Dinger K, Kasper P, Hucklenbruch-Rother E, Vohlen C, Jobst E, Janoschek R, et al. Early-onset obesity dysregulates pulmonary adipocytokine/insulin signaling and induces asthma-like disease in mice. Sci Rep. 2016;6:24168 pubmed 出版商

Jiao K, Zeng G, Niu L, Yang H, Ren G, Xu X, et al. Activation of α2A-adrenergic signal transduction in chondrocytes promotes degenerative remodelling of temporomandibular joint. Sci Rep. 2016;6:30085 pubmed 出版商

Li Q, Guo Y, Chen F, Liu J, Jin P. Stromal cell-derived factor-1 promotes human adipose tissue-derived stem cell survival and chronic wound healing. Exp Ther Med. 2016;12:45-50 pubmed

Yang Y, Zhang Y, Iwamoto H, Hosaka K, Seki T, Andersson P, et al. Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism. Nat Commun. 2016;7:12680 pubmed 出版商

Velázquez R, Shaw D, Caccamo A, Oddo S. Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease. Mol Neurodegener. 2016;11:52 pubmed 出版商

Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed 出版商

Ma Y, Guo H, Zhang L, Tao L, Yin A, Liu Z, et al. Estrogen replacement therapy-induced neuroprotection against brain ischemia-reperfusion injury involves the activation of astrocytes via estrogen receptor β. Sci Rep. 2016;6:21467 pubmed 出版商

Casasola A, Scalzo D, Nandakumar V, Halow J, Recillas-Targa F, Groudine M, et al. Prelamin A processing, accumulation and distribution in normal cells and laminopathy disorders. Nucleus. 2016;7:84-102 pubmed 出版商

Murakami-Tonami Y, Ikeda H, Yamagishi R, Inayoshi M, Inagaki S, Kishida S, et al. SGO1 is involved in the DNA damage response in MYCN-amplified neuroblastoma cells. Sci Rep. 2016;6:31615 pubmed 出版商

Miao H, Ou J, Peng Y, Zhang X, Chen Y, Hao L, et al. Macrophage ABHD5 promotes colorectal cancer growth by suppressing spermidine production by SRM. Nat Commun. 2016;7:11716 pubmed 出版商

Fang J, Jia C, Zheng Z, Ye X, Wei B, Huang L, et al. Periprostatic implantation of neural differentiated mesenchymal stem cells restores cavernous nerve injury-mediated erectile dysfunction. Am J Transl Res. 2016;8:2549-61 pubmed

Yang Y, Andersson P, Hosaka K, Zhang Y, Cao R, Iwamoto H, et al. The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages. Nat Commun. 2016;7:11385 pubmed 出版商

Zhang J, Lachance V, Schaffner A, Li X, Fedick A, Kaye L, et al. A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects. PLoS Genet. 2016;12:e1005848 pubmed 出版商

Li J, Su Y, Wang H, Zhao Y, Liao X, Wang X, et al. Repeated Blockade of NMDA Receptors During Adolescence Impairs Reversal Learning and Disrupts GABAergic Interneurons in Rat Medial Prefrontal Cortex. Front Mol Neurosci. 2016;9:17 pubmed 出版商

Zhang H, Kang E, Wang Y, Yang C, Yu H, Wang Q, et al. Brain-specific Crmp2 deletion leads to neuronal development deficits and behavioural impairments in mice. Nat Commun. 2016;7: pubmed 出版商

Ortuno D, Carlisle H, Miller S. Does inactivation of USP14 enhance degradation of proteasomal substrates that are associated with neurodegenerative diseases?. F1000Res. 2016;5:137 pubmed 出版商

Sahu N, Stephan J, Cruz D, Merchant M, Haley B, Bourgon R, et al. Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs. Nat Commun. 2016;7:12351 pubmed 出版商

Dong Y, Bao C, Yu J, Liu X. Receptor-interacting protein kinase 3-mediated programmed cell necrosis in rats subjected to focal cerebral ischemia-reperfusion injury. Mol Med Rep. 2016;14:728-36 pubmed 出版商

Yu J, Berga S, Johnston-MacAnanny E, Sidell N, Bagchi I, Bagchi M, et al. Endometrial Stromal Decidualization Responds Reversibly to Hormone Stimulation and Withdrawal. Endocrinology. 2016;157:2432-46 pubmed 出版商

Lim S, Liu H, Madeira da Silva L, Arora R, Liu Z, Phillips J, et al. Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1α. Cancer Res. 2016;76:2231-42 pubmed 出版商

Mester T, Raychaudhuri N, Gillespie E, Chen H, Smith T, Douglas R. CD40 Expression in Fibrocytes Is Induced by TSH: Potential Synergistic Immune Activation. PLoS ONE. 2016;11:e0162994 pubmed 出版商

Franzese O, Palermo B, Di Donna C, Sperduti I, Ferraresi V, Stabile H, et al. Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS. Oncoimmunology. 2016;5:e1114203 pubmed 出版商

Mehrabian M, Brethour D, Williams D, Wang H, Arnould H, Schneider B, et al. Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue. PLoS ONE. 2016;11:e0156779 pubmed 出版商

Zhuang L, Yang Y, Ma X, Han B, Wang Z, Zhao Q, et al. MicroRNA-92b promotes hepatocellular carcinoma progression by targeting Smad7 and is mediated by long non-coding RNA XIST. Cell Death Dis. 2016;7:e2203 pubmed 出版商

Crauwels P, Bohn R, Thomas M, Gottwalt S, Jäckel F, Krämer S, et al. Apoptotic-like Leishmania exploit the host's autophagy machinery to reduce T-cell-mediated parasite elimination. Autophagy. 2015;11:285-97 pubmed 出版商

Moniz S, Bandarra D, Biddlestone J, Campbell K, Komander D, Bremm A, et al. Cezanne regulates E2F1-dependent HIF2α expression. J Cell Sci. 2015;128:3082-93 pubmed 出版商

Yan S, Xu Z, Lou F, Zhang L, Ke F, Bai J, et al. NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis. Nat Commun. 2015;6:7652 pubmed 出版商

Chan-Penebre E, Kuplast K, Majer C, Boriack-Sjodin P, Wigle T, Johnston L, et al. A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models. Nat Chem Biol. 2015;11:432-7 pubmed 出版商

Wu C, Niu L, Yan Z, Wang C, Liu N, Dai Y, et al. Pcdh11x Negatively Regulates Dendritic Branching. J Mol Neurosci. 2015;56:822-8 pubmed 出版商

Grice S, Sleigh J, Motley W, Liu J, Burgess R, Talbot K, et al. Dominant, toxic gain-of-function mutations in gars lead to non-cell autonomous neuropathology. Hum Mol Genet. 2015;24:4397-406 pubmed 出版商

Mir S, George N, Zahoor L, Harms R, Guinn Z, SARVETNICK N. Inhibition of autophagic turnover in β-cells by fatty acids and glucose leads to apoptotic cell death. J Biol Chem. 2015;290:6071-85 pubmed 出版商

Zucal C, D'Agostino V, Casini A, Mantelli B, Thongon N, Soncini D, et al. EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition. BMC Cancer. 2015;15:855 pubmed 出版商

Momeny M, Saunus J, Marturana F, McCart Reed A, Black D, Sala G, et al. Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines. Oncotarget. 2015;6:3932-46 pubmed

Meadows S, Cleaver O. Annexin A3 Regulates Early Blood Vessel Formation. PLoS ONE. 2015;10:e0132580 pubmed 出版商

Jin S, Liu Y, Deng S, Liao L, Lin T, Ning Q, et al. Neuroprotective effects of activated protein C on intrauterine inflammation-induced neonatal white matter injury are associated with the downregulation of fibrinogen-like protein 2/fibroleukin prothrombinase and the inhibition of pro-inflammatory cytokine. Int J Mol Med. 2015;35:1199-212 pubmed 出版商

Boros G, Miko E, Muramatsu H, Weissman D, Emri E, van der Horst G, et al. Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA. PLoS ONE. 2015;10:e0131141 pubmed 出版商

Zhan Z, Xie X, Cao H, Zhou X, Zhang X, Fan H, et al. Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination. Autophagy. 2014;10:257-68 pubmed 出版商

Chen H, Mester T, Raychaudhuri N, Kauh C, Gupta S, Smith T, et al. Teprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in fibrocytes. J Clin Endocrinol Metab. 2014;99:E1635-40 pubmed 出版商

Warren C, Griffin L, Little A, Huang I, Farzan M, Pyeon D. The antiviral restriction factors IFITM1, 2 and 3 do not inhibit infection of human papillomavirus, cytomegalovirus and adenovirus. PLoS ONE. 2014;9:e96579 pubmed 出版商

Mudie S, Bandarra D, Batie M, Biddlestone J, Moniz S, Ortmann B, et al. PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia. Cell Cycle. 2014;13:3878-91 pubmed 出版商

Hasanali Z, Epner E, Feith D, Loughran T, Sample C. Vorinostat downregulates CD30 and decreases brentuximab vedotin efficacy in human lymphocytes. Mol Cancer Ther. 2014;13:2784-92 pubmed 出版商

Guerrouahen B, Pasquier J, Kaoud N, Maleki M, Beauchamp M, Yasmeen A, et al. Akt-activated endothelium constitutes the niche for residual disease and resistance to bevacizumab in ovarian cancer. Mol Cancer Ther. 2014;13:3123-36 pubmed 出版商

Killinger B, Shah M, Moszczynska A. Co-administration of betulinic acid and methamphetamine causes toxicity to dopaminergic and serotonergic nerve terminals in the striatum of late adolescent rats. J Neurochem. 2014;128:764-75 pubmed 出版商

Naidoo N, Davis J, Zhu J, Yabumoto M, Singletary K, Brown M, et al. Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism. Aging Cell. 2014;13:131-41 pubmed 出版商

Kainulainen M, Habjan M, Hubel P, Busch L, Lau S, Colinge J, et al. Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH. J Virol. 2014;88:3464-73 pubmed 出版商

Gillespie E, Raychaudhuri N, Papageorgiou K, Atkins S, Lu Y, Charara L, et al. Interleukin-6 production in CD40-engaged fibrocytes in thyroid-associated ophthalmopathy: involvement of Akt and NF-κB. Invest Ophthalmol Vis Sci. 2012;53:7746-53 pubmed 出版商

Wen S, Jadhav K, Williamson D, Rideout T. Treadmill Exercise Training Modulates Hepatic Cholesterol Metabolism and Circulating PCSK9 Concentration in High-Fat-Fed Mice. J Lipids. 2013;2013:908048 pubmed 出版商

Yang R, Zhong L, Yang X, Jiang K, Li L, Song H, et al. Neutrophil elastase enhances the proliferation and decreases apoptosis of leukemia cells via activation of PI3K/Akt signaling. Mol Med Rep. 2016;13:4175-82 pubmed 出版商

Lin R, Yu K, Li X, Tao J, Lin Y, Zhao C, et al. Electroacupuncture ameliorates post-stroke learning and memory through minimizing ultrastructural brain damage and inhibiting the expression of MMP-2 and MMP-9 in cerebral ischemia-reperfusion injured rats. Mol Med Rep. 2016;14:225-33 pubmed 出版商

Wright D, Renoir T, Smith Z, Frazier A, Francis P, Thorburn D, et al. N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease. Transl Psychiatry. 2015;5:e492 pubmed 出版商

Hwang S, Disatnik M, Mochly-Rosen D. Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease. EMBO Mol Med. 2015;7:1307-26 pubmed 出版商

Wang H, Sharma L, Lu J, Finch P, Fletcher S, Prochownik E. Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion. Oncotarget. 2015;6:15857-70 pubmed

Levring T, Kongsbak M, Rode A, Woetmann A, Ødum N, Bonefeld C, et al. Human CD4+ T cells require exogenous cystine for glutathione and DNA synthesis. Oncotarget. 2015;6:21853-64 pubmed

Wang H, Teriete P, Hu A, Raveendra-Panickar D, Pendelton K, Lazo J, et al. Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids. Oncotarget. 2015;6:32380-95 pubmed 出版商

Hung M, Leonard J. Stabilization of exosome-targeting peptides via engineered glycosylation. J Biol Chem. 2015;290:8166-72 pubmed 出版商

Korhonova M, Doricakova A, Dvorak Z. Optical Isomers of Atorvastatin, Rosuvastatin and Fluvastatin Enantiospecifically Activate Pregnane X Receptor PXR and Induce CYP2A6, CYP2B6 and CYP3A4 in Human Hepatocytes. PLoS ONE. 2015;10:e0137720 pubmed 出版商

Fan C, Wang Y, Liu Z, Sun Y, Wang X, Wei G, et al. Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer. Int J Mol Med. 2015;36:204-14 pubmed 出版商

Li J, Lam M. Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. elife. 2015;4:e06434 pubmed 出版商

Fortin D, Tillo S, Yang G, Rah J, Melander J, Bai S, et al. Live imaging of endogenous PSD-95 using ENABLED: a conditional strategy to fluorescently label endogenous proteins. J Neurosci. 2014;34:16698-712 pubmed 出版商

Cai M, Liu P, Wei L, Wang J, Qi J, Feng S, et al. Atp6v1c1 may regulate filament actin arrangement in breast cancer cells. PLoS ONE. 2014;9:e84833 pubmed 出版商

Baxter P, Lin Q, Mao H, Kogiso M, Zhao X, Liu Z, et al. Silencing BMI1 eliminates tumor formation of pediatric glioma CD133+ cells not by affecting known targets but by down-regulating a novel set of core genes. Acta Neuropathol Commun. 2014;2:160 pubmed 出版商

Li M, Yang Y, He Z, Zhou Z, Yang T, Guo P, et al. MicroRNA-561 promotes acetaminophen-induced hepatotoxicity in HepG2 cells and primary human hepatocytes through downregulation of the nuclear receptor corepressor dosage-sensitive sex-reversal adrenal hypoplasia congenital critical region on the X chromos. Drug Metab Dispos. 2014;42:44-61 pubmed 出版商

Logan R, Kong A, Krise J. Time-dependent effects of hydrophobic amine-containing drugs on lysosome structure and biogenesis in cultured human fibroblasts. J Pharm Sci. 2014;103:3287-96 pubmed 出版商

Burcham G, Cresswell G, Snyder P, Chen L, Liu X, Crist S, et al. Impact of prostate inflammation on lesion development in the POET3(+)Pten(+/-) mouse model of prostate carcinogenesis. Am J Pathol. 2014;184:3176-91 pubmed 出版商

Zhou Q, Jiang L, Xu C, Luo D, Zeng C, Liu P, et al. Ginsenoside Rg1 inhibits platelet activation and arterial thrombosis. Thromb Res. 2014;133:57-65 pubmed 出版商

Gajdosechova L, Krskova K, Segarra A, Špolcová A, Suski M, Olszanecki R, et al. Hypooxytocinaemia in obese Zucker rats relates to oxytocin degradation in liver and adipose tissue. J Endocrinol. 2014;220:333-43 pubmed 出版商

Wang F, Awan U, Wang Y, Wang L, Qing H, Ma H, et al. Damage of neuroblastoma cell SH-SY5Y mediated by MPP+ inhibits proliferation of T-cell leukemia Jurkat by co-culture system. Int J Mol Sci. 2014;15:10738-50 pubmed 出版商

Torocsik D, Kovacs D, Camera E, Lovászi M, Cseri K, Nagy G, et al. Leptin promotes a proinflammatory lipid profile and induces inflammatory pathways in human SZ95 sebocytes. Br J Dermatol. 2014;171:1326-35 pubmed 出版商

Tarassishin L, Suh H, Lee S. Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway. J Neuroinflammation. 2011;8:187 pubmed 出版商

Lai Y, Cheng J, Cheng D, Feasel M, Beste K, Peng J, et al. SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells. BMC Cell Biol. 2011;12:50 pubmed 出版商

Tarassishin L, Loudig O, Bauman A, Shafit-Zagardo B, Suh H, Lee S. Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*. Glia. 2011;59:1911-22 pubmed 出版商

Srivastava A, Srivastava P, Al-Khedhairy A, Musarrat J, Shukla Y. Allethrin-induced genotoxicity and oxidative stress in Swiss albino mice. Mutat Res. 2012;747:22-8 pubmed 出版商

Balakrishnan B, Sen D, Hareendran S, Roshini V, David S, Srivastava A, et al. Activation of the cellular unfolded protein response by recombinant adeno-associated virus vectors. PLoS ONE. 2013;8:e53845 pubmed 出版商

Liao R, Jung J, Tchaicha J, Wilkerson M, Sivachenko A, Beauchamp E, et al. Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma. Cancer Res. 2013;73:5195-205 pubmed 出版商

Siegfried A, Berchtold S, Manncke B, Deuschle E, Reber J, Ott T, et al. IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS)-induced TNF-α secretion and LPS-induced endotoxin shock. J Immunol. 2013;191:3913-21 pubmed 出版商

Ueno T, Endo S, Saito R, Hirose M, Hirai S, Suzuki H, et al. The sirtuin inhibitor tenovin-6 upregulates death receptor 5 and enhances cytotoxic effects of 5-fluorouracil and oxaliplatin in colon cancer cells. Oncol Res. 2013;21:155-64 pubmed 出版商

Zheng Y, Zhang H, Zhang X, Feng D, Luo X, Zeng C, et al. MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia. Oncogene. 2012;31:80-92 pubmed 出版商

Hu H, Li Z, Zhu X, Lin R, Lin J, Peng J, et al. Gua Lou Gui Zhi decoction suppresses LPS-induced activation of the TLR4/NF-κB pathway in BV-2 murine microglial cells. Int J Mol Med. 2013;31:1327-32 pubmed 出版商

Logan R, Kong A, Krise J. Evaluating the roles of autophagy and lysosomal trafficking defects in intracellular distribution-based drug-drug interactions involving lysosomes. J Pharm Sci. 2013;102:4173-80 pubmed 出版商

Taghiabadi E, Imenshahidi M, Abnous K, Mosafa F, Sankian M, Memar B, et al. Protective Effect of Silymarin against Acrolein-Induced Cardiotoxicity in Mice. Evid Based Complement Alternat Med. 2012;2012:352091 pubmed 出版商

Bracarense A, Lucioli J, Grenier B, Drociunas Pacheco G, Moll W, Schatzmayr G, et al. Chronic ingestion of deoxynivalenol and fumonisin, alone or in interaction, induces morphological and immunological changes in the intestine of piglets. Br J Nutr. 2012;107:1776-86 pubmed 出版商