. Maternal nicotine exposure leads to impaired disulfide bond formation and augmented endoplasmic reticulum stress in the rat placenta. PLoS ONE. 2015;10:e0122295 pubmed 出版商
  • 免疫印迹; 人类; 图 2g
Dudek Perić A, Ferreira G, Muchowicz A, Wouters J, Prada N, Martin S, et al. Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface-associated calreticulin. Cancer Res. 2015;75:1603-14 pubmed 出版商
  • 免疫组化; 小鼠; 1:300; 图 2a
Filézac de L Etang A, Maharjan N, Cordeiro Braña M, Ruegsegger C, Rehmann R, Goswami A, et al. Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS. Nat Neurosci. 2015;18:227-38 pubmed 出版商
  • 免疫印迹; 小鼠
  • 免疫印迹; 大鼠
Jaishy B, Zhang Q, Chung H, Riehle C, Soto J, Jenkins S, et al. Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity. J Lipid Res. 2015;56:546-61 pubmed 出版商
  • 免疫印迹; 人类
Li W, Ouyang Z, Zhang Q, Wang L, Shen Y, Gu Y, et al. SBF-1 exerts strong anticervical cancer effect through inducing endoplasmic reticulum stress-associated cell death via targeting sarco/endoplasmic reticulum Ca(2+)-ATPase 2. Cell Death Dis. 2014;5:e1581 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Areta J, Hawley J, Ye J, Chan M, Coffey V. Increasing leucine concentration stimulates mechanistic target of rapamycin signaling and cell growth in C2C12 skeletal muscle cells. Nutr Res. 2014;34:1000-7 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Arruda A, Pers B, Parlakgül G, Güney E, Inouye K, Hotamisligil G. Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity. Nat Med. 2014;20:1427-35 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Bhuvanagiri M, Lewis J, Putzker K, Becker J, Leicht S, Krijgsveld J, et al. 5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion. EMBO Mol Med. 2014;6:1593-609 pubmed 出版商
  • 免疫组化; 小鼠; 1:150
Bernard Marissal N, Sunyach C, Marissal T, Raoul C, Pettmann B. Calreticulin levels determine onset of early muscle denervation by fast motoneurons of ALS model mice. Neurobiol Dis. 2015;73:130-6 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Sadleir K, Eimer W, Kaufman R, Osten P, Vassar R. Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease. PLoS ONE. 2014;9:e101643 pubmed 出版商
  • 免疫印迹; 小鼠
Maas N, Singh N, Diehl J. Generation and characterization of an analog-sensitive PERK allele. Cancer Biol Ther. 2014;15:1106-11 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Campos G, Schmidt Heck W, Ghallab A, Rochlitz K, Pütter L, Medinas D, et al. The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity. Arch Toxicol. 2014;88:1267-80 pubmed 出版商
  • 免疫印迹; 小鼠
Ost M, Werner F, Dokas J, Klaus S, Voigt A. Activation of AMPK?2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity. PLoS ONE. 2014;9:e94689 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
  • 免疫印迹; 人类; 1:500
Kaehler C, Isensee J, Hucho T, Lehrach H, Krobitsch S. 5-Fluorouracil affects assembly of stress granules based on RNA incorporation. Nucleic Acids Res. 2014;42:6436-47 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Nagelkerke A, Sweep F, Stegeman H, Grenman R, Kaanders J, Bussink J, et al. Hypoxic regulation of the PERK/ATF4/LAMP3-arm of the unfolded protein response in head and neck squamous cell carcinoma. Head Neck. 2015;37:896-905 pubmed 出版商
  • 免疫印迹; 小鼠
Wang B, Dai S, Dong Z, Sun Y, Song X, Guo C, et al. The modulation of endoplasmic reticulum stress by chemical chaperone upregulates immune negative cytokine IL-35 in apolipoprotein E-deficient mice. PLoS ONE. 2014;9:e87787 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:50
Ní Fhlathartaigh M, McMahon J, Reynolds R, Connolly D, Higgins E, Counihan T, et al. Calreticulin and other components of endoplasmic reticulum stress in rat and human inflammatory demyelination. Acta Neuropathol Commun. 2013;1:37 pubmed 出版商
  • 免疫印迹; 人类
Shang L, Hua H, Foo K, Martínez H, Watanabe K, Zimmer M, et al. β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome. Diabetes. 2014;63:923-33 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Naidoo N, Davis J, Zhu J, Yabumoto M, Singletary K, Brown M, et al. Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism. Aging Cell. 2014;13:131-41 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500
Díaz Villaseñor A, Granados O, González Palacios B, Tovar Palacio C, Torre Villalvazo I, Olivares García V, et al. Differential modulation of the functionality of white adipose tissue of obese Zucker (fa/fa) rats by the type of protein and the amount and type of fat. J Nutr Biochem. 2013;24:1798-809 pubmed 出版商
  • 免疫印迹; 大鼠
Zhuo X, Wu Y, Ni Y, Liu J, Gong M, Wang X, et al. Isoproterenol instigates cardiomyocyte apoptosis and heart failure via AMPK inactivation-mediated endoplasmic reticulum stress. Apoptosis. 2013;18:800-10 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Hou Y, Xue P, Woods C, Wang X, Fu J, Yarborough K, et al. Association between arsenic suppression of adipogenesis and induction of CHOP10 via the endoplasmic reticulum stress response. Environ Health Perspect. 2013;121:237-43 pubmed 出版商
  • 免疫组化; 人类; 1:50
  • 免疫印迹; 人类; 1:1000
Jorgensen E, Stinson A, Shan L, Yang J, Gietl D, Albino A. Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells. BMC Cancer. 2008;8:229 pubmed 出版商
Wu J, Chen Y, Dobbs N, Sakai T, Liou J, Miner J, et al. STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death. J Exp Med. 2019;: pubmed 出版商
Reineke L, Cheema S, Dubrulle J, Neilson J. Chronic starvation induces noncanonical pro-death stress granules. J Cell Sci. 2018;131: pubmed 出版商
Zhao Y, Liu N, Miao G, Chen Y, Zhao H, Zhang H. The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis. Curr Biol. 2018;28:1234-1245.e4 pubmed 出版商
Bu Y, Yoshida A, Chitnis N, Altman B, Tameire F, Oran A, et al. A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival. Nat Cell Biol. 2018;20:104-115 pubmed 出版商
Zhao Y, Chen Y, Miao G, Zhao H, Qu W, Li D, et al. The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation. Mol Cell. 2017;67:974-989.e6 pubmed 出版商
Shah S, Carriveau W, Li J, Campbell S, Kopinski P, Lim H, et al. Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism. Oncotarget. 2016;7:43713-43730 pubmed 出版商
Musner N, Sidoli M, Zambroni D, Del Carro U, Ungaro D, D Antonio M, et al. Perk Ablation Ameliorates Myelination in S63del-Charcot-Marie-Tooth 1B Neuropathy. ASN Neuro. 2016;8: pubmed 出版商
Mendez A, Alfaro J, Morales Soto M, Dar A, McCullagh E, Gotthardt K, et al. Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic. elife. 2015;4: pubmed 出版商
Wu H, Wei L, Fan F, Ji S, Zhang S, Geng J, et al. Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis. Nat Commun. 2015;6:6239 pubmed 出版商
Dixon S, Patel D, Welsch M, Skouta R, Lee E, Hayano M, et al. Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis. elife. 2014;3:e02523 pubmed 出版商
Riddle E, Campbell M, Lang B, Bierer R, Wang Y, Bagley H, et al. Intrauterine growth restriction increases TNF ? and activates the unfolded protein response in male rat pups. J Obes. 2014;2014:829862 pubmed 出版商
Wang C, Wu M, Arvapalli R, Dai X, Mahmood M, Driscoll H, et al. Acetaminophen attenuates obesity-related renal injury through ER-mediated stress mechanisms. Cell Physiol Biochem. 2014;33:1139-48 pubmed 出版商
Kiskinis E, Sandoe J, Williams L, Boulting G, Moccia R, Wainger B, et al. Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1. Cell Stem Cell. 2014;14:781-95 pubmed 出版商
Wang Y, Bettaieb A, Sun C, Deverse J, Radecke C, Mathew S, et al. Triglyceride-rich lipoprotein modulates endothelial vascular cell adhesion molecule (VCAM)-1 expression via differential regulation of endoplasmic reticulum stress. PLoS ONE. 2013;8:e78322 pubmed 出版商
Hocker A, Boileau R, Lantz B, Jewett B, Gilbert J, Dreyer H. Endoplasmic Reticulum Stress Activation during Total Knee Arthroplasty. Physiol Rep. 2013;1:e00052 pubmed
Cawley K, Logue S, Gorman A, Zeng Q, Patterson J, Gupta S, et al. Disruption of microRNA biogenesis confers resistance to ER stress-induced cell death upstream of the mitochondrion. PLoS ONE. 2013;8:e73870 pubmed 出版商
Firczuk M, Gabrysiak M, Barankiewicz J, Domagala A, Nowis D, Kujawa M, et al. GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy. Cell Death Dis. 2013;4:e741 pubmed 出版商
Balakrishnan B, Sen D, Hareendran S, Roshini V, David S, Srivastava A, et al. Activation of the cellular unfolded protein response by recombinant adeno-associated virus vectors. PLoS ONE. 2013;8:e53845 pubmed 出版商
Mans S, Banz Y, Mueller B, Pabst T. The angiogenesis inhibitor vasostatin is regulated by neutrophil elastase-dependent cleavage of calreticulin in AML patients. Blood. 2012;120:2690-9 pubmed
Baker B, Nargund A, Sun T, Haynes C. Protective coupling of mitochondrial function and protein synthesis via the eIF2? kinase GCN-2. PLoS Genet. 2012;8:e1002760 pubmed 出版商
Sharma A, Yilmaz A, Marsh K, Cochrane A, Boris Lawrie K. Thriving under stress: selective translation of HIV-1 structural protein mRNA during Vpr-mediated impairment of eIF4E translation activity. PLoS Pathog. 2012;8:e1002612 pubmed 出版商
Ling S, Lau E, Al Shabeeb A, Nikolic A, Catalano A, Iland H, et al. Response of myeloma to the proteasome inhibitor bortezomib is correlated with the unfolded protein response regulator XBP-1. Haematologica. 2012;97:64-72 pubmed 出版商
De Raedt T, Walton Z, Yecies J, Li D, Chen Y, Malone C, et al. Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors. Cancer Cell. 2011;20:400-13 pubmed 出版商
Wu M, Liu H, Fannin J, Katta A, Wang Y, Arvapalli R, et al. Acetaminophen improves protein translational signaling in aged skeletal muscle. Rejuvenation Res. 2010;13:571-9 pubmed 出版商
Gupta S, Deepti A, Deegan S, Lisbona F, Hetz C, Samali A. HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction. PLoS Biol. 2010;8:e1000410 pubmed 出版商
Kim I, Shu C, Xu W, Shiau C, Grant D, Vasile S, et al. Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1. J Biol Chem. 2009;284:1593-603 pubmed 出版商
产品信息
SKU号 :
3597S
产品名称 :
磷酸化eIF2α(Ser51)(119A11)兔单克隆抗体
规格 :
100微升
Price-(USD) :
274美元
物种x :
H, M, R, Mk, Dm
应用 :
免疫组化(石蜡)
产品种类 :
Translational Control
运输温度 :
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
38
宿主 :
靶标 :
eIF2A(Ser51)磷酸盐
最初蛋白 :
eIF2A
别名 :
EIF-2,EIF2,EIF2A,EIF2S1,Eukaryotic translation initiation factor 2 subunit 1,Eukaryotic translation initiation factor 2 subunit alpha,IF2A,eIF-2-alpha,eIF-2A,eIF-2alpha,eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。