Wang R, Yang D, Liu Y, Ding J, Guo Y, Ding W, et al. Cell cycle exit and neuronal differentiation 1-engineered embryonic neural stem cells enhance neuronal differentiation and neurobehavioral recovery after experimental traumatic brain injury. Neural Regen Res. 2022;17:130-136 pubmed 出版商

Wang Y, Liu I, Chen K, Wu H. NOTCH1 signaling promotes protein stability of HER3 through the AKT pathway in squamous cell carcinoma of head and neck. Oncogenesis. 2021;10:59 pubmed 出版商

Liang F, Wang B, Geng J, You G, Fa J, Zhang M, et al. SORBS2 is a genetic factor contributing to cardiac malformation of 4q deletion syndrome patients. elife. 2021;10: pubmed 出版商

Liu L, Tao T, Liu S, Yang X, Chen X, Liang J, et al. An RFC4/Notch1 signaling feedback loop promotes NSCLC metastasis and stemness. Nat Commun. 2021;12:2693 pubmed 出版商

Nishad R, Mukhi D, Singh A, Motrapu M, Chintala K, Tammineni P, et al. Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria. Cell Death Dis. 2021;12:342 pubmed 出版商

Ni W, Chen Z, Zhou X, Yang R, Yu M, Lu J, et al. Targeting Notch and EGFR signaling in human mucoepidermoid carcinoma. Signal Transduct Target Ther. 2021;6:27 pubmed 出版商

Tendler S, Kanter L, Lewensohn R, Ortiz Villalón C, Viktorsson K, De Petris L. The prognostic implications of Notch1, Hes1, Ascl1, and DLL3 protein expression in SCLC patients receiving platinum-based chemotherapy. PLoS ONE. 2020;15:e0240973 pubmed 出版商

Tan Y, Sementino E, Liu Z, Cai K, Testa J. Wnt signaling mediates oncogenic synergy between Akt and Dlx5 in T-cell lymphomagenesis by enhancing cholesterol synthesis. Sci Rep. 2020;10:15837 pubmed 出版商

Kuang Y, Golan O, Preusse K, Cain B, Christensen C, Salomone J, et al. Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism. elife. 2020;9: pubmed 出版商

Chandrasekaran B, Dahiya N, Tyagi A, Kolluru V, Saran U, Baby B, et al. Chronic exposure to cadmium induces a malignant transformation of benign prostate epithelial cells. Oncogenesis. 2020;9:23 pubmed 出版商

Hu J, Yu J, Gan J, Song N, Shi L, Liu J, et al. Notch1/2/3/4 are prognostic biomarker and correlated with immune infiltrates in gastric cancer. Aging (Albany NY). 2020;12:2595-2609 pubmed 出版商

Liu H, Mei F, Yang W, Wang H, Wong E, Cai J, et al. Epac1 inhibition ameliorates pathological angiogenesis through coordinated activation of Notch and suppression of VEGF signaling. Sci Adv. 2020;6:eaay3566 pubmed 出版商

Lin Q, Chen X, Meng F, Ogawa K, Li M, Song R, et al. ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis. Mol Cancer. 2019;18:156 pubmed 出版商

Wang J, Xu S, Duan J, Yi L, Guo Y, Shi Y, et al. Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1-SOX2 positive-feedback loop. Nat Neurosci. 2019;22:91-105 pubmed 出版商

Mangolini M, Götte F, Moore A, Ammon T, Oelsner M, Lutzny Geier G, et al. Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia. Nat Commun. 2018;9:3839 pubmed 出版商

Frank S, Berger P, Ljungman M, Miranti C. Human prostate luminal cell differentiation requires NOTCH3 induction by p38-MAPK and MYC. J Cell Sci. 2017;130:1952-1964 pubmed 出版商

Mandl M, Zhang S, Ulrich M, Schmoeckel E, Mayr D, Vollmar A, et al. Inhibition of Cdk5 induces cell death of tumor-initiating cells. Br J Cancer. 2017;116:912-922 pubmed 出版商

Hurst L, Dunmore B, Long L, Crosby A, Al Lamki R, Deighton J, et al. TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling. Nat Commun. 2017;8:14079 pubmed 出版商

Revandkar A, Perciato M, Toso A, Alajati A, Chen J, Gerber H, et al. Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence. Nat Commun. 2016;7:13719 pubmed 出版商

Zhang Q, Zhang Y, Parsels J, Lohse I, Lawrence T, Pasca di Magliano M, et al. Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation. Neoplasia. 2016;18:666-673 pubmed 出版商

Kuzmanov U, Guo H, Buchsbaum D, Cosme J, Abbasi C, Isserlin R, et al. Global phosphoproteomic profiling reveals perturbed signaling in a mouse model of dilated cardiomyopathy. Proc Natl Acad Sci U S A. 2016;113:12592-12597 pubmed

Jordan N, Bardia A, Wittner B, Benes C, Ligorio M, Zheng Y, et al. HER2 expression identifies dynamic functional states within circulating breast cancer cells. Nature. 2016;537:102-106 pubmed 出版商

Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed 出版商

Zhang P, He D, Chen Z, Pan Q, Du F, Zang X, et al. Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancer. Biochem Pharmacol. 2016;118:18-30 pubmed 出版商

Fan C, Jia L, Zheng Y, Jin C, Liu Y, Liu H, et al. MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network. Stem Cell Reports. 2016;7:236-48 pubmed 出版商

Zeng J, Jing Y, Shi R, Pan X, Lai F, Liu W, et al. Autophagy regulates biliary differentiation of hepatic progenitor cells through Notch1 signaling pathway. Cell Cycle. 2016;15:1602-10 pubmed 出版商

Noh H, Hah Y, Ha J, Kang M, Zada S, Rha S, et al. Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. Oncotarget. 2016;7:4632-46 pubmed 出版商

Zhang Y, Yu J, Lee C, Xu B, Sartor M, Koenig R. Genomic binding and regulation of gene expression by the thyroid carcinoma-associated PAX8-PPARG fusion protein. Oncotarget. 2015;6:40418-32 pubmed 出版商

Liu Z, Brunskill E, Varnum Finney B, Zhang C, Zhang A, Jay P, et al. The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis. Development. 2015;142:2452-63 pubmed 出版商

Jäger W, Xue H, Hayashi T, Janssen C, Awrey S, Wyatt A, et al. Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies. Oncotarget. 2015;6:21522-32 pubmed

Yang L, Zhang S, George S, Teng R, You X, Xu M, et al. Targeting Notch1 and proteasome as an effective strategy to suppress T-cell lymphoproliferative neoplasms. Oncotarget. 2015;6:14953-69 pubmed

Nakamura M, Shibata K, Hatano S, Sato T, Ohkawa Y, Yamada H, et al. A genome-wide analysis identifies a notch-RBP-Jκ-IL-7Rα axis that controls IL-17-producing γδ T cell homeostasis in mice. J Immunol. 2015;194:243-51 pubmed 出版商

Yoshida R, Nagata M, Nakayama H, Niimori Kita K, Hassan W, Tanaka T, et al. The pathological significance of Notch1 in oral squamous cell carcinoma. Lab Invest. 2013;93:1068-81 pubmed 出版商

El Hindy N, Keyvani K, Pagenstecher A, Dammann P, Sandalcioglu I, Sure U, et al. Implications of Dll4-Notch signaling activation in primary glioblastoma multiforme. Neuro Oncol. 2013;15:1366-78 pubmed 出版商

Sundlisaeter E, Edelmann R, Hol J, Sponheim J, Küchler A, WEISS M, et al. The alarmin IL-33 is a notch target in quiescent endothelial cells. Am J Pathol. 2012;181:1099-111 pubmed 出版商

Diaz Cuadros M, Wagner D, Budjan C, Hubaud A, Tarazona O, Donelly S, et al. In vitro characterization of the human segmentation clock. Nature. 2020;580:113-118 pubmed 出版商

Onodera Y, Teramura T, Takehara T, Itokazu M, Mori T, Fukuda K. Inflammation-associated miR-155 activates differentiation of muscular satellite cells. PLoS ONE. 2018;13:e0204860 pubmed 出版商

Wang Q, Yan R, Pinnell N, McCarter A, Oh Y, Liu Y, et al. Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development. Blood. 2018;: pubmed 出版商

Ikenoue T, Terakado Y, Zhu C, Liu X, Ohsugi T, Matsubara D, et al. Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation. Sci Rep. 2018;8:2021 pubmed 出版商

Zheng Y, Wang Z, Ding X, Zhang W, Li G, Liu L, et al. A novel Notch1 missense mutation (C1133Y) in the Abruptex domain exhibits enhanced proliferation and invasion in oral squamous cell carcinoma. Cancer Cell Int. 2018;18:6 pubmed 出版商

Mack J, Mosqueiro T, Archer B, Jones W, Sunshine H, Faas G, et al. NOTCH1 is a mechanosensor in adult arteries. Nat Commun. 2017;8:1620 pubmed 出版商

Court H, Ahearn I, Amoyel M, Bach E, Philips M. Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT. J Cell Biol. 2017;216:4165-4182 pubmed 出版商

Takeuchi H, Yu H, Hao H, Takeuchi M, Ito A, Li H, et al. O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking. J Biol Chem. 2017;292:15964-15973 pubmed 出版商

Ogura H, Nagatake Kobayashi Y, Adachi J, Tomonaga T, Fujita N, Katayama R. TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity. Sci Rep. 2017;7:5519 pubmed 出版商

Fujiki K, Inamura H, Miyayama T, Matsuoka M. Involvement of Notch1 signaling in malignant progression of A549 cells subjected to prolonged cadmium exposure. J Biol Chem. 2017;292:7942-7953 pubmed 出版商

Taniguchi K, Moroishi T, de Jong P, Krawczyk M, Grebbin B, Luo H, et al. YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis. Proc Natl Acad Sci U S A. 2017;114:1643-1648 pubmed 出版商

Britton G, Ambler R, Clark D, Hill E, Tunbridge H, McNally K, et al. PKC? links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton. elife. 2017;6: pubmed 出版商

Kikuchi H, Sakakibara Konishi J, Furuta M, Yokouchi H, Nishihara H, Yamazaki S, et al. Expression of Notch1 and Numb in small cell lung cancer. Oncotarget. 2017;8:10348-10358 pubmed 出版商

Zhou W, He Q, Zhang C, He X, Cui Z, Liu F, et al. BLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development. elife. 2016;5: pubmed 出版商

Chen Y, Liu Y, Wei H, Lv K, Fu P. Large intergenic non-coding RNA-ROR reverses gemcitabine-induced autophagy and apoptosis in breast cancer cells. Oncotarget. 2016;7:59604-59617 pubmed 出版商

Ezratty E, Pasolli H, Fuchs E. A Presenilin-2-ARF4 trafficking axis modulates Notch signaling during epidermal differentiation. J Cell Biol. 2016;214:89-101 pubmed 出版商

Huang W, Martin E, Burman B, Gonzalez M, Kleer C. The matricellular protein CCN6 (WISP3) decreases Notch1 and suppresses breast cancer initiating cells. Oncotarget. 2016;7:25180-93 pubmed 出版商

Faronato M, Nguyen V, Patten D, Lombardo Y, Steel J, Patel N, et al. DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyper-activation. Oncotarget. 2015;6:22467-79 pubmed

Hwang S, Palin A, Li L, Song K, Lee J, Herz J, et al. TCR ITAM multiplicity is required for the generation of follicular helper T-cells. Nat Commun. 2015;6:6982 pubmed 出版商

Otti G, Saleh L, Velicky P, Fiala C, Pollheimer J, Knöfler M. Notch2 controls prolactin and insulin-like growth factor binding protein-1 expression in decidualizing human stromal cells of early pregnancy. PLoS ONE. 2014;9:e112723 pubmed 出版商

Matulic M, Skelin J, Radić Kristo D, Kardum Skelin I, Grcevic D, Antica M. Notch affects the prodifferentiating effect of retinoic acid and PMA on leukemic cells. Cytometry A. 2015;87:129-36 pubmed 出版商

Fujiki K, Inamura H, Matsuoka M. Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells. Cell Death Dis. 2014;5:e1378 pubmed 出版商

Wolfe A, Singh K, Zhong Y, Drewe P, Rajasekhar V, Sanghvi V, et al. RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer. Nature. 2014;513:65-70 pubmed 出版商

Harjes U, Bridges E, McIntyre A, Fielding B, Harris A. Fatty acid-binding protein 4, a point of convergence for angiogenic and metabolic signaling pathways in endothelial cells. J Biol Chem. 2014;289:23168-76 pubmed 出版商

Lombardo Y, Faronato M, Filipovic A, Vircillo V, Magnani L, Coombes R. Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cells. Breast Cancer Res. 2014;16:R62 pubmed 出版商

Zhang S, Chung W, Wu G, Egan S, Xu K. Tumor-suppressive activity of Lunatic Fringe in prostate through differential modulation of Notch receptor activation. Neoplasia. 2014;16:158-67 pubmed 出版商

Hagenbeek T, Wu X, Choy L, Sanchez Irizarry C, Seshagiri S, Stinson J, et al. Murine Pten(-/-) T-ALL requires non-redundant PI3K/mTOR and DLL4/Notch1 signals for maintenance and ?c/TCR signals for thymic exit. Cancer Lett. 2014;346:237-48 pubmed 出版商

Liu J, Fan H, Ma Y, Liang D, Huang R, Wang J, et al. Notch1 is a 5-fluorouracil resistant and poor survival marker in human esophagus squamous cell carcinomas. PLoS ONE. 2013;8:e56141 pubmed 出版商

Chen S, Xu Y, Chen Y, Li X, Mou W, Wang L, et al. SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells. PLoS ONE. 2012;7:e36326 pubmed 出版商

Choi P, van Riggelen J, Gentles A, Bachireddy P, Rakhra K, Adam S, et al. Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction. Proc Natl Acad Sci U S A. 2011;108:17432-7 pubmed 出版商