产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
LC3A/B抗体
目录 :
4108
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, , 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-冰冻切片, 其他
文章摘录数: 48
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 5b, 5c
Han H, Kim S, Kim Y, Jang S, Kwon Y, Choi D, et al. A novel role of CRTC2 in promoting nonalcoholic fatty liver disease. Mol Metab. 2022;55:101402 pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Lü Z, Liu H, Song N, Liang Y, Zhu J, Chen J, et al. METTL14 aggravates podocyte injury and glomerulopathy progression through N6-methyladenosine-dependent downregulating of Sirt1. Cell Death Dis. 2021;12:881 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6a
Liu M, Shan M, Zhang Y, Guo Z. Progranulin Protects Against Airway Remodeling Through the Modulation of Autophagy via HMGB1 Suppression in House Dust Mite-Induced Chronic Asthma. J Inflamm Res. 2021;14:3891-3904 pubmed 出版商
  • 免疫细胞化学; 人类; 图 a12s8a, a8s4b
  • 免疫印迹; 人类; 图 3c
Wang X, Li X, Lin F, Sun H, Lin Y, Wang Z, et al. The lnc-CTSLP8 upregulates CTSL1 as a competitive endogenous RNA and promotes ovarian cancer metastasis. J Exp Clin Cancer Res. 2021;40:151 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 4
Higgins N, Greenslade J, Wu J, Miranda E, Galliciotti G, Monteiro M. Serpin neuropathology in the P497S UBQLN2 mouse model of ALS/FTD. Brain Pathol. 2021;:e12948 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
  • 免疫印迹; 小鼠; 图 1a
Kim D, Park J, Choi H, Kim C, Bae E, Ma S, et al. The critical role of FXR is associated with the regulation of autophagy and apoptosis in the progression of AKI to CKD. Cell Death Dis. 2021;12:320 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
Choi S, Agatisa Boyle C, Gonen A, Kim A, Kim J, Alekseeva E, et al. Intracellular AIBP (Apolipoprotein A-I Binding Protein) Regulates Oxidized LDL (Low-Density Lipoprotein)-Induced Mitophagy in Macrophages. Arterioscler Thromb Vasc Biol. 2020;:ATVBAHA120315485 pubmed 出版商
  • 免疫印迹; 人类; 图 3c
Huang Z, Zhao J, Wang W, Zhou J, Zhang J. Depletion of LncRNA NEAT1 Rescues Mitochondrial Dysfunction Through NEDD4L-Dependent PINK1 Degradation in Animal Models of Alzheimer's Disease. Front Cell Neurosci. 2020;14:28 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Ormeño F, Hormazabal J, Moreno J, Riquelme F, Rios J, Criollo A, et al. Chaperone Mediated Autophagy Degrades TDP-43 Protein and Is Affected by TDP-43 Aggregation. Front Mol Neurosci. 2020;13:19 pubmed 出版商
  • 免疫印迹; 人类; 图 3a, 1d
Liu K, Yu Q, Li H, Xie C, Wu Y, Ma D, et al. BIRC7 promotes epithelial-mesenchymal transition and metastasis in papillary thyroid carcinoma through restraining autophagy. Am J Cancer Res. 2020;10:78-94 pubmed
  • 免疫印迹; 大鼠; 1:1000; 图 5a
Jiang G, Xin R, Yuan W, Zhang L, Meng X, Sun W, et al. Ligustrazine ameliorates acute kidney injury through downregulation of NOD2‑mediated inflammation. Int J Mol Med. 2020;45:731-742 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6a
Zuo Z, Ji M, Zhao K, Su Z, Li P, Hou D, et al. CD47 Deficiency Attenuates Isoproterenol-Induced Cardiac Remodeling in Mice. Oxid Med Cell Longev. 2019;2019:7121763 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4c
Wang X, Zhao L, Ajay A, Jiao B, Zhang X, Wang C, et al. QiDiTangShen Granules Activate Renal Nutrient-Sensing Associated Autophagy in db/db Mice. Front Physiol. 2019;10:1224 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1500; 图 1c
Wu Y, Xu H, Li Y, Huang D, Chen L, Hu Y, et al. miRNA-344b-1-3p modulates the autophagy of NR8383 cells during Aspergillus fumigatus infection via TLR2. Exp Ther Med. 2019;18:139-146 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5c
Chang H, Di T, Wang Y, Zeng X, Li G, Wan Q, et al. Seipin deletion in mice enhances phosphorylation and aggregation of tau protein through reduced neuronal PPARγ and insulin resistance. Neurobiol Dis. 2019;127:350-361 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3a
Shao J, Miao C, Geng Z, Gu M, Wu Y, Li Q. Effect of eNOS on Ischemic Postconditioning-Induced Autophagy against Ischemia/Reperfusion Injury in Mice. Biomed Res Int. 2019;2019:5201014 pubmed 出版商
  • 免疫组化; 小鼠; 图 3d
  • 免疫印迹; 小鼠; 图 2b
Yang Z, Huang C, Wu Y, Chen B, Zhang W, Zhang J. Autophagy Protects the Blood-Brain Barrier Through Regulating the Dynamic of Claudin-5 in Short-Term Starvation. Front Physiol. 2019;10:2 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 9e
Jassim A, Inman D. Evidence of Hypoxic Glial Cells in a Model of Ocular Hypertension. Invest Ophthalmol Vis Sci. 2019;60:1-15 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 3b
  • 免疫印迹; 小鼠; 图 3a
Rai S, Arasteh M, Jefferson M, Pearson T, Wang Y, Zhang W, et al. The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis. Autophagy. 2019;15:599-612 pubmed 出版商
  • 免疫印迹; 人类; 图 4e
Wang H, Bu L, Wang C, Zhang Y, Zhou H, Zhang X, et al. The Hsp70 inhibitor 2-phenylethynesulfonamide inhibits replication and carcinogenicity of Epstein-Barr virus by inhibiting the molecular chaperone function of Hsp70. Cell Death Dis. 2018;9:734 pubmed 出版商
  • 其他; 人类; 图 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1g, 2e
Fletcher K, Ulferts R, Jacquin E, Veith T, Gammoh N, Arasteh J, et al. The WD40 domain of ATG16L1 is required for its non-canonical role in lipidation of LC3 at single membranes. EMBO J. 2018;37: pubmed 出版商
  • 免疫印迹; 小鼠; 图 1d
Guo H, Chitiprolu M, Roncevic L, Javalet C, Hemming F, Trung M, et al. Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy. Dev Cell. 2017;43:716-730.e7 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2a
Viana Huete V, Guillen C, García G, Fernandez S, García Aguilar A, Kahn C, et al. Male Brown Fat-Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity. Endocrinology. 2018;159:323-340 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Zhou Y, Huang N, Wu J, Zhen N, Li N, Li Y, et al. Silencing of NRAGE induces autophagy via AMPK/Ulk1/Atg13 signaling pathway in NSCLC cells. Tumour Biol. 2017;39:1010428317709676 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5c
Qian Q, Liu Q, Zhou D, Pan H, Liu Z, He F, et al. Brain-specific ablation of Efr3a promotes adult hippocampal neurogenesis via the brain-derived neurotrophic factor pathway. FASEB J. 2017;31:2104-2113 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7g
Hammerling B, Najor R, Cortez M, Shires S, Leon L, Gonzalez E, et al. A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Nat Commun. 2017;8:14050 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3e
Liu J, Wang H, Gu J, Deng T, Yuan Z, Hu B, et al. BECN1-dependent CASP2 incomplete autophagy induction by binding to rabies virus phosphoprotein. Autophagy. 2017;13:739-753 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Wang Q, Wu S, Zhu H, Ding Y, Dai X, Ouyang C, et al. Deletion of PRKAA triggers mitochondrial fission by inhibiting the autophagy-dependent degradation of DNM1L. Autophagy. 2017;13:404-422 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 2b
Yan H, Gao Y, Zhang Y. Inhibition of JNK suppresses autophagy and attenuates insulin resistance in a rat model of nonalcoholic fatty liver disease. Mol Med Rep. 2017;15:180-186 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1c
Yao J, Jia L, Feathers K, Lin C, Khan N, Klionsky D, et al. Autophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration. Autophagy. 2016;12:2439-2450 pubmed
  • 免疫印迹; 人类; 图 3d
Zhao Y, Fan D, Ru B, Cheng K, Hu S, Zhang J, et al. 6-C-(E-phenylethenyl)naringenin induces cell growth inhibition and cytoprotective autophagy in colon cancer cells. Eur J Cancer. 2016;68:38-50 pubmed 出版商
  • 免疫细胞化学; 人类; 图 6a
Kim S, Roy S, Chen B, Nguyen T, McMonigle R, McCracken A, et al. Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways. J Clin Invest. 2016;126:4088-4102 pubmed 出版商
  • 免疫印迹; 人类
Wang Y, Sun H, Wang J, Wang H, Meng L, Xu C, et al. DNA-PK-mediated phosphorylation of EZH2 regulates the DNA damage-induced apoptosis to maintain T-cell genomic integrity. Cell Death Dis. 2016;7:e2316 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 1d
Zeng J, Jing Y, Shi R, Pan X, Lai F, Liu W, et al. Autophagy regulates biliary differentiation of hepatic progenitor cells through Notch1 signaling pathway. Cell Cycle. 2016;15:1602-10 pubmed 出版商
  • 免疫印迹; 斑马鱼; 1:1000; 图 s1c
Huang G, Zhang F, Ye Q, Wang H. The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erb? and indirectly via Cebpb/(C/ebp?) in zebrafish. Autophagy. 2016;12:1292-309 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5
Krall A, Xu S, Graeber T, Braas D, Christofk H. Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. Nat Commun. 2016;7:11457 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 S8
Basisty N, Dai D, Gagnidze A, Gitari L, Fredrickson J, Maina Y, et al. Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: 'reverse' antagonistic pleiotropy?. Aging Cell. 2016;15:634-45 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Stojcheva N, Schechtmann G, Sass S, Roth P, Florea A, Stefanski A, et al. MicroRNA-138 promotes acquired alkylator resistance in glioblastoma by targeting the Bcl-2-interacting mediator BIM. Oncotarget. 2016;7:12937-50 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Yang X, Liang L, Zong C, Lai F, Zhu P, Liu Y, et al. Kupffer cells-dependent inflammation in the injured liver increases recruitment of mesenchymal stem cells in aging mice. Oncotarget. 2016;7:1084-95 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 S1
  • 免疫印迹; 小鼠; 1:1000; 图 1B
Sin J, Andres A, Taylor D, Weston T, Hiraumi Y, Stotland A, et al. Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts. Autophagy. 2016;12:369-80 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Levin A, Koelink P, Bloemendaal F, Vos A, D Haens G, van den Brink G, et al. Autophagy Contributes to the Induction of Anti-TNF Induced Macrophages. J Crohns Colitis. 2016;10:323-9 pubmed 出版商
Bartolomé A, García Aguilar A, Asahara S, Kido Y, Guillen C, Pajvani U, et al. MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling. Mol Cell Biol. 2017;37: pubmed 出版商
Chen X, Clark J, Wunderlich M, Fan C, Davis A, Chen S, et al. Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine. Autophagy. 2017;13:955-966 pubmed 出版商
Moon J, Lee J, Lee Y, Park S. Autophagy flux induced by ginsenoside-Rg3 attenuates human prion protein-mediated neurotoxicity and mitochondrial dysfunction. Oncotarget. 2016;7:85697-85708 pubmed 出版商
Sasaki T, Lian S, Khan A, Llop J, Samuelson A, Chen W, et al. Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase. Autophagy. 2017;13:386-403 pubmed 出版商
Moon J, Lee J, Nazim U, Lee Y, Seol J, Eo S, et al. Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells. Oncotarget. 2016;7:29989-30002 pubmed 出版商
Moon J, Lee J, Lee Y, Park S. Hinokitiol protects primary neuron cells against prion peptide-induced toxicity via autophagy flux regulated by hypoxia inducing factor-1. Oncotarget. 2016;7:29944-57 pubmed 出版商
产品信息
SKU号 :
4108S
产品名称 :
LC3A/B抗体
规格 :
100微升
Price-(USD) :
235美元
物种x :
H, M, R, (Mk, C, X, Z, Dg)
应用 :
流式细胞仪
产品种类 :
自噬
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
多克隆抗体
分子量 :
14, 16
宿主 :
靶标 :
LC3A/LC3B
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。