产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Phospho-Akt (Ser473) (D9E) XP® Rabbit mAb (Alexa Fluor® 647 Conjugate)
目录 :
4075
克隆性 :
单克隆
宿主 :
共轭标签 :
AF647
抗原修饰 :
磷酸化
克隆名称 :
D9E
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片
文章摘录数: 16
出版应用/物种/样品/稀释参考文献
  • 流式细胞仪; 小鼠; 图 5e
Hwang I, Park C, Harrison K, Kehrl J. Normal Thymocyte Egress, T Cell Trafficking, and CD4+ T Cell Homeostasis Require Interactions between RGS Proteins and Gαi2. J Immunol. 2017;198:2721-2734 pubmed 出版商
  • 流式细胞仪; 人类; 图 s5
Gusscott S, Jenkins C, Lam S, Giambra V, Pollak M, Weng A. IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias. PLoS ONE. 2016;11:e0161158 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Ma T, Fan B, Zhang C, Zhao H, Han C, Gao C, et al. Metabonomics applied in exploring the antitumour mechanism of physapubenolide on hepatocellular carcinoma cells by targeting glycolysis through the Akt-p53 pathway. Sci Rep. 2016;6:29926 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Apostolidis S, Rodríguez Rodríguez N, Suárez Fueyo A, Dioufa N, Ozcan E, Crispín J, et al. Phosphatase PP2A is requisite for the function of regulatory T cells. Nat Immunol. 2016;17:556-64 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Kral J, Kuttke M, Schrottmaier W, Birnecker B, Warszawska J, Wernig C, et al. Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways. Sci Rep. 2016;6:23034 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Egawa H, Jingushi K, Hirono T, Ueda Y, Kitae K, Nakata W, et al. The miR-130 family promotes cell migration and invasion in bladder cancer through FAK and Akt phosphorylation by regulating PTEN. Sci Rep. 2016;6:20574 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 6
Benedykcinska A, Ferreira A, Lau J, Broni J, Richard Loendt A, Henriquez N, et al. Generation of brain tumours in mice by Cre-mediated recombination of neural progenitors in situ with the tamoxifen metabolite endoxifen. Dis Model Mech. 2016;9:211-20 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
  • 免疫印迹; 人类; 图 5
Vural A, Al Khodor S, Cheung G, Shi C, Srinivasan L, McQuiston T, et al. Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection. J Immunol. 2016;196:846-56 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3h
Li Y, Shen C, Zhu B, Shi F, Eisen H, Chen J. Persistent Antigen and Prolonged AKT-mTORC1 Activation Underlie Memory CD8 T Cell Impairment in the Absence of CD4 T Cells. J Immunol. 2015;195:1591-8 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1d
  • 免疫组化; 人类; 图 2c
Zidek L, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, et al. Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice. EMBO Rep. 2015;16:1022-36 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Momeny M, Saunus J, Marturana F, McCart Reed A, Black D, Sala G, et al. Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines. Oncotarget. 2015;6:3932-46 pubmed
  • 免疫印迹; 小鼠; 图 7
Shrestha S, Yang K, Guy C, Vogel P, Neale G, Chi H. Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. Nat Immunol. 2015;16:178-87 pubmed 出版商
Shelby S, Veatch S, Holowka D, Baird B. Functional nanoscale coupling of Lyn kinase with IgE-Fc?RI is restricted by the actin cytoskeleton in early antigen-stimulated signaling. Mol Biol Cell. 2016;27:3645-3658 pubmed
Kalland M, Oberprieler N, Vang T, Tasken K, Torgersen K. T cell-signaling network analysis reveals distinct differences between CD28 and CD2 costimulation responses in various subsets and in the MAPK pathway between resting and activated regulatory T cells. J Immunol. 2011;187:5233-45 pubmed 出版商
Soond D, Bjørgo E, Moltu K, Dale V, Patton D, Torgersen K, et al. PI3K p110delta regulates T-cell cytokine production during primary and secondary immune responses in mice and humans. Blood. 2010;115:2203-13 pubmed 出版商
Francisco L, Salinas V, Brown K, Vanguri V, Freeman G, Kuchroo V, et al. PD-L1 regulates the development, maintenance, and function of induced regulatory T cells. J Exp Med. 2009;206:3015-29 pubmed 出版商
产品信息
SKU号 :
4075S
产品名称 :
Phospho-Akt (Ser473) (D9E) XP® Rabbit mAb (Alexa Fluor® 647 Conjugate)
规格 :
100微升
Price-(USD) :
321美元
物种x :
H, M, R, Hm, Mk, Dm, Z, B, (C, X, Dg, Pg)
应用 :
流式细胞仪
产品种类 :
PI3K / Akt Signaling
运输温度 :
储存温度 :
4°C
产品类型 :
单克隆抗体
分子量 :
60
宿主 :
靶标 :
Akt1(Ser473)磷酸盐/Akt2(Ser474)磷酸盐/Akt3(Ser472)磷酸盐
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。