出版应用/物种/样本/稀释 | 参考文献 |
---|
| Zhou L, Shao C, Xie Y, Wang N, Xu S, Luo B, et al. Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination. elife. 2020;9: pubmed 出版商
|
| Li H, Lan J, Wang G, Guo K, Han C, Li X, et al. KDM4B facilitates colorectal cancer growth and glucose metabolism by stimulating TRAF6-mediated AKT activation. J Exp Clin Cancer Res. 2020;39:12 pubmed 出版商
|
| Weisell J, Ohukainen P, Näpänkangas J, Ohlmeier S, Bergmann U, Peltonen T, et al. Heat shock protein 90 is downregulated in calcific aortic valve disease. BMC Cardiovasc Disord. 2019;19:306 pubmed 出版商
|
- 免疫印迹; 小鼠; 图 7c
- 免疫印迹; 人类; 图 2b
| Wang W, Shen T, Dong B, Creighton C, Meng Y, Zhou W, et al. MAPK4 overexpression promotes tumor progression via noncanonical activation of AKT/mTOR signaling. J Clin Invest. 2019;: pubmed 出版商
|
| Bishnupuri K, Alvarado D, Khouri A, Shabsovich M, Chen B, Dieckgraefe B, et al. IDO1 and kynurenine pathway metabolites activate PI3K-Akt signaling in the neoplastic colon epithelium to promote cancer cell proliferation and inhibit apoptosis. Cancer Res. 2019;: pubmed 出版商
|
| Liu Z, Li H, He L, Xiang Y, Tian C, Li C, et al. Discovery of Small-Molecule Inhibitors of the HSP90-Calcineurin-NFAT Pathway against Glioblastoma. Cell Chem Biol. 2019;26:352-365.e7 pubmed 出版商
|
| Bitar M, Nader J, Al Ali W, Al Madhoun A, Arefanian H, Al Mulla F. Hydrogen Sulfide Donor NaHS Improves Metabolism and Reduces Muscle Atrophy in Type 2 Diabetes: Implication for Understanding Sarcopenic Pathophysiology. Oxid Med Cell Longev. 2018;2018:6825452 pubmed 出版商
|
| Tsutsumi R, Harizanova J, Stockert R, Schröder K, Bastiaens P, Neel B. Assay to visualize specific protein oxidation reveals spatio-temporal regulation of SHP2. Nat Commun. 2017;8:466 pubmed 出版商
|
| Zaytouni T, Tsai P, Hitchcock D, DuBois C, Freinkman E, Lin L, et al. Critical role for arginase 2 in obesity-associated pancreatic cancer. Nat Commun. 2017;8:242 pubmed 出版商
|
| Simond A, Rao T, Zuo D, Zhao J, Muller W. ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor. Oncogene. 2017;36:6059-6066 pubmed 出版商
|
| Li M, Cheng W, Luo J, Hu X, Nie T, Lai H, et al. Loss of selenocysteine insertion sequence binding protein 2 suppresses the proliferation, migration/invasion and hormone secretion of human trophoblast cells via the PI3K/Akt and ERK signaling pathway. Placenta. 2017;55:81-89 pubmed 出版商
|
| Liu S, Cheng C. Akt Signaling Is Sustained by a CD44 Splice Isoform-Mediated Positive Feedback Loop. Cancer Res. 2017;77:3791-3801 pubmed 出版商
|
| Wolfson R, Chantranupong L, Wyant G, Gu X, Orozco J, Shen K, et al. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. 2017;543:438-442 pubmed 出版商
|
| Tao C, Hsu W, Ma Y, Cheng S, Lee E. Epigenetic regulation of HDAC1 SUMOylation as an endogenous neuroprotection against Aβ toxicity in a mouse model of Alzheimer's disease. Cell Death Differ. 2017;24:597-614 pubmed 出版商
|
| Natarajan S, Muthukrishnan E, Khalimonchuk O, Mott J, Becker D. Evidence for Pipecolate Oxidase in Mediating Protection Against Hydrogen Peroxide Stress. J Cell Biochem. 2017;118:1678-1688 pubmed 出版商
|
| Cao J, Tyburczy M, Moss J, Darling T, Widlund H, Kwiatkowski D. Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation. J Clin Invest. 2017;127:349-364 pubmed 出版商
|
| Yang J, Savvatis K, Kang J, Fan P, Zhong H, Schwartz K, et al. Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment. Nat Commun. 2016;7:13710 pubmed 出版商
|
| Visuttijai K, Pettersson J, Mehrbani Azar Y, van den Bout I, Orndal C, Marcickiewicz J, et al. Lowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT. PLoS ONE. 2016;11:e0164063 pubmed 出版商
|
| Zavorka M, Connelly C, Grosely R, MacDonald R. Inhibition of insulin-like growth factor II (IGF-II)-dependent cell growth by multidentate pentamannosyl 6-phosphate-based ligands targeting the mannose 6-phosphate/IGF-II receptor. Oncotarget. 2016;7:62386-62410 pubmed 出版商
|
| Krepler C, Xiao M, Samanta M, Vultur A, Chen H, Brafford P, et al. Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma. Oncotarget. 2016;7:71211-71222 pubmed 出版商
|
| Kaneda M, Messer K, Ralainirina N, Li H, Leem C, Gorjestani S, et al. PI3Kγ is a molecular switch that controls immune suppression. Nature. 2016;539:437-442 pubmed 出版商
|
| Lai M, Gonzalez Martin A, Cooper A, Oda H, Jin H, Shepherd J, et al. Regulation of B-cell development and tolerance by different members of the miR-17∼92 family microRNAs. Nat Commun. 2016;7:12207 pubmed 出版商
|
| Coppo M, Chinenov Y, Sacta M, Rogatsky I. The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis. Nat Commun. 2016;7:12254 pubmed 出版商
|
| Jiao K, Zeng G, Niu L, Yang H, Ren G, Xu X, et al. Activation of ?2A-adrenergic signal transduction in chondrocytes promotes degenerative remodelling of temporomandibular joint. Sci Rep. 2016;6:30085 pubmed 出版商
|
| Oliveira A, Gomes Marcondes M. Metformin treatment modulates the tumour-induced wasting effects in muscle protein metabolism minimising the cachexia in tumour-bearing rats. BMC Cancer. 2016;16:418 pubmed 出版商
|
| Barquilla A, Lamberto I, Noberini R, Heynen Genel S, Brill L, Pasquale E. Protein kinase A can block EphA2 receptor-mediated cell repulsion by increasing EphA2 S897 phosphorylation. Mol Biol Cell. 2016;27:2757-70 pubmed 出版商
|
| Zhao W, Li A, Feng X, Hou T, Liu K, Liu B, et al. Metformin and resveratrol ameliorate muscle insulin resistance through preventing lipolysis and inflammation in hypoxic adipose tissue. Cell Signal. 2016;28:1401-11 pubmed 出版商
|
| Xu Y, Liu J, He M, Liu R, Belegu V, Dai P, et al. Mechanisms of PDGF siRNA-mediated inhibition of bone cancer pain in the spinal cord. Sci Rep. 2016;6:27512 pubmed 出版商
|
- 免疫组化; 大鼠; 图 7a
- 免疫印迹; 大鼠; 1:1000; 图 s2d
| Fernandez Monreal M, Sánchez Castillo C, Esteban J. APPL1 gates long-term potentiation through its plekstrin homology domain. J Cell Sci. 2016;129:2793-803 pubmed 出版商
|
| Puchert M, Adams V, Linke A, Engele J. Evidence for the involvement of the CXCL12 system in the adaptation of skeletal muscles to physical exercise. Cell Signal. 2016;28:1205-15 pubmed 出版商
|
| Cui J, Zhang F, Wang Y, Liu J, Ming X, Hou J, et al. Macrophage migration inhibitory factor promotes cardiac stem cell proliferation and endothelial differentiation through the activation of the PI3K/Akt/mTOR and AMPK pathways. Int J Mol Med. 2016;37:1299-309 pubmed 出版商
|
| Koyani C, Kitz K, Rossmann C, Bernhart E, Huber E, Trummer C, et al. Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death. Biochem Pharmacol. 2016;104:29-41 pubmed 出版商
|
| Ito T, Itakura J, Takahashi S, Sato M, Mino M, Fushimi S, et al. Sprouty-Related Ena/Vasodilator-Stimulated Phosphoprotein Homology 1-Domain-Containing Protein-2 Critically Regulates Influenza A Virus-Induced Pneumonia. Crit Care Med. 2016;44:e530-43 pubmed 出版商
|
| Amato K, Wang S, Tan L, Hastings A, Song W, Lovly C, et al. EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer. Cancer Res. 2016;76:305-18 pubmed 出版商
|
| Carroll B, Maetzel D, Maddocks O, Otten G, Ratcliff M, Smith G, et al. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity. elife. 2016;5: pubmed 出版商
|
| Wang X, Tang Z, Yu D, Cui S, Jiang Y, Zhang Q, et al. Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma. Oncotarget. 2016;7:8823-38 pubmed 出版商
|
| Ho N, Morrison J, Silva A, Coomber B. The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression. Biosci Rep. 2016;36:e00299 pubmed 出版商
|
| Lagarrigue S, Lopez Mejia I, Denechaud P, Escoté X, Castillo Armengol J, Jimenez V, et al. CDK4 is an essential insulin effector in adipocytes. J Clin Invest. 2016;126:335-48 pubmed 出版商
|
| Messaoudi S, He Y, Gutsol A, Wight A, Hébert R, Vilmundarson R, et al. Endothelial Gata5 transcription factor regulates blood pressure. Nat Commun. 2015;6:8835 pubmed 出版商
|
| Green A, Maciel T, Hospital M, Yin C, Mazed F, Townsend E, et al. Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia. Sci Adv. 2015;1:e1500221 pubmed 出版商
|
| Momcilovic M, McMickle R, Abt E, Seki A, Simko S, Magyar C, et al. Heightening Energetic Stress Selectively Targets LKB1-Deficient Non-Small Cell Lung Cancers. Cancer Res. 2015;75:4910-22 pubmed 出版商
|
| Hukelmann J, Anderson K, Sinclair L, Grzes K, Murillo A, Hawkins P, et al. The cytotoxic T cell proteome and its shaping by the kinase mTOR. Nat Immunol. 2016;17:104-12 pubmed 出版商
|
| Lu R, Herrera B, Eshleman H, Fu Y, Bloom A, Li Z, et al. Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation. PLoS Pathog. 2015;11:e1005200 pubmed 出版商
|
| Nishimoto S, Tanaka H, Okamoto M, Okada K, Murase T, Yoshikawa H. Methylcobalamin promotes the differentiation of Schwann cells and remyelination in lysophosphatidylcholine-induced demyelination of the rat sciatic nerve. Front Cell Neurosci. 2015;9:298 pubmed 出版商
|
- 免疫印迹; 人类; 1:2000; 图 1c
- 免疫印迹; 小鼠; 图 1b
| Lee M, Jeong M, Lee H, Han H, Ko A, Hewitt S, et al. PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis. Nat Commun. 2015;6:7769 pubmed 出版商
|
| Urban B, Collard T, Eagle C, Southern S, Greenhough A, Hamdollah Zadeh M, et al. BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling. Gut. 2016;65:1151-64 pubmed 出版商
|
| Hsueh Y, Chen H, Wu S, Wang T, Chen J, Ma D. Lysophosphatidic acid induces YAP-promoted proliferation of human corneal endothelial cells via PI3K and ROCK pathways. Mol Ther Methods Clin Dev. 2015;2:15014 pubmed 出版商
|
| Liu H, Du L, Wang R, Wei C, Liu B, Zhu L, et al. High frequency of loss of PTEN expression in human solid salivary adenoid cystic carcinoma and its implication for targeted therapy. Oncotarget. 2015;6:11477-91 pubmed
|
| Bawadekar M, de Andrea M, Lo Cigno I, Baldanzi G, Caneparo V, Graziani A, et al. The Extracellular IFI16 Protein Propagates Inflammation in Endothelial Cells Via p38 MAPK and NF-κB p65 Activation. J Interferon Cytokine Res. 2015;35:441-53 pubmed 出版商
|
| Kondapalli K, Llongueras J, Capilla González V, Prasad H, Hack A, Smith C, et al. A leak pathway for luminal protons in endosomes drives oncogenic signalling in glioblastoma. Nat Commun. 2015;6:6289 pubmed 出版商
|
| Bai M, Yuan M, Liao H, Chen J, Xie B, Yan D, et al. OCT4 pseudogene 5 upregulates OCT4 expression to promote proliferation by competing with miR-145 in endometrial carcinoma. Oncol Rep. 2015;33:1745-52 pubmed 出版商
|
- 免疫印迹; 人类; 图 9
- 免疫印迹; 小鼠; 图 2
| Wang S, Amato K, Song W, Youngblood V, Lee K, Boothby M, et al. Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways. Mol Cell Biol. 2015;35:1299-313 pubmed 出版商
|
| Cheng Y, Chen P, Chiang H, Suen C, Hwang M, Lin T, et al. Candidate tumor suppressor B-cell translocation gene 3 impedes neoplastic progression by suppression of AKT. Cell Death Dis. 2015;6:e1584 pubmed 出版商
|
| Zheng H, Fu J, Xue P, Zhao R, Dong J, Liu D, et al. CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion. Antioxid Redox Signal. 2015;22:819-31 pubmed 出版商
|
| Chen C, Hung T, Lee C, Wang L, Wu C, Ke C, et al. Berberine protects against neuronal damage via suppression of glia-mediated inflammation in traumatic brain injury. PLoS ONE. 2014;9:e115694 pubmed 出版商
|
| Isoyama S, Kajiwara G, Tamaki N, Okamura M, Yoshimi H, Nakamura N, et al. Basal expression of insulin-like growth factor 1 receptor determines intrinsic resistance of cancer cells to a phosphatidylinositol 3-kinase inhibitor ZSTK474. Cancer Sci. 2015;106:171-8 pubmed 出版商
|
| Wu C, Hung T, Chen C, Ke C, Lee C, Wang P, et al. Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling. PLoS ONE. 2014;9:e113397 pubmed 出版商
|
| Qin J, Rajaratnam R, Feng L, Salami J, Barber Rotenberg J, Domsic J, et al. Development of organometallic S6K1 inhibitors. J Med Chem. 2015;58:305-14 pubmed 出版商
|
- 免疫印迹; 小鼠; 图 6
- 免疫印迹; 人类; 图 1
| Badolia R, Manne B, Dangelmaier C, Chernoff J, Kunapuli S. Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets. Blood. 2015;125:175-84 pubmed 出版商
|
| Wang Y, Yang R, Gu J, Yin X, Jin N, Xie S, et al. Cross talk between PI3K-AKT-GSK-3β and PP2A pathways determines tau hyperphosphorylation. Neurobiol Aging. 2015;36:188-200 pubmed 出版商
|
| Ritchie I, Wright D, Dyck D. Adiponectin is not required for exercise training-induced improvements in glucose and insulin tolerance in mice. Physiol Rep. 2014;2: pubmed 出版商
|
| Hu J, Cheng Y, Li Y, Jin Z, Pan Y, Liu G, et al. microRNA-128 plays a critical role in human non-small cell lung cancer tumourigenesis, angiogenesis and lymphangiogenesis by directly targeting vascular endothelial growth factor-C. Eur J Cancer. 2014;50:2336-50 pubmed 出版商
|
| Garimella S, Gehlhaus K, Dine J, Pitt J, Grandin M, Chakka S, et al. Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening. Breast Cancer Res. 2014;16:R41 pubmed 出版商
|
| Yu P, Laird A, Du X, Wu J, Won K, Yamaguchi K, et al. Characterization of the activity of the PI3K/mTOR inhibitor XL765 (SAR245409) in tumor models with diverse genetic alterations affecting the PI3K pathway. Mol Cancer Ther. 2014;13:1078-91 pubmed 出版商
|
| Zemljic Harpf A, Godoy J, Platoshyn O, Asfaw E, Busija A, Domenighetti A, et al. Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes. J Cell Sci. 2014;127:1104-16 pubmed 出版商
|
| Ziegler A, Chidambaram S, Forbes B, Wood T, Levison S. Insulin-like growth factor-II (IGF-II) and IGF-II analogs with enhanced insulin receptor-a binding affinity promote neural stem cell expansion. J Biol Chem. 2014;289:4626-33 pubmed 出版商
|
| Borghgraef P, Menuet C, Theunis C, Louis J, Devijver H, Maurin H, et al. Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice. PLoS ONE. 2013;8:e84442 pubmed 出版商
|
| Domingues N, Pelletier J, Ostenson C, Castro M. Therapeutic properties of VO(dmpp)2 as assessed by in vitro and in vivo studies in type 2 diabetic GK rats. J Inorg Biochem. 2014;131:115-22 pubmed 出版商
|
| Hernandez A, Colvin E, Chen Y, Geiss S, Eller L, Fueger P. Upregulation of p21 activates the intrinsic apoptotic pathway in ?-cells. Am J Physiol Endocrinol Metab. 2013;304:E1281-90 pubmed 出版商
|
| Fan C, Lum M, Xu C, Black J, Wang X. Ubiquitin-dependent regulation of phospho-AKT dynamics by the ubiquitin E3 ligase, NEDD4-1, in the insulin-like growth factor-1 response. J Biol Chem. 2013;288:1674-84 pubmed 出版商
|
| Rieger J, Lemke D, Maurer G, Weiler M, Frank B, Tabatabai G, et al. Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL. J Neurochem. 2008;106:2436-48 pubmed 出版商
|
| Heras Martínez G, Calleja V, Bailly R, Dessolin J, Larijani B, Requejo Isidro J. A Complex Interplay of Anionic Phospholipid Binding Regulates 3'-Phosphoinositide-Dependent-Kinase-1 Homodimer Activation. Sci Rep. 2019;9:14527 pubmed 出版商
|
| Morgan E, Macdonald A. Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1-NFκB-IL-6 signalling axis. PLoS Pathog. 2019;15:e1007835 pubmed 出版商
|
| Brown E, Lautz J, Davis T, Gniffke E, VanSchoiack A, Neier S, et al. Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models. Mol Autism. 2018;9:48 pubmed 出版商
|
| Peruchetti D, Silva Aguiar R, Siqueira G, Dias W, Caruso Neves C. High glucose reduces megalin-mediated albumin endocytosis in renal proximal tubule cells through protein kinase B O-GlcNAcylation. J Biol Chem. 2018;293:11388-11400 pubmed 出版商
|
| Olona A, Terra X, Ko J, Grau Bové C, Pinent M, Ardevol A, et al. Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis. Mol Metab. 2018;11:18-32 pubmed 出版商
|
| Beadnell T, Nassar K, Rose M, Clark E, Danysh B, Hofmann M, et al. Src-mediated regulation of the PI3K pathway in advanced papillary and anaplastic thyroid cancer. Oncogenesis. 2018;7:23 pubmed 出版商
|
| Zhou X, Dong S, Liu Z, Liu S, Zhang C, Liang X. Regulation of gammaherpesvirus lytic replication by endoplasmic reticulum stress-induced transcription factors ATF4 and CHOP. J Biol Chem. 2018;293:2801-2814 pubmed 出版商
|
| Landgraf K, Schuster S, Meusel A, Garten A, Riemer T, Schleinitz D, et al. Short-term overfeeding of zebrafish with normal or high-fat diet as a model for the development of metabolically healthy versus unhealthy obesity. BMC Physiol. 2017;17:4 pubmed 出版商
|
| Rogel A, Willoughby J, Buchan S, Leonard H, Thirdborough S, Al Shamkhani A. Akt signaling is critical for memory CD8+ T-cell development and tumor immune surveillance. Proc Natl Acad Sci U S A. 2017;114:E1178-E1187 pubmed 出版商
|
| Kondratiuk I, ÅÄ™ski S, UrbaÅ„ska M, Biecek P, Devijver H, Lechat B, et al. GSK-3β and MMP-9 Cooperate in the Control of Dendritic Spine Morphology. Mol Neurobiol. 2017;54:200-211 pubmed 出版商
|
| Egholm C, Khammy M, Dalsgaard T, Mazur A, Tritsaris K, Hansen A, et al. GLP-1 inhibits VEGFA-mediated signaling in isolated human endothelial cells and VEGFA-induced dilation of rat mesenteric arteries. Am J Physiol Heart Circ Physiol. 2016;311:H1214-H1224 pubmed 出版商
|
| Konishi H, Fujiya M, Tanaka H, Ueno N, Moriichi K, Sasajima J, et al. Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis. Nat Commun. 2016;7:12365 pubmed 出版商
|
| Coppock J, Vermeer P, Vermeer D, Lee K, Miskimins W, Spanos W, et al. mTOR inhibition as an adjuvant therapy in a metastatic model of HPV+ HNSCC. Oncotarget. 2016;7:24228-41 pubmed 出版商
|
| Pott G, Tsurudome M, Bamfo N, Goalstone M. ERK2 and Akt are negative regulators of insulin and Tumor Necrosis Factor-α stimulated VCAM-1 expression in rat aorta endothelial cells. J Inflamm (Lond). 2016;13:6 pubmed 出版商
|
| Chen Z, Canet M, Sheng L, Jiang L, Xiong Y, Yin L, et al. Hepatocyte TRAF3 promotes insulin resistance and type 2 diabetes in mice with obesity. Mol Metab. 2015;4:951-60 pubmed 出版商
|
| Beaton N, Rudigier C, Moest H, Müller S, Mrosek N, Röder E, et al. TUSC5 regulates insulin-mediated adipose tissue glucose uptake by modulation of GLUT4 recycling. Mol Metab. 2015;4:795-810 pubmed 出版商
|
| Huber R, Lucas J, Gomez Sarosi L, Coleman I, Zhao S, Coleman R, et al. DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance. Oncotarget. 2015;6:2134-47 pubmed
|
| Verbeke S, Richard E, Monceau E, Schmidt X, Rousseau B, Velasco V, et al. Humanization of the mouse mammary gland by replacement of the luminal layer with genetically engineered preneoplastic human cells. Breast Cancer Res. 2014;16:504 pubmed 出版商
|
| Qiu Y, Li W, Zhang H, Liu Y, Tian X, Fang W. P2X7 mediates ATP-driven invasiveness in prostate cancer cells. PLoS ONE. 2014;9:e114371 pubmed 出版商
|
| Kaihara K, Dickson L, Ellenbroek J, Orr C, Layden B, Wicksteed B. PKA Enhances the Acute Insulin Response Leading to the Restoration of Glucose Control. Diabetes. 2015;64:1688-97 pubmed 出版商
|
| Knievel J, Schulz W, Greife A, Hader C, Lübke T, Schmitz I, et al. Multiple mechanisms mediate resistance to sorafenib in urothelial cancer. Int J Mol Sci. 2014;15:20500-17 pubmed 出版商
|
| Xiao N, Eto D, Elly C, Peng G, Crotty S, Liu Y. The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells. Nat Immunol. 2014;15:657-66 pubmed 出版商
|
| Yu Q, Wu H, Huang X, Shen H, Shu Y, Zhang B, et al. MiR-1 targets PIK3CA and inhibits tumorigenic properties of A549 cells. Biomed Pharmacother. 2014;68:155-61 pubmed 出版商
|
| Sun Q, Mao S, Li H, Zen K, Zhang C, Li L. Role of miR-17 family in the negative feedback loop of bone morphogenetic protein signaling in neuron. PLoS ONE. 2013;8:e83067 pubmed 出版商
|
| Broholm C, Mathur N, Hvid T, Grøndahl T, Frøsig C, Pedersen B, et al. Insulin signaling in skeletal muscle of HIV-infected patients in response to endurance and strength training. Physiol Rep. 2013;1:e00060 pubmed 出版商
|
| Yue X, Hariri D, Caballero B, Zhang S, Bartlett M, Kaut O, et al. Comparative study of the neurotrophic effects elicited by VEGF-B and GDNF in preclinical in vivo models of Parkinson's disease. Neuroscience. 2014;258:385-400 pubmed 出版商
|
| Nakamura T, Yasuda S, Nagai H, Koinuma S, Morishita S, Goto A, et al. Longest neurite-specific activation of Rap1B in hippocampal neurons contributes to polarity formation through RalA and Nore1A in addition to PI3-kinase. Genes Cells. 2013;18:1020-31 pubmed 出版商
|
| Nawa M, Matsuoka M. KCTD20, a relative of BTBD10, is a positive regulator of Akt. BMC Biochem. 2013;14:27 pubmed 出版商
|
| Li J, Huang J, Jeong J, Park S, Wei R, Peng J, et al. Selective TBK1/IKKi dual inhibitors with anticancer potency. Int J Cancer. 2014;134:1972-80 pubmed 出版商
|
| Baptista I, Silva W, Artioli G, Guilherme J, Leal M, Aoki M, et al. Leucine and HMB differentially modulate proteasome system in skeletal muscle under different sarcopenic conditions. PLoS ONE. 2013;8:e76752 pubmed 出版商
|
| Niedan S, Kauer M, Aryee D, Kofler R, Schwentner R, Meier A, et al. Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma. Oncogene. 2014;33:3927-38 pubmed 出版商
|
| Sitnick M, Basantani M, Cai L, Schoiswohl G, Yazbeck C, Distefano G, et al. Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. Diabetes. 2013;62:3350-61 pubmed 出版商
|
| Liao R, Jung J, Tchaicha J, Wilkerson M, Sivachenko A, Beauchamp E, et al. Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma. Cancer Res. 2013;73:5195-205 pubmed 出版商
|
| Tsukamoto T, Hama S, Kogure K, Tsuchiya H. Selenate induces epithelial-mesenchymal transition in a colorectal carcinoma cell line by AKT activation. Exp Cell Res. 2013;319:1913-21 pubmed 出版商
|
| Nori S, Rocco M, Florenzano F, Ciotti M, Aloe L, Manni L. Increased nerve growth factor signaling in sensory neurons of early diabetic rats is corrected by electroacupuncture. Evid Based Complement Alternat Med. 2013;2013:652735 pubmed 出版商
|
| Zhang H, Yea K, Xie J, Ruiz D, Wilson I, Lerner R. Selecting agonists from single cells infected with combinatorial antibody libraries. Chem Biol. 2013;20:734-41 pubmed 出版商
|
| Ludyga N, Englert S, Pflieger K, Rauser S, Braselmann H, Walch A, et al. The impact of cysteine-rich intestinal protein 1 (CRIP1) in human breast cancer. Mol Cancer. 2013;12:28 pubmed 出版商
|
| Uto Konomi A, McKibben B, Wirtz J, Sato Y, Takano A, Nanki T, et al. CXCR7 agonists inhibit the function of CXCL12 by down-regulation of CXCR4. Biochem Biophys Res Commun. 2013;431:772-6 pubmed 出版商
|
| Meyer R, D Alessandro L, Kar S, Kramer B, She B, Kaschek D, et al. Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration. Front Physiol. 2012;3:451 pubmed 出版商
|
| Choi J, Wu W, Muchir A, Iwata S, Homma S, Worman H. Dual specificity phosphatase 4 mediates cardiomyopathy caused by lamin A/C (LMNA) gene mutation. J Biol Chem. 2012;287:40513-24 pubmed 出版商
|
| Chen S, Tsai H, Hung T, Chen C, Lee C, Wu C, et al. Salidroside improves behavioral and histological outcomes and reduces apoptosis via PI3K/Akt signaling after experimental traumatic brain injury. PLoS ONE. 2012;7:e45763 pubmed 出版商
|
| Syed F, Sherris D, Paus R, Varmeh S, Singh S, Pandolfi P, et al. Keloid disease can be inhibited by antagonizing excessive mTOR signaling with a novel dual TORC1/2 inhibitor. Am J Pathol. 2012;181:1642-58 pubmed 出版商
|
| Schaff M, Receveur N, Bourdon C, Ohlmann P, Lanza F, Gachet C, et al. ?-arrestin-1 participates in thrombosis and regulates integrin aIIb?3 signalling without affecting P2Y receptors desensitisation and function. Thromb Haemost. 2012;107:735-48 pubmed 出版商
|
| Yip W, Seow H. Activation of phosphatidylinositol 3-kinase/Akt signaling by EGF downregulates membranous E-cadherin and ?-catenin and enhances invasion in nasopharyngeal carcinoma cells. Cancer Lett. 2012;318:162-72 pubmed 出版商
|
| Sykes S, Lane S, Bullinger L, Kalaitzidis D, Yusuf R, Saez B, et al. AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias. Cell. 2011;146:697-708 pubmed 出版商
|
| Rohani M, DiJulio D, An J, Hacker B, Dale B, Chung W. PAR1- and PAR2-induced innate immune markers are negatively regulated by PI3K/Akt signaling pathway in oral keratinocytes. BMC Immunol. 2010;11:53 pubmed 出版商
|