| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
| Li L, Yan S, Zhang H, Zhang M, Huang G, Chen M. Interaction of hnRNP K with MAP 1B-LC1 promotes TGF-β1-mediated epithelial to mesenchymal transition in lung cancer cells. BMC Cancer. 2019;19:894 pubmed 出版商 |
- 免疫组化-石蜡切片; 小鼠; 1:100; 图 3b, 4e
- 免疫印迹; 人类; 1:1000; 图 3c
| Slocum E, Craig A, Villanueva A, Germain D. Parity predisposes breasts to the oncogenic action of PAPP-A and activation of the collagen receptor DDR2. Breast Cancer Res. 2019;21:56 pubmed 出版商 |
- 免疫印迹; 人类; 1:1000; 图 4a, 4b, 4c
| Asnaghi L, White D, Key N, Choi J, Mahale A, Alkatan H, et al. ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma. Oncogene. 2019;38:2056-2075 pubmed 出版商 |
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商 |
| Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, et al. The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries. Nat Commun. 2017;8:14797 pubmed 出版商 |
- reverse phase protein lysate microarray; 人类; 图 st6
| Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed 出版商 |
| Kim N, Cha Y, Lee J, Lee S, Yang J, Yun J, et al. Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress. Nat Commun. 2017;8:14374 pubmed 出版商 |
| He Y, Northey J, Pelletier A, Kos Z, Meunier L, Haibe Kains B, et al. The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer. Oncogene. 2017;36:3490-3503 pubmed 出版商 |
- 免疫沉淀; 人类; 图 1o
- 免疫印迹; 人类; 1:500; 图 1i
| Liu T, Yu J, Deng M, Yin Y, Zhang H, Luo K, et al. CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1. Nat Commun. 2017;8:13923 pubmed 出版商 |
| Lee Y, Kim S, Song S, Hong H, Lee Y, Oh B, et al. Crosstalk between CCL7 and CCR3 promotes metastasis of colon cancer cells via ERK-JNK signaling pathways. Oncotarget. 2016;7:36842-36853 pubmed 出版商 |
| Kourtidis A, Anastasiadis P. PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications. Cell Cycle. 2016;15:498-505 pubmed 出版商 |
- 免疫印迹基因敲除验证; 人类; 1:1000; 图 2
| Haraguchi M, Sato M, Ozawa M. CRISPR/Cas9n-Mediated Deletion of the Snail 1Gene (SNAI1) Reveals Its Role in Regulating Cell Morphology, Cell-Cell Interactions, and Gene Expression in Ovarian Cancer (RMG-1) Cells. PLoS ONE. 2015;10:e0132260 pubmed 出版商 |
| Azzi S, Gallerne C, Romei C, Le Coz V, Gangemi R, Khawam K, et al. Human Renal Normal, Tumoral, and Cancer Stem Cells Express Membrane-Bound Interleukin-15 Isoforms Displaying Different Functions. Neoplasia. 2015;17:509-17 pubmed 出版商 |
| Cicchini C, de Nonno V, Battistelli C, Cozzolino A, De Santis Puzzonia M, Ciafrè S, et al. Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29. Biochim Biophys Acta. 2015;1849:919-29 pubmed 出版商 |
| Izawa G, Kobayashi W, Haraguchi M, Sudo A, Ozawa M. The ectopic expression of Snail in MDBK cells does not induce epithelial-mesenchymal transition. Int J Mol Med. 2015;36:166-72 pubmed 出版商 |
| Perdigão Henriques R, Petrocca F, Altschuler G, Thomas M, Le M, Tan S, et al. miR-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 and Snail1 transcriptional repressor complexes. Oncogene. 2016;35:158-72 pubmed 出版商 |
| Liu Y, Han X, Gao B. Knockdown of S100A11 expression suppresses ovarian cancer cell growth and invasion. Exp Ther Med. 2015;9:1460-1464 pubmed |
| Hsiao S, Chen M, Chen C, Chien M, Hua K, Hsiao M, et al. The H3K9 Methyltransferase G9a Represses E-cadherin and is Associated with Myometrial Invasion in Endometrial Cancer. Ann Surg Oncol. 2015;22 Suppl 3:S1556-65 pubmed 出版商 |
- 染色质免疫沉淀
; 人类
- EMSA; 人类
- 免疫印迹; 人类
| Lee M, Kim S, Kim B, Won C, Nam S, Kang S, et al. Snail1 induced in breast cancer cells in 3D collagen I gel environment suppresses cortactin and impairs effective invadopodia formation. Biochim Biophys Acta. 2014;1843:2037-54 pubmed 出版商 |
| Xia Y, Chang T, Wang Y, Liu Y, Li W, Li M, et al. YAP promotes ovarian cancer cell tumorigenesis and is indicative of a poor prognosis for ovarian cancer patients. PLoS ONE. 2014;9:e91770 pubmed 出版商 |
| Chen Y, Huang W, Chang S, Chang K, Kao S, Lo J, et al. Enhanced filopodium formation and stem-like phenotypes in a novel metastatic head and neck cancer cell model. Oncol Rep. 2013;30:2829-37 pubmed 出版商 |
| Devine D, Rostas J, Metge B, Das S, Mulekar M, Tucker J, et al. Loss of N-Myc interactor promotes epithelial-mesenchymal transition by activation of TGF-?/SMAD signaling. Oncogene. 2014;33:2620-8 pubmed 出版商 |
| Chu I, Lai W, Aprelikova O, El Touny L, Kouros Mehr H, Green J. Expression of GATA3 in MDA-MB-231 triple-negative breast cancer cells induces a growth inhibitory response to TGFß. PLoS ONE. 2013;8:e61125 pubmed 出版商 |
| Yang J, Kim N, Yun J, Cho E, Cha Y, Cho S, et al. Snail augments fatty acid oxidation by suppression of mitochondrial ACC2 during cancer progression. Life Sci Alliance. 2020;3: pubmed 出版商 |
| Noce V, Battistelli C, Cozzolino A, Consalvi V, Cicchini C, Strippoli R, et al. YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation. Cell Death Dis. 2019;10:768 pubmed 出版商 |
| Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, et al. PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019;129:1129-1151 pubmed 出版商 |
| Hojo N, Huisken A, Wang H, Chirshev E, Kim N, Nguyen S, et al. Snail knockdown reverses stemness and inhibits tumour growth in ovarian cancer. Sci Rep. 2018;8:8704 pubmed 出版商 |
| Skrzypek K, Kusienicka A, Trzyna E, Szewczyk B, Ulman A, Konieczny P, et al. SNAIL is a key regulator of alveolar rhabdomyosarcoma tumor growth and differentiation through repression of MYF5 and MYOD function. Cell Death Dis. 2018;9:643 pubmed 出版商 |
| Wei Y, Kim T, Peng D, Duan D, Gibbons D, Yamauchi M, et al. Fibroblast-specific inhibition of TGF-?1 signaling attenuates lung and tumor fibrosis. J Clin Invest. 2017;127:3675-3688 pubmed 出版商 |
| Battistelli C, Cicchini C, Santangelo L, Tramontano A, Grassi L, Gonzalez F, et al. The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition. Oncogene. 2017;36:942-955 pubmed 出版商 |
| Xiong S, Klausen C, Cheng J, Leung P. Activin B promotes endometrial cancer cell migration by down-regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling. Oncotarget. 2016;7:40060-40072 pubmed 出版商 |
| Piotrowski Daspit A, Tien J, Nelson C. Interstitial fluid pressure regulates collective invasion in engineered human breast tumors via Snail, vimentin, and E-cadherin. Integr Biol (Camb). 2016;8:319-31 pubmed 出版商 |
| Asnaghi L, Gezgin G, Tripathy A, Handa J, Merbs S, van der Velden P, et al. EMT-associated factors promote invasive properties of uveal melanoma cells. Mol Vis. 2015;21:919-29 pubmed |
| Fisher M, Adhikary G, Xu W, Kerr C, Keillor J, Eckert R. Type II transglutaminase stimulates epidermal cancer stem cell epithelial-mesenchymal transition. Oncotarget. 2015;6:20525-39 pubmed |
| Qiu Y, Li W, Zhang H, Liu Y, Tian X, Fang W. P2X7 mediates ATP-driven invasiveness in prostate cancer cells. PLoS ONE. 2014;9:e114371 pubmed 出版商 |
| Kumar S, Kumar D, Raina K, Agarwal R, Agarwal C. Functional modification of adipocytes by grape seed extract impairs their pro-tumorigenic signaling on colon cancer stem cells and the daughter cancer cells. Oncotarget. 2014;5:10151-69 pubmed |
| Yen Y, Shiah S, Chu H, Hsu Y, Hsiao J, Chang J, et al. Reciprocal regulation of microRNA-99a and insulin-like growth factor I receptor signaling in oral squamous cell carcinoma cells. Mol Cancer. 2014;13:6 pubmed 出版商 |
| Chen Y, Pan H, Tseng H, Chu H, Hung Y, Yen Y, et al. Differentiated epithelial- and mesenchymal-like phenotypes in subcutaneous mouse xenografts using diffusion weighted-magnetic resonance imaging. Int J Mol Sci. 2013;14:21943-59 pubmed 出版商 |
| Lee S, Tsai C, Yu C, Chang Y. Elevated snail expression mediates tumor progression in areca quid chewing-associated oral squamous cell carcinoma via reactive oxygen species. PLoS ONE. 2013;8:e67985 pubmed 出版商 |
| Laird A, O Mahony F, Nanda J, Riddick A, O Donnell M, Harrison D, et al. Differential expression of prognostic proteomic markers in primary tumour, venous tumour thrombus and metastatic renal cell cancer tissue and correlation with patient outcome. PLoS ONE. 2013;8:e60483 pubmed 出版商 |
| Teixidó C, Mares R, Aracil M, Ramon Y Cajal S, Hernandez Losa J. Epithelial-mesenchymal transition markers and HER3 expression are predictors of elisidepsin treatment response in breast and pancreatic cancer cell lines. PLoS ONE. 2013;8:e53645 pubmed 出版商 |
| Lin Z, Chu H, Yen Y, Lewis B, Chen Y. Krüppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression. PLoS ONE. 2012;7:e43593 pubmed 出版商 |
| Park I, Son H, Che Z, Kim J. A novel gain-of-function mutation of TGF-? receptor II promotes cancer progression via delayed receptor internalization in oral squamous cell carcinoma. Cancer Lett. 2012;315:161-9 pubmed 出版商 |
