产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
切断的Notch1(Val1744)(D3B8)兔单克隆抗体
目录 :
4147
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
D3B8
反应物种 :
仓鼠, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
文章摘录数: 89
出版应用/物种/样本/稀释参考文献
  • 免疫印迹基因敲除验证; 人类; 1:1000; 图 2e
Wang Y, Liu I, Chen K, Wu H. NOTCH1 signaling promotes protein stability of HER3 through the AKT pathway in squamous cell carcinoma of head and neck. Oncogenesis. 2021;10:59 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s9b
Yamagishi M, Kubokawa M, Kuze Y, Suzuki A, Yokomizo A, Kobayashi S, et al. Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma. Nat Commun. 2021;12:4821 pubmed 出版商
  • 免疫印迹; 人类; 图 5c
Roper N, Velez M, Chiappori A, Kim Y, Wei J, Sindiri S, et al. Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer. Nat Commun. 2021;12:3880 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 3a
Ofek S, Wiszniak S, Kagan S, Tondl M, Schwarz Q, Kalcheim C. Notch signaling is a critical initiator of roof plate formation as revealed by the use of RNA profiling of the dorsal neural tube. BMC Biol. 2021;19:84 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Ni W, Chen Z, Zhou X, Yang R, Yu M, Lu J, et al. Targeting Notch and EGFR signaling in human mucoepidermoid carcinoma. Signal Transduct Target Ther. 2021;6:27 pubmed 出版商
  • 免疫组化; 人类; 1:50; 图 1f
  • 免疫印迹; 人类; 1:1000; 图 1c
Pan L, Lemieux M, Thomas T, Rogers J, Lipper C, Lee W, et al. IER5, a DNA damage response gene, is required for Notch-mediated induction of squamous cell differentiation. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5c
Eyler C, Matsunaga H, Hovestadt V, Vantine S, van Galen P, Bernstein B. Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance. Genome Biol. 2020;21:174 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1a
Caolo V, Debant M, Endesh N, Futers T, Lichtenstein L, Bartoli F, et al. Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 图 s4c
Liao T, Lin C, Jiang J, Yang S, Teng H, Yang M. Harnessing stemness and PD-L1 expression by AT-rich interaction domain-containing protein 3B in colorectal cancer. Theranostics. 2020;10:6095-6112 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3f, 3h
Kuang Y, Golan O, Preusse K, Cain B, Christensen C, Salomone J, et al. Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 1:3000
Park D, Cheng J, McGrath J, Lim M, Cushman C, Swanson S, et al. Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis. Nat Cell Biol. 2020;22:603-615 pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Liu H, Mei F, Yang W, Wang H, Wong E, Cai J, et al. Epac1 inhibition ameliorates pathological angiogenesis through coordinated activation of Notch and suppression of VEGF signaling. Sci Adv. 2020;6:eaay3566 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 1a
Travisano S, Oliveira V, Prados B, Grego Bessa J, Piñeiro Sabarís R, Bou V, et al. Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. elife. 2019;8: pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 3d
Stupnikov M, Yang Y, Mori M, LU J, Cardoso W. Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 图 1e
Chen H, Poran A, Unni A, Huang S, Elemento O, Snoeck H, et al. Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells. J Exp Med. 2019;216:674-687 pubmed 出版商
  • 免疫印迹; 人类; 图 6c
  • 免疫组化-石蜡切片; 小鼠; 图 5c
  • 免疫印迹; 小鼠; 图 5d
Li L, Guturi K, Gautreau B, Patel P, Saad A, Morii M, et al. Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis. J Clin Invest. 2018;128:4525-4542 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:150; 图 5a
Eley L, Alqahtani A, MacGrogan D, Richardson R, Murphy L, Salguero Jimenez A, et al. A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice. elife. 2018;7: pubmed 出版商
  • 免疫印迹; 人类; 图 s5j
Das A, Huang G, Bonkowski M, Longchamp A, Li C, Schultz M, et al. Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging. Cell. 2018;173:74-89.e20 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2a
Hu X, Das B, Hou H, He W, Yan R. BACE1 deletion in the adult mouse reverses preformed amyloid deposition and improves cognitive functions. J Exp Med. 2018;215:927-940 pubmed 出版商
  • 免疫印迹; 人类; 图 s3i
Nandagopal N, Santat L, Lebon L, Sprinzak D, Bronner M, Elowitz M. Dynamic Ligand Discrimination in the Notch Signaling Pathway. Cell. 2018;172:869-880.e19 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 1a
Steinbuck M, Arakcheeva K, Winandy S. Novel TCR-Mediated Mechanisms of Notch Activation and Signaling. J Immunol. 2018;200:997-1007 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 1b
Fang J, Coon B, Gillis N, Chen Z, Qiu J, Chittenden T, et al. Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. Nat Commun. 2017;8:2149 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1e
Polacheck W, Kutys M, Yang J, Eyckmans J, Wu Y, Vasavada H, et al. A non-canonical Notch complex regulates adherens junctions and vascular barrier function. Nature. 2017;552:258-262 pubmed 出版商
  • 免疫印迹; 人类; 图 3e
Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Sawaguchi S, Varshney S, Ogawa M, Sakaidani Y, Yagi H, Takeshita K, et al. O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals. elife. 2017;6: pubmed 出版商
  • 免疫组化; 大鼠; 1:100; 图 1e
  • 免疫印迹; 大鼠; 1:300; 图 1a
Zeng W, Han Y, Zhu G, Huang L, Deng Y, Wang Q, et al. Hypertonic saline attenuates expression of Notch signaling and proinflammatory mediators in activated microglia in experimentally induced cerebral ischemia and hypoxic BV-2 microglia. BMC Neurosci. 2017;18:32 pubmed 出版商
  • 免疫印迹; 人类; 图 5c
Mandl M, Zhang S, Ulrich M, Schmoeckel E, Mayr D, Vollmar A, et al. Inhibition of Cdk5 induces cell death of tumor-initiating cells. Br J Cancer. 2017;116:912-922 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3g
Xu J, Zhou W, Yang F, Chen G, Li H, Zhao Y, et al. The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor. Nat Commun. 2017;8:14002 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 3c
Hirai M, Arita Y, McGlade C, Lee K, Chen J, Evans S. Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. J Clin Invest. 2017;127:569-582 pubmed 出版商
  • 免疫印迹; 人类; 图 4f
Li S, Hu H, He Z, Liang D, Sun R, Lan K. Fine-Tuning of the Kaposi's Sarcoma-Associated Herpesvirus Life Cycle in Neighboring Cells through the RTA-JAG1-Notch Pathway. PLoS Pathog. 2016;12:e1005900 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 3c
Kuzmanov U, Guo H, Buchsbaum D, Cosme J, Abbasi C, Isserlin R, et al. Global phosphoproteomic profiling reveals perturbed signaling in a mouse model of dilated cardiomyopathy. Proc Natl Acad Sci U S A. 2016;113:12592-12597 pubmed
  • 免疫印迹; 人类; 1:500; 图 3
Greene L, Nathwani S, Zisterer D. Inhibition of ?-secretase activity synergistically enhances tumour necrosis factor-related apoptosis-inducing ligand induced apoptosis in T-cell acute lymphoblastic leukemia cells via upregulation of death receptor 5. Oncol Lett. 2016;12:2900-2905 pubmed
  • 免疫印迹; 人类; 图 s3
Stoyanova T, Riedinger M, Lin S, Faltermeier C, Smith B, Zhang K, et al. Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016;113:E6457-E6466 pubmed
  • 免疫印迹; 人类; 1:800; 图 1b
Asnaghi L, Tripathy A, Yang Q, Kaur H, Hanaford A, Yu W, et al. Targeting Notch signaling as a novel therapy for retinoblastoma. Oncotarget. 2016;7:70028-70044 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed
  • 免疫印迹; 人类; 1:500; 图 2b
Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7d
Ramo K, Sugamura K, Craige S, Keaney J, Davis R. Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Deskin B, Lasky J, Zhuang Y, Shan B. Requirement of HDAC6 for activation of Notch1 by TGF-?1. Sci Rep. 2016;6:31086 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4d
Phillips E, Lang V, Bohlen J, Bethke F, Puccio L, Tichy D, et al. Targeting atypical protein kinase C iota reduces viability in glioblastoma stem-like cells via a notch signaling mechanism. Int J Cancer. 2016;139:1776-87 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2
Carofino B, Ayanga B, Tracey L, Brooke Bisschop T, Justice M. PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL. Biol Open. 2016;5:645-53 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Huang G, Yang X, Chen K, Xing J, Guo L, Zhu L, et al. Porf-2 Inhibits Neural Stem Cell Proliferation Through Wnt/?-Catenin Pathway by Its GAP Domain. Front Cell Neurosci. 2016;10:85 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Lynch J, McEwen R, Crafter C, McDermott U, Garnett M, Barry S, et al. Identification of differential PI3K pathway target dependencies in T-cell acute lymphoblastic leukemia through a large cancer cell panel screen. Oncotarget. 2016;7:22128-39 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 6
  • 免疫印迹; 小鼠; 1:1000; 图 6
Wang W, Jossin Y, Chai G, Lien W, Tissir F, Goffinet A. Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016;7:10936 pubmed 出版商
  • 免疫组化; 人类; 1:100; 图 4
Drier Y, Cotton M, Williamson K, Gillespie S, Ryan R, Kluk M, et al. An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma. Nat Genet. 2016;48:265-72 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 2, 3
Tominaga A, Cai T, Takagi Niidome S, Iwatsubo T, Tomita T. Conformational Changes in Transmembrane Domain 4 of Presenilin 1 Are Associated with Altered Amyloid-β 42 Production. J Neurosci. 2016;36:1362-72 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Merk H, Zhang S, Lehr T, Müller C, Ulrich M, Bibb J, et al. Inhibition of endothelial Cdk5 reduces tumor growth by promoting non-productive angiogenesis. Oncotarget. 2016;7:6088-104 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Noh H, Hah Y, Ha J, Kang M, Zada S, Rha S, et al. Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. Oncotarget. 2016;7:4632-46 pubmed 出版商
  • 免疫印迹; 仓鼠
Bolduc D, Montagna D, Gu Y, Selkoe D, Wolfe M. Nicastrin functions to sterically hinder γ-secretase-substrate interactions driven by substrate transmembrane domain. Proc Natl Acad Sci U S A. 2016;113:E509-18 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5d
  • 免疫印迹; 人类; 图 5b
Zhang S, Schneider L, Vick B, Grunert M, Jeremias I, Menche D, et al. Anti-leukemic effects of the V-ATPase inhibitor Archazolid A. Oncotarget. 2015;6:43508-28 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s7d
Herranz D, Ambesi Impiombato A, Sudderth J, Sánchez Martín M, Belver L, Tosello V, et al. Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia. Nat Med. 2015;21:1182-9 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5a
Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, et al. The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS Genet. 2015;11:e1005503 pubmed 出版商
  • 免疫印迹; 人类; 图 8
Ray A, Vasudevan S, Sengupta S. 6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death. PLoS ONE. 2015;10:e0137614 pubmed 出版商
  • 免疫印迹; 小鼠; 图 9a
Xie C, Wei D, Zhao L, Marchetto S, Mei L, Borg J, et al. Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis. J Cell Biol. 2015;209:721-37 pubmed 出版商
  • 免疫印迹; 人类; 图 s4
Sato M, Rodríguez Barrueco R, Yu J, Do C, Silva J, Gautier J. MYC is a critical target of FBXW7. Oncotarget. 2015;6:3292-305 pubmed
  • 免疫印迹; 人类; 1:500
Nguyen D, Rubinstein L, Takebe N, Miele L, Tomaszewski J, Ivy P, et al. Notch1 phenotype and clinical stage progression in non-small cell lung cancer. J Hematol Oncol. 2015;8:9 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:100
  • 免疫印迹; 人类; 1:800
Lim K, Brandt W, Heth J, Muraszko K, Fan X, Bar E, et al. Lateral inhibition of Notch signaling in neoplastic cells. Oncotarget. 2015;6:1666-77 pubmed
  • 免疫印迹; 人类
So J, Lin J, Wahler J, Liby K, Sporn M, Suh N. A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer. PLoS ONE. 2014;9:e107616 pubmed 出版商
  • 免疫印迹; 人类
Aydin I, Melamed R, Adams S, Castillo Martin M, Demir A, Bryk D, et al. FBXW7 mutations in melanoma and a new therapeutic paradigm. J Natl Cancer Inst. 2014;106:dju107 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
Kumar V, Palermo R, Talora C, Campese A, Checquolo S, Bellavia D, et al. Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia. Leukemia. 2014;28:2324-35 pubmed 出版商
  • 免疫印迹; 人类
Yoshida R, Nagata M, Nakayama H, Niimori Kita K, Hassan W, Tanaka T, et al. The pathological significance of Notch1 in oral squamous cell carcinoma. Lab Invest. 2013;93:1068-81 pubmed 出版商
Dabelsteen S, Pallesen E, Marinova I, Nielsen M, Adamopoulou M, Rømer T, et al. Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model. Dev Cell. 2020;54:669-684.e7 pubmed 出版商
Dai K, Huang L, Huang Y, Chen Z, Yang L, Jiang Y. 1810011o10 Rik Inhibits the Antitumor Effect of Intratumoral CD8+ T Cells through Suppression of Notch2 Pathway in a Murine Hepatocellular Carcinoma Model. Front Immunol. 2017;8:320 pubmed 出版商
Machado A, Rodríguez Expósito E, Lopez M, Hernandez M. Phylogenetic analysis of the genus Laparocerus, with comments on colonisation and diversification in Macaronesia (Coleoptera, Curculionidae, Entiminae). Zookeys. 2017;:1-77 pubmed 出版商
Liao X, Zhang A, Zheng M, Li M, Chen C, Xu H, et al. Chemical or genetic Pin1 inhibition exerts potent anticancer activity against hepatocellular carcinoma by blocking multiple cancer-driving pathways. Sci Rep. 2017;7:43639 pubmed 出版商
Kim W, Khan S, Gvozdenovic Jeremic J, Kim Y, Dahlman J, Kim H, et al. Hippo signaling interactions with Wnt/?-catenin and Notch signaling repress liver tumorigenesis. J Clin Invest. 2017;127:137-152 pubmed 出版商
Ezratty E, Pasolli H, Fuchs E. A Presenilin-2-ARF4 trafficking axis modulates Notch signaling during epidermal differentiation. J Cell Biol. 2016;214:89-101 pubmed 出版商
Gama Norton L, Ferrando E, Ruiz Herguido C, Liu Z, Liu Z, Guiu J, et al. Notch signal strength controls cell fate in the haemogenic endothelium. Nat Commun. 2015;6:8510 pubmed 出版商
Stasiulewicz M, Gray S, Mastromina I, Silva J, Björklund M, Seymour P, et al. A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo. Development. 2015;142:2291-303 pubmed 出版商
Lin M, Price E, Boatman S, Hagedorn E, Trompouki E, Satishchandran S, et al. Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling. elife. 2015;4: pubmed 出版商
Rettig E, Chung C, Bishop J, Howard J, Sharma R, Li R, et al. Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features. Cancer Prev Res (Phila). 2015;8:287-95 pubmed 出版商
Jegalian A, Bodo J, Hsi E. NOTCH1 intracellular domain immunohistochemistry as a diagnostic tool to distinguish T-lymphoblastic lymphoma from thymoma. Am J Surg Pathol. 2015;39:565-72 pubmed 出版商
Rowe M, Raithatha S, Shannon Lowe C. Counteracting effects of cellular Notch and Epstein-Barr virus EBNA2: implications for stromal effects on virus-host interactions. J Virol. 2014;88:12065-76 pubmed 出版商
Zhang X, Yang B, Wang J, Mo X, Zhang J, Hua Z. FADD is essential for glucose uptake and survival of thymocytes. Biochem Biophys Res Commun. 2014;451:202-7 pubmed 出版商
Capaccione K, Hong X, Morgan K, Liu W, Bishop J, Liu L, et al. Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma. Oncotarget. 2014;5:3636-50 pubmed
Nickel N, Godau J, Willie B, Duda G, Schwarzer R, Cirovic B, et al. Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model. Blood Cancer J. 2014;4:e217 pubmed 出版商
South A, Purdie K, Watt S, Haldenby S, den Breems N, Dimon M, et al. NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis. J Invest Dermatol. 2014;134:2630-2638 pubmed 出版商
Hagenbeek T, Wu X, Choy L, Sanchez Irizarry C, Seshagiri S, Stinson J, et al. Murine Pten(-/-) T-ALL requires non-redundant PI3K/mTOR and DLL4/Notch1 signals for maintenance and ?c/TCR signals for thymic exit. Cancer Lett. 2014;346:237-48 pubmed 出版商
Simonetti G, Carette A, Silva K, Wang H, De Silva N, Heise N, et al. IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity. J Exp Med. 2013;210:2887-902 pubmed 出版商
Arruga F, Gizdić B, Serra S, Vaisitti T, Ciardullo C, Coscia M, et al. Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia. Leukemia. 2014;28:1060-70 pubmed 出版商
Carofino B, Ayanga B, Justice M. A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL). Dis Model Mech. 2013;6:1494-506 pubmed 出版商
Caliceti C, Aquila G, Pannella M, Morelli M, Fortini C, Pinton P, et al. 17β-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells. PLoS ONE. 2013;8:e71440 pubmed 出版商
Mezquita B, Mezquita J, Barrot C, Carvajal S, Pau M, Mezquita P, et al. A truncated-Flt1 isoform of breast cancer cells is upregulated by Notch and downregulated by retinoic acid. J Cell Biochem. 2014;115:52-61 pubmed 出版商
Kluk M, Ashworth T, Wang H, Knoechel B, Mason E, Morgan E, et al. Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry. PLoS ONE. 2013;8:e67306 pubmed 出版商
Wang X, Yu H, Linnoila R, Li L, Li D, Mo B, et al. Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer. Oncotarget. 2013;4:739-50 pubmed
Zhao J, Ma M, Ren H, Liu Z, Edelman M, Pan H, et al. Anti-HDGF targets cancer and cancer stromal stem cells resistant to chemotherapy. Clin Cancer Res. 2013;19:3567-76 pubmed 出版商
Tezgel A, González Pérez G, Telfer J, Osborne B, Minter L, Tew G. Novel protein transduction domain mimics as nonviral delivery vectors for siRNA targeting NOTCH1 in primary human T cells. Mol Ther. 2013;21:201-9 pubmed 出版商
Sakamoto K, Fujii T, Kawachi H, Miki Y, Omura K, Morita K, et al. Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms. Lab Invest. 2012;92:688-702 pubmed 出版商
Zheng W, Tammela T, Yamamoto M, Anisimov A, Holopainen T, Kaijalainen S, et al. Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor. Blood. 2011;118:1154-62 pubmed 出版商
Treanor L, Volanakis E, Zhou S, Lu T, Sherr C, Sorrentino B. Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies. Blood. 2011;117:5453-62 pubmed 出版商
产品信息
SKU号 :
4147P
产品名称 :
切断的Notch1(Val1744)(D3B8)兔单克隆抗体
规格 :
40微升
Price-(USD) :
123美元
物种x :
H, M, R
应用 :
染色质免疫沉淀
产品种类 :
发育生物学
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
110
宿主 :
靶标 :
Notch1 (Val1744, small subunit) cleaved
最初蛋白 :
Notch 1
别名 :
NOTC1,NOTCH1,Neurogenic locus notch homolog protein 1,Notch 1,Notch 1 extracellular truncation,Notch 1 intracellular domain,Notch homolog 1, translocation-associated (Drosophila),TAN1,Translocation-associated notch protein TAN-1,hN1
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。