产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Phospho-Akt (Ser473) (736E11) Rabbit mAb
目录 :
3787S
规格 :
100微升
价格 :
274美元
克隆性 :
单克隆
宿主 :
抗原修饰 :
磷酸化
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, immunohistochemistry - free floating section
文章摘录数: 38
已发表的文献中的应用方法/种属/稀释度参考文献
  • 流式细胞仪; 小鼠; 图 2
Luo C, Liao W, Dadi S, Toure A, Li M. Graded Foxo1 activity in Treg cells differentiates tumour immunity from spontaneous autoimmunity. Nature. 2016;529:532-6 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5
Pan D, Jiang C, Ma Z, Blonska M, You M, Lin X. MALT1 is required for EGFR-induced NF-κB activation and contributes to EGFR-driven lung cancer progression. Oncogene. 2016;35:919-28 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2
Milan G, Romanello V, Pescatore F, Armani A, Paik J, Frasson L, et al. Regulation of autophagy and the ubiquitin-proteasome system by the FoxO transcriptional network during muscle atrophy. Nat Commun. 2015;6:6670 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Choi H, Zhang H, Park H, Choi K, Lee H, Agrawal V, et al. Yes-associated protein regulates endothelial cell contact-mediated expression of angiopoietin-2. Nat Commun. 2015;6:6943 pubmed 出版商
  • immunohistochemistry - free floating section; 小鼠; 1:300
  • 免疫印迹; 小鼠; 1:300
Philippou A, Minozzo F, Spinazzola J, Smith L, Lei H, Rassier D, et al. Masticatory muscles of mouse do not undergo atrophy in space. FASEB J. 2015;29:2769-79 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Qu D, Chen Y, Xu X, Zhang M, Zhang Y, Li S. Cbl-b-regulated extracellular signal-regulated kinase signaling is involved in the shikonin-induced apoptosis of lung cancer cells in vitro. Exp Ther Med. 2015;9:1265-1270 pubmed
  • 免疫印迹; 人类
Barber A, Castillo-Martin M, Bonal D, Jia A, Rybicki B, Christiano A, et al. PI3K/AKT pathway regulates E-cadherin and Desmoglein 2 in aggressive prostate cancer. Cancer Med. 2015;4:1258-71 pubmed 出版商
  • 免疫印迹; 人类
Hatfield I, Harvey I, Yates E, Redd J, Reiter L, Bridges D. The role of TORC1 in muscle development in Drosophila. Sci Rep. 2015;5:9676 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1 ug/ml; 表 1
Cookman C, Belcher S. Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Growth of Medulloblastoma. Endocrinology. 2015;156:2395-408 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Artero-Castro A, Pérez-Alea M, Feliciano A, Leal J, Genestar M, Castellvi J, et al. Disruption of the ribosomal P complex leads to stress-induced autophagy. Autophagy. 2015;11:1499-519 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Castillo-Lluva S, Hontecillas-Prieto L, Blanco-Gómez A, Del Mar Sáez-Freire M, García-Cenador B, García-Criado J, et al. A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development. Oncogene. 2015;34:4777-90 pubmed 出版商
  • 免疫组化; 小鼠; 1:50
Foth M, Ahmad I, van Rhijn B, van der Kwast T, Bergman A, King L, et al. Fibroblast growth factor receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation with Pten loss in mice. J Pathol. 2014;233:148-58 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫组化; 人类; 1:100
Peng W, Hu X, Yao L, Jiang Y, Shao Z. Elevated expression of Girdin in the nucleus indicates worse prognosis for patients with estrogen receptor-positive breast cancer. Ann Surg Oncol. 2014;21:S648-56 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Maurin H, Lechat B, Borghgraef P, Devijver H, Jaworski T, Van Leuven F. Terminal hypothermic Tau.P301L mice have increased Tau phosphorylation independently of glycogen synthase kinase 3α/β. Eur J Neurosci. 2014;40:2442-53 pubmed 出版商
  • 免疫印迹; 小鼠
Trotter J, Lee G, Kazdoba T, Crowell B, Domogauer J, Mahoney H, et al. Dab1 is required for synaptic plasticity and associative learning. J Neurosci. 2013;33:15652-68 pubmed 出版商
Beretti F, Manni P, Longo C, Argenziano G, Farnetani F, Cesinaro A, et al. CD271 is expressed in melanomas with more aggressive behaviour, with correlation of characteristic morphology by in vivo reflectance confocal microscopy. Br J Dermatol. 2015;172:662-8 pubmed 出版商
Pasiliao C, Chang C, Sutherland B, Valdez S, Schaeffer D, Yapp D, et al. The involvement of insulin-like growth factor 2 binding protein 3 (IMP3) in pancreatic cancer cell migration, invasion, and adhesion. BMC Cancer. 2015;15:266 pubmed 出版商
Carlino M, Fung C, Shahheydari H, Todd J, Boyd S, Irvine M, et al. Preexisting MEK1P124 mutations diminish response to BRAF inhibitors in metastatic melanoma patients. Clin Cancer Res. 2015;21:98-105 pubmed 出版商
Lokody I, Francis J, Gardiner J, Erler J, Swain A. Pten Regulates Epithelial Cytodifferentiation during Prostate Development. PLoS ONE. 2015;10:e0129470 pubmed 出版商
Singh S, Chand H, Gundavarapu S, Saeed A, Langley R, Tesfaigzi Y, et al. HIF-1α Plays a Critical Role in the Gestational Sidestream Smoke-Induced Bronchopulmonary Dysplasia in Mice. PLoS ONE. 2015;10:e0137757 pubmed 出版商
Pallangyo C, Ziegler P, Greten F. IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis. J Exp Med. 2015;212:2253-66 pubmed 出版商
Kuboki Y, Shimizu K, Hatori T, Yamamoto M, Shibata N, Shiratori K, et al. Molecular biomarkers for progression of intraductal papillary mucinous neoplasm of the pancreas. Pancreas. 2015;44:227-35 pubmed 出版商
Pickhard A, Gröber S, Haug A, Piontek G, Wirth M, Straßen U, et al. Survivin and pAkt as potential prognostic markers in squamous cell carcinoma of the head and neck. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014;117:733-42 pubmed 出版商
Liu Z, Chen X, Song H, Wang H, Zhang G, Wang H, et al. Snail regulated by PKC/GSK-3β pathway is crucial for EGF-induced epithelial-mesenchymal transition (EMT) of cancer cells. Cell Tissue Res. 2014;358:491-502 pubmed 出版商
Ohtsubo K, Yamada T, Zhao L, Jin T, Takeuchi S, Mouri H, et al. Expression of Akt kinase-interacting protein 1, a scaffold protein of the PI3K/PDK1/Akt pathway, in pancreatic cancer. Pancreas. 2014;43:1093-100 pubmed 出版商
Wang W, Li Q, Takeuchi S, Yamada T, Koizumi H, Nakamura T, et al. Met kinase inhibitor E7050 reverses three different mechanisms of hepatocyte growth factor-induced tyrosine kinase inhibitor resistance in EGFR mutant lung cancer. Clin Cancer Res. 2012;18:1663-71 pubmed 出版商
Takeuchi S, Wang W, Li Q, Yamada T, Kita K, Donev I, et al. Dual inhibition of Met kinase and angiogenesis to overcome HGF-induced EGFR-TKI resistance in EGFR mutant lung cancer. Am J Pathol. 2012;181:1034-43 pubmed 出版商
Subbarayan P, Sarkar M, Nagaraja Rao S, Philip S, Kumar P, Altman N, et al. Achyranthes aspera (Apamarg) leaf extract inhibits human pancreatic tumor growth in athymic mice by apoptosis. J Ethnopharmacol. 2012;142:523-30 pubmed 出版商
Leopoldino A, Squarize C, Garcia C, Almeida L, Pestana C, Sobral L, et al. SET protein accumulates in HNSCC and contributes to cell survival: antioxidant defense, Akt phosphorylation and AVOs acidification. Oral Oncol. 2012;48:1106-13 pubmed 出版商
Wang K, Cao F, Fang W, Hu Y, Chen Y, Ding H, et al. Activation of SNAT1/SLC38A1 in human breast cancer: correlation with p-Akt overexpression. BMC Cancer. 2013;13:343 pubmed 出版商
Iqbal J, Thike A, Cheok P, Tse G, Tan P. Insulin growth factor receptor-1 expression and loss of PTEN protein predict early recurrence in triple-negative breast cancer. Histopathology. 2012;61:652-9 pubmed 出版商
Yamaguchi H, Kuboki Y, Hatori T, Yamamoto M, Shimizu K, Shiratori K, et al. The discrete nature and distinguishing molecular features of pancreatic intraductal tubulopapillary neoplasms and intraductal papillary mucinous neoplasms of the gastric type, pyloric gland variant. J Pathol. 2013;231:335-41 pubmed 出版商
Chaux A, Brimo F, Gonzalez-Roibon N, Shah S, Schultz L, Rizk J, et al. Immunohistochemical evidence of dysregulation of the mammalian target of rapamycin pathway in primary and metastatic pheochromocytomas. Urology. 2012;80:736.e7-12 pubmed 出版商
Fernandes I, Pacheco T, Costa A, Santos A, Fernandes A, Santos M, et al. Prognostic significance of AKT/mTOR signaling in advanced neuroendocrine tumors treated with somatostatin analogs. Onco Targets Ther. 2012;5:409-16 pubmed 出版商
Yip P, Wong L, Sears T, Yáñez-Muñoz R, McMahon S. Cortical overexpression of neuronal calcium sensor-1 induces functional plasticity in spinal cord following unilateral pyramidal tract injury in rat. PLoS Biol. 2010;8:e1000399 pubmed 出版商
Oh M, Lee H, Yoo S, Xu X, Choi J, Kim Y, et al. Clinicopathological correlations of mTOR and pAkt expression in non-small cell lung cancer. Virchows Arch. 2012;460:601-9 pubmed 出版商
Kim K, Wilson S, Abayasiriwardana K, Collins R, Fjellbirkeland L, Xu Z, et al. A novel in vitro model of human mesothelioma for studying tumor biology and apoptotic resistance. Am J Respir Cell Mol Biol. 2005;33:541-8 pubmed
Ganly I, Ricarte Filho J, Eng S, Ghossein R, Morris L, Liang Y, et al. Genomic dissection of Hurthle cell carcinoma reveals a unique class of thyroid malignancy. J Clin Endocrinol Metab. 2013;98:E962-72 pubmed 出版商
产品信息
SKU号 :
3787S
产品名称 :
Phospho-Akt (Ser473) (736E11) Rabbit mAb
规格 :
100微升
Price-(USD) :
274美元
物种x :
H, M,(R)
应用 :
免疫组化(冷冻)
产品种类 :
PI3K / Akt Signaling
运输温度 :
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
60
宿主 :
靶标 :
Akt1(Ser473)磷酸盐/Akt2(Ser474)磷酸盐/Akt3(Ser472)磷酸盐
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。