产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
ALK(D5F3)XP®兔单克隆抗体
目录 :
3633
克隆性 :
单克隆
宿主 :
共轭标签 :
nonconjugated
克隆名称 :
D5F3
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
文章摘录数: 33
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 2a
Wang R, Deng X, Yoshioka Y, Vougiouklakis T, Park J, Suzuki T, et al. Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-small-cell lung cancer cells. Cancer Sci. 2017;108:1203-1209 pubmed 出版商
  • 免疫印迹; 人类; 图 s7
Morena D, Maestro N, Bersani F, Forni P, Lingua M, Foglizzo V, et al. Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes. elife. 2016;5: pubmed 出版商
Vaishnavi A, Schubert L, Rix U, Marek L, Le A, Keysar S, et al. EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases. Cancer Res. 2017;77:3551-3563 pubmed 出版商
Mattsson J, Brunnström H, Jabs V, Edlund K, Jirstrom K, Mindus S, et al. Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer. BMC Cancer. 2016;16:603 pubmed 出版商
Guan J, Umapathy G, Yamazaki Y, Wolfstetter G, Mendoza P, Pfeifer K, et al. FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase. elife. 2015;4:e09811 pubmed 出版商
Mitou G, Frentzel J, Desquesnes A, Le Gonidec S, Alsaati T, Beau I, et al. Targeting autophagy enhances the anti-tumoral action of crizotinib in ALK-positive anaplastic large cell lymphoma. Oncotarget. 2015;6:30149-64 pubmed 出版商
Iacono D, Chiari R, Metro G, Bennati C, Bellezza G, Cenci M, et al. Future options for ALK-positive non-small cell lung cancer. Lung Cancer. 2015;87:211-9 pubmed 出版商
Kotoula V, Bobos M, Vassilakopoulou M, Tsolaki E, Chrisafi S, Psyrri A, et al. Intact or broken-apart RNA: an alternative concept for ALK fusion screening in non-small cell lung cancer (NSCLC). Appl Immunohistochem Mol Morphol. 2015;23:60-70 pubmed 出版商
Doble B, Tan M, Harris A, Lorgelly P. Modeling companion diagnostics in economic evaluations of targeted oncology therapies: systematic review and methodological checklist. Expert Rev Mol Diagn. 2015;15:235-54 pubmed 出版商
Zhang K, Deng H, Cagle P. Utility of immunohistochemistry in the diagnosis of pleuropulmonary and mediastinal cancers: a review and update. Arch Pathol Lab Med. 2014;138:1611-28 pubmed 出版商
Marchetti A, Barberis M, Papotti M, Rossi G, Franco R, Malatesta S, et al. ALK rearrangement testing by FISH analysis in non-small-cell lung cancer patients: results of the first italian external quality assurance scheme. J Thorac Oncol. 2014;9:1470-6 pubmed 出版商
Cha Y, Lee J, Kim H, Lim S, Cho B, Lee C, et al. Screening of ROS1 rearrangements in lung adenocarcinoma by immunohistochemistry and comparison with ALK rearrangements. PLoS ONE. 2014;9:e103333 pubmed 出版商
Yang L, Li G, Zhao L, Pan F, Qiang J, Han S. Blocking the PI3K pathway enhances the efficacy of ALK-targeted therapy in EML4-ALK-positive nonsmall-cell lung cancer. Tumour Biol. 2014;35:9759-67 pubmed 出版商
Choi P, Meyerson M. Targeted genomic rearrangements using CRISPR/Cas technology. Nat Commun. 2014;5:3728 pubmed 出版商
Berghoff A, Birner P, Streubel B, Kenner L, Preusser M. ALK gene aberrations and the JUN/JUNB/PDGFR axis in metastatic NSCLC. APMIS. 2014;122:867-72 pubmed 出版商
Minca E, Lanigan C, Reynolds J, Wang Z, Ma P, Cicenia J, et al. ALK status testing in non-small-cell lung carcinoma by FISH on ThinPrep slides with cytology material. J Thorac Oncol. 2014;9:464-8 pubmed 出版商
Feng Y, Minca E, Lanigan C, Liu A, Zhang W, Yin L, et al. High MET receptor expression but not gene amplification in ALK 2p23 rearrangement positive non-small-cell lung cancer. J Thorac Oncol. 2014;9:646-53 pubmed 出版商
Yang J, Zhang X, Su J, Xu C, Zhou Q, Tian H, et al. Lung cancers with concomitant EGFR mutations and ALK rearrangements: diverse responses to EGFR-TKI and crizotinib in relation to diverse receptors phosphorylation. Clin Cancer Res. 2014;20:1383-92 pubmed 出版商
Shan L, Lian F, Guo L, Yang X, Ying J, Lin D. Combination of conventional immunohistochemistry and qRT-PCR to detect ALK rearrangement. Diagn Pathol. 2014;9:3 pubmed 出版商
Han X, Zhang N, Ma L, Lin D, Hao X, Liu Y, et al. Immunohistochemistry reliably detects ALK rearrangements in patients with advanced non-small-cell lung cancer. Virchows Arch. 2013;463:583-91 pubmed 出版商
Li Y, Pan Y, Wang R, Sun Y, Hu H, Shen X, et al. ALK-rearranged lung cancer in Chinese: a comprehensive assessment of clinicopathology, IHC, FISH and RT-PCR. PLoS ONE. 2013;8:e69016 pubmed 出版商
Ying J, Guo L, Qiu T, Shan L, Ling Y, Liu X, et al. Diagnostic value of a novel fully automated immunochemistry assay for detection of ALK rearrangement in primary lung adenocarcinoma. Ann Oncol. 2013;24:2589-93 pubmed 出版商
Niu H, Zhou Q, Wang F, Shao Q, Guan Y, Wen X, et al. Identification of anaplastic lymphoma kinase break points and oncogenic mutation profiles in acral/mucosal melanomas. Pigment Cell Melanoma Res. 2013;26:646-53 pubmed 出版商
Selinger C, Rogers T, Russell P, O Toole S, Yip P, Wright G, et al. Testing for ALK rearrangement in lung adenocarcinoma: a multicenter comparison of immunohistochemistry and fluorescent in situ hybridization. Mod Pathol. 2013;26:1545-53 pubmed 出版商
Zhang Y, Jin M, Li L, Zhao H, Zeng X, Jiang L, et al. Evaluation of ALK rearrangement in Chinese non-small cell lung cancer using FISH, immunohistochemistry, and real-time quantitative RT- PCR on paraffin-embedded tissues. PLoS ONE. 2013;8:e64821 pubmed 出版商
Roberts P. Clinical use of crizotinib for the treatment of non-small cell lung cancer. Biologics. 2013;7:91-101 pubmed 出版商
Nakamura H, Tsuta K, Yoshida A, Shibata T, Wakai S, Asamura H, et al. Aberrant anaplastic lymphoma kinase expression in high-grade pulmonary neuroendocrine carcinoma. J Clin Pathol. 2013;66:705-7 pubmed 出版商
Filtenborg Barnkob B, Bzorek M. Expression of anaplastic lymphoma kinase in Merkel cell carcinomas. Hum Pathol. 2013;44:1656-64 pubmed 出版商
Minca E, Portier B, Wang Z, Lanigan C, Farver C, Feng Y, et al. ALK status testing in non-small cell lung carcinoma: correlation between ultrasensitive IHC and FISH. J Mol Diagn. 2013;15:341-6 pubmed 出版商
Preusser M, Berghoff A, Ilhan Mutlu A, Magerle M, Dinhof C, Widhalm G, et al. ALK gene translocations and amplifications in brain metastases of non-small cell lung cancer. Lung Cancer. 2013;80:278-83 pubmed 出版商
Conklin C, Craddock K, Have C, Laskin J, Couture C, Ionescu D. Immunohistochemistry is a reliable screening tool for identification of ALK rearrangement in non-small-cell lung carcinoma and is antibody dependent. J Thorac Oncol. 2013;8:45-51 pubmed 出版商
Wang Z, Zhang X, Bai H, Zhao J, Zhuo M, An T, et al. EML4-ALK rearrangement and its clinical significance in Chinese patients with advanced non-small cell lung cancer. Oncology. 2012;83:248-56 pubmed 出版商
Rimkunas V, Crosby K, Li D, Hu Y, Kelly M, Gu T, et al. Analysis of receptor tyrosine kinase ROS1-positive tumors in non-small cell lung cancer: identification of a FIG-ROS1 fusion. Clin Cancer Res. 2012;18:4449-57 pubmed 出版商
产品信息
SKU号 :
3633P
产品名称 :
ALK(D5F3)XP®兔单克隆抗体
规格 :
40微升
Price-(USD) :
281美元
物种x :
H
应用 :
流式细胞仪
产品种类 :
RTK
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
220(ALK), 80(NPM-ALK), 117(EML4-ALK v1), 86(EML4-ALK v3)
宿主 :
靶标 :
ALK
最初蛋白 :
ALK
别名 :
ALK,ALK tyrosine kinase receptor,Anaplastic lymphoma kinase,CD246,CD246 antigen,NBLST3,TFG/ALK,anaplastic lymphoma receptor tyrosine kinase
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。