出版应用/物种/样本/稀释 | 参考文献 |
---|
| Laine A, Nagelli S, Farrington C, Butt U, Cvrljevic A, Vainonen J, et al. CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis. Cancer Res. 2021;81:4319-4331 pubmed 出版商
|
| Sato M, Kadomatsu T, Miyata K, Warren J, Tian Z, Zhu S, et al. The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis. Nat Commun. 2021;12:2529 pubmed 出版商
|
| Santos Barriopedro I, Li Y, Bahl S, Seto E. HDAC8 affects MGMT levels in glioblastoma cell lines via interaction with the proteasome receptor ADRM1. Genes Cancer. 2019;10:119-133 pubmed 出版商
|
- 免疫印迹; 人类; 图 1d
- 免疫印迹; 小鼠; 图 6c
| Song Y, Lu H, Wang Q, Xiang R. Targeting Angiogenesis by Blocking the ATM-SerRS-VEGFA Pathway for UV-Induced Skin Photodamage and Melanoma Growth. Cancers (Basel). 2019;11: pubmed 出版商
|
| Gross K, Zhou W, Breindel J, Ouyang J, Jin D, Sokol E, et al. Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium. Cell Rep. 2019;28:394-407.e6 pubmed 出版商
|
| Zhou Z, Wang L, Ge F, Gong P, Wang H, Wang F, et al. Pold3 is required for genomic stability and telomere integrity in embryonic stem cells and meiosis. Nucleic Acids Res. 2018;46:3468-3486 pubmed 出版商
|
- 免疫细胞化学; 大鼠; 1:100; 图 2
- 免疫印迹; 大鼠; 1:500; 图 2
| Mata Garrido J, Casafont I, Tapia O, Berciano M, Lafarga M. Neuronal accumulation of unrepaired DNA in a novel specific chromatin domain: structural, molecular and transcriptional characterization. Acta Neuropathol Commun. 2016;4:41 pubmed 出版商
|
| Huang R, Langdon S, Tse M, Mullen P, Um I, Faratian D, et al. The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer. Oncotarget. 2016;7:4695-711 pubmed 出版商
|
| Harley M, Murina O, Leitch A, Higgs M, Bicknell L, Yigit G, et al. TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism. Nat Genet. 2016;48:36-43 pubmed 出版商
|
| Cristini A, Park J, Capranico G, Legube G, Favre G, Sordet O. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res. 2016;44:1161-78 pubmed 出版商
|
| Kanu N, Zhang T, Burrell R, Chakraborty A, Cronshaw J, DaCosta C, et al. RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress. Oncogene. 2016;35:4009-19 pubmed 出版商
|
| Hausmann C, Temme A, Cordes N, Eke I. ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation. Oncotarget. 2015;6:34592-605 pubmed 出版商
|
| Guo Y, Feng W, Sy S, Huen M. ATM-dependent Phosphorylation of the Fanconi Anemia Protein PALB2 Promotes the DNA Damage Response. J Biol Chem. 2015;290:27545-56 pubmed 出版商
|
| Seko Y, Fujimura T, Yao T, Taka H, Mineki R, Okumura K, et al. Secreted tyrosine sulfated-eIF5A mediates oxidative stress-induced apoptosis. Sci Rep. 2015;5:13737 pubmed 出版商
|
- 免疫印迹; 猕猴; 图 2
- 免疫印迹; pigs ; 图 2
| Simões M, Martins C, Ferreira F. Early intranuclear replication of African swine fever virus genome modifies the landscape of the host cell nucleus. Virus Res. 2015;210:1-7 pubmed 出版商
|
| Rein K, Yanez D, Terré B, Palenzuela L, Aivio S, Wei K, et al. EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele. Nucleic Acids Res. 2015;43:7371-87 pubmed 出版商
|
| Wu C, Huang K, Yang T, Li Y, Wen C, Hsu S, et al. The Topoisomerase 1 Inhibitor Austrobailignan-1 Isolated from Koelreuteria henryi Induces a G2/M-Phase Arrest and Cell Death Independently of p53 in Non-Small Cell Lung Cancer Cells. PLoS ONE. 2015;10:e0132052 pubmed 出版商
|
| Neumann J, Yang Y, Köhler R, Giaisi M, Witzens Harig M, Liu D, et al. Mangrove dolabrane-type of diterpenes tagalsins suppresses tumor growth via ROS-mediated apoptosis and ATM/ATR-Chk1/Chk2-regulated cell cycle arrest. Int J Cancer. 2015;137:2739-48 pubmed 出版商
|
| Batenburg N, Thompson E, Hendrickson E, Zhu X. Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation. EMBO J. 2015;34:1399-416 pubmed 出版商
|
- 免疫细胞化学; 小鼠; 图 3
- 免疫印迹; 小鼠; 1:1000; 图 3
| Boersma V, Moatti N, Segura Bayona S, Peuscher M, van der Torre J, Wevers B, et al. MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection. Nature. 2015;521:537-540 pubmed 出版商
|
- 免疫印迹; 人类; 1:1000; 图 1,2,3,4,5,6,7
| Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, et al. Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy. EMBO J. 2015;34:1214-30 pubmed 出版商
|
| Ruan X, Zuo Q, Jia H, Chau J, Lin J, Ao J, et al. P53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers. J Mol Cell Biol. 2015;7:105-18 pubmed 出版商
|
| Brazina J, Svadlenka J, Macurek L, Andera L, Hodny Z, Bartek J, et al. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase. Cell Cycle. 2015;14:375-87 pubmed 出版商
|
| Chen Y, Wei M, Wang C, Lee H, Pan S, Gao M, et al. Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor is an effective radiosensitizer for colorectal cancer. Cancer Lett. 2015;357:582-90 pubmed 出版商
|
| Osterman M, Kathawa D, Liu D, Guo H, Zhang C, Li M, et al. Elevated DNA damage response in pancreatic cancer. Histochem Cell Biol. 2014;142:713-20 pubmed 出版商
|
- 免疫细胞化学; 人类; 1:50
- 免疫印迹; 人类; 1:1000
| Nikitin P, Price A, McFadden K, Yan C, Luftig M. Mitogen-induced B-cell proliferation activates Chk2-dependent G1/S cell cycle arrest. PLoS ONE. 2014;9:e87299 pubmed 出版商
|
| Sappino A, Buser R, Seguin Q, Fernet M, Lesne L, Gumy Pause F, et al. The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damage. Oncogenesis. 2012;1:e7 pubmed 出版商
|
- 免疫细胞化学; 人类
- 免疫印迹; 人类; 1:1000
| Penicud K, Behrens A. DMAP1 is an essential regulator of ATM activity and function. Oncogene. 2014;33:525-31 pubmed 出版商
|
| Jullien L, Mestre M, Roux P, Gire V. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. Nucleic Acids Res. 2013;41:900-11 pubmed 出版商
|
| Douarre C, Sourbier C, Dalla Rosa I, Brata Das B, Redon C, Zhang H, et al. Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism. PLoS ONE. 2012;7:e41094 pubmed 出版商
|
| Sampadi B, Pines A, Munk S, Misovic B, de Groot A, van de Water B, et al. Quantitative phosphoproteomics to unravel the cellular response to chemical stressors with different modes of action. Arch Toxicol. 2020;94:1655-1671 pubmed 出版商
|
| Jaiswal H, Benada J, Müllers E, Akopyan K, Burdova K, Koolmeister T, et al. ATM/Wip1 activities at chromatin control Plk1 re-activation to determine G2 checkpoint duration. EMBO J. 2017;36:2161-2176 pubmed 出版商
|
| Hodroj D, Recolin B, Serhal K, Martinez S, Tsanov N, Abou Merhi R, et al. An ATR-dependent function for the Ddx19 RNA helicase in nuclear R-loop metabolism. EMBO J. 2017;36:1182-1198 pubmed 出版商
|
| Ho T, Guilbaud G, Blow J, Sale J, Watson C. The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability. Cell Rep. 2016;15:724-734 pubmed 出版商
|
| Young L, Marzio A, Pérez Durán P, Reid D, Meredith D, Roberti D, et al. TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage Response. Cell Rep. 2015;13:451-459 pubmed 出版商
|
| Liang H, Esposito A, De S, Ber S, Collin P, Surana U, et al. Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing. Nat Commun. 2014;5:4048 pubmed 出版商
|
| Singh R, Shankar B, Sainis K. TGF-?1-ROS-ATM-CREB signaling axis in macrophage mediated migration of human breast cancer MCF7 cells. Cell Signal. 2014;26:1604-15 pubmed 出版商
|
| Ogara M, Belluscio L, de la Fuente V, Berardino B, Sonzogni S, Byk L, et al. CDK5-mediated phosphorylation of p19INK4d avoids DNA damage-induced neurodegeneration in mouse hippocampus and prevents loss of cognitive functions. Biochim Biophys Acta. 2014;1843:1309-24 pubmed 出版商
|
| Jin Y, An G, Ni J, Li S, Jia H. ATM-dependent E2F1 accumulation in the nucleolus is an indicator of ribosomal stress in early response to DNA damage. Cell Cycle. 2014;13:1627-38 pubmed 出版商
|
| Inoue A, Kikuchi S, Hishiki A, Shao Y, Heath R, Evison B, et al. A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin. J Biol Chem. 2014;289:7109-20 pubmed 出版商
|
| Adelman C, Lolo R, Birkbak N, Murina O, Matsuzaki K, Horejsi Z, et al. HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature. 2013;502:381-4 pubmed 出版商
|
| Chen Y, Kamili A, Hardy J, Groblewski G, Khanna K, Byrne J. Tumor protein D52 represents a negative regulator of ATM protein levels. Cell Cycle. 2013;12:3083-97 pubmed 出版商
|
| Zhang L, Chen H, Gong M, Gong F. The chromatin remodeling protein BRG1 modulates BRCA1 response to UV irradiation by regulating ATR/ATM activation. Front Oncol. 2013;3:7 pubmed 出版商
|
| Wang Z, Inuzuka H, Zhong J, Fukushima H, Wan L, Liu P, et al. DNA damage-induced activation of ATM promotes ?-TRCP-mediated Mdm2 ubiquitination and destruction. Oncotarget. 2012;3:1026-35 pubmed
|
| Hawkes W, Printsev I, Alkan Z. Selenoprotein W depletion induces a p53- and p21-dependent delay in cell cycle progression in RWPE-1 prostate epithelial cells. J Cell Biochem. 2012;113:61-9 pubmed 出版商
|
| Sánchez Molina S, Mortusewicz O, Bieber B, Auer S, Eckey M, Leonhardt H, et al. Role for hACF1 in the G2/M damage checkpoint. Nucleic Acids Res. 2011;39:8445-56 pubmed 出版商
|
| Sims J, Wade P. Mi-2/NuRD complex function is required for normal S phase progression and assembly of pericentric heterochromatin. Mol Biol Cell. 2011;22:3094-102 pubmed 出版商
|
| Schmidt W, Uddin M, Dysek S, Moser Thier K, Pirker C, Hoger H, et al. DNA damage, somatic aneuploidy, and malignant sarcoma susceptibility in muscular dystrophies. PLoS Genet. 2011;7:e1002042 pubmed 出版商
|
| Nikitin P, Yan C, Forte E, Bocedi A, Tourigny J, White R, et al. An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells. Cell Host Microbe. 2010;8:510-22 pubmed 出版商
|
| Jurado S, Smyth I, van Denderen B, Tenis N, Hammet A, Hewitt K, et al. Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis. PLoS Genet. 2010;6:e1001170 pubmed 出版商
|
| Zhu H, Yue J, Pan Z, Wu H, Cheng Y, Lu H, et al. Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining. PLoS ONE. 2010;5:e12055 pubmed 出版商
|