产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
磷脂酰肌醇(-3)激酶p110α(C73F8)兔单克隆抗体
目录 :
4249
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
C73F8
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫印迹基因敲除验证
文章摘录数: 82
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 4a
Li R, Hao Y, Wang Q, Meng Y, Wu K, Liu C, et al. ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation. Cell Death Dis. 2021;12:911 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6d
Xu X, Lei Y, Chen L, Zhou H, Liu H, Jiang J, et al. Phosphorylation of NF-κBp65 drives inflammation-mediated hepatocellular carcinogenesis and is a novel therapeutic target. J Exp Clin Cancer Res. 2021;40:253 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2a
  • 免疫印迹; 人类; 1:1000; 图 2b
Guo J, Cheng J, Zheng N, Zhang X, Dai X, Zhang L, et al. Copper Promotes Tumorigenesis by Activating the PDK1-AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner. Adv Sci (Weinh). 2021;8:e2004303 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4f
Kearney A, Norris D, Ghomlaghi M, Kin Lok Wong M, Humphrey S, Carroll L, et al. Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis. elife. 2021;10: pubmed 出版商
  • 免疫印迹; 大鼠; 图 6a
Chen Y, Chen Y, Jiang X, Shi M, Yang Z, Chen Z, et al. Vascular Adventitial Fibroblasts-Derived FGF10 Promotes Vascular Smooth Muscle Cells Proliferation and Migration in vitro and the Neointima Formation in vivo. J Inflamm Res. 2021;14:2207-2223 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 4c
  • 免疫印迹; 人类; 1:1000; 图 4b
Wang P, Zhao L, Gong S, Xiong S, Wang J, Zou D, et al. HIF1α/HIF2α-Sox2/Klf4 promotes the malignant progression of glioblastoma via the EGFR-PI3K/AKT signalling pathway with positive feedback under hypoxia. Cell Death Dis. 2021;12:312 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Zhang Y, Du P, Li Y, Zhu Q, Song X, Liu S, et al. TASP1 Promotes Gallbladder Cancer Cell Proliferation and Metastasis by Up-regulating FAM49B via PI3K/AKT Pathway. Int J Biol Sci. 2020;16:739-751 pubmed 出版商
  • 免疫印迹; 大鼠; 图 7a
  • 免疫印迹; 人类; 图 10a
Zhang Y, Mao X, Chen W, Guo X, Yu L, Jiang F, et al. A Discovery of Clinically Approved Formula FBRP for Repositioning to Treat HCC by Inhibiting PI3K/AKT/NF-κB Activation. Mol Ther Nucleic Acids. 2020;19:890-904 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Veschi V, Mangiapane L, Nicotra A, Di Franco S, Scavo E, Apuzzo T, et al. Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant. Oncogene. 2020;39:987-1003 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6a
Ghezzi C, Wong A, Chen B, Ribalet B, Damoiseaux R, Clark P. A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. Nat Commun. 2019;10:5444 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2b
  • 免疫印迹; 人类; 1:1000; 图 2a
VASAN N, Razavi P, Johnson J, Shao H, Shah H, Antoine A, et al. Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors. Science. 2019;366:714-723 pubmed 出版商
  • 免疫印迹; 人类; 图 3d
Lundby A, Franciosa G, Emdal K, Refsgaard J, Gnosa S, Bekker Jensen D, et al. Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites. Cell. 2019;179:543-560.e26 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 6a
Luo X, Jiang X, Li J, Bai Y, Li Z, Wei P, et al. Insulin-like growth factor-1 attenuates oxidative stress-induced hepatocyte premature senescence in liver fibrogenesis via regulating nuclear p53-progerin interaction. Cell Death Dis. 2019;10:451 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 s1a
Sivaram N, McLaughlin P, Han H, Petrenko O, Jiang Y, Ballou L, et al. Tumor-intrinsic PIK3CA represses tumor immunogenecity in a model of pancreatic cancer. J Clin Invest. 2019;130: pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Nan H, Han L, Ma J, Yang C, Su R, He J. STX3 represses the stability of the tumor suppressor PTEN to activate the PI3K-Akt-mTOR signaling and promotes the growth of breast cancer cells. Biochim Biophys Acta Mol Basis Dis. 2018;1864:1684-1692 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3c
Simond A, Rao T, Zuo D, Zhao J, Muller W. ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor. Oncogene. 2017;36:6059-6066 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 4a
  • 免疫沉淀; 人类; 图 1d
Carpenter V, Chen Y, Dolat L, Valdivia R. The Effector TepP Mediates Recruitment and Activation of Phosphoinositide 3-Kinase on Early Chlamydia trachomatis Vacuoles. mSphere. 2017;2: pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Hu L, Liang S, Chen H, Lv T, Wu J, Chen D, et al. ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis. Proc Natl Acad Sci U S A. 2017;114:E3964-E3973 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4a
Zhang X, Spiegelman N, Nelson O, Jing H, Lin H. SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation. elife. 2017;6: pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Liu S, Gao G, Yan D, Chen X, Yao X, Guo S, et al. Effects of miR-145-5p through NRAS on the cell proliferation, apoptosis, migration, and invasion in melanoma by inhibiting MAPK and PI3K/AKT pathways. Cancer Med. 2017;6:819-833 pubmed 出版商
  • 免疫沉淀; 人类; 1:1000; 图 4d
  • 免疫印迹; 人类; 1:1000; 图 4d
Dong Q, Fu L, Zhao Y, Tan S, Wang E. Derlin-1 overexpression confers poor prognosis in muscle invasive bladder cancer and contributes to chemoresistance and invasion through PI3K/AKT and ERK/MMP signaling. Oncotarget. 2017;8:17059-17069 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2b
Kang Y, Balter B, Csizmadia E, Haas B, Sharma H, Bronson R, et al. Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival. Nat Commun. 2017;8:14013 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6c
Yang J, Savvatis K, Kang J, Fan P, Zhong H, Schwartz K, et al. Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment. Nat Commun. 2016;7:13710 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s9a
Karki R, Man S, Malireddi R, Kesavardhana S, Zhu Q, Burton A, et al. NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer. Nature. 2016;540:583-587 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Sikander M, Hafeez B, Malik S, Alsayari A, Halaweish F, Yallapu M, et al. Cucurbitacin D exhibits potent anti-cancer activity in cervical cancer. Sci Rep. 2016;6:36594 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1c
Sheen M, Marotti J, Allegrezza M, Rutkowski M, Conejo Garcia J, Fiering S. Constitutively activated PI3K accelerates tumor initiation and modifies histopathology of breast cancer. Oncogenesis. 2016;5:e267 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Visuttijai K, Pettersson J, Mehrbani Azar Y, van den Bout I, Orndal C, Marcickiewicz J, et al. Lowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT. PLoS ONE. 2016;11:e0164063 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 1
Cizmecioglu O, Ni J, Xie S, Zhao J, Roberts T. Rac1-mediated membrane raft localization of PI3K/p110? is required for its activation by GPCRs or PTEN loss. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 图 s1
Yuzugullu H, Von T, Thorpe L, Walker S, Roberts T, Frank D, et al. NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K-AKT and JAK-STAT3 pathways. Cell Discov. 2016;2:16030 pubmed 出版商
  • 免疫印迹; 人类; 图 5A
Di Franco S, Turdo A, Benfante A, Colorito M, Gaggianesi M, Apuzzo T, et al. ?Np63 drives metastasis in breast cancer cells via PI3K/CD44v6 axis. Oncotarget. 2016;7:54157-54173 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4c,4d
  • 免疫印迹; 人类; 1:1000; 图 5,6
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 7e
Xi R, Pan S, Chen X, Hui B, Zhang L, Fu S, et al. HPV16 E6-E7 induces cancer stem-like cells phenotypes in esophageal squamous cell carcinoma through the activation of PI3K/Akt signaling pathway in vitro and in vivo. Oncotarget. 2016;7:57050-57065 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Voisinne G, García Blesa A, Chaoui K, Fiore F, Bergot E, Girard L, et al. Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation. Mol Syst Biol. 2016;12:876 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
Jacobsen R, Mazloumi Gavgani F, Mellgren G, Lewis A. DNA Topoisomerase II? contributes to the early steps of adipogenesis in 3T3-L1 cells. Cell Signal. 2016;28:1593-603 pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Monica V, Lo Iacono M, Bracco E, Busso S, di Blasio L, Primo L, et al. Dasatinib modulates sensitivity to pemetrexed in malignant pleural mesothelioma cell lines. Oncotarget. 2016;7:76577-76589 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
Qiu X, Wei R, Li Y, Zhu Q, Xiong C, Chen Y, et al. NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner. Oncotarget. 2016;7:31440-53 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Zwang N, Zhang R, Germana S, Fan M, Hastings W, Cao A, et al. Selective Sparing of Human Tregs by Pharmacologic Inhibitors of the Phosphatidylinositol 3-Kinase and MEK Pathways. Am J Transplant. 2016;16:2624-38 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Lynch J, McEwen R, Crafter C, McDermott U, Garnett M, Barry S, et al. Identification of differential PI3K pathway target dependencies in T-cell acute lymphoblastic leukemia through a large cancer cell panel screen. Oncotarget. 2016;7:22128-39 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 4
  • 免疫组化-石蜡切片; 人类; 图 7
Du L, Chen X, Cao Y, Lu L, Zhang F, Bornstein S, et al. Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFβ signaling. Oncogene. 2016;35:4641-52 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 s5
Yamano S, Gi M, Tago Y, Doi K, Okada S, Hirayama Y, et al. Role of deltaNp63(pos)CD44v(pos) cells in the development of N-nitroso-tris-chloroethylurea-induced peripheral-type mouse lung squamous cell carcinomas. Cancer Sci. 2016;107:123-32 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3
  • 免疫印迹; 人类; 图 3
Munkley J, Livermore K, McClurg U, Kalna G, Knight B, McCullagh P, et al. The PI3K regulatory subunit gene PIK3R1 is under direct control of androgens and repressed in prostate cancer cells. Oncoscience. 2015;2:755-64 pubmed
  • 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 s1
Yuzugullu H, Baitsch L, Von T, Steiner A, Tong H, Ni J, et al. A PI3K p110β-Rac signalling loop mediates Pten-loss-induced perturbation of haematopoiesis and leukaemogenesis. Nat Commun. 2015;6:8501 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Kitatani K, Usui T, Sriraman S, Toyoshima M, Ishibashi M, Shigeta S, et al. Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid. Oncogene. 2016;35:2801-12 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Okoro E, Zhang H, Guo Z, Yang F, Smith C, Yang H. A Subregion of Reelin Suppresses Lipoprotein-Induced Cholesterol Accumulation in Macrophages. PLoS ONE. 2015;10:e0136895 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 3
Geletu M, Guy S, Greer S, Raptis L. Differential effects of polyoma virus middle tumor antigen mutants upon gap junctional, intercellular communication. Exp Cell Res. 2015;336:223-31 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Stoy C, Sundaram A, Rios Garcia M, Wang X, Seibert O, Zota A, et al. Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy. EMBO Mol Med. 2015;7:1048-62 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Cheng H, Liang Y, Kuo Y, Chuu C, Lin C, Lee M, et al. Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis. 2015;6:e1753 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Zhang W, Hou J, Wang X, Jiang R, Yin Y, Ji J, et al. PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis. Oncotarget. 2015;6:9420-33 pubmed
  • 免疫印迹; 大鼠; 图 4
Zhang Z, Zhang T, Zhou Y, Wei X, Zhu J, Zhang J, et al. Activated phosphatidylinositol 3-kinase/Akt inhibits the transition of endothelial progenitor cells to mesenchymal cells by regulating the forkhead box subgroup O-3a signaling. Cell Physiol Biochem. 2015;35:1643-53 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Zhou Q, Derti A, Ruddy D, Rakiec D, Kao I, Lira M, et al. A chemical genetics approach for the functional assessment of novel cancer genes. Cancer Res. 2015;75:1949-58 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Lin Y, Yang Z, Xu A, Dong P, Huang Y, Liu H, et al. PIK3R1 negatively regulates the epithelial-mesenchymal transition and stem-like phenotype of renal cancer cells through the AKT/GSK3β/CTNNB1 signaling pathway. Sci Rep. 2015;5:8997 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1
You J, Yang H, Lai Y, Simon L, Au J, Burkart A. AT-rich interactive domain 2, p110α, p53, and β-catenin protein expression in hepatocellular carcinoma and clinicopathologic implications. Hum Pathol. 2015;46:583-92 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Aki S, Yoshioka K, Okamoto Y, Takuwa N, Takuwa Y. Phosphatidylinositol 3-kinase class II α-isoform PI3K-C2α is required for transforming growth factor β-induced Smad signaling in endothelial cells. J Biol Chem. 2015;290:6086-105 pubmed 出版商
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Modelska A, Turro E, Russell R, Beaton J, Sbarrato T, Spriggs K, et al. The malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape. Cell Death Dis. 2015;6:e1603 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Gasser J, Inuzuka H, Lau A, Wei W, Beroukhim R, Toker A. SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer. Mol Cell. 2014;56:595-607 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Wang C, Zhang W, Fu M, Yang A, Huang H, Xie J. Establishment of human pancreatic cancer gemcitabine‑resistant cell line with ribonucleotide reductase overexpression. Oncol Rep. 2015;33:383-90 pubmed 出版商
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Perez García V, Redondo Muñoz J, Kumar A, Carrera A. Cell activation-induced phosphoinositide 3-kinase alpha/beta dimerization regulates PTEN activity. Mol Cell Biol. 2014;34:3359-73 pubmed 出版商
  • 免疫印迹; 大鼠; 图 1
Leinders M, Koehrn F, Bartok B, Boyle D, Shubayev V, Kalcheva I, et al. Differential distribution of PI3K isoforms in spinal cord and dorsal root ganglia: potential roles in acute inflammatory pain. Pain. 2014;155:1150-60 pubmed 出版商
  • 免疫印迹; 人类
Barceló C, Paco N, Beckett A, Alvarez Moya B, Garrido E, Gelabert M, et al. Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status. J Cell Sci. 2013;126:4553-9 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Kodigepalli K, Dutta P, Bauckman K, Nanjundan M. SnoN/SkiL expression is modulated via arsenic trioxide-induced activation of the PI3K/AKT pathway in ovarian cancer cells. FEBS Lett. 2013;587:5-16 pubmed 出版商
Takeda A, Maher T, Zhang Y, Lanahan S, Bucklin M, Compton S, et al. Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology. Nat Commun. 2019;10:4364 pubmed 出版商
Wu R, Young I, Chen Y, Chuang S, Toubaji A, Wu M. Identification of the PTEN-ARID4B-PI3K pathway reveals the dependency on ARID4B by PTEN-deficient prostate cancer. Nat Commun. 2019;10:4332 pubmed 出版商
Lopez Tello J, Perez García V, Khaira J, Kusinski L, Cooper W, Andreani A, et al. Fetal and trophoblast PI3K p110α have distinct roles in regulating resource supply to the growing fetus in mice. elife. 2019;8: pubmed 出版商
Koirala P, Huang J, Ho T, Wu F, Ding X, Mo Y. LncRNA AK023948 is a positive regulator of AKT. Nat Commun. 2017;8:14422 pubmed 出版商
Ischenko I, Zhi J, Hayman M, Petrenko O. KRAS-dependent suppression of MYC enhances the sensitivity of cancer cells to cytotoxic agents. Oncotarget. 2017;8:17995-18009 pubmed 出版商
Moniz L, Surinova S, Ghazaly E, Velasco L, Haider S, Rodríguez Prados J, et al. Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate. Sci Rep. 2017;7:39985 pubmed 出版商
Henry W, Laszewski T, Tsang T, Beca F, Beck A, McAllister S, et al. Aspirin Suppresses Growth in PI3K-Mutant Breast Cancer by Activating AMPK and Inhibiting mTORC1 Signaling. Cancer Res. 2017;77:790-801 pubmed 出版商
Gao H, Chen Z, Fu Y, Yang X, Weng R, Wang R, et al. Nur77 exacerbates PC12 cellular injury in vitro by aggravating mitochondrial impairment and endoplasmic reticulum stress. Sci Rep. 2016;6:34403 pubmed 出版商
Zhao X, Liu Y, Zhou L, Wang Z, Wu Z, Yang X. Role of estrogen in lung cancer based on the estrogen receptor-epithelial mesenchymal transduction signaling pathways. Onco Targets Ther. 2015;8:2849-63 pubmed 出版商
Song H, Kim J, Lee J, Nho K, Jeong H, Kim J, et al. Pik3ip1 modulates cardiac hypertrophy by inhibiting PI3K pathway. PLoS ONE. 2015;10:e0122251 pubmed 出版商
Haddad A, Kapur P, Singla N, Raman J, Then M, Nuhn P, et al. Validation of mammalian target of rapamycin biomarker panel in patients with clear cell renal cell carcinoma. Cancer. 2015;121:43-50 pubmed 出版商
Roy A, Modi K, Khasnavis S, Ghosh S, Watson R, Pahan K. Enhancement of morphological plasticity in hippocampal neurons by a physically modified saline via phosphatidylinositol-3 kinase. PLoS ONE. 2014;9:e101883 pubmed 出版商
Ong Q, Chan E, Lim M, Wong B. Expression of human apolipoprotein E4 reduces insulin-receptor substrate 1 expression and Akt phosphorylation in the ageing liver. FEBS Open Bio. 2014;4:260-5 pubmed 出版商
Wang L, Hu H, Pan Y, Wang R, Li Y, Shen L, et al. PIK3CA mutations frequently coexist with EGFR/KRAS mutations in non-small cell lung cancer and suggest poor prognosis in EGFR/KRAS wildtype subgroup. PLoS ONE. 2014;9:e88291 pubmed 出版商
Murata Y, Minami Y, Iwakawa R, Yokota J, Usui S, Tsuta K, et al. ECT2 amplification and overexpression as a new prognostic biomarker for early-stage lung adenocarcinoma. Cancer Sci. 2014;105:490-7 pubmed 出版商
Zhang J, Zhang Z, Zhang D, Zhu J, Zhang T, Wang C. microRNA 126 inhibits the transition of endothelial progenitor cells to mesenchymal cells via the PIK3R2-PI3K/Akt signalling pathway. PLoS ONE. 2013;8:e83294 pubmed 出版商
Sacco J, Yau T, Darling S, Patel V, Liu H, Urbé S, et al. The deubiquitylase Ataxin-3 restricts PTEN transcription in lung cancer cells. Oncogene. 2014;33:4265-72 pubmed 出版商
Wang W, Xie Y, Zhou Z, Qin Z, Wu J, He J. PIK3CA hypomethylation plays a key role in activation of the PI3K/AKT pathway in esophageal cancer in Chinese patients. Acta Pharmacol Sin. 2013;34:1560-7 pubmed 出版商
Le Floc h A, Tanaka Y, Bantilan N, Voisinne G, Altan Bonnet G, Fukui Y, et al. Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse. J Exp Med. 2013;210:2721-37 pubmed 出版商
Yip W, Choo C, Leong V, Leong P, Jabar M, Seow H. Molecular alterations of Ras-Raf-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt signaling pathways in colorectal cancers from a tertiary hospital at Kuala Lumpur, Malaysia. APMIS. 2013;121:954-66 pubmed 出版商
Tinker A, Ellard S, Welch S, Moens F, Allo G, Tsao M, et al. Phase II study of temsirolimus (CCI-779) in women with recurrent, unresectable, locally advanced or metastatic carcinoma of the cervix. A trial of the NCIC Clinical Trials Group (NCIC CTG IND 199). Gynecol Oncol. 2013;130:269-74 pubmed 出版商
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产品信息
SKU号 :
4249S
产品名称 :
磷脂酰肌醇(-3)激酶p110α(C73F8)兔单克隆抗体
规格 :
100微升
Price-(USD) :
235美元
物种x :
H, M, R, B
应用 :
免疫组化(石蜡)
产品种类 :
PI3K / Akt Signaling
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
110
宿主 :
靶标 :
PI3K p110甲
最初蛋白 :
PIK3CA
别名 :
MGC142161,MGC142163,PI3-kinase p110 subunit alpha,PI3-kinase subunit alpha,PI3K,PI3K-alpha,PIK3CA,PK3CA,Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha,Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform,PtdIns-3-kinase p110,PtdIns-3-kinase subunit alpha,PtdIns-3-kinase subunit p110-alpha,p110-alpha,phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha,phosphatidylinositol 3-kinase, catalytic, alpha polypeptide,phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform,phosphoinositide-3-kinase, catalytic, alpha polypeptide
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。