产品简要
公司名称 :
赛信通(上海)生物试剂有限公司
产品类型 :
抗体
产品名称 :
NF-κB p65(C22B4)兔单克隆抗体
目录 :
4764
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
C22B4
反应物种 :
人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
文章摘录数: 149
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:2000; 图 1g
Parodi B, Sanna A, Cedola A, Uccelli A, Kerlero de Rosbo N. Hydroxycarboxylic Acid Receptor 2, a Pleiotropically Linked Receptor for the Multiple Sclerosis Drug, Monomethyl Fumarate. Possible Implications for the Inflammatory Response. Front Immunol. 2021;12:655212 pubmed 出版商
  • 免疫细胞化学; 牛; 图 1c
  • 免疫印迹; 人类; 图 2a
Nakayama A, Albarrán Juárez J, Liang G, Roquid K, Iring A, Tonack S, et al. Disturbed flow-induced Gs-mediated signaling protects against endothelial inflammation and atherosclerosis. JCI Insight. 2020;5: pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 4e
Mishra P, Boutej H, Soucy G, Bareil C, Kumar S, Picher Martel V, et al. Transmission of ALS pathogenesis by the cerebrospinal fluid. Acta Neuropathol Commun. 2020;8:65 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6d
Viau A, Baaziz M, Aka A, Mazloum M, Nguyen C, Kuehn E, et al. Tubular STAT3 Limits Renal Inflammation in Autosomal Dominant Polycystic Kidney Disease. J Am Soc Nephrol. 2020;31:1035-1049 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6d
Lindner P, Paul S, Eckstein M, Hampel C, Muenzner J, Erlenbach Wuensch K, et al. EMT transcription factor ZEB1 alters the epigenetic landscape of colorectal cancer cells. Cell Death Dis. 2020;11:147 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 10a
Jiang L, Xu K, Li J, Zhou X, Xu L, Wu Z, et al. Nesfatin-1 suppresses interleukin-1β-induced inflammation, apoptosis, and cartilage matrix destruction in chondrocytes and ameliorates osteoarthritis in rats. Aging (Albany NY). 2020;12:1760-1777 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3i
Yue D, Zhao J, Chen H, Guo M, Chen C, Zhou Y, et al. MicroRNA-7, synergizes with RORα, negatively controls the pathology of brain tissue inflammation. J Neuroinflammation. 2020;17:28 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Zhang Q, Xiang L, Zaman M, Dong W, He G, Deng G. Predominant Role of Immunoglobulin G in the Pathogenesis of Splenomegaly in Murine Lupus. Front Immunol. 2019;10:3020 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Jobin P, Solis N, Machado Y, Bell P, Kwon N, Kim S, et al. Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase. J Biol Chem. 2019;294:12866-12879 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6b
  • 免疫印迹; 人类; 图 6f
Mentrup T, Theodorou K, Cabrera Cabrera F, Helbig A, Happ K, Gijbels M, et al. Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis. J Exp Med. 2019;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 9c
Zhou L, Chen X, Lu M, Wu Q, Yuan Q, Hu C, et al. Wnt/β-catenin links oxidative stress to podocyte injury and proteinuria. Kidney Int. 2019;95:830-845 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4b
Ye P, Liu J, Xu W, Liu D, Ding X, Le S, et al. Dual-Specificity Phosphatase 26 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through Transforming Growth Factor Beta-Activated Kinase 1 Suppression. Hepatology. 2019;69:1946-1964 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Luong P, Hedl M, Yan J, Zuo T, Fu T, Jiang X, et al. INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling. elife. 2018;7: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s6a
Cuchet Lourenço D, Eletto D, Wu C, Plagnol V, Papapietro O, CURTIS J, et al. Biallelic RIPK1 mutations in humans cause severe immunodeficiency, arthritis, and intestinal inflammation. Science. 2018;361:810-813 pubmed 出版商
  • 免疫印迹; 小鼠; 图 8a
  • 免疫印迹; 大鼠; 图 7a
Miyasato Y, Yoshizawa T, Sato Y, Nakagawa T, Miyasato Y, Kakizoe Y, et al. Sirtuin 7 Deficiency Ameliorates Cisplatin-induced Acute Kidney Injury Through Regulation of the Inflammatory Response. Sci Rep. 2018;8:5927 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Yang L, Shen L, Gao P, Li G, He Y, Wang M, et al. Effect of AMPK signal pathway on pathogenesis of abdominal aortic aneurysms. Oncotarget. 2017;8:92827-92840 pubmed 出版商
  • 免疫印迹; 人类; 图 1e
Liu L, Jiang Y, Chahine A, Curtiss E, Steinle J. Epac1 agonist decreased inflammatory proteins in retinal endothelial cells, and loss of Epac1 increased inflammatory proteins in the retinal vasculature of mice. Mol Vis. 2017;23:1-7 pubmed
  • 免疫印迹; 小鼠; 图 7c
Xiong X, Liu Y, Mei Y, Peng J, Wang Z, Kong B, et al. Novel Protective Role of Myeloid Differentiation 1 in Pathological Cardiac Remodelling. Sci Rep. 2017;7:41857 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6d
Chao M, Guo J, Cheng W, Zhu X, She Z, Huang Z, et al. Loss of Caspase-Activated DNase Protects Against Atherosclerosis in Apolipoprotein E-Deficient Mice. J Am Heart Assoc. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 图 4b
Omsland M, Bruserud Ã, Gjertsen B, Andresen V. Tunneling nanotube (TNT) formation is downregulated by cytarabine and NF-κB inhibition in acute myeloid leukemia (AML). Oncotarget. 2017;8:7946-7963 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 4b
  • 免疫印迹; 小鼠; 图 4a
Klaska I, Muckersie E, Martin Granados C, Christofi M, Forrester J. Lipopolysaccharide-primed heterotolerant dendritic cells suppress experimental autoimmune uveoretinitis by multiple mechanisms. Immunology. 2017;150:364-377 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5c
  • 免疫印迹; 小鼠; 图 5a
Zhao J, Chen C, Guo M, Tao Y, Cui P, Zhou Y, et al. MicroRNA-7 Deficiency Ameliorates the Pathologies of Acute Lung Injury through Elevating KLF4. Front Immunol. 2016;7:389 pubmed
  • 免疫印迹; 小鼠; 图 6d
Kennedy T, Swiderski K, Murphy K, Gehrig S, Curl C, Chandramouli C, et al. BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle. Am J Pathol. 2016;186:3246-3260 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3c
  • 免疫印迹; 人类; 图 4c
Chen R, Xie Y, Zhong X, Fu Y, Huang Y, Zhen Y, et al. Novel chemokine-like activities of histones in tumor metastasis. Oncotarget. 2016;7:61728-61740 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2a
Bettaieb A, Cremonini E, Kang H, Kang J, Haj F, Oteiza P. Anti-inflammatory actions of (-)-epicatechin in the adipose tissue of obese mice. Int J Biochem Cell Biol. 2016;81:383-392 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4c
Kim J, Weeratunga P, Kim M, Nikapitiya C, Lee B, Uddin M, et al. Inhibitory effects of an aqueous extract from Cortex Phellodendri on the growth and replication of broad-spectrum of viruses in vitro and in vivo. BMC Complement Altern Med. 2016;16:265 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5a
Song X, Yao Z, Yang J, Zhang Z, Deng Y, Li M, et al. HCV core protein binds to gC1qR to induce A20 expression and inhibit cytokine production through MAPKs and NF-κB signaling pathways. Oncotarget. 2016;7:33796-808 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Lin A, Wang G, Zhao H, Zhang Y, Han Q, Zhang C, et al. TLR4 signaling promotes a COX-2/PGE2/STAT3 positive feedback loop in hepatocellular carcinoma (HCC) cells. Oncoimmunology. 2016;5:e1074376 pubmed
  • 免疫细胞化学; 小鼠; 图 5a
  • 免疫印迹; 小鼠; 图 5b
Dang Y, Mu Y, Wang K, Xu K, Yang J, Zhu Y, et al. Papaverine inhibits lipopolysaccharide-induced microglial activation by suppressing NF-κB signaling pathway. Drug Des Devel Ther. 2016;10:851-9 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Wang P, Zhang X, Luo P, Jiang X, Zhang P, Guo J, et al. Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling. Nat Commun. 2016;7:10592 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3
Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 3a
  • 免疫印迹; 人类; 图 2b
Lu S, Natarajan S, Mott J, Kharbanda K, Harrison Findik D. Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway. PLoS ONE. 2016;11:e0147474 pubmed 出版商
  • 免疫印迹; 人类
Theendakara V, Peters Libeu C, Spilman P, Poksay K, Bredesen D, Rao R. Direct Transcriptional Effects of Apolipoprotein E. J Neurosci. 2016;36:685-700 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 6
  • 免疫细胞化学; 小鼠; 1:200; 图 2
  • 免疫印迹; 小鼠; 1:1000; 图 2
Wu H, Shi L, Wang Q, Cheng L, Zhao X, Chen Q, et al. Mumps virus-induced innate immune responses in mouse Sertoli and Leydig cells. Sci Rep. 2016;6:19507 pubmed 出版商
  • 免疫印迹; 人类; 图 s1
Klein T, Fung S, Renner F, Blank M, Dufour A, Kang S, et al. The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling. Nat Commun. 2015;6:8777 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Liu C, Zheng L, Wang H, Ran X, Liu H, Sun X. The RCAN1 inhibits NF-κB and suppresses lymphoma growth in mice. Cell Death Dis. 2015;6:e1929 pubmed 出版商
  • 免疫印迹; 小鼠
He L, Zang A, Du M, Ma D, Yuan C, Zhou C, et al. mTOR regulates TLR-induced c-fos and Th1 responses to HBV and HCV vaccines. Virol Sin. 2015;30:174-89 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Wang Y, Lian Q, Yang B, Yan S, Zhou H, He L, et al. TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING. PLoS Pathog. 2015;11:e1005012 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 4
Dille S, Kleinschnitz E, Kontchou C, Nölke T, Häcker G. In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport. Infect Immun. 2015;83:3268-80 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图  6
Revuelta López E, Cal R, Herraiz Martínez A, De Gonzalo Calvo D, Nasarre L, Roura S, et al. Hypoxia-driven sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) downregulation depends on low-density lipoprotein receptor-related protein 1 (LRP1)-signalling in cardiomyocytes. J Mol Cell Cardiol. 2015;85:25-36 pubmed 出版商
  • 免疫印迹; 人类
Katanov C, Lerrer S, Liubomirski Y, Leider Trejo L, Meshel T, Bar J, et al. Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-? and the NF-?B pathway. Stem Cell Res Ther. 2015;6:87 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000
Parodi B, Rossi S, Morando S, Cordano C, Bragoni A, Motta C, et al. Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS. Acta Neuropathol. 2015;130:279-95 pubmed 出版商
  • 免疫印迹; 小鼠
Bao M, Cai Z, Zhang X, Li L, Liu X, Wan N, et al. Dickkopf-3 protects against cardiac dysfunction and ventricular remodelling following myocardial infarction. Basic Res Cardiol. 2015;110:25 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3
Xu H, Cho S, Bang M, Bae C, Choi Y, Li Y, et al. FK-3000 isolated from Stephania delavayi Diels. inhibits MDA-MB-231 cell proliferation by decreasing NF-κB phosphorylation and COX-2 expression. Int J Oncol. 2015;46:2309-16 pubmed 出版商
  • 免疫印迹; 小鼠; 图 10A
Pone E, Lam T, Lou Z, Wang R, Chen Y, Liu D, et al. B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses. J Immunol. 2015;194:3065-78 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 5c
Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed 出版商
  • 免疫印迹; 大鼠
Yang D, Sun Y, Bhaumik S, Li Y, Baumann J, Lin X, et al. Blocking lymphocyte trafficking with FTY720 prevents inflammation-sensitized hypoxic-ischemic brain injury in newborns. J Neurosci. 2014;34:16467-81 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Huang L, Zhang S, Zhang P, Zhang X, Zhu L, Chen K, et al. Interferon regulatory factor 7 protects against vascular smooth muscle cell proliferation and neointima formation. J Am Heart Assoc. 2014;3:e001309 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7
Lu H, Clauser K, Tam W, Fröse J, Ye X, Eaton E, et al. A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages. Nat Cell Biol. 2014;16:1105-17 pubmed 出版商
  • 免疫印迹; 人类
Tang J, Shen L, Yang Q, Zhang C. Overexpression of metadherin mediates metastasis of osteosarcoma by regulating epithelial-mesenchymal transition. Cell Prolif. 2014;47:427-34 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Yang L, Kan E, Lu J, Wu C, Ling E. Expression of 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) and its roles in activated microglia in vivo and in vitro. J Neuroinflammation. 2014;11:148 pubmed 出版商
  • 免疫印迹; 小鼠
Bartuzi P, Wijshake T, Dekker D, Fedoseienko A, Kloosterhuis N, Youssef S, et al. A cell-type-specific role for murine Commd1 in liver inflammation. Biochim Biophys Acta. 2014;1842:2257-65 pubmed 出版商
  • 免疫印迹; 人类; 图 3, 4, 5
Kobayashi T, Masoumi K, Massoumi R. Deubiquitinating activity of CYLD is impaired by SUMOylation in neuroblastoma cells. Oncogene. 2015;34:2251-60 pubmed 出版商
  • 免疫印迹; 人类
Olesen J, Gliemann L, Biensø R, Schmidt J, Hellsten Y, Pilegaard H. Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men. J Physiol. 2014;592:1873-86 pubmed 出版商
  • 免疫印迹; 大鼠; 1:2000
Zhang Q, Pan Y, Wang R, Kang L, Xue Q, Wang X, et al. Quercetin inhibits AMPK/TXNIP activation and reduces inflammatory lesions to improve insulin signaling defect in the hypothalamus of high fructose-fed rats. J Nutr Biochem. 2014;25:420-8 pubmed 出版商
  • 免疫印迹; 人类; 图 6D
Bohonowych J, Hance M, Nolan K, DEFEE M, Parsons C, Isaacs J. Extracellular Hsp90 mediates an NF-?B dependent inflammatory stromal program: implications for the prostate tumor microenvironment. Prostate. 2014;74:395-407 pubmed 出版商
  • 酶联免疫吸附测定; 人类
Lee W, Ku S, Min B, Lee S, Jee J, Kim J, et al. Vascular barrier protective effects of pellitorine in LPS-induced inflammation in vitro and in vivo. Fitoterapia. 2014;92:177-87 pubmed 出版商
  • 免疫印迹; 小鼠
Hou J, Xia Y, Jiang R, Chen D, Xu J, Deng L, et al. PTPRO plays a dual role in hepatic ischemia reperfusion injury through feedback activation of NF-?B. J Hepatol. 2014;60:306-12 pubmed 出版商
  • 免疫组化; 小鼠
  • 免疫印迹; 小鼠
Tan C, Tan E, Luo B, Huang C, Loo J, Choong C, et al. SMAD3 deficiency promotes inflammatory aortic aneurysms in angiotensin II-infused mice via activation of iNOS. J Am Heart Assoc. 2013;2:e000269 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200
  • 免疫印迹; 小鼠; 1:1000
Yan K, Zhu W, Yu L, Li N, Zhang X, Liu P, et al. Toll-like receptor 3 and RIG-I-like receptor activation induces innate antiviral responses in mouse ovarian granulosa cells. Mol Cell Endocrinol. 2013;372:73-85 pubmed 出版商
  • 免疫印迹; 小鼠
Dai J, Shen D, Bian Z, Zhou H, Gan H, Zong J, et al. IKKi deficiency promotes pressure overload-induced cardiac hypertrophy and fibrosis. PLoS ONE. 2013;8:e53412 pubmed 出版商
  • 免疫组化; 大鼠
Pranski E, Dalal N, Sanford C, Herskowitz J, Gearing M, Lazo C, et al. RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-?B signaling in dopaminergic cells. Neurobiol Dis. 2013;54:264-79 pubmed 出版商
  • 免疫细胞化学; 人类
Newman A, Scholefield C, Kemp A, Newman M, McIver E, Kamal A, et al. TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. PLoS ONE. 2012;7:e50672 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s2
Wu L, Shao L, An N, Wang J, Pazhanisamy S, Feng W, et al. IKK? regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells. PLoS ONE. 2011;6:e18447 pubmed 出版商
Seo J, Jin M, Chang Y. Anti-inflammatory effect of Salsola komarovii extract with dissociated glucocorticoid activity. BMC Complement Med Ther. 2020;20:176 pubmed 出版商
Wang H, Fu L, Cheng C, Gao R, Lin M, Su H, et al. Inhibition of LPS-Induced Oxidative Damages and Potential Anti-Inflammatory Effects of Phyllanthus emblica Extract via Down-Regulating NF-κB, COX-2, and iNOS in RAW 264.7 Cells. Antioxidants (Basel). 2019;8: pubmed 出版商
Kim J, Yoon J, Nikapitiya C, Kim T, Uddin M, Lee H, et al. Small Heterodimer Partner Controls the Virus-Mediated Antiviral Immune Response by Targeting CREB-Binding Protein in the Nucleus. Cell Rep. 2019;27:2105-2118.e5 pubmed 出版商
Shaverdashvili K, Padlo J, Weinblatt D, Jia Y, Jiang W, Rao D, et al. KLF4 activates NFκB signaling and esophageal epithelial inflammation via the Rho-related GTP-binding protein RHOF. PLoS ONE. 2019;14:e0215746 pubmed 出版商
Stempel M, Chan B, Juranic Lisnic V, Krmpotic A, Hartung J, Paludan S, et al. The herpesviral antagonist m152 reveals differential activation of STING-dependent IRF and NF-κB signaling and STING's dual role during MCMV infection. EMBO J. 2019;38: pubmed 出版商
Serresi M, Siteur B, Hulsman D, Company C, Schmitt M, Lieftink C, et al. Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities. J Exp Med. 2018;215:3115-3135 pubmed 出版商
Yan N, Wen D, Zhao Y, Xu S. Epimedium sagittatum inhibits TLR4/MD-2 mediated NF-κB signaling pathway with anti-inflammatory activity. BMC Complement Altern Med. 2018;18:303 pubmed 出版商
Albarrán Juárez J, Iring A, Wang S, Joseph S, Grimm M, Strilic B, et al. Piezo1 and Gq/G11 promote endothelial inflammation depending on flow pattern and integrin activation. J Exp Med. 2018;215:2655-2672 pubmed 出版商
Travers J, Rochman M, Miracle C, Habel J, Brusilovsky M, Caldwell J, et al. Chromatin regulates IL-33 release and extracellular cytokine activity. Nat Commun. 2018;9:3244 pubmed 出版商
De Nardo D, Balka K, Cardona Gloria Y, Rao V, Latz E, Masters S. Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling. J Biol Chem. 2018;293:15195-15207 pubmed 出版商
Hunt D, Drake L, Drake J. Murine macrophage TLR2-FcγR synergy via FcγR licensing of IL-6 cytokine mRNA ribosome binding and translation. PLoS ONE. 2018;13:e0200764 pubmed 出版商
Li Q, Dai C, Xue R, Wang P, Chen L, Han Y, et al. S100A4 Protects Myeloid-Derived Suppressor Cells from Intrinsic Apoptosis via TLR4-ERK1/2 Signaling. Front Immunol. 2018;9:388 pubmed 出版商
Wakamatsu T, Yamamoto S, Ito T, Sato Y, Matsuo K, Takahashi Y, et al. Indoxyl Sulfate Promotes Macrophage IL-1β Production by Activating Aryl Hydrocarbon Receptor/NF-κ/MAPK Cascades, but the NLRP3 inflammasome Was Not Activated. Toxins (Basel). 2018;10: pubmed 出版商
Gunasekaran M, Sharma M, Hachem R, Bremner R, Smith M, Mohanakumar T. Circulating Exosomes with Distinct Properties during Chronic Lung Allograft Rejection. J Immunol. 2018;200:2535-2541 pubmed 出版商
Ooki A, Begum A, Marchionni L, Vandenbussche C, Mao S, Kates M, et al. Arsenic promotes the COX2/PGE2-SOX2 axis to increase the malignant stemness properties of urothelial cells. Int J Cancer. 2018;143:113-126 pubmed 出版商
Rao S, Sigl V, Wimmer R, Novatchkova M, Jais A, Wagner G, et al. RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer. Genes Dev. 2017;31:2099-2112 pubmed 出版商
Edwards R, Luis P, Varuzza P, Joseph A, Presley S, Chaturvedi R, et al. The anti-inflammatory activity of curcumin is mediated by its oxidative metabolites. J Biol Chem. 2017;292:21243-21252 pubmed 出版商
Wu A, Tymoszuk P, Haschka D, Heeke S, Dichtl S, Petzer V, et al. Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages via Modulation of NF-κB Signaling. Infect Immun. 2017;85: pubmed 出版商
Wang W, Shi Q, Dou S, Li G, Shi X, Jiang X, et al. Negative regulation of Nod-like receptor protein 3 inflammasome activation by T cell Ig mucin-3 protects against peritonitis. Immunology. 2018;153:71-83 pubmed 出版商
Badran Y, Dedeoglu F, Leyva Castillo J, Bainter W, Ohsumi T, Bousvaros A, et al. Human RELA haploinsufficiency results in autosomal-dominant chronic mucocutaneous ulceration. J Exp Med. 2017;214:1937-1947 pubmed 出版商
Giusto M, Barberi L, Di Sario F, Rizzuto E, Nicoletti C, Ascenzi F, et al. Skeletal muscle myopenia in mice model of bile duct ligation and carbon tetrachloride-induced liver cirrhosis. Physiol Rep. 2017;5: pubmed 出版商
Ganesan R, Hos N, Gutierrez S, Fischer J, Stepek J, Daglidu E, et al. Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy. PLoS Pathog. 2017;13:e1006227 pubmed 出版商
Tan J, Tedrow J, Nouraie M, Dutta J, Miller D, Li X, et al. Loss of Twist1 in the Mesenchymal Compartment Promotes Increased Fibrosis in Experimental Lung Injury by Enhanced Expression of CXCL12. J Immunol. 2017;198:2269-2285 pubmed 出版商
Chan T, Hsu C, Pai V, Liao W, Huang S, Tan K, et al. Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells. J Exp Med. 2016;213:2967-2988 pubmed
Li T, Jin K, Zhu D, Li L, Mao Z, Wu B, et al. Premalignant alteration assessment in liver-like tissue derived from embryonic stem cells by aristolochic acid I exposure. Oncotarget. 2016;7:78872-78882 pubmed 出版商
Li Z, Chen Z, Zhang T, Wei C, Shi W. TGF-? and NF-?B signaling pathway crosstalk potentiates corneal epithelial senescence through an RNA stress response. Aging (Albany NY). 2016;8:2337-2354 pubmed 出版商
Xiang S, Zeng Y, Xiong B, Qin Y, Huang X, Jiang Y, et al. Transforming growth factor beta 1 induced endothelin-1 release is peroxisome proliferator-activated receptor gamma dependent in A549 cells. J Inflamm (Lond). 2016;13:19 pubmed 出版商
Lee A, Jung Y, Thanh T, Lee S, Kim W, Kang K, et al. Paricalcitol attenuates lipopolysaccharide-induced myocardial inflammation by regulating the NF-κB signaling pathway. Int J Mol Med. 2016;37:1023-9 pubmed 出版商
Price L, Shao D, Meng C, Perros F, Garfield B, Zhu J, et al. Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells. Respir Res. 2015;16:114 pubmed 出版商
Hou J, Ma J, Yu K, Li W, Cheng C, Bao L, et al. Non-thermal plasma treatment altered gene expression profiling in non-small-cell lung cancer A549 cells. BMC Genomics. 2015;16:435 pubmed 出版商
Zheng N, Wang D, Ming H, Zhang H, Yu X. BAFF promotes proliferation of human mesangial cells through interaction with BAFF-R. BMC Nephrol. 2015;16:72 pubmed 出版商
Sharma N, Verma R, Kumawat K, Basu A, Singh S. miR-146a suppresses cellular immune response during Japanese encephalitis virus JaOArS982 strain infection in human microglial cells. J Neuroinflammation. 2015;12:30 pubmed 出版商
Li C, Lun W, Zhao X, Lei S, Guo Y, Ma J, et al. Allicin alleviates inflammation of trinitrobenzenesulfonic acid-induced rats and suppresses P38 and JNK pathways in Caco-2 cells. Mediators Inflamm. 2015;2015:434692 pubmed 出版商
Yuan K, Yu H, Feng W, Chong P, Yang T, Xue C, et al. Bifidobacterium infantis has a beneficial effect on 5-fluorouracil-induced intestinal mucositis in rats. Benef Microbes. 2015;6:113-8 pubmed 出版商
Yue Y, Wang Y, Li D, Song Z, Jiao H, Lin H. A central role for the mammalian target of rapamycin in LPS-induced anorexia in mice. J Endocrinol. 2015;224:37-47 pubmed 出版商
Zhang X, Shi Y, Weng Y, Lai Q, Luo T, Zhao J, et al. The truncate mutation of Notch2 enhances cell proliferation through activating the NF-κB signal pathway in the diffuse large B-cell lymphomas. PLoS ONE. 2014;9:e108747 pubmed 出版商
Abdi J, Garssen J, Faber J, Redegeld F. Omega-3 fatty acids, EPA and DHA induce apoptosis and enhance drug sensitivity in multiple myeloma cells but not in normal peripheral mononuclear cells. J Nutr Biochem. 2014;25:1254-62 pubmed 出版商
Wang Q, Chu C, Qian L, Chen S, Wilson B, Oyarzabal E, et al. Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase. J Neurosci. 2014;34:12490-503 pubmed 出版商
Zagórska A, Través P, Lew E, Dransfield I, Lemke G. Diversification of TAM receptor tyrosine kinase function. Nat Immunol. 2014;15:920-8 pubmed 出版商
Luo X, Tai W, Sun L, Qiu Q, Xia Z, Chung S, et al. Central administration of C-X-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice. PLoS ONE. 2014;9:e104860 pubmed 出版商
Rodriguez M, Luo W, Weng J, Zeng L, Yi Z, Siwko S, et al. PSGR promotes prostatic intraepithelial neoplasia and prostate cancer xenograft growth through NF-κB. Oncogenesis. 2014;3:e114 pubmed 出版商
Sun Y, Li J, Xiao N, Wang M, Kou J, Qi L, et al. Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1. Pharmacol Res. 2014;89:19-28 pubmed 出版商
Yan J, Zhang H, Yin Y, Li J, Tang Y, Purkayastha S, et al. Obesity- and aging-induced excess of central transforming growth factor-? potentiates diabetic development via an RNA stress response. Nat Med. 2014;20:1001-8 pubmed 出版商
Liu C, Hong T, Shao M, Chen Z, Wang C. Melatonin synergized with cyclosporine A improves cardiac allograft survival by suppressing inflammation and apoptosis. Mol Med Rep. 2014;10:1323-8 pubmed 出版商
Yang J, Rui B, Chen C, Chen H, Xu T, Xu W, et al. Acetylsalicylic acid enhances the anti-inflammatory effect of fluoxetine through inhibition of NF-?B, p38-MAPK and ERK1/2 activation in lipopolysaccharide-induced BV-2 microglia cells. Neuroscience. 2014;275:296-304 pubmed 出版商
Wang B, Yang G, Liang X, Zhu M, Du M. Grape seed extract prevents skeletal muscle wasting in interleukin 10 knockout mice. BMC Complement Altern Med. 2014;14:162 pubmed 出版商
Li T, Guan J, Li S, Zhang X, Zheng X. HSCARG downregulates NF-?B signaling by interacting with USP7 and inhibiting NEMO ubiquitination. Cell Death Dis. 2014;5:e1229 pubmed 出版商
Padiya R, Chowdhury D, Borkar R, Srinivas R, Pal Bhadra M, Banerjee S. Garlic attenuates cardiac oxidative stress via activation of PI3K/AKT/Nrf2-Keap1 pathway in fructose-fed diabetic rat. PLoS ONE. 2014;9:e94228 pubmed 出版商
Peng Y, Xu R, Zheng X. HSCARG negatively regulates the cellular antiviral RIG-I like receptor signaling pathway by inhibiting TRAF3 ubiquitination via recruiting OTUB1. PLoS Pathog. 2014;10:e1004041 pubmed 出版商
Chen Z, Fu Q, Shen B, Huang X, Wang K, He P, et al. Enhanced p62 expression triggers concomitant autophagy and apoptosis in a rat chronic spinal cord compression model. Mol Med Rep. 2014;9:2091-6 pubmed 出版商
Liu M, Song S, Li H, Jiang X, Yin P, Wan C, et al. The protective effect of caffeic acid against inflammation injury of primary bovine mammary epithelial cells induced by lipopolysaccharide. J Dairy Sci. 2014;97:2856-65 pubmed 出版商
Leibovich Rivkin T, Liubomirski Y, Meshel T, Abashidze A, Brisker D, Solomon H, et al. The inflammatory cytokine TNF? cooperates with Ras in elevating metastasis and turns WT-Ras to a tumor-promoting entity in MCF-7 cells. BMC Cancer. 2014;14:158 pubmed 出版商
Zhao N, Wang R, Zhou L, Zhu Y, Gong J, Zhuang S. MicroRNA-26b suppresses the NF-?B signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3. Mol Cancer. 2014;13:35 pubmed 出版商
Wattenberg M, Kwilas A, Gameiro S, Dicker A, Hodge J. Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets. Br J Cancer. 2014;110:1472-80 pubmed 出版商
Lu N, Liu Q, Gu L, Ge S, Wu J, Ze Ji Q, et al. Gene Expression Profiles Underlying Selective T-Cell-Mediated Immunity Activity of a Chinese Medicine Granule on Mice Infected with Influenza Virus H1N1. Evid Based Complement Alternat Med. 2014;2014:976364 pubmed 出版商
Trojandt S, Reske Kunz A, Bros M. Geldanamycin-mediated inhibition of heat shock protein 90 partially activates dendritic cells, but interferes with their full maturation, accompanied by impaired upregulation of RelB. J Exp Clin Cancer Res. 2014;33:16 pubmed 出版商
Benz A, Renne C, Maronde E, Koch M, Grabiec U, Kallendrusch S, et al. Expression and functional relevance of cannabinoid receptor 1 in Hodgkin lymphoma. PLoS ONE. 2013;8:e81675 pubmed 出版商
Park Y, Yoon S, Suh H, Kim D, Park J, Jung H, et al. TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis. PLoS Pathog. 2013;9:e1003646 pubmed 出版商
Bruells C, Maes K, Rossaint R, Thomas D, Cielen N, Bleilevens C, et al. Prolonged mechanical ventilation alters the expression pattern of angio-neogenetic factors in a pre-clinical rat model. PLoS ONE. 2013;8:e70524 pubmed 出版商
Sun P, Zhou K, Wang S, Li P, Chen S, Lin G, et al. Involvement of MAPK/NF-κB signaling in the activation of the cholinergic anti-inflammatory pathway in experimental colitis by chronic vagus nerve stimulation. PLoS ONE. 2013;8:e69424 pubmed 出版商
Kempuraj D, Twait E, Williard D, Yuan Z, Meyerholz D, Samuel I. The novel cytokine interleukin-33 activates acinar cell proinflammatory pathways and induces acute pancreatic inflammation in mice. PLoS ONE. 2013;8:e56866 pubmed 出版商
Nicholson J, Puche A, Guo Y, Weinreich D, Slater B, Bernstein S. PGJ(2) provides prolonged CNS stroke protection by reducing white matter edema. PLoS ONE. 2012;7:e50021 pubmed 出版商
Ma C, Zuo W, Wang X, Wei L, Guo Q, Song X. Lapatinib inhibits the activation of NF-?B through reducing phosphorylation of I?B-? in breast cancer cells. Oncol Rep. 2013;29:812-8 pubmed 出版商
He Y, Zheng M, Ma Y, Han X, Ma X, Qu C, et al. Soluble oligomers and fibrillar species of amyloid ?-peptide differentially affect cognitive functions and hippocampal inflammatory response. Biochem Biophys Res Commun. 2012;429:125-30 pubmed 出版商
Lockwood C, Kayisli U, Stocco C, Murk W, Vatandaslar E, Buchwalder L, et al. Abruption-induced preterm delivery is associated with thrombin-mediated functional progesterone withdrawal in decidual cells. Am J Pathol. 2012;181:2138-48 pubmed 出版商
de Souza Reis F, de Faria F, Castro C, de Souza P, da Cunha Vasconcelos F, Bello R, et al. The therapeutical potential of a novel pterocarpanquinone LQB-118 to target inhibitor of apoptosis proteins in acute myeloid leukemia cells. Anticancer Agents Med Chem. 2013;13:341-51 pubmed
Cai Z, Yang F, Yu L, Yu Z, Jiang L, Wang Q, et al. Activated T cell exosomes promote tumor invasion via Fas signaling pathway. J Immunol. 2012;188:5954-61 pubmed 出版商
Liu C, Wang G, Chen G, Mu Y, Zhang L, Hu X, et al. Huangqi decoction inhibits apoptosis and fibrosis, but promotes Kupffer cell activation in dimethylnitrosamine-induced rat liver fibrosis. BMC Complement Altern Med. 2012;12:51 pubmed 出版商
Pranski E, Dalal N, Herskowitz J, Orr A, Roesch L, Fritz J, et al. Neuronal RING finger protein 11 (RNF11) regulates canonical NF-?B signaling. J Neuroinflammation. 2012;9:67 pubmed 出版商
Zhao H, Song C, Chai O. Negative effects of curcumin on liver injury induced by alcohol. Phytother Res. 2012;26:1857-63 pubmed 出版商
Lobo P, Bajwa A, Schlegel K, Vengal J, Lee S, Huang L, et al. Natural IgM anti-leukocyte autoantibodies attenuate excess inflammation mediated by innate and adaptive immune mechanisms involving Th-17. J Immunol. 2012;188:1675-85 pubmed 出版商
Hu P, Chu G, Zhu G, Yang H, Luthringer D, Prins G, et al. Multiplexed quantum dot labeling of activated c-Met signaling in castration-resistant human prostate cancer. PLoS ONE. 2011;6:e28670 pubmed 出版商
Wang H, Geng Q, Wang L, Lu Y. Curcumin potentiates antitumor activity of L-asparaginase via inhibition of the AKT signaling pathway in acute lymphoblastic leukemia. Leuk Lymphoma. 2012;53:1376-82 pubmed 出版商
Mackesy D, Goalstone M. Insulin augments tumor necrosis factor-alpha stimulated expression of vascular cell adhesion molecule-1 in vascular endothelial cells. J Inflamm (Lond). 2011;8:34 pubmed 出版商
Fukushima T, Kawaguchi M, Yorita K, Tanaka H, Takeshima H, Umezawa K, et al. Antitumor effect of dehydroxymethylepoxyquinomicin, a small molecule inhibitor of nuclear factor-?B, on glioblastoma. Neuro Oncol. 2012;14:19-28 pubmed 出版商
Soetikno V, Sari F, Veeraveedu P, Thandavarayan R, Harima M, Sukumaran V, et al. Curcumin ameliorates macrophage infiltration by inhibiting NF-?B activation and proinflammatory cytokines in streptozotocin induced-diabetic nephropathy. Nutr Metab (Lond). 2011;8:35 pubmed 出版商
Ikner A, Ashkenazi A. TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8. J Biol Chem. 2011;286:21546-54 pubmed 出版商
Cheung H, St Jean M, Beug S, Lejmi Mrad R, LaCasse E, Baird S, et al. SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds. Cell Death Dis. 2011;2:e146 pubmed 出版商
Stairs D, Bayne L, Rhoades B, Vega M, Waldron T, Kalabis J, et al. Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. Cancer Cell. 2011;19:470-83 pubmed 出版商
Yen H, Ooka T, Iguchi A, Hayashi T, Sugimoto N, Tobe T. NleC, a type III secretion protease, compromises NF-?B activation by targeting p65/RelA. PLoS Pathog. 2010;6:e1001231 pubmed 出版商
Xie S, Li J, Wang J, Wu Q, Yang P, Hsu H, et al. IL-17 activates the canonical NF-kappaB signaling pathway in autoimmune B cells of BXD2 mice to upregulate the expression of regulators of G-protein signaling 16. J Immunol. 2010;184:2289-96 pubmed 出版商
Reed J, Leon R, Hall M, Schwertfeger K. Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis. Breast Cancer Res. 2009;11:R21 pubmed 出版商
Hideshima T, Chauhan D, Kiziltepe T, Ikeda H, Okawa Y, Podar K, et al. Biologic sequelae of I{kappa}B kinase (IKK) inhibition in multiple myeloma: therapeutic implications. Blood. 2009;113:5228-36 pubmed 出版商
Hasler U, Leroy V, Jeon U, Bouley R, Dimitrov M, Kim J, et al. NF-kappaB modulates aquaporin-2 transcription in renal collecting duct principal cells. J Biol Chem. 2008;283:28095-105 pubmed 出版商
产品信息
SKU号 :
4764S
产品名称 :
NF-κB p65(C22B4)兔单克隆抗体
规格 :
100微升
Price-(USD) :
235美元
物种x :
H, M, R, Mk, B, (Dg)
应用 :
流式细胞仪
产品种类 :
免疫学和炎症
运输温度 :
AMBIENT
储存温度 :
-20°C
产品类型 :
单克隆抗体
分子量 :
65
宿主 :
靶标 :
NFkB-p65
最初蛋白 :
NFkB-p65
别名 :
MGC131774,NFKB3,Nuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3,RELA,TF65,Transcription factor p65,p65,v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)),v-rel reticuloendotheliosis viral oncogene homolog A (avian),v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65
公司信息
赛信通(上海)生物试剂有限公司
上海市浦东南路1101号远东大厦514室,200120
info@cst-c.com.cn
http://www.cst-c.com.cn
2158356288
公司总部: 美国
赛信通生物试剂有限公司1999年成立于美国麻省,是一家私人拥有的公司,在全世界拥有超过400名员工。我们致力于提供用于帮助确定的细胞功能和抗病机制的创新型的研究工具。公司自成立以来,赛信通已成为全球领先的生产用于扩大细胞信号通路知识的最高质量的激活状态蛋白和总蛋白的抗体。我们的使命是为客户提供世界上最高质量的研究工具,以加快生物研究和个性化药物的进展。