产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Notch1(D6F11)XP®兔单克隆抗体
目录 :
4380
克隆性 :
单克隆
宿主 :
共轭标签 :
未共轭
克隆名称 :
D6F11
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫印迹基因敲除验证
文章摘录数: 34
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 2f
Liu Y, Wang X, Deng L, Ping L, Shi Y, Zheng W, et al. ITK inhibition induced in vitro and in vivo anti-tumor activity through downregulating TCR signaling pathway in malignant T cell lymphoma. Cancer Cell Int. 2019;19:32 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 5b
Ma Q, Wang Y, Zhang T, Zuo W. Notch-mediated Sox9+ cell activation contributes to kidney repair after partial nephrectomy. Life Sci. 2018;193:104-109 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s3a
Bhardwaj A, Yang Y, Ueberheide B, Smith S. Whole proteome analysis of human tankyrase knockout cells reveals targets of tankyrase-mediated degradation. Nat Commun. 2017;8:2214 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2c
Lim J, Ibaseta A, Fischer M, Cancilla B, O Young G, Cristea S, et al. Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Nature. 2017;545:360-364 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 1c
Wang Y, Shen R, Han B, Li Z, Xiong L, Zhang F, et al. Notch signaling mediated by TGF-?/Smad pathway in concanavalin A-induced liver fibrosis in rats. World J Gastroenterol. 2017;23:2330-2336 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 1-s1f
Sawaguchi S, Varshney S, Ogawa M, Sakaidani Y, Yagi H, Takeshita K, et al. O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals. elife. 2017;6: pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 图 4d
  • 免疫组化; 大鼠; 1:100; 图 1d
  • 免疫印迹; 大鼠; 1:500; 图 1a
Zeng W, Han Y, Zhu G, Huang L, Deng Y, Wang Q, et al. Hypertonic saline attenuates expression of Notch signaling and proinflammatory mediators in activated microglia in experimentally induced cerebral ischemia and hypoxic BV-2 microglia. BMC Neurosci. 2017;18:32 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3a
Krepler C, Xiao M, Samanta M, Vultur A, Chen H, Brafford P, et al. Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma. Oncotarget. 2016;7:71211-71222 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2e
Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Deskin B, Lasky J, Zhuang Y, Shan B. Requirement of HDAC6 for activation of Notch1 by TGF-?1. Sci Rep. 2016;6:31086 pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Zhang S, Schneider L, Vick B, Grunert M, Jeremias I, Menche D, et al. Anti-leukemic effects of the V-ATPase inhibitor Archazolid A. Oncotarget. 2015;6:43508-28 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5a
Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, et al. The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS Genet. 2015;11:e1005503 pubmed 出版商
  • 免疫印迹; 人类; 1:2000
Gomi K, Arbelaez V, Crystal R, Walters M. Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway. PLoS ONE. 2015;10:e0116507 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Kaushik G, Venugopal A, Ramamoorthy P, Standing D, Subramaniam D, Umar S, et al. Honokiol inhibits melanoma stem cells by targeting notch signaling. Mol Carcinog. 2015;54:1710-21 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Dong X, Lin Q, Aihara A, Li Y, Huang C, Chung W, et al. Aspartate β-Hydroxylase expression promotes a malignant pancreatic cellular phenotype. Oncotarget. 2015;6:1231-48 pubmed
  • 免疫印迹; 人类
So J, Lin J, Wahler J, Liby K, Sporn M, Suh N. A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer. PLoS ONE. 2014;9:e107616 pubmed 出版商
  • 免疫细胞化学; 猪; 1:200
  • 免疫印迹; 猪; 1:1000
Qin L, Xu J, Wu Z, Zhang Z, Li J, Wang C, et al. Notch1-mediated signaling regulates proliferation of porcine satellite cells (PSCs). Cell Signal. 2013;25:561-9 pubmed 出版商
Kounatidou E, Nakjang S, McCracken S, Dehm S, Robson C, Jones D, et al. A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. Nucleic Acids Res. 2019;47:5634-5647 pubmed 出版商
Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al. A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer. Cell. 2019;177:1330-1345.e18 pubmed 出版商
Meyer K, Feldman H, Lu T, Drake D, Lim E, Ling K, et al. REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease. Cell Rep. 2019;26:1112-1127.e9 pubmed 出版商
Takeda D, Spisak S, Seo J, Bell C, O CONNOR E, Korthauer K, et al. A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer. Cell. 2018;174:422-432.e13 pubmed 出版商
Guarnieri A, Towers C, Drasin D, Oliphant M, Andrysik Z, Hotz T, et al. The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L. Oncogene. 2018;37:3879-3893 pubmed 出版商
Zheng Y, Wang Z, Ding X, Zhang W, Li G, Liu L, et al. A novel Notch1 missense mutation (C1133Y) in the Abruptex domain exhibits enhanced proliferation and invasion in oral squamous cell carcinoma. Cancer Cell Int. 2018;18:6 pubmed 出版商
Duex J, Swain K, Dancik G, Paucek R, Owens C, Churchill M, et al. Functional Impact of Chromatin Remodeling Gene Mutations and Predictive Signature for Therapeutic Response in Bladder Cancer. Mol Cancer Res. 2018;16:69-77 pubmed 出版商
Scher H, Graf R, Schreiber N, McLaughlin B, Jendrisak A, Wang Y, et al. Phenotypic Heterogeneity of Circulating Tumor Cells Informs Clinical Decisions between AR Signaling Inhibitors and Taxanes in Metastatic Prostate Cancer. Cancer Res. 2017;77:5687-5698 pubmed 出版商
Dai K, Huang L, Huang Y, Chen Z, Yang L, Jiang Y. 1810011o10 Rik Inhibits the Antitumor Effect of Intratumoral CD8+ T Cells through Suppression of Notch2 Pathway in a Murine Hepatocellular Carcinoma Model. Front Immunol. 2017;8:320 pubmed 出版商
Thomas J, Longen C, Oyer H, Chen N, Maher C, Salvino J, et al. Sigma1 Targeting to Suppress Aberrant Androgen Receptor Signaling in Prostate Cancer. Cancer Res. 2017;77:2439-2452 pubmed 出版商
Tse B, Volpert M, Ratther E, Stylianou N, Nouri M, McGowan K, et al. Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality. Oncogene. 2017;36:3417-3427 pubmed 出版商
Jue C, Zhifeng W, Zhisheng Z, Lin C, Yayun Q, Feng J, et al. Vasculogenic mimicry in hepatocellular carcinoma contributes to portal vein invasion. Oncotarget. 2016;7:77987-77997 pubmed 出版商
Crespo M, van Dalum G, Ferraldeschi R, Zafeiriou Z, Sideris S, Lorente D, et al. Androgen receptor expression in circulating tumour cells from castration-resistant prostate cancer patients treated with novel endocrine agents. Br J Cancer. 2015;112:1166-74 pubmed 出版商
Yu M, Jiang M, Yang C, Wu Y, Liu Y, Cui Y, et al. Maternal high-fat diet affects Msi/Notch/Hes signaling in neural stem cells of offspring mice. J Nutr Biochem. 2014;25:227-31 pubmed 出版商
Kluk M, Ashworth T, Wang H, Knoechel B, Mason E, Morgan E, et al. Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry. PLoS ONE. 2013;8:e67306 pubmed 出版商
Nie H, Cao Q, Zhu L, Gong Y, Gu J, He Z. Acetylcholine acts on androgen receptor to promote the migration and invasion but inhibit the apoptosis of human hepatocarcinoma. PLoS ONE. 2013;8:e61678 pubmed 出版商
Ao J, Meng J, Zhu L, Nie H, Yang C, Li J, et al. Activation of androgen receptor induces ID1 and promotes hepatocellular carcinoma cell migration and invasion. Mol Oncol. 2012;6:507-15 pubmed 出版商
产品信息
SKU号 :
4380P
产品名称 :
Notch1(D6F11)XP®兔单克隆抗体
规格 :
40微升
Price-(USD) :
135美元
物种x :
H, M, R
应用 :
流式细胞仪
产品种类 :
发育生物学
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
120, 300
宿主 :
靶标 :
Notch1
最初蛋白 :
Notch 1
别名 :
NOTC1,NOTCH1,Neurogenic locus notch homolog protein 1,Notch 1,Notch 1 extracellular truncation,Notch 1 intracellular domain,Notch homolog 1, translocation-associated (Drosophila),TAN1,Translocation-associated notch protein TAN-1,hN1
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。