产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
Mcl-1 Antibody
目录 :
4572
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠
应用 :
免疫印迹
文章摘录数: 37
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 人类; 图 1a
Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed 出版商
  • 免疫印迹; 人类; 图 5c
Guo A, Lu P, Lee J, Zhen C, Chiosis G, Wang Y. HSP90 stabilizes B-cell receptor kinases in a multi-client interactome: PU-H71 induces CLL apoptosis in a cytoprotective microenvironment. Oncogene. 2017;36:3441-3449 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Zhang Y, Zhang Y, Zhong C, Xiao F. Cr(VI) induces premature senescence through ROS-mediated p53 pathway in L-02 hepatocytes. Sci Rep. 2016;6:34578 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Zhao J, Niu X, Li X, Edwards H, Wang G, Wang Y, et al. Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells. Oncotarget. 2016;7:34785-99 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Kim H, Oh J, Choi S, Nam Y, Jo A, Kwon A, et al. Down-regulation of p21-activated serine/threonine kinase 1 is involved in loss of mesencephalic dopamine neurons. Mol Brain. 2016;9:45 pubmed 出版商
  • 免疫印迹; 人类; 图 s6
Kline C, van den Heuvel A, Allen J, Prabhu V, Dicker D, El Deiry W. ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases. Sci Signal. 2016;9:ra18 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Crowder R, Dicker D, El Deiry W. The Deubiquitinase Inhibitor PR-619 Sensitizes Normal Human Fibroblasts to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-mediated Cell Death. J Biol Chem. 2016;291:5960-70 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2d
Ko T, Chin H, Chuah C, Huang J, Ng K, Khaw S, et al. The BIM deletion polymorphism: A paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia. Oncotarget. 2016;7:2721-33 pubmed 出版商
  • 免疫印迹; 人类; 图 5g
Fedorenko I, Abel E, Koomen J, Fang B, Wood E, Chen Y, et al. Fibronectin induction abrogates the BRAF inhibitor response of BRAF V600E/PTEN-null melanoma cells. Oncogene. 2016;35:1225-35 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Zucal C, D Agostino V, Casini A, Mantelli B, Thongon N, Soncini D, et al. EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition. BMC Cancer. 2015;15:855 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Wu C, Huang K, Yang T, Li Y, Wen C, Hsu S, et al. The Topoisomerase 1 Inhibitor Austrobailignan-1 Isolated from Koelreuteria henryi Induces a G2/M-Phase Arrest and Cell Death Independently of p53 in Non-Small Cell Lung Cancer Cells. PLoS ONE. 2015;10:e0132052 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Lu H, Xue Y, Xue Y, Yu G, Arias C, Lin J, et al. Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism. elife. 2015;4:e06535 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Cerella C, Muller F, Gaigneaux A, Radogna F, Viry E, Chateauvieux S, et al. Early downregulation of Mcl-1 regulates apoptosis triggered by cardiac glycoside UNBS1450. Cell Death Dis. 2015;6:e1782 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Kushwaha D, O Leary C, Cron K, Deraska P, Zhu K, D Andrea A, et al. USP9X inhibition promotes radiation-induced apoptosis in non-small cell lung cancer cells expressing mid-to-high MCL1. Cancer Biol Ther. 2015;16:392-401 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1i
Feng T, Dzieran J, Gu X, Marhenke S, Vogel A, Machida K, et al. Smad7 regulates compensatory hepatocyte proliferation in damaged mouse liver and positively relates to better clinical outcome in human hepatocellular carcinoma. Clin Sci (Lond). 2015;128:761-74 pubmed 出版商
  • 免疫印迹; 人类
Cazanave S, Wang X, Zhou H, Rahmani M, Grant S, Durrant D, et al. Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis. Cell Death Differ. 2014;21:1303-12 pubmed 出版商
Bahr J, Robey R, Luchenko V, Basseville A, Chakraborty A, Kozlowski H, et al. Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras. Oncotarget. 2016;7:69804-69815 pubmed 出版商
Frederick D, Salas Fragomeni R, Schalck A, Ferreiro Neira I, Hoff T, Cooper Z, et al. Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics. PLoS ONE. 2014;9:e101286 pubmed 出版商
Su J, Tseng P, Hsu C, Tai W, Huang J, Ko C, et al. RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells. Oncotarget. 2014;5:4909-19 pubmed
Colak S, Zimberlin C, Fessler E, Hogdal L, Prasetyanti P, Grandela C, et al. Decreased mitochondrial priming determines chemoresistance of colon cancer stem cells. Cell Death Differ. 2014;21:1170-7 pubmed 出版商
Francis S, Taylor C, Tang T, Liu Z, Zheng Q, Dondero R, et al. SNS01-T modulation of eIF5A inhibits B-cell cancer progression and synergizes with bortezomib and lenalidomide. Mol Ther. 2014;22:1643-52 pubmed 出版商
Lin W, Yeh T, Jiaang W, Yen K, Chen C, Huang C, et al. Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer. PLoS ONE. 2014;9:e83160 pubmed 出版商
Pandey M, Gowda K, Doi K, Sharma A, Wang H, Amin S. Proteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cells. PLoS ONE. 2013;8:e78570 pubmed 出版商
Guo X, Dong Y, Yin S, Zhao C, Huo Y, Fan L, et al. Patulin induces pro-survival functions via autophagy inhibition and p62 accumulation. Cell Death Dis. 2013;4:e822 pubmed 出版商
Cawley K, Logue S, Gorman A, Zeng Q, Patterson J, Gupta S, et al. Disruption of microRNA biogenesis confers resistance to ER stress-induced cell death upstream of the mitochondrion. PLoS ONE. 2013;8:e73870 pubmed 出版商
van Dijk M, Halpin McCormick A, Sessler T, Samali A, Szegezdi E. Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways. Cell Death Dis. 2013;4:e702 pubmed 出版商
Wu Y, Crawford M, Mao Y, Lee R, Davis I, Elton T, et al. Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer. Mol Ther Nucleic Acids. 2013;2:e84 pubmed 出版商
Amir S, Ma A, Shi X, Xue L, Kung H, deVere White R. Oncomir miR-125b suppresses p14(ARF) to modulate p53-dependent and p53-independent apoptosis in prostate cancer. PLoS ONE. 2013;8:e61064 pubmed 出版商
Tian Y, Nam S, Liu L, Yakushijin F, Yakushijin K, Buettner R, et al. Spirooxindole derivative SOID-8 induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells. PLoS ONE. 2012;7:e49306 pubmed 出版商
Orzáez M, Guevara T, Sancho M, Perez Paya E. Intrinsic caspase-8 activation mediates sensitization of erlotinib-resistant tumor cells to erlotinib/cell-cycle inhibitors combination treatment. Cell Death Dis. 2012;3:e415 pubmed 出版商
Engesæter B, Engebraaten O, Flørenes V, Mælandsmo G. Dacarbazine and the agonistic TRAIL receptor-2 antibody lexatumumab induce synergistic anticancer effects in melanoma. PLoS ONE. 2012;7:e45492 pubmed 出版商
Xiang X, Phung Y, Feng M, Nagashima K, Zhang J, Broaddus V, et al. The development and characterization of a human mesothelioma in vitro 3D model to investigate immunotoxin therapy. PLoS ONE. 2011;6:e14640 pubmed 出版商
Rubert J, Qian Z, Andraos R, Guthy D, Radimerski T. Bim and Mcl-1 exert key roles in regulating JAK2V617F cell survival. BMC Cancer. 2011;11:24 pubmed 出版商
Flamant L, Notte A, Ninane N, Raes M, Michiels C. Anti-apoptotic role of HIF-1 and AP-1 in paclitaxel exposed breast cancer cells under hypoxia. Mol Cancer. 2010;9:191 pubmed 出版商
Ocio E, Maiso P, Chen X, Garayoa M, Alvarez Fernández S, San Segundo L, et al. Zalypsis: a novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to DNA double-strand breaks. Blood. 2009;113:3781-91 pubmed 出版商
Roccaro A, Leleu X, Sacco A, Moreau A, Hatjiharissi E, Jia X, et al. Resveratrol exerts antiproliferative activity and induces apoptosis in Waldenström's macroglobulinemia. Clin Cancer Res. 2008;14:1849-58 pubmed 出版商
Roccaro A, Leleu X, Sacco A, Jia X, Melhem M, Moreau A, et al. Dual targeting of the proteasome regulates survival and homing in Waldenstrom macroglobulinemia. Blood. 2008;111:4752-63 pubmed 出版商
产品信息
SKU号 :
4572S
产品名称 :
Mcl-1 Antibody
规格 :
100微升
Price-(USD) :
235美元
物种x :
H
应用 :
免疫印迹
产品种类 :
凋亡
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
多克隆抗体
分子量 :
40
宿主 :
靶标 :
髓细胞白血病-1基因
最初蛋白 :
髓细胞白血病-1基因
别名 :
BCL2L3,Bcl-2-like protein 3,Bcl-2-related protein EAT/mcl1,Bcl2-L-3,EAT,Induced myeloid leukemia cell differentiation protein Mcl-1,MCL1,MCL1L,MCL1S,MGC104264,MGC1839,Mcl-1,TM,mcl1/EAT,myeloid cell leukemia ES,myeloid cell leukemia sequence 1 (BCL2-related),myeloid cell leukemia sequence 1, isoform 1
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。